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Disease on EC 2.7.4.6 - nucleoside-diphosphate kinase

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DISEASE
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Adenocarcinoma
Altered expression of nm23-H1 and c-erbB-2 proteins have prognostic significance in adenocarcinoma but not in squamous cell carcinoma of the uterine cervix.
Changes in biomarker expression in the development of prostatic adenocarcinoma.
Clinicopathological features and prognostic significance of nucleoside diphosphate kinase/nm23 gene product in human pancreatic exocrine neoplasms.
Comparative proteomics analysis of Barrett metaplasia and esophageal adenocarcinoma using two-dimensional liquid mass mapping.
Estrogen and progestin regulate metastasis through the PI3K/AKT pathway in human ovarian cancer.
Expression and mutational analysis of Nm23-H1 in liver metastases of colorectal cancer.
Expression of antimetastatic gene nm23-H1 in epithelial ovarian cancer.
Expression of nm23-H1 and nm23-H2 protein in endometrial carcinoma.
Expression of nm23-H1 in prostatic intraepithelial neoplasia and adenocarcinoma.
Immunohistochemical analysis of nm23 gene product/NDP kinase expression in pulmonary adenocarcinoma: lack of prognostic value.
Impact of laparoscopy on the biological behavior and gene expression of endometrial adenocarcinoma cells.
Maspin and Nm23-H1 expression in colorectal cancer.
Mutation in the nm23 gene is associated with metastasis in colorectal cancer.
Mutation of the nm23-H1 gene has a non-dominant role in colorectal adenocarcinoma.
nm23-H1 expression and loss of heterozygosity in colon adenocarcinoma.
nm23-H1 protein immunoreactivity in cancers of the gallbladder, extrahepatic bile ducts and ampulla of Vater.
Prognostic implication of nm23-H1 expression in colorectal carcinomas.
Prognostic significance of the loss of heterozygosity of Nm23-H1 and p53 genes in human colorectal carcinomas.
Reduced metastatic potential and c-myc overexpression of colon adenocarcinoma cells (Colon 26 line) transfected with nm23-R2/rat nucleoside diphosphate kinase alpha isoform.
Regulation of cellular functions by nucleoside diphosphate kinases in mammals.
Semiquantitative immunoblot analysis of nm23-H1 and -H2 isoforms in adenocarcinomas of the lung: prognostic significance.
Targeting SET/I(2)PP2A oncoprotein functions as a multi-pathway strategy for cancer therapy.
[Expression and clinical significance of nm23-H1 and CD44v6 in non-small cell lung cancer].
[Relationship between nm23-H1 expression and lymph node metastasis and prognosis in cervical cancer]
Adenocarcinoma of Lung
[Effect of Nm23-H1 Nuclear Localization on Proliferation of ?Human Lung Adenocarcinoma Cell Line A549].
[Establishment of the cell line that human lung adenocarcinoma can stably express luciferase which is absent of nm23-H1 expression and detecting its luminescence?in vitro and in vivo].
Adenocarcinoma, Clear Cell
Estrogen and progestin regulate metastasis through the PI3K/AKT pathway in human ovarian cancer.
Adenocarcinoma, Follicular
Analysis of nm23-H1 protein immunoreactivity in follicular thyroid tumors.
nm23-H1 immunoreactivity as a prognostic factor in differentiated thyroid carcinoma.
[Prognostic significance of selected oncogene and suppressor gene expression in follicular thyroid carcinoma]
Adenocarcinoma, Papillary
[Expression of CD44V6 and nm23-H1 in thyroid papillary adenocarcinoma and lymph node metastasis]
Adenoma
Analysis of nm23-H1 protein immunoreactivity in follicular thyroid tumors.
nm23-H1 protein immunoreactivity in cancers of the gallbladder, extrahepatic bile ducts and ampulla of Vater.
Adenomatous Polyposis Coli
Histological groups of human postpubertal testicular germ cell tumours harbour different genetic alterations.
Somatic allelic loss at the DCC, APC, nm23-H1 and p53 tumor suppressor gene loci in human prostatic carcinoma.
Adenomatous Polyps
Survey of molecular profiling during human colon cancer development and progression by immunohistochemical staining on tissue microarray.
Alzheimer Disease
Human brain nucleoside diphosphate kinase activity is decreased in Alzheimer's disease and Down syndrome.
Anemia, Aplastic
Elevated plasma level of differentiation inhibitory factor nm23-H1 protein correlates with risk factors for myelodysplastic syndrome.
Anemia, Refractory
Elevated plasma level of differentiation inhibitory factor nm23-H1 protein correlates with risk factors for myelodysplastic syndrome.
Arrhythmogenic Right Ventricular Dysplasia
Nucleoside Diphosphate Kinase B Contributes to Arrhythmogenesis in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes from a Patient with Arrhythmogenic Right Ventricular Cardiomyopathy.
Arthritis, Rheumatoid
Constitutive expression of c-fos and c-jun, overexpression of ets-2, and reduced expression of metastasis suppressor gene nm23-H1 in rheumatoid arthritis.
Asthma
A shotgun proteomic approach reveals novel potential salivary protein biomarkers for asthma.
Astrocytoma
Analysis of the antibody repertoire of astrocytoma patients against antigens expressed by gliomas.
Gene expression profiling of low-grade diffuse astrocytomas by cDNA arrays.
Transcription analysis of TIMP-1 and NM23-H1 genes in glioma cell invasion.
Atherosclerosis
NM23-H2, an estrogen receptor beta-associated protein, shows diminished expression with progression of atherosclerosis.
Nucleoside diphosphate kinase B-activated intermediate conductance potassium channels are critical for neointima formation in mouse carotid arteries.
Autoimmune Diseases
Nucleoside diphosphate kinase B knockout mice have impaired activation of the K+ channel KCa3.1 resulting in defective T cell activation.
Barrett Esophagus
Comparative proteomics analysis of Barrett metaplasia and esophageal adenocarcinoma using two-dimensional liquid mass mapping.
Breast Diseases
Evaluation of the expression levels of nm23-H1 mRNA in primary breast cancer, benign breast disease, axillary lymph nodes and normal breast tissue.
Breast Neoplasms
A monoclonal antibody driven biodiagnostic system for the quantitative screening of breast cancer.
A novel function for the nm23-H1 gene: overexpression in human breast carcinoma cells leads to the formation of basement membrane and growth arrest.
Activation of antimetastatic Nm23-H1 gene expression by estrogen and its alpha-receptor.
Activation of Nm23-H1 to suppress breast cancer metastasis via redox regulation.
Amplification and overexpression of PRUNE in human sarcomas and breast carcinomas-a possible mechanism for altering the nm23-H1 activity.
Analysis of nm23-H1 expression in breast cancer. Correlation with p53 expression and clinicopathologic findings.
Analysis of oncogenes and tumor suppressor genes in human breast cancer.
Anti-tumor peptide SA12 inhibits metastasis of MDA-MB-231 and MCF-7 breast cancer cells via increasing expression of the tumor metastasis suppressor genes, CDH1, nm23-H1 and BRMS1.
Bacillus anthracis' PA63 Delivers the Tumor Metastasis Suppressor Protein NDPK-A/NME1 into Breast Cancer Cells.
Cell cycle effects and control of gene expression by resveratrol in human breast carcinoma cell lines with different metastatic potentials.
Clinical-translational approaches to the Nm23-H1 metastasis suppressor.
Correlation of MDR-1, nm23-H1 and H Sema E gene expression with histopathological findings and clinical outcome in ovarian and breast cancer patients.
Correlation of NM23-H1 cytoplasmic expression with metastatic stage in human prostate cancer tissue.
Correlation of nm23-H1 gene expression with clinical outcome in patients with advanced breast cancer.
CTCF and EGR1 suppress breast cancer cell migration through transcriptional control of Nm23-H1.
Dexamethasone and medroxyprogesterone acetate elevate Nm23-H1 metastasis suppressor gene expression in metastatic human breast carcinoma cells: new uses for old compounds.
Elevated nm23 protein expression is correlated with diminished progression-free survival in patients with epithelial ovarian carcinoma.
Elevation of breast carcinoma Nm23-H1 metastasis suppressor gene expression and reduced motility by DNA methylation inhibition.
Epstein-Barr virus nuclear protein EBNA-3C interacts with the human metastatic suppressor Nm23-H1: a molecular link to cancer metastasis.
Epstein-Barr virus protein can upregulate cyclo-oxygenase-2 expression through association with the suppressor of metastasis Nm23-H1.
ER, PgR, HER-2, Ki-67, topoisomerase II?, and nm23-H1 proteins expression as predictors of pathological complete response to neoadjuvant chemotherapy for locally advanced breast cancer.
Evaluation of ER, PgR, HER-2, Ki-67, cyclin D1, and nm23-H1 as predictors of pathological complete response to neoadjuvant chemotherapy for locally advanced breast cancer.
Evaluation of the expression levels of nm23-H1 mRNA in primary breast cancer, benign breast disease, axillary lymph nodes and normal breast tissue.
Expression of alpha V integrin is modulated by Epstein-Barr virus nuclear antigen 3C and the metastasis suppressor Nm23-H1 through interaction with the GATA-1 and Sp1 transcription factors.
Expression of c-myc, erbB-2, p53 and nm23-H1 gene product in benign and malignant breast lesions: coexpression and correlation with clinicopathologic parameters.
Expression of nm23-H1 gene and Sialyl Lewis X antigen in breast cancer.
Expression patterns of ER, HER2, and NM23-H1 in breast cancer patients with different menopausal status: correlations with metastasis.
Extracellular Vesicle-Mediated Purinergic Signaling Contributes to Host Microenvironment Plasticity and Metastasis in Triple Negative Breast Cancer.
Histological groups of human postpubertal testicular germ cell tumours harbour different genetic alterations.
Identification and characterization of the promoter for the human metastasis suppressor gene nm23-H1.
Identification of a second human nm23 gene, nm23-H2.
Increased expression of h-prune is associated with tumor progression and poor survival in gastric cancer.
Increased nm23-H1 and nm23-H2 messenger RNA expression and absence of mutations in colon carcinomas of low and high metastatic potential.
Increased sensitivity to cisplatin by nm23-transfected tumor cell lines.
Inhibition of Nm23H2 gene product (NDPK-B) by angiostatin, polyphenols and nucleoside analogs.
Interaction of the Tumor Metastasis Suppressor Nonmetastatic Protein 23 Homologue H1 and Estrogen Receptor {alpha} Alters Estrogen-Responsive Gene Expression.
