2.7.4.6: nucleoside-diphosphate kinase

This is an abbreviated version!
For detailed information about nucleoside-diphosphate kinase, go to the full flat file.

Word Map on EC 2.7.4.6

2.7.4.6

triphosphate

node

gdp

lymph

adenylate

metastases

tumour

autophosphorylation

colorectal

oncogene

drosophila

guanine

c-myc

clinicopathological

melanoma

creatine

dictyostelium

hexameric

gtp-binding

discoideum

non-metastatic

gamma-phosphate

anti-metastatic

heterotrimeric

phosphohistidine

transphosphorylation

dntp

deoxyribonucleoside

succinyl-coa

phosphoenzyme

metastasis-related

mastoparan

high-metastatic

metastasis-associated

prune

c-erbb-2

myxococcus

g-quadruplexes

deoxynucleoside

xanthus

medicine

drug development

Reaction

Synonyms

AfNDK, Afu5g03490, ASNDK, At4g09320, At4g11010, At5g63310, HsNDK, kinase, nucleoside diphosphate (phosphorylating), mitochondrial nucleoside diphosphate kinase, MJ1265, More, NDK, NDK B, NDK-1, NDKB, NDP kinase, NDP kinase A, NDP kinase alpha, NDP kinase beta, NDPK, NDPK B, NDPK I, NDPK II, NDPK III, NDPK IIpn, NDPK In, NDPK-3, NDPK-B, NDPK-C, NDPK-D, NDPK-In, NDPK1, NDPK2, NDPK3, NDPK3a, NDPKA, NDPKB, NM23, NM23 metastasis suppressor, Nm23-H1, NM23-H2, NM23-H4, NME1, NME2, NME3, NME4, nucleoside 5'-diphosphate kinase, nucleoside diphosphate (UDP) kinase, nucleoside diphosphate kinase, nucleoside diphosphate kinase 1, nucleoside diphosphate kinase 2, nucleoside diphosphate kinase 3, nucleoside diphosphate kinase 3a, nucleoside diphosphate kinase A, nucleoside diphosphate kinase B, nucleoside diphosphate kinase C, nucleoside diphosphate kinase D, nucleoside diphosphate kinase-1, nucleoside diphosphate kinase-2, nucleoside diphosphate kinases alpha, nucleoside diphosphate kinases beta, nucleoside diphosphate phosphotransferase, nucleoside diphosphokinase, nucleoside-diphosphate kinase 3, nucleotide diphosphate kinase, nucleotide phosphate kinase, ORF454, Os12g36194, OsNDPK2, SwoH, TcNDPK1, TcNDPK3, UDP kinase, uridine diphosphate kinase, WSL12, YSS2 protein

ECTree

2 Transferases

2.7 Transferring phosphorus-containing groups

2.7.4 Phosphotransferases with a phosphate group as acceptor

2.7.4.6 nucleoside-diphosphate kinase

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Results	in table
6	Activating Compound
51439	AA Sequence
6	Application
1	CAS Registry Number
97	Cloned(Commentary)
24	Cofactor
42	Crystallization (Commentary)
5761	Disease/ Diagnostics
7	Expression
56	General Information
12	General Stability
7	IC50 Value
46	Inhibitors
26	kcat/KM [mM/s]
1	Ki Value [mM]
136	KM Value [mM]
121	Localization
167	Metals/Ions
148	Molecular Weight [Da]
124	Natural Substrates/ Products (Substrates)
966	Organism
28	Pathway
770	PDB ID
61	pH Optimum
4	pH Range
7	pH Stability
19	pI Value
17	Posttranslational Modification
139	Protein Variants
92	Purification (Commentary)
26	Reaction
1	Reaction Type
283	Reference
8	Renatured (Commentary)
238	Source Tissue
79	Specific Activity [micromol/min/mg]
8	Storage Stability
725	Substrates and Products (Substrate)
186	Subunits
322	Synonyms
1	Systematic Name
39	Temperature Optimum [°C]
4	Temperature Range [°C]
46	Temperature Stability [°C]
29	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 2.7.4.6 - nucleoside-diphosphate kinase

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1.9

AMP

Mycobacterium tuberculosis

A5U5E1

IC50: 1.9 mM

662280

6 - 26.7

cAMP

2 entries

chromoglycate

Mycobacterium tuberculosis

A5U5E1

IC50: 90 mM

662280

0.002 - 0.003

ellagic acid

Homo sapiens

691523

0.008 - 0.01

epigallocatechin gallate

Homo sapiens

691523

1.6

UDP

Mycobacterium tuberculosis

A5U5E1

IC50: 1.6 mM

662280