Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Iron | the enzyme is a non-heme di-iron protein | Arabidopsis thaliana |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | Q9LTG0 | ecotypes Columbia and Wassilewskija | - |
Arabidopsis thaliana | Q9SZZ8 | ecotypes Columbia and Wassilewskija | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leaf | - |
Arabidopsis thaliana | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha-carotene + reduced acceptor + H+ + O2 | - |
Arabidopsis thaliana | zeinoxanthin + acceptor + H2O | - |
? | |
beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 | - |
Arabidopsis thaliana | cryptoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O | - |
? | |
beta-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 | - |
Arabidopsis thaliana | zeaxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O | - |
? | |
cryptoxanthin + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 | - |
Arabidopsis thaliana | zeaxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O | - |
? | |
additional information | although beta-hydroxylase 1 is active toward beta-rings, it can also add a hydroxyl group to epsilon-rings in vitro, although at much lower efficiency | Arabidopsis thaliana | ? | - |
? | |
additional information | although beta-hydroxylase 2 is most active toward beta-rings, it can also add a hydroxyl group to epsilon-rings in vitro, although at much lower efficiency | Arabidopsis thaliana | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
beta-carotene hydroxylase | - |
Arabidopsis thaliana |
beta-hydroxylases 1 | - |
Arabidopsis thaliana |
beta-hydroxylases 2 | - |
Arabidopsis thaliana |
General Information | Comment | Organism |
---|---|---|
malfunction | in the homozygous b1 b2 double mutant both beta-hydroxylase activities are eliminated, but beta-ring-hydroxylated xanthophylls (L, V, and N) still are synthesized, albeit at lower levels than in ecotype Wassilewskija or in either single mutant. Xanthophylls N and V are reduced by 90 and 65%, respectively, and there is a 30% increase in xanthophyll L relative to ecotype Wassilewskija. As with the single beta-hydroxylase mutants, beta-carotene is unchanged relative to the wild type and beta-cryptoxanthin does not accumulate | Arabidopsis thaliana |
physiological function | beta-hydroxylase 1 and 2 are functionally redundant in vivo | Arabidopsis thaliana |