Application | Comment | Organism |
---|---|---|
synthesis | synthesis of astaxanthin. Astaxanthin is a carotenoid of significant commercial value due to its superior antioxidant potential and wide applications in the aquaculture, food, cosmetic and pharmaceutical industries. The Brevundimonas sp. SD212 crtW and Pantoea ananatis crtZ genes are the best combination for astaxanthin production. After balancing the activities of beta-carotene ketolase and hydroxylase, an Escherichia coli ASTA-1 that carries neither a plasmid nor an antibiotic marker is constructed to produce astaxanthin as the predominant carotenoid (96.6%) with a specific content of 7.4 mg/g dry cell weight without an addition of inducer | Pantoea ananatis |
Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Pantoea ananatis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 | Pantoea ananatis | the enzyme plays an important role in astaxanthin production | zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pantoea ananatis | D4GFL0 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 | - |
Pantoea ananatis | zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O | - |
? | |
beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 | the enzyme plays an important role in astaxanthin production | Pantoea ananatis | zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
beta-carotene hydroxylase | - |
Pantoea ananatis |
CrtZ | - |
Pantoea ananatis |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme plays an important role in astaxanthin production | Pantoea ananatis |