Isolation and characterization of the human genomic locus coding for the putative metastasis control gene nm23-H1.
Medroxyprogesterone acetate elevation of Nm23-H1 metastasis suppressor expression in hormone receptor-negative breast cancer.
Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance.
Microsatellite instabilities at five chromosomes in primary breast tumors.
miR-146a promoted breast cancer proliferation and invasion by regulating NM23-H1.
MMTV-associated transcription factor binding sites increase nm23-H1 metastasis suppressor gene expression in human breast carcinoma cell lines.
Multiple mechanisms underlie metastasis suppressor function of NM23-H1 in melanoma.
Nm-23, c-erbB-2, and progesterone receptor expression in invasive breast cancer: correlation with clinicopathologic parameters.
Nm23 and breast cancer metastasis.
Nm23 and tumour metastasis: basic and translational advances.
NM23 downregulation and lysophosphatidic acid receptor EDG2/lpa1 upregulation during myeloid differentiation of human leukemia cells.
NM23-H1 and NM23-H2 repress transcriptional activities of nuclease-hypersensitive elements in the platelet-derived growth factor-A promoter.
Nm23-H1 Binds to Gelsolin and Inactivates Its Actin-Severing Capacity to Promote Tumor Cell Motility and Metastasis.
NM23-H1 immunostaining is inversely associated with tumour staging but not overall survival or disease recurrence in colorectal carcinomas.
Nm23-h1 indirectly promotes the survival of acute myeloid leukemia blast cells by binding to more mature components of the leukemic clone.
Nm23-H1 metastasis suppressor expression level influences the binding properties, stability, and function of the kinase suppressor of Ras1 (KSR1) Erk scaffold in breast carcinoma cells.
Nm23-H1 metastasis suppressor phosphorylation of kinase suppressor of Ras via a histidine protein kinase pathway.
Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1.
nm23-H1 protein immunohistochemical expression in human breast cancer.
Nm23-H1 suppresses metastasis by inhibiting expression of the lysophosphatidic acid receptor EDG2.
Nm23-H1 suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2.
Nm23-H1/nucleoside diphosphate kinase as a key molecule in breast tumor angiogenesis.
Nm23-transfected MDA-MB-435 human breast carcinoma cells form tumors with altered phospholipid metabolism and pH: a 31P nuclear magnetic resonance study in vivo and in vitro.
Nucleoside diphosphate kinase A/nm23-H1 promotes metastasis of NB69-derived human neuroblastoma.
Overexpression of h-prune in breast cancer is correlated with advanced disease status.
Phosphorylation of nm23-H1 by CKI induces its complex formation with h-prune and promotes cell motility.
Prognostic significance of Nm23/NDPK expression in breast carcinoma, assessed on 10-year follow-up by automated and quantitative immunocytochemical assays.
Protein-protein interactions: a mechanism regulating the anti-metastatic properties of Nm23-H1.
Purinergic regulation of angiogenesis by human breast carcinoma-secreted nucleoside diphosphate kinase.
Purinergic regulation of vascular endothelial growth factor signaling in angiogenesis.
Reduced expression of nm23-H1, but not of nm23-H2, is concordant with the frequency of lymph-node metastasis of human breast cancer.
Relationship of nm23 to proteolytic factors, proliferation and motility in breast cancer tissues and cell lines.
Separating favorable from unfavorable prognostic markers in breast cancer: the role of E-cadherin.
Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells.
Site-directed mutation of Nm23-H1. Mutations lacking motility suppressive capacity upon transfection are deficient in histidine-dependent protein phosphotransferase pathways in vitro.
Suppression of MDA-MB-435 breast carcinoma cell metastasis following the introduction of human chromosome 11.
The Epstein Barr nuclear antigen EBNA3C regulates transcription, cell transformation and cell migration.
The metastatic suppressor Nm23-H1 interacts with EBNA3C at sequences located between the glutamine- and proline-rich domains and can cooperate in activation of transcription.
The potential roles of nm23 in cancer metastasis and cellular differentiation.
The suppressor of metastasis Nm23-H1 interacts with the Cdc42 Rho family member and the pleckstrin homology domain of oncoprotein Dbl-1 to suppress cell migration.
Toponostics of invasive ductal breast carcinoma: combination of spatial protein expression imaging and quantitative proteome signature analysis.
Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: effects on tumor metastatic potential, colonization and enzymatic activity.
Two-component kinase-like activity of nm23 correlates with its motility-suppressing activity.
Understanding h-prune biology in the fight against cancer.
Wild-type NM23-H1, but not its S120 mutants, suppresses desensitization of muscarinic potassium current.
YNK1, the yeast homolog of human metastasis suppressor NM23, is required for repair of UV radiation- and etoposide-induced DNA damage.
[Expression of sialylated carbohydrate antigens and nm23-H1 gene in prognosis of breast cancer]
[Expressions of vascular endothelial growth factor and nm23-H1 gene and their relation to the prognosis of breast cancer in young women.]
[Low expression of nm23-H1 mRNA and its protein in breast cancer]
[The relationship between prognosis, metastasis and microvessel quantity in invasive breast carcinoma]
[Ultrastructural immunocytochemical localization of diphosphate kinase/Nm23 in human cancer cells]
Burkitt Lymphoma
Epstein-Barr virus nuclear protein EBNA-3C interacts with the human metastatic suppressor Nm23-H1: a molecular link to cancer metastasis.
Epstein-Barr virus protein can upregulate cyclo-oxygenase-2 expression through association with the suppressor of metastasis Nm23-H1.
Nm23-H1 can induce cell cycle arrest and apoptosis in B cells.
The Epstein Barr nuclear antigen EBNA3C regulates transcription, cell transformation and cell migration.
Carcinogenesis
Concurrent high expression of human telomerase reverse transcriptase and human nonmetastatic clone 23 in high-grade squamous intraepithelial neoplasia and squamous cell carcinoma of uterine cervix.
Crystallization and preliminary X-ray diffraction studies of nucleoside diphosphate kinase from Dictyostelium discoideum.
Diagnostic and biological determinants in undifferentiated and poorly differentiated ovarian carcinomas.
Estrogen and progestin regulate metastasis through the PI3K/AKT pathway in human ovarian cancer.
Expression of p16, nm23-H1, E-cadherin, and CD44 gene products and their significance in nasopharyngeal carcinoma.
Immunohistochemical analysis of nm23-H1 expression in human cervical lesions.
Immunoreactivity of nm23-H1 protein in renal cell carcinoma.
Increased levels of nm23 H1/nucleoside diphosphate kinase A mRNA associated with adenocarcinoma of the prostate.
Irradiation of rainbow trout at early life stages results in a proteomic legacy in adult gills. Part A; proteomic responses in the irradiated fish and in non-irradiated bystander fish.
Irradiation of rainbow trout at early life stages results in a proteomic legacy in adult gills. Part B; the effect of a second radiation dose, after one year, on the proteomic responses in the irradiated and non-irradiated bystander fish.
Janus-faces of NME-oncoprotein interactions.
Mutations at the dimer interface and surface residues of Nm23-H1 metastasis suppressor affect its expression and function.
nm23-H1 gene driven by hTERT promoter induces inhibition of invasive phenotype and metastasis of lung cancer xenograft in mice.
Nm23-H1 immunohistochemical expression in multisteps of cervical carcinogenesis.
NM23-H1 immunostaining is inversely associated with tumour staging but not overall survival or disease recurrence in colorectal carcinomas.
nm23-H1 protein expression in anal canal carcinoma: does it correlate with prognosis?
Nm23-H1: a metastasis-associated gene.
Peptidic determinants and structural model of human NDP kinase B (Nm23-H2) bound to single-stranded DNA.
Reappraisal of the role of NM23-H1 in colorectal cancers.
Regulators affecting the metastasis suppressor activity of Nm23-H1.
Regulatory functions of Nm23-H2 in tumorigenesis: insights from biochemical to clinical perspectives.
RGS19 upregulates Nm23-H1/2 metastasis suppressors by transcriptional activation via the cAMP/PKA/CREB pathway.
Suppressive role of the metastasis-related nm23-H1 gene in human ovarian carcinomas: association of high messenger RNA expression with lack of lymph node metastasis.
The metastasis suppressor NM23-H1 possesses 3'-5' exonuclease activity.
The multiple regulation of metastasis suppressor NM23-H1 in cancer.
The N-myc and c-myc downstream pathways include the chromosome 17q genes nm23-H1 and nm23-H2.
The role of nm23-H1 in the progression of transitional cell bladder cancer.
X-ray structure of nucleoside diphosphate kinase.
[Expression and implication of CD44 and nm23-H1 proteins in laryngeal carcinoma]
[Mutation and expression of nm23-H1 and CD44 gene in prostate cancers]
Carcinoid Tumor
High levels of nm23-H1 and nm23-H2 messenger RNA in human squamous-cell lung carcinoma are associated with poor differentiation and advanced tumor stages.
Overexpression of nucleoside diphosphate/kinase A/nm23-H1 protein in human lung tumors: association with tumor progression in squamous carcinoma.
Carcinoma
A high nuclear nm23-H1 expression is associated with a better prognosis in elderly patients with laryngeal carcinoma.
A prognostic role for Nm23-H1 in laryngeal carcinoma treated with postoperative radiotherapy: an introductory investigation.
A review of molecular pathological markers in vulvar carcinoma: lack of application in clinical practice.
Alteration in gene expression profile by full-length hepatitis B virus genome.
Altered expression of nm23-H1 and c-erbB-2 proteins have prognostic significance in adenocarcinoma but not in squamous cell carcinoma of the uterine cervix.
Analysis of nm23 gene expressions in human bladder and renal cancers.
Analysis of nm23-H1 protein immunoreactivity in follicular thyroid tumors.
Association between nm23-H1 expression, proliferation and apoptosis in non-small cell lung carcinomas.
Association between Nm23-H1 gene expression and metastasis of ovarian carcinoma.
Clinical significance of high nm23-H1 expression in intraepithelial neoplasia and early-stage squamous cell carcinoma of the uterine cervix.
Clinicopathological features and prognostic significance of nucleoside diphosphate kinase/nm23 gene product in human pancreatic exocrine neoplasms.
Concurrent high expression of human telomerase reverse transcriptase and human nonmetastatic clone 23 in high-grade squamous intraepithelial neoplasia and squamous cell carcinoma of uterine cervix.
Correlation between nm23-H1 overexpression and clinicopathological variables in human anal canal carcinoma.
