Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ellagic acid | inhibits NDPK and suppresses MDA-MB-435S cell growth | Homo sapiens | |
epigallocatechin gallate | EGCG, inhibits NDPK and suppresses MDA-MB-435S cell growth | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | the enzyme is secreted | Homo sapiens | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + NDP | Homo sapiens | - |
ADP + NTP | - |
? | |
additional information | Homo sapiens | MDA-MB-435S cell-secreted NDPK-B supports tumour formation by modulating ATP levels locally to activate endothelial cell P2Y receptor-mediated angiogenesis, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
breast carcinoma cell | - |
Homo sapiens | - |
MDA-MB-435S cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + NDP | - |
Homo sapiens | ADP + NTP | - |
? | |
additional information | MDA-MB-435S cell-secreted NDPK-B supports tumour formation by modulating ATP levels locally to activate endothelial cell P2Y receptor-mediated angiogenesis, overview | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NDPK | - |
Homo sapiens |
nucleoside diphosphate kinase | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.002 | 0.003 | - |
Homo sapiens | ellagic acid | |
0.008 | 0.01 | - |
Homo sapiens | epigallocatechin gallate |