Different expression of nm23-H1 and nm23-H2 protein with proliferative activities in various sizes of human renal cell carcinoma.
Down-regulated nucleoside diphosphate kinase nm23-H1 expression is unrelated to high-risk human papillomavirus but associated with progression of cervical intraepithelial neoplasia and unfavourable prognosis in cervical cancer.
Downregulation of intracellular nm23-H1 prevents cisplatin-induced DNA damage in oesophageal cancer cells: possible association with Na(+), K(+)-ATPase.
Downstream targets of Nm23-H1: gene expression profiling of CAL 27 cells using DNA microarray.
Elderly patients at higher risk of laryngeal carcinoma recurrence could be identified by a panel of two biomarkers (nm23-H1 and CD105) and pN+ status.
Estrogen and progestin regulate metastasis through the PI3K/AKT pathway in human ovarian cancer.
Evaluation of the expression levels of nm23-H1 mRNA in primary breast cancer, benign breast disease, axillary lymph nodes and normal breast tissue.
Expression of c-myc, erbB-2, p53 and nm23-H1 gene product in benign and malignant breast lesions: coexpression and correlation with clinicopathologic parameters.
Expression of metastasis-related nm23-H1 and nm23-H2 genes in ovarian carcinomas: correlation with clinicopathology, EGFR, c-erbB-2, and c-erbB-3 genes, and sex steroid receptor expression.
Expression of nm23 in gastric carcinoma: association with tumor progression and poor prognosis.
Expression of nm23-H1 and nm23-H2 proteins in prostate carcinoma.
Expression of nm23-h1 gene in squamous-cell carcinoma of the cervix correlates with 5-year survival.
Expression of nm23-H1 gene product in esophageal squamous cell carcinoma and its association with vessel invasion and survival.
Expression of nm23-H1 gene product in sarcomatous cancer cells of renal cell carcinoma: correlation with tumor stage and expression of matrix metalloproteinase-2, matrix metalloproteinase-9, sialyl Lewis X, and c-erbB-2.
Expression of nm23-H1 gene product in thyroid, ovary, and breast cancers.
Expression of nm23-H1 in transitional cell carcinoma of the upper urinary tract.
Expression of the nm23 homologues nm23-H4, nm23-H6, and nm23-H7 in human gastric and colon cancer.
Expression of the nucleoside diphosphate kinase in human skin cancers: an immunohistochemical study.
Gene expression profiling of Nm23-H2 overexpressing CAL 27 cells using DNA microarray.
Gene profiling in Pap-cell smears of high-risk human papillomavirus-positive squamous cervical carcinoma.
H-ras and Nm23-H1 gene expression and proteolytic activity in squamous cell carcinoma of the uterine cervix.
High frequency of concomitant nm23-H1 and E-cadherin transcriptional inactivation in primary non-inheriting colorectal carcinomas.
High levels of nm23-H1 and nm23-H2 messenger RNA in human squamous-cell lung carcinoma are associated with poor differentiation and advanced tumor stages.
Identification of genes (SPON2 and C20orf2) differentially expressed between cancerous and noncancerous lung cells by mRNA differential display.
Immunoexpression of Claudin-1 and Nm23-H1 in Metastatic and Nonmetastatic Lower Lip Squamous-cell Carcinoma.
Immunohistochemical analysis of nm23-H1 expression in human cervical lesions.
Immunohistochemical analysis of nucleoside diphosphate kinases in oral squamous cell carcinomas.
Immunohistochemical evaluation of nm23-H1 gene product in transitional cell carcinoma of the bladder.
Immunohistologic detection of nm23-H1 protein in squamous cell carcinoma of the vulva.
Immunoreactivity of nm23-H1 protein in renal cell carcinoma.
Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells.
Increased activity of nm23-H1 gene in squamous cell carcinoma of the head and neck is associated with advanced disease and poor prognosis.
Increased nm23-H1 and nm23-H2 messenger RNA expression and absence of mutations in colon carcinomas of low and high metastatic potential.
Indications for postoperative RT in laryngeal carcinoma: A panel of tumor tissue markers for predicting locoregional recurrence in surgically-treated carcinoma. A pilot study.
Inhibition of colonization and cell-matrix adhesion after nm23-H1 transfection of human prostate carcinoma cells.
Inhibitory activity of nm23-H1 on invasion and colonization of human prostate carcinoma cells is not mediated by its NDP kinase activity.
Loss of heterozygosity of the nm23-H1 gene in human renal cell carcinomas.
Mutation of the nm23 gene, loss of heterozygosity at the nm23 locus and K-ras mutation in ovarian carcinoma: correlation with tumour progression and nm23 gene expression.
Nm-23, c-erbB-2, and progesterone receptor expression in invasive breast cancer: correlation with clinicopathologic parameters.
nm23-H1 expression defines a high-risk subpopulation of patients with early-stage epithelial ovarian carcinoma.
nm23-H1 expression in salivary adenoid cystic carcinoma in relation to metastasis and survival.
nm23-H1 Expression in Squamous Cell Carcinoma of the Head and Neck.
NM23-H1 expression of head and neck squamous cell carcinoma in association with the response to cisplatin treatment.
NM23-H1 Expression of Head and Neck Squamous Cell Carcinoma in Association With the Response to Irradiation.
Nm23-H1 expression of metastatic tumors in the lymph nodes is a prognostic indicator of oral squamous cell carcinoma.
nm23-H1 gene expression in ovarian tumors--a potential tumor marker.
Nm23-H1 immunohistochemical expression in multisteps of cervical carcinogenesis.
nm23-H1 immunoreactivity as a prognostic factor in differentiated thyroid carcinoma.
Nm23-H1 nuclear expression is associated with a more favourable prognosis in laryngeal carcinoma: univariate and multivariate analysis.
Nm23-H1 promotes adhesion of CAL 27 cells in vitro.
nm23-H1 protein expression in anal canal carcinoma: does it correlate with prognosis?
nm23-H1 protein immunoreactivity in cancers of the gallbladder, extrahepatic bile ducts and ampulla of Vater.
nm23-H1 protein immunoreactivity in intraepithelial neoplasia and invasive squamous cell carcinoma of the uterine cervix.
nm23-H1 protein immunoreactivity in laryngeal carcinoma.
Nm23-H1 protein, DNA-ploidy and S-phase fraction in relation to overall survival and disease free survival in transitional cell carcinoma of the bladder.
nm23-H1 reduces in vitro cell migration and the liver metastatic potential of colon cancer cells by regulating myosin light chain phosphorylation.
nm23-H1 suppresses invasion of oral squamous cell carcinoma-derived cell lines without modifying matrix metalloproteinase-2 and matrix metalloproteinase-9 expression.
Nuclear expression of onco-suppressors nm23-H1 and maspin are associated with lower recurrence rate in laryngeal carcinoma.
Nuclear localization of Nm23-H1 in head and neck squamous cell carcinoma is associated with radiation resistance.
Nuclear nonmetastatic protein 23-H1 expression and epithelial-mesenchymal transition in laryngeal carcinoma: A pilot investigation.
Overexpression of nm23-H4 RNA in colorectal and renal tumours.
Overexpression of nucleoside diphosphate/kinase A/nm23-H1 protein in human lung tumors: association with tumor progression in squamous carcinoma.
Point mutations affecting the oligomeric structure of Nm23-H1 abrogates its inhibitory activity on colonization and invasion of prostate cancer cells.
Prediction of lymph node metastasis based on p53 and nm23-H1 expression in muscle invasive grade III transitional cell carcinoma of bladder.
Preferential reduction of nm23-H1 gene product in metastatic tissues from papillary and follicular carcinomas of the thyroid.
Prevalence of nucleoside diphosphate kinase autophosphorylation in human colon carcinoma versus normal colon homogenates.
Prognostic significance of nm23-H1 expression in esophageal squamous cell carcinoma.
Prognostic significance of nm23-H1 expression in oral squamous cell carcinoma.
Prognostic value of nm23 protein expression in renal cell carcinomas.
Regulation of cellular functions by nucleoside diphosphate kinases in mammals.
Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells.
Somatic allelic deletion of nm23 in human cancer.
Somatic allelic loss at the DCC, APC, nm23-H1 and p53 tumor suppressor gene loci in human prostatic carcinoma.
Squamous cell lung carcinomas: the role of nm23-H1 gene.
Study on the metastatic mechanisms of human giant-cell lung carcinoma comparison between the strains C and D.
Suppressive role of the metastasis-related nm23-H1 gene in human ovarian carcinomas: association of high messenger RNA expression with lack of lymph node metastasis.
The abundance of NM23-H1 mRNA is related with in situ microenvironment and intrahepatic metastasis in hepato-cellular carcinoma.
The association between nm23-H1 expression and survival in patients with esophageal squamous cell carcinoma.
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
The nm23-H1 gene as a predictor of sensitivity to chemotherapeutic agents in oesophageal squamous cell carcinoma.
Value of ezrin, maspin and nm23-H1 protein expressions in predicting outcome of patients with head and neck squamous-cell carcinoma treated with radical radiotherapy.
Widely targeted metabolomic analyses unveil the metabolic variations after stable knock-down of NME4 in esophageal squamous cell carcinoma cells.
[Correlation of multiple gene changes with malignant phenotype of human gastric carcinoma]
[Effects of Fuzheng Yiliu Granule on expression of CD44v6 and nm23-H1 in esophageal carcinoma treated with radiotherapy]
[Effects of transfection of nm23-H1 gene on ?-catenin expression in human high-metastatic large cell lung cancer cell line L9981.]
[Establishment and their biological characteristics of clonal cell subpopulations (NL9980 and L9981) from a human lung large cell carcinoma cell line (WCQH-9801).]
[Expression and clinical significance of nm23-H1 and CD44v6 in non-small cell lung cancer].
[Expression and clinical significance of nm23-H1, Fas and FasL in colorectal carcinoma tissues]
[Expression and implication of CD44 and nm23-H1 proteins in laryngeal carcinoma]
[Expression clinical significance of nm23-H1 and vessel endothelium growth factor protein in nasopharyngeal carcinoma]
[Expression of CD44v and nm23-H1 proteins in laryngeal carcinoma and its correlation with clinical significance]
[Expression of ERK and nm23-H1 in tongue squamous cell carcinoma and its relation with invasion and metastasis].
[Expression of metastasis suppressor gene nm23-H1 in oral squamous cell carcinoma and its relation to tumor prognosis]
[Expression of nm23-H1 gene in oral squamous cell carcinoma and its relation to tumor metastasis]
[Expression of vascular endothelial growth factor, vascular endothelial growth factor receptor-3 and nm23-H1 in oral squamous cell carcinoma]
[Feasibility of cationic lipid mediated nm23-h1 plasmid transfecting adnoid cystic carcinoma in vivo]
[In vitro and in vivo study on proliferation of adnoid cystic carcinoma cell lines after nm23-h1. Introduction]
[mRNA expression of metastasis-suppressor gene nm23 in carcinoma of buccal mucosa I. Northern blotting study]
[mRNA expression of metastasis-suppressor gene nm23 in carcinoma of buccal mucosa. II. Quantitative reverse transcription PCR amplification]
[Mutation and expression of nm23-H1 and CD44 gene in prostate cancers]
[Mutational analysis of nm23-H1 gene in human lung cancer by polymerase chain reaction-single strand conformation polymorphism.]
[nm23 expression and its correlation with lung metastasis in human salivary adenoid cystic carcinoma]
[nm23-H1 gene inhibits lung cancer cell invasion through down-regulation of PKC signal pathway]
[nm23-H1 protein expression and its clinical significance in human laryngeal carcinoma]
[Northern blot analysis of nm23 gene expression in human lung cancer]
[Pathological study on the expression of cell adhesion molecules and metastasis suppressor gene in thyroid follicular carcinoma and papillary carcinoma]
[Relationship between nm23-H1 expression and lymph node metastasis and prognosis in cervical cancer]
[Study on expression of nm23-H1 gene in laryngeal cancer tissues]
[Study on expression of nm23-H1 protein/NDPK-A in laryngeal carcinoma]
[The correlation between lung cancer lymph node metastasis and nm23-H1 gene mutation, mRNA expression]
[The mechanism and influence on the biological behavior of human high-metastatic large cell lung cancer cell lines with transfection of nm23-H1 gene.]
[The significance of nm23 gene expression in embryonic tissues and lung cancer tissues.]
Carcinoma in Situ
Increased activity of nm23-H1 gene in squamous cell carcinoma of the head and neck is associated with advanced disease and poor prognosis.
Carcinoma, Adenoid Cystic
nm23-H1 expression in salivary adenoid cystic carcinoma in relation to metastasis and survival.
[nm23 expression and its correlation with lung metastasis in human salivary adenoid cystic carcinoma]
Carcinoma, Adenosquamous
Altered expression of nm23-H1 and c-erbB-2 proteins have prognostic significance in adenocarcinoma but not in squamous cell carcinoma of the uterine cervix.
Carcinoma, Basal Cell
Expression of the nucleoside diphosphate kinase in human skin cancers: an immunohistochemical study.
Carcinoma, Ductal
Immunohistochemical demonstration of the nm23-H1 gene product in human malignant melanoma and Spitz nevi.
Nm-23, c-erbB-2, and progesterone receptor expression in invasive breast cancer: correlation with clinicopathologic parameters.
Carcinoma, Endometrioid
Observations on tumor and metastatic suppressor gene status in endometrial carcinoma with particular emphasis on p53.
Carcinoma, Hepatocellular
Expression and significance of heparanase and nm23-H1 in hepatocellular carcinoma.
Expression in human hepatocellular carcinoma of nucleoside diphosphate kinase, a homologue of the nm23 gene product.
Expression of human nm23-H1 and nm23-H2 proteins in hepatocellular carcinoma.
Expressions of Nucleoside Diphosphate Kinase (nm23) in Tumor Tissues are Related with Metastasis and Length of Survival of Patients with Hepatocellular Carcinoma.
Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells.
Increased UDP kinase activity in rat and human hepatomas.
Intracellular levels of S-adenosylhomocysteine but not homocysteine are highly correlated to the expression of nm23-H1 and the level of 5-methyldeoxycytidine in human hepatoma cells with different invasion activities.
Isolation and characterization of the human genomic locus coding for the putative metastasis control gene nm23-H1.
Lycopene inhibits cell migration and invasion and upregulates Nm23-H1 in a highly invasive hepatocarcinoma, SK-Hep-1 cells.
NM23-H1 and NM23-H2 messenger RNA abundance in human hepatocellular carcinoma.
nm23-H1 expression and disease recurrence after surgical resection of small hepatocellular carcinoma.
Nm23-H1 expression in intrahepatic or extrahepatic metastases of hepatocellular carcinoma.
Nm23-H1 suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2.
Pro-oncogenic potential of NM23-H2 in hepatocellular carcinoma.
Reduced expression and rare genomic alteration of nm23-H1 in human hepatocellular carcinoma and hepatoma cell lines.
Relationship between expression of CD44v6 and nm23-H1 and tumor invasion and metastasis in hepatocellular carcinoma.
Telomerase activity and Nm23-H2 protein expression in hepatocellular carcinoma.
Transcatheter arterial chemoembolization enhances expression of Nm23-H1 and TIMP-2 in the tumor tissue of patients with hepatocellular carcinoma.
Up-regulation of nm23/NDP kinase expression in regenerating hepatocytes.
[Alteration of genomic structure and/or expression of cancer associated genes in hepatocellular carcinoma]
[Expression of metastasis suppressor gene nm23 in human hepatocellular carcinoma]
[Relationships between intrahepatic metastasis of hepatocellular carcinoma and in situ microenvironment, and the abundance of nm23-H1 H-ras mRNA]
[The expression and significance of heparanase and nm23-H1 in hepatocellular carcinoma]
[The relationship between nm23-H1 loss of heterozygosity and metastasis in hepatocellular carcinoma]
Carcinoma, Large Cell
[Establishment and their biological characteristics of clonal cell subpopulations (NL9980 and L9981) from a human lung large cell carcinoma cell line (WCQH-9801).]
Carcinoma, Medullary
Expression of nm23-H1 gene product in thyroid, ovary, and breast cancers.
Preferential reduction of nm23-H1 gene product in metastatic tissues from papillary and follicular carcinomas of the thyroid.
Carcinoma, Neuroendocrine
[Expression and significance of bcl-2, bax, P53 in neuroendocrine carcinomas of the lung.]
Carcinoma, Non-Small-Cell Lung
Co-downregulation of PTEN, KAI-1, and nm23-H1 tumor/metastasis suppressor proteins in non-small cell lung cancer.
High levels of nm23-H1 and nm23-H2 messenger RNA in human squamous-cell lung carcinoma are associated with poor differentiation and advanced tumor stages.
Immunohistochemical analysis of nm23-H1 in stage I non-small cell lung cancer: a useful marker in prediction of metastases.
nm23-H1 gene driven by hTERT promoter induces inhibition of invasive phenotype and metastasis of lung cancer xenograft in mice.
Nm23-H1 inhibits hypoxia induced epithelial-mesenchymal transition and stemness in non-small cell lung cancer cells.
Prognostic impact of nm23-H1 and PCNA expression in pathologic stage I non-small cell lung cancer.
Prognostic significance of expression of nm23-H1 and focal adhesion kinase in non-small cell lung cancer.
Transcriptional factor FOXO3 negatively regulates the expression of nm23-H1 in non-small cell lung cancer.
Transfection of nm23-H1 increased expression of beta-Catenin, E-Cadherin and TIMP-1 and decreased the expression of MMP-2, CD44v6 and VEGF and inhibited the metastatic potential of human non-small cell lung cancer cell line L9981.
[Expression and clinical significance of nm23-H1 and CD44v6 in non-small cell lung cancer].
[Expression and significance of PTEN and nm23-H1 in the metastasis of non-small cell lung cancer.]
[The correlation between lung cancer lymph node metastasis and nm23-H1 gene mutation, mRNA expression]
Carcinoma, Ovarian Epithelial
Expression of antimetastatic gene nm23-H1 in epithelial ovarian cancer.
nm23-H1 expression defines a high-risk subpopulation of patients with early-stage epithelial ovarian carcinoma.
[Influence of estrogen and progestin on nm23-H1 expression in epithelial ovarian cancer cell lines via activation of phosphorylation signaling]
Carcinoma, Papillary
Expression of nm23-H1 and COX-2 in thyroid papillary carcinoma and microcarcinoma.
Expression of nm23-H1 gene product in thyroid, ovary, and breast cancers.
nm23-H1 immunoreactivity as a prognostic factor in differentiated thyroid carcinoma.
Preferential reduction of nm23-H1 gene product in metastatic tissues from papillary and follicular carcinomas of the thyroid.
[Pathological study on the expression of cell adhesion molecules and metastasis suppressor gene in thyroid follicular carcinoma and papillary carcinoma]
Carcinoma, Renal Cell
Analysis of nm23 gene expressions in human bladder and renal cancers.
Different expression of nm23-H1 and nm23-H2 protein with proliferative activities in various sizes of human renal cell carcinoma.
Expression of nm23-H1 gene product in sarcomatous cancer cells of renal cell carcinoma: correlation with tumor stage and expression of matrix metalloproteinase-2, matrix metalloproteinase-9, sialyl Lewis X, and c-erbB-2.
Immunoreactivity of nm23-H1 protein in renal cell carcinoma.
Loss of heterozygosity of the nm23-H1 gene in human renal cell carcinomas.
MDM2 interacts with NME2 (non-metastatic cells 2, protein) and suppresses the ability of NME2 to negatively regulate cell motility.
Overexpression of nm23-H4 RNA in colorectal and renal tumours.
Prognostic value of nm23 protein expression in renal cell carcinomas.
Carcinoma, Squamous Cell
Altered expression of nm23-H1 and c-erbB-2 proteins have prognostic significance in adenocarcinoma but not in squamous cell carcinoma of the uterine cervix.
Clinical significance of high nm23-H1 expression in intraepithelial neoplasia and early-stage squamous cell carcinoma of the uterine cervix.
Concurrent high expression of human telomerase reverse transcriptase and human nonmetastatic clone 23 in high-grade squamous intraepithelial neoplasia and squamous cell carcinoma of uterine cervix.
Down-regulated nucleoside diphosphate kinase nm23-H1 expression is unrelated to high-risk human papillomavirus but associated with progression of cervical intraepithelial neoplasia and unfavourable prognosis in cervical cancer.
Expression of nm23-h1 gene in squamous-cell carcinoma of the cervix correlates with 5-year survival.
Expression of the nucleoside diphosphate kinase in human skin cancers: an immunohistochemical study.
Gene expression profiling of Nm23-H2 overexpressing CAL 27 cells using DNA microarray.
Gene profiling in Pap-cell smears of high-risk human papillomavirus-positive squamous cervical carcinoma.
H-ras and Nm23-H1 gene expression and proteolytic activity in squamous cell carcinoma of the uterine cervix.
Immunohistologic detection of nm23-H1 protein in squamous cell carcinoma of the vulva.
Increased activity of nm23-H1 gene in squamous cell carcinoma of the head and neck is associated with advanced disease and poor prognosis.
nm23-H1 Expression in Squamous Cell Carcinoma of the Head and Neck.
NM23-H1 expression of head and neck squamous cell carcinoma in association with the response to cisplatin treatment.
NM23-H1 Expression of Head and Neck Squamous Cell Carcinoma in Association With the Response to Irradiation.
Nm23-H1 immunohistochemical expression in multisteps of cervical carcinogenesis.
Nm23-H1 nuclear expression is associated with a more favourable prognosis in laryngeal carcinoma: univariate and multivariate analysis.
nm23-H1 protein immunoreactivity in intraepithelial neoplasia and invasive squamous cell carcinoma of the uterine cervix.
Nuclear localization of Nm23-H1 in head and neck squamous cell carcinoma is associated with radiation resistance.
Overexpression of nucleoside diphosphate/kinase A/nm23-H1 protein in human lung tumors: association with tumor progression in squamous carcinoma.
[Expression and clinical significance of nm23-H1 and CD44v6 in non-small cell lung cancer].
[Expression of ERK and nm23-H1 in tongue squamous cell carcinoma and its relation with invasion and metastasis].
[Relationship between nm23-H1 expression and lymph node metastasis and prognosis in cervical cancer]
Carcinoma, Transitional Cell
Expression of nm23-H1 in transitional cell carcinoma of the upper urinary tract.
Immunohistochemical evaluation of nm23-H1 gene product in transitional cell carcinoma of the bladder.
Nm23-H1 protein, DNA-ploidy and S-phase fraction in relation to overall survival and disease free survival in transitional cell carcinoma of the bladder.
Prediction of lymph node metastasis based on p53 and nm23-H1 expression in muscle invasive grade III transitional cell carcinoma of bladder.
Cardiomyopathies
Nucleoside Diphosphate Kinase B Contributes to Arrhythmogenesis in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes from a Patient with Arrhythmogenic Right Ventricular Cardiomyopathy.
Cervical Intraepithelial Neoplasia
Clinical significance of high nm23-H1 expression in intraepithelial neoplasia and early-stage squamous cell carcinoma of the uterine cervix.
Concurrent high expression of human telomerase reverse transcriptase and human nonmetastatic clone 23 in high-grade squamous intraepithelial neoplasia and squamous cell carcinoma of uterine cervix.
Down-regulated nucleoside diphosphate kinase nm23-H1 expression is unrelated to high-risk human papillomavirus but associated with progression of cervical intraepithelial neoplasia and unfavourable prognosis in cervical cancer.
Predicting high-risk human papillomavirus infection, progression of cervical intraepithelial neoplasia, and prognosis of cervical cancer with a panel of 13 biomarkers tested in multivariate modeling.
Cholangiocarcinoma
Recruited metastasis suppressor NM23-H2 attenuates expression and activity of peroxisome proliferator-activated receptor ? (PPAR?) in human cholangiocarcinoma.
Cholecystitis
nm23-H1 protein immunoreactivity in cancers of the gallbladder, extrahepatic bile ducts and ampulla of Vater.
Cholera
Conversion of GDP into GTP by nucleoside diphosphate kinase on the GTP-binding proteins.
Differential susceptibility to GTP formed from added GDP via membrane-associated nucleoside diphosphate kinase of GTP-sensitive adenylate cyclases achieved by hormone and cholera toxin.
Choriocarcinoma
Expression of nm23-H1 in hydatidiform mole and its relationship with the development of postmolar disease.
Colonic Neoplasms
Analysis of both NM23-h1 and NM23-H2 expression identifies "at-risk" patients with colorectal cancer.
Coexistence of MACC1 and NM23-H1 dysregulation and tumor budding promise early prognostic evidence for recurrence risk of early-stage colon cancer.
Expression of the nm23 homologues nm23-H4, nm23-H6, and nm23-H7 in human gastric and colon cancer.
Increased nm23-H1 and nm23-H2 messenger RNA expression and absence of mutations in colon carcinomas of low and high metastatic potential.
nm23-H1 expression and loss of heterozygosity in colon adenocarcinoma.
nm23-H1 reduces in vitro cell migration and the liver metastatic potential of colon cancer cells by regulating myosin light chain phosphorylation.
Potential role of nucleoside diphosphate kinase in myricetin-induced selective apoptosis in colon cancer HCT-15?cells.
Reduced metastatic potential and c-myc overexpression of colon adenocarcinoma cells (Colon 26 line) transfected with nm23-R2/rat nucleoside diphosphate kinase alpha isoform.
Survey of molecular profiling during human colon cancer development and progression by immunohistochemical staining on tissue microarray.
Understanding h-prune biology in the fight against cancer.
Colorectal Neoplasms
Analysis of both NM23-h1 and NM23-H2 expression identifies "at-risk" patients with colorectal cancer.
APC gene loss of heterozygosity, mutations, E1317Q, and I1307K germ-line variants in sporadic colon cancer in Croatia.
Association of nm23-H1 allelic deletions with distant metastases in colorectal carcinoma.
CD44v6 and Nm23-H1 protein expression related to clinico pathological parameters in colorectal cancer.
Combined detection of the expression of Nm23-H1 and p53 is correlated with survival rates of patients with stage II and III colorectal cancer.
Dinucleotide repeat polymorphisms at nine loci in sporadic colorectal cancer.
DNA ploidy and S-phase fraction, but not p53 or NM23-H1 expression, predict outcome in colorectal cancer patients. Result of a 5-year prospective study.
Early stage human colorectal cancer: prognostic value of nm23-H1 protein overexpression.
Evaluation of serum nucleoside diphosphate kinase A for the detection of colorectal cancer.
Expression and mutational analysis of Nm23-H1 in liver metastases of colorectal cancer.
Expression of nm23-H1 in colorectal cancer: no association with metastases, histological stage, or survival.
Expression of nm23-H1 predicts lymph node involvement in colorectal carcinoma.
Genomic PCR-SSCP analysis of the metastasis associated NM23-H1 (NME1) gene: a study on colorectal cancer.
High frequency of concomitant nm23-H1 and E-cadherin transcriptional inactivation in primary non-inheriting colorectal carcinomas.
High level of Nm23-H1 gene expression is associated with local colorectal cancer progression not with metastases.
Identification of nicotinamide N-methyltransferase as a novel serum tumor marker for colorectal cancer.
Increased levels of nm23 H1/nucleoside diphosphate kinase A mRNA associated with adenocarcinoma of the prostate.
Inverse association of nm23-H1 expression by colorectal cancer with liver metastasis.
Isolation of human nm23 genomes and analysis of loss of heterozygosity in primary colorectal carcinomas using a specific genomic probe.
Maspin and Nm23-H1 expression in colorectal cancer.
Mutation in the nm23 gene is associated with metastasis in colorectal cancer.
Mutation of the nm23-H1 gene has a non-dominant role in colorectal adenocarcinoma.
NM-23 H1 immunohistochemistry is not useful as predictor of metastatic potential of colorectal cancer.
Nm23-H1 expression does not predict clinical survival in colorectal cancer patients.
NM23-H1 immunostaining is inversely associated with tumour staging but not overall survival or disease recurrence in colorectal carcinomas.
nm23-H1 reduces in vitro cell migration and the liver metastatic potential of colon cancer cells by regulating myosin light chain phosphorylation.
Nucleoside diphosphate kinase 2 confers acquired 5-fluorouracil resistance in colorectal cancer cells.
Overexpression of NDP kinase nm23 associated with ploidy image analysis in colorectal cancer.
Overexpression of nm23-H1 and nm23-H2 genes in colorectal carcinomas and loss of nm23-H1 expression in advanced tumour stages.
Overexpression of nm23-H4 RNA in colorectal and renal tumours.
Prognostic implication of nm23-H1 expression in colorectal carcinomas.
Prognostic significance of the loss of heterozygosity of Nm23-H1 and p53 genes in human colorectal carcinomas.
Reappraisal of the role of NM23-H1 in colorectal cancers.
Somatic allelic deletion of nm23 in human cancer.
Somatic allelic loss at the DCC, APC, nm23-H1 and p53 tumor suppressor gene loci in human prostatic carcinoma.
The Intratumoral Microvessel Density and Expression of bFGF and nm23-H1 in Colorectal Cancer.
The prediction of lymph node metastases in colorectal cancer by expression of the nucleoside diphosphate kinase/nm23-H1 and histopathological variables.
[Adenovirus-mediated delivery of nm23-H1 gene inhibits growth of colorectal carcinoma cell line Lovo].
[Correlation study of allelic gene deletion of nm23-H1 and human colorectal carcinoma metastasis]
[Expression and clinical significance of nm23-H1, Fas and FasL in colorectal carcinoma tissues]
[Expression and clinical significance of vascular endothelial growth factor-C and nm23-H1 in stage II and III colorectal carcinomas].
Cystic Fibrosis
P2Z-Independent and P2Z receptor-mediated macrophage killing by Pseudomonas aeruginosa isolated from cystic fibrosis patients.
Role of Binding and Nucleoside Diphosphate Kinase A in the Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator by AMP-Activated Protein Kinase.
Role of Interaction and Nucleoside Diphosphate Kinase B in Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator Function by cAMP-Dependent Protein Kinase A.
Transglutaminase 2 and nucleoside diphosphate kinase activity are correlated in epithelial membranes and are abnormal in cystic fibrosis.
Dehydration
Characterization of vegetative storage protein (VSP) and low molecular proteins induced by water deficit in stolon of white clover.
Diabetes Mellitus, Type 2
Down-regulation of expression and function of nucleoside diphosphate kinase in insulin-secreting beta-cells under in vitro conditions of glucolipotoxicity.
Diabetic Retinopathy
Nucleoside diphosphate kinase B deficiency causes a diabetes-like vascular pathology via up-regulation of endothelial angiopoietin-2 in the retina.
O-GlcNAcylation of FoxO1 mediates nucleoside diphosphate kinase B deficiency induced endothelial damage.
Role of the Ang2-Tie2 Axis in Vascular Damage Driven by High Glucose or Nucleoside Diphosphate Kinase B Deficiency.
Digestive System Neoplasms
Mutation of the nm23-H1 gene has a non-dominant role in colorectal adenocarcinoma.
Down Syndrome
Human brain nucleoside diphosphate kinase activity is decreased in Alzheimer's disease and Down syndrome.
Reduction of nucleoside diphosphate kinase B, Rab GDP-dissociation inhibitor beta and histidine triad nucleotide-binding protein in fetal Down syndrome brain.
Edema, Cardiac
Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure.
Embolism
Lewis Antigens, alpha1,3 Fucosyltransferses and the Metastatic Potential of Human Primary Liver Cancer.
Endometrial Neoplasms
Expression of nm23-H1 and nm23-H2 protein in endometrial carcinoma.
Nm23 expression in endometrial and cervical cancer: inverse correlation with lymph node involvement and myometrial invasion.
Observations on tumor and metastatic suppressor gene status in endometrial carcinoma with particular emphasis on p53.
Significant association of genetic polymorphism of human nonmetastatic clone 23 type 1 gene with an increased risk of endometrial cancer.
[The expression of nm23-H1 genes with clinical prognosis in endometrial carcinoma]
Endometriosis
Expression of nm23-H1, p53, and integrin ?1 in endometriosis and their clinical significance.
Epstein-Barr Virus Infections
EBNA3C can modulate the activities of the transcription factor Necdin in association with metastasis suppressor protein Nm23-H1.
Epstein-Barr virus protein can upregulate cyclo-oxygenase-2 expression through association with the suppressor of metastasis Nm23-H1.
Esophageal Neoplasms
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
Esophageal Squamous Cell Carcinoma
Downregulation of intracellular nm23-H1 prevents cisplatin-induced DNA damage in oesophageal cancer cells: possible association with Na(+), K(+)-ATPase.
Expression of nm23-H1 gene product in esophageal squamous cell carcinoma and its association with vessel invasion and survival.
Prognostic significance of nm23-H1 expression in esophageal squamous cell carcinoma.
The association between nm23-H1 expression and survival in patients with esophageal squamous cell carcinoma.
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
The nm23-H1 gene as a predictor of sensitivity to chemotherapeutic agents in oesophageal squamous cell carcinoma.
Widely targeted metabolomic analyses unveil the metabolic variations after stable knock-down of NME4 in esophageal squamous cell carcinoma cells.
Fibroadenoma
[Expressions of vascular endothelial growth factor and nm23-H1 gene and their relation to the prognosis of breast cancer in young women.]
Fibrosarcoma
Reduction of invasion in human fibrosarcoma cells by ribosomal protein S3 in conjunction with Nm23-H1 and ERK.
Gallbladder Neoplasms
nm23-H1 protein immunoreactivity in cancers of the gallbladder, extrahepatic bile ducts and ampulla of Vater.
Giant Cell Tumors
Giant cell tumours of the tendon sheath: lack of correlation between nm23-H1 expression and recurrence.
[Association of nm23-H1 with orthopedic oncological conditions]
Glioblastoma
Nm23-h1 protein in oligodendrogliomas.
Targeting SET/I(2)PP2A oncoprotein functions as a multi-pathway strategy for cancer therapy.
Transcription analysis of TIMP-1 and NM23-H1 genes in glioma cell invasion.
Glioma
Acute L-glutamine deprivation affects the expression of TP53-related protein genes in U87 glioma cells.
Analysis of the antibody repertoire of astrocytoma patients against antigens expressed by gliomas.
Expression of Nm23 in gliomas and its effect on migration and invasion in vitro.
Nm23-H1 inhibits the proliferation of glioma cells via regulation of PKC signaling pathway.
Nucleoside diphosphate kinase beta (Nm23-R1/NDPKbeta) is associated with intermediate filaments and becomes upregulated upon cAMP-induced differentiation of rat C6 glioma.
On the availability of certain metabolites at the outer surface of normal and malignant cells for the membranous de novo synthesis of ATP and other nucleotides.
Transcription analysis of TIMP-1 and NM23-H1 genes in glioma cell invasion.
Goiter, Nodular
Analysis of nm23-H1 protein immunoreactivity in follicular thyroid tumors.
Head and Neck Neoplasms
[Expression and anti-metastatic potential of nm 23/NDP kinase in human head and neck cancer cells]
Heart Failure
A Computational Approach for Understanding the Interactions between Graphene Oxide and Nucleoside Diphosphate Kinase with Implications for Heart Failure.
Increased activity of membrane-associated nucleoside diphosphate kinase and inhibition of cAMP synthesis in failing human myocardium.
Nucleoside diphosphate kinase (NDPK, NM23, AWD): recent regulatory advances in endocytosis, metastasis, psoriasis, insulin release, fetal erythroid lineage and heart failure; translational medicine exemplified.
Plasma membrane-associated nucleoside diphosphate kinase (nm23) in the heart is regulated by beta-adrenergic signaling.
Hematologic Neoplasms
Clinical significance of serum NM23-H1 protein in neuroblastoma.
Evaluation by multivariate analysis of the differentiation inhibitory factor nm23 as a prognostic factor in acute myelogenous leukemia and application to other hematologic malignancies.
Extracellular NM23 Protein as a Therapeutic Target for Hematologic Malignancies.
Physiological and pathological relevance of extracellular NM23/NDP kinases.
Plasma levels of the differentiation inhibitory factor nm23-H1 protein and their clinical implications in acute myelogenous leukemia.
Regulatory functions of Nm23-H2 in tumorigenesis: insights from biochemical to clinical perspectives.
Serum nm23-H1 protein as a prognostic factor in hematological malignancies.
Hepatitis
Expression in human hepatocellular carcinoma of nucleoside diphosphate kinase, a homologue of the nm23 gene product.
Hepatitis C
Hepatitis C virus core protein interacts with cellular metastasis suppressor Nm23-H1 and promotes cell migration and invasion.
Hepatitis C Virus E1 protein promotes cell migration and invasion by modulating cellular metastasis suppressor Nm23-H1.
Herpes Zoster
Sensitive and robust gene expression changes in fish exposed to estrogen--a microarray approach.
Hodgkin Disease
A clinicopathological study of nm23-H1 expression in classical Hodgkin's lymphoma.
nm23-H1 expression in non-Hodgkin and Hodgkin lymphomas.
Variability of nm23-H1/NDPK-A expression in human lymphomas and its relation to tumour aggressiveness.
Hydatidiform Mole
Expression of CD44, E-cadherin, and antimetastatic protein nm23-H1 in complete hydatidiform moles.
Expression of nm23-H1 in hydatidiform mole and its relationship with the development of postmolar disease.
Expression of nm23-H1 protein in relation to myometrial invasion in complete hydatidiform moles.
Hyperglycemia
Nucleoside diphosphate kinase B deficiency causes a diabetes-like vascular pathology via up-regulation of endothelial angiopoietin-2 in the retina.
Hypopharyngeal Neoplasms
[Expression of CD44 and nm23-H1 protein in the primary and metastatic lymph node lesions in supraglottic and hypopharyngeal cancer]
Infections
Adenylate kinase of Escherichia coli, a component of the phage T4 dNTP synthetase complex.
Enhanced expression of a gene encoding a nucleoside diphosphate kinase 1 (OsNDPK1) in rice plants upon infection with bacterial pathogens.
Escherichia coli nucleoside diphosphate kinase interactions with T4 phage proteins of deoxyribonucleotide synthesis and possible regulatory functions.
Helicobacter pylori infection induced alteration of gene expression in human gastric cells.
Hepatitis C Virus E1 protein promotes cell migration and invasion by modulating cellular metastasis suppressor Nm23-H1.
Identification of enzymes catalyzing two-step phosphorylation of cidofovir and the effect of cytomegalovirus infection on their activities in host cells.
Metabolic functions of microbial nucleoside diphosphate kinases.
Molecular interactions involving Escherichia coli nucleoside diphosphate kinase.
Ndk, a novel host-responsive regulator, negatively regulates bacterial virulence through quorum sensing in Pseudomonas aeruginosa.
Nucleoside diphosphate kinase and flagellin from Pseudomonas aeruginosa induce interleukin 1 expression via the Akt/NF-?B signaling pathways.
Proteome analysis reveals translational inhibition of Caenorhabditis elegans enhances susceptibility to Pseudomonas aeruginosa PAO1 pathogenesis.
Proteomic analysis of fungal host factors differentially expressed by Fusarium graminearum infected with Fusarium graminearum virus-DK21.
Proteomic profiles of mouse neuro N2a cells infected with variant virulence of rabies viruses.
Infertility, Female
The Enzymatic Activity of Drosophila AWD/NDP Kinase Is Necessary but Not Sufficient for Its Biological Function
The enzymatic activity of Drosophila AWD/NDP kinase is necessary but not sufficient for its biological function.
Insulinoma
Analysis of selected genes in neuroendocrine tumours: insulinomas and phaeochromocytomas.
Keratoacanthoma
Expression of the nucleoside diphosphate kinase in human skin cancers: an immunohistochemical study.
Kidney Neoplasms
Analysis of nm23 gene expressions in human bladder and renal cancers.
Laryngeal Neoplasms
[Expression of CD44v and nm23-H1 proteins in laryngeal carcinoma and its correlation with clinical significance]
[Study on expression of nm23-H1 gene in laryngeal cancer tissues]
Leishmaniasis
Label-free offline versus online activity methods for nucleoside diphosphate kinase b using high performance liquid chromatography.
Leukemia
A cromoglycate binding protein from rat mast cells of a leukemia line is a nucleoside diphosphate kinase.
Alteration of nm23 gene expression during the induced differentiation of human leukemia cell lines.
Differentiation inhibitory factor nm23 as a new prognostic factor in acute monocytic leukemia.
Expression of cell surface NM23 proteins of human leukemia cell lines of various cellular lineage and differentiation stages.
Extracellular NM23 Protein as a Therapeutic Target for Hematologic Malignancies.
Extracellular NM23 protein promotes the growth and survival of primary cultured human acute myelogenous leukemia cells.
Extracellular NM23-H1 protein inhibits the survival of primary cultured normal human peripheral blood mononuclear cells and activates the cytokine production.
nm23-H1 protein expression in newly diagnosed and relapsed childhood acute lymphoblastic leukemia.
Physiological and pathological relevance of extracellular NM23/NDP kinases.
[Analysis of the relationship between nm23-H1 gene and human chronic myeloblastic leukemia using siRNA]
Leukemia, Erythroblastic, Acute
Alteration of nm23 gene expression during the induced differentiation of human leukemia cell lines.
Expression of cell surface NM23 proteins of human leukemia cell lines of various cellular lineage and differentiation stages.
Leukemia, Monocytic, Acute
Differentiation inhibitory factor nm23 as a new prognostic factor in acute monocytic leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Differentiation inhibitory factor nm23 as a new prognostic factor in acute monocytic leukemia.
Evaluation by multivariate analysis of the differentiation inhibitory factor nm23 as a prognostic factor in acute myelogenous leukemia and application to other hematologic malignancies.
Inhibition of nm23-H1 gene expression in chronic myelogenous leukemia cells.
Nm23-H1 regulates the proliferation and differentiation of the human chronic myeloid leukemia K562 cell line: a functional proteomics study.
Plasma levels of the differentiation inhibitory factor nm23-H1 protein and their clinical implications in acute myelogenous leukemia.
[Expression of nm23 genes in acute myeloid leukemia and its clinical significance]
Leukemia, Myeloid
Differentiation inhibitory factor nm23 as a new prognostic factor in acute monocytic leukemia.
Differentiation inhibitory factor Nm23 as a prognostic factor for acute myeloid leukemia.
Expression of cell surface NM23 proteins of human leukemia cell lines of various cellular lineage and differentiation stages.
Inhibitory action of nm23 proteins on induction of erythroid differentiation of human leukemia cells.
Leukemia, Myeloid, Acute
Differentiation inhibitory factor nm23 as a new prognostic factor in acute monocytic leukemia.
Differentiation inhibitory factor Nm23 as a prognostic factor for acute myeloid leukemia.
Evaluation by multivariate analysis of the differentiation inhibitory factor nm23 as a prognostic factor in acute myelogenous leukemia and application to other hematologic malignancies.
Extracellular NM23 Protein as a Therapeutic Target for Hematologic Malignancies.
Extracellular NM23 protein promotes the growth and survival of primary cultured human acute myelogenous leukemia cells.
Extracellular NM23-H1 protein inhibits the survival of primary cultured normal human peripheral blood mononuclear cells and activates the cytokine production.
Nm23-h1 indirectly promotes the survival of acute myeloid leukemia blast cells by binding to more mature components of the leukemic clone.
Plasma levels of the differentiation inhibitory factor nm23-H1 protein and their clinical implications in acute myelogenous leukemia.
Serum nm23-H1 protein as a prognostic factor in hematological malignancies.
[Expression of nm23 genes in acute myeloid leukemia and its clinical significance]
Leukoplakia
[mRNA expression of metastasis-suppressor gene nm23 in carcinoma of buccal mucosa I. Northern blotting study]
[mRNA expression of metastasis-suppressor gene nm23 in carcinoma of buccal mucosa. II. Quantitative reverse transcription PCR amplification]
Liver Diseases
Expression in human hepatocellular carcinoma of nucleoside diphosphate kinase, a homologue of the nm23 gene product.
[Expression of metastasis suppressor gene nm23 in human hepatocellular carcinoma]
Liver Neoplasms
CTCF and EGR1 suppress breast cancer cell migration through transcriptional control of Nm23-H1.
Lewis Antigens, alpha1,3 Fucosyltransferses and the Metastatic Potential of Human Primary Liver Cancer.
Proteome mapping of epidermal growth factor induced hepatocellular carcinomas identifies novel cell metabolism targets and mitogen activated protein kinase signalling events.
Lung Neoplasms
Alteration in gene expression profile and biological behavior in human lung cancer cell line NL9980 by nm23-H1 gene silencing.
Anti-metastatic effects of isolinderalactone via the inhibition of MMP-2 and up regulation of NM23-H1 expression in human lung cancer A549 cells.
Anticancer Effects of Valproic Acid via Regulation of Epigenetic Mechanisms in Non-small-cell Lung Cancer A549 Cell Line.
Co-downregulation of PTEN, KAI-1, and nm23-H1 tumor/metastasis suppressor proteins in non-small cell lung cancer.
Down-regulation of N-acetylglucosaminyltransferase V by tumorigenesis- or metastasis-suppressor gene and its relation to metastatic potential of human hepatocarcinoma cells.
Expression of nm23-H1 gene product in mediastinal lymph nodes from lung cancer patients.
Immunohistochemical analysis of nm23-H1 gene product in node-positive lung cancer and lymph nodes.
Immunohistochemical analysis of nm23-H1 in stage I non-small cell lung cancer: a useful marker in prediction of metastases.
Increased activity of nm23-H1 gene in squamous cell carcinoma of the head and neck is associated with advanced disease and poor prognosis.
Metastasis suppressor Nm23-H1 inhibits STAT3 signaling via a negative feedback mechanism.
Micrometastasis and expression of nm23 messenger RNA of lymph nodes from lung cancer and the postoperative clinical outcome.
nm23-H1 gene driven by hTERT promoter induces inhibition of invasive phenotype and metastasis of lung cancer xenograft in mice.
Nm23-H1 inhibits hypoxia induced epithelial-mesenchymal transition and stemness in non-small cell lung cancer cells.
Nm23-H1 inhibits lung cancer bone-specific metastasis by upregulating miR-660-5p targeted SMARCA5.
nm23-H1 is a negative regulator of TGF-?1-dependent induction of epithelial-mesenchymal transition.
Nm23-H1 is involved in the repair of ionizing radiation-induced DNA double-strand breaks in the A549 lung cancer cell line.
Nm23-H1 Protein Binds to APE1 at AP Sites and Stimulates AP Endonuclease Activity Following Ionizing Radiation of the Human Lung Cancer A549 Cells.
Nm23-H1 was involved in regulation of KAI1 expression in high-metastatic lung cancer cells L9981.
Nm23-H1-stabilized hnRNPA2/B1 promotes internal ribosomal entry site (IRES)-mediated translation of Sp1 in the lung cancer progression.
Prognostic impact of nm23-H1 and PCNA expression in pathologic stage I non-small cell lung cancer.
Prognostic significance of expression of nm23-H1 and focal adhesion kinase in non-small cell lung cancer.
Transcriptional factor FOXO3 negatively regulates the expression of nm23-H1 in non-small cell lung cancer.
Transfection of nm23-H1 increased expression of beta-Catenin, E-Cadherin and TIMP-1 and decreased the expression of MMP-2, CD44v6 and VEGF and inhibited the metastatic potential of human non-small cell lung cancer cell line L9981.
Two serine residues of non-metastasis protein 23-H1 are critical in inhibiting signal transducer and activator of transcription 3 activity in human lung cancer cells.
[A study on the allelic deletion of nm23 genes in human lung cancer.]
[Comparative proteomics study on human high-metastatic large cell lung cancer cell lines before and after transfecting with nm23-H1 gene].
[Construction of the suppression subtractive cDNA libraries of human large cell lung cancer line L9981 before and after transfection with nm23-H1 gene.]
[Effect of Nm23-H1 Nuclear Localization on Proliferation of ?Human Lung Adenocarcinoma Cell Line A549].
[Effect of nm23-H1 on reversing malignant phenotype on human lung cancer cell line L9981]
[Effects of nm23-H1 point mutation on activity of GSK-3? in human high-metastatic large cell lung cancer cell line L9981.]
[Effects of targeting inhibition of ERK1/2 signal transduction pathway on malignant biological behaviors of human high-metastatic large cell lung cancer cell line L9981.]
[Effects of transfection of nm23-H1 gene on ?-catenin expression in human high-metastatic large cell lung cancer cell line L9981.]
[Establishment of a human large cell lung cancer cell line L9981-nm23-H1.]
[Experimental study of effects of nm23-H1 gene transfection on the change of PKA activity in human high-metastasis large cell lung cancer cell line L9981.]
[Experimental study on molecular mechanism of nm23-H1 gene transfection reversing the malignant phenotype of human high-metastatic large cell lung cancer cell line].
[Expression and clinical significance of nm23-H1 and CD44v6 in non-small cell lung cancer].
[Expression and significance of PTEN and nm23-H1 in the metastasis of non-small cell lung cancer.]
[Lentivirus-mediated stable silencing of nm23-H1 gene in lung cancer cells and the influence on biological behavior].
[Molecular mechanism of reversing metastatic phenotype in human high-metastatic large cell lung cancer cell line L9981 by nm23-H1]
[Mutational analysis of nm23-H1 gene in human lung cancer by polymerase chain reaction-single strand conformation polymorphism.]
[nm23-H1 gene inhibits lung cancer cell invasion through down-regulation of PKC signal pathway]
[Northern blot analysis of nm23 gene expression in human lung cancer]
[Regulation of nm23-H1 transfection on expression of integrins in human high-metastasis large cell lung cancer cell line L9981.]
[Slot blot analysis of metastasis suppression gene nm23 expression in human lung cancer]
[Study on invasion and metastasis-associated genes of lung cancer related with NM23-H1 gene].
[Study on protein kinase C translocation before and after transfection of nm23-H1 gene in human lung cancer cells using Laser scanning confocal microscope.]
[Targeting blockage of Wnt signal transduction pathway of nm23-H1 gene transfection in human high-metastatic large cell lung cancer cell line L9981.]
[The correlation between lung cancer lymph node metastasis and nm23-H1 gene mutation, mRNA expression]
[The mechanism and influence on the biological behavior of human high-metastatic large cell lung cancer cell lines with transfection of nm23-H1 gene.]
[The mechanism of metastasis suppressor gene nm23-H1 involving in the Ras signaling of lung cancer.]
[The significance of nm23 gene expression in embryonic tissues and lung cancer tissues.]
[Transcriptional expression of metastasis suppression gene nm23 in human lung cancer.]
[Transfection of the tumor metastasis suppressor gene nm23-H1 can targetly suppress the activity of extracellular signal-regulated protein kinase (ERK) in human high-metastasis large cell lung cancer cell line L9981.]
[Transfection of tumor metastasis suppressor gene nm23-H1 can up-regulate the activity of GSK-3? in human high-metastasis large cell lung cancer cell line L9981.]
Lymphatic Metastasis
Altered expression of nm23-H1 and c-erbB-2 proteins have prognostic significance in adenocarcinoma but not in squamous cell carcinoma of the uterine cervix.
Analysis of nm23-H1 expression in breast cancer. Correlation with p53 expression and clinicopathologic findings.
Clinicopathological features and prognostic significance of nucleoside diphosphate kinase/nm23 gene product in human pancreatic exocrine neoplasms.
Comparative proteomic analysis of beta-catenin-mediated malignant progression of esophageal squamous cell carcinoma.
Estrogen and progestin regulate metastasis through the PI3K/AKT pathway in human ovarian cancer.
Expression of metastasis-related nm23-H1 and nm23-H2 genes in ovarian carcinomas: correlation with clinicopathology, EGFR, c-erbB-2, and c-erbB-3 genes, and sex steroid receptor expression.
Expression of NM23 and tenascin in invasive ductal carcinomas of the breast.
Expression of nm23-H1 predicts lymph node involvement in colorectal carcinoma.
Expression of p16, nm23-H1, E-cadherin, and CD44 gene products and their significance in nasopharyngeal carcinoma.
High expression of human nonmetastatic clone 23 type 1 in cancer of uterine cervix and its association with poor cell differentiation and worse overall survival.
High frequency of concomitant nm23-H1 and E-cadherin transcriptional inactivation in primary non-inheriting colorectal carcinomas.
Immunoreactivities of human nonmetastatic clone 23 and p53 products are disassociated and not good predictors of lymph node metastases in early-stage cervical cancer patients.
Inverse association of nm23-H1 expression by colorectal cancer with liver metastasis.
Nm23 expression in human gastric cancers - possible correlation of nm23 with lymph-node metastasis.
Nm23-H1 expression of metastatic tumors in the lymph nodes is a prognostic indicator of oral squamous cell carcinoma.
Prediction of lymph node metastasis based on p53 and nm23-H1 expression in muscle invasive grade III transitional cell carcinoma of bladder.
Prognostic significance of nm23-H1 expression in esophageal squamous cell carcinoma.
Prognostic significance of the loss of heterozygosity of Nm23-H1 and p53 genes in human colorectal carcinomas.
Reappraisal of the role of NM23-H1 in colorectal cancers.
Somatic allelic deletion of nm23 in human cancer.
Suppressive role of the metastasis-related nm23-H1 gene in human ovarian carcinomas: association of high messenger RNA expression with lack of lymph node metastasis.
Survey of molecular profiling during human colon cancer development and progression by immunohistochemical staining on tissue microarray.
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
The Intratumoral Microvessel Density and Expression of bFGF and nm23-H1 in Colorectal Cancer.
The NM23 gene and its expression in oral squamous cell carcinoma.
The prediction of lymph node metastases in colorectal cancer by expression of the nucleoside diphosphate kinase/nm23-H1 and histopathological variables.
[Expression and clinical significance of nm23-H1 and CD44v6 in non-small cell lung cancer].
[Expression and clinical significance of nm23-H1, Fas and FasL in colorectal carcinoma tissues]
[Expression of CD44V6 and nm23-H1 in thyroid papillary adenocarcinoma and lymph node metastasis]
[Expression of nm23-H1 gene in oral squamous cell carcinoma and its relation to tumor metastasis]
[Expressions of vascular endothelial growth factor and nm23-H1 gene and their relation to the prognosis of breast cancer in young women.]
[Low expression of nm23-H1 mRNA and its protein in breast cancer]
[mRNA expression of metastasis-suppressor gene nm23 in carcinoma of buccal mucosa I. Northern blotting study]
[mRNA expression of metastasis-suppressor gene nm23 in carcinoma of buccal mucosa. II. Quantitative reverse transcription PCR amplification]
[nm23-H1 protein expression and its clinical significance in human laryngeal carcinoma]
[Relationship between nm23-H1 expression and lymph node metastasis and prognosis in cervical cancer]
[Study on expression of nm23-H1 gene in laryngeal cancer tissues]
[Study on expression of nm23-H1 protein/NDPK-A in laryngeal carcinoma]
[The correlation between lung cancer lymph node metastasis and nm23-H1 gene mutation, mRNA expression]
[The expression of nm23-H1 and p53 protein in nasopharyngeal carcinoma]
[The expression of nm23-H1 genes with clinical prognosis in endometrial carcinoma]
[The regulation of nm23-H1/NDPK-A in different processes of regional lymph node metastases of oral squamous cell carcinomas]
Lymphoma
Clinical significance of intracytoplasmic nm23-H1 expression in diffuse large B-cell lymphoma.
Clinical significance of nm23-H1 proteins expressed on cell surface in non-Hodgkin's lymphoma.
Expression of nm23-H1 is associated with poor prognosis in peripheral T-cell lymphoma.
nm23-H1 expression in non-Hodgkin and Hodgkin lymphomas.
Nm23-h1 indirectly promotes the survival of acute myeloid leukemia blast cells by binding to more mature components of the leukemic clone.
nm23-H1 protein expression and gene mutation in 150 patients with non-Hodgkin's lymphomas.
Physiological and pathological relevance of extracellular NM23/NDP kinases.
Prognostic implications of the differentiation inhibitory factor nm23-H1 protein in the plasma of aggressive non-Hodgkin's lymphoma.
Regulation of matrix metalloproteinase 9 expression by Epstein-Barr virus nuclear antigen 3C and the suppressor of metastasis Nm23-H1.
Serum levels of the nm23-H1 protein and their clinical implication in extranodal NK/T-cell lymphoma.
Serum nm23-H1 protein as a prognostic factor for indolent non-Hodgkin's lymphoma.
Serum nm23-H1 protein as a prognostic factor in aggressive non-Hodgkin lymphoma.
Serum nm23-H1 protein as a prognostic factor in hematological malignancies.
Variability of nm23-H1/NDPK-A expression in human lymphomas and its relation to tumour aggressiveness.
Lymphoma, B-Cell
A study on nm23-H1 expression in diffuse large B-cell lymphoma that was treated with CyclOBEAP plus rituximab therapy.
Clinical significance of intracytoplasmic nm23-H1 expression in diffuse large B-cell lymphoma.
Serum nm23-H1 protein as a prognostic factor in aggressive non-Hodgkin lymphoma.
Serum nm23-H1 protein as a prognostic factor in hematological malignancies.
Lymphoma, Large B-Cell, Diffuse
A study on nm23-H1 expression in diffuse large B-cell lymphoma that was treated with CyclOBEAP plus rituximab therapy.
Clinical significance of intracytoplasmic nm23-H1 expression in diffuse large B-cell lymphoma.
Serum nm23-H1 protein as a prognostic factor in aggressive non-Hodgkin lymphoma.
Serum nm23-H1 protein as a prognostic factor in hematological malignancies.
Lymphoma, Non-Hodgkin
Clinical significance of intracytoplasmic nm23-H1 expression in diffuse large B-cell lymphoma.
Clinical significance of nm23-H1 proteins expressed on cell surface in non-Hodgkin's lymphoma.
Expression of nm23-H1 is associated with poor prognosis in peripheral T-cell lymphoma.
nm23-H1 expression in non-Hodgkin and Hodgkin lymphomas.
Nm23-h1 indirectly promotes the survival of acute myeloid leukemia blast cells by binding to more mature components of the leukemic clone.
Prognostic implications of the differentiation inhibitory factor nm23-H1 protein in the plasma of aggressive non-Hodgkin's lymphoma.
Serum nm23-H1 protein as a prognostic factor for indolent non-Hodgkin's lymphoma.
Serum nm23-H1 protein as a prognostic factor in aggressive non-Hodgkin lymphoma.
Serum nm23-H1 protein as a prognostic factor in hematological malignancies.
Variability of nm23-H1/NDPK-A expression in human lymphomas and its relation to tumour aggressiveness.
Lymphoma, T-Cell
Expression of nm23-H1 is associated with poor prognosis in peripheral T-cell lymphoma, not otherwise specified.
Roles of GTP and Rho GTPases in pancreatic islet beta cell function and dysfunction.
Lymphoma, T-Cell, Peripheral
Expression of nm23-H1 is associated with poor prognosis in peripheral T-cell lymphoma, not otherwise specified.
Expression of nm23-H1 is associated with poor prognosis in peripheral T-cell lymphoma.
Serum nm23-H1 protein as a prognostic factor in aggressive non-Hodgkin lymphoma.
The association of nm23-H1 expression with a poor prognosis in patients with peripheral T-cell lymphoma, not otherwise specified.
[Expression and clinical significance of nm23-H1 and MUC-1 in peripheral T-cell lymphoma]
Melanoma
Alteration of nm23 gene expression during the induced differentiation of human leukemia cell lines.
Association between NM23-H1 gene expression and metastasis of human uveal melanoma in an animal model.
c-Abl and Arg induce cathepsin-mediated lysosomal degradation of the NM23-H1 metastasis suppressor in invasive cancer.
Correlation of NM23-H1 cytoplasmic expression with metastatic stage in human prostate cancer tissue.
Downstream targets of Nm23-H1: gene expression profiling of CAL 27 cells using DNA microarray.
Expression of a catalytically inactive H118Y mutant of nm23-H2 suppresses the metastatic potential of line IV Cl 1 human melanoma cells.
Expression of metastasis suppressor gene product, nm23 protein, is not inversely correlated with the tumour progression in human malignant melanomas.
Expression of nm23-H1 in uveal melanoma.
Human nucleoside diphosphate kinase B (Nm23-H2) from melanoma cells shows altered phosphoryl transfer activity due to the S122P mutation.
Identification and characterization of the promoter for the human metastasis suppressor gene nm23-H1.
Immunohistochemical demonstration of the nm23-H1 gene product in human malignant melanoma and Spitz nevi.
Increased nm23-H1 and nm23-H2 messenger RNA expression and absence of mutations in colon carcinomas of low and high metastatic potential.
Isolation and characterization of the human genomic locus coding for the putative metastasis control gene nm23-H1.
Metastasis suppressor function of NM23-H1 requires its 3';-5' exonuclease activity.
Multiple mechanisms underlie metastasis suppressor function of NM23-H1 in melanoma.
Nm23 and breast cancer metastasis.
NM23-H1 and NM23-H2 repress transcriptional activities of nuclease-hypersensitive elements in the platelet-derived growth factor-A promoter.
Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1.
nm23-H1 suppresses invasion of oral squamous cell carcinoma-derived cell lines without modifying matrix metalloproteinase-2 and matrix metalloproteinase-9 expression.
Potential roles of 3'-5' exonuclease activity of NM23-H1 in DNA repair and malignant progression.
Rapid mass spectrometric peptide sequencing and mass matching for characterization of human melanoma proteins isolated by two-dimensional PAGE.
The suppressor of metastasis Nm23-H1 interacts with the Cdc42 Rho family member and the pleckstrin homology domain of oncoprotein Dbl-1 to suppress cell migration.
Transcription effect of nm23-M2/NDP kinase on c-myc oncogene.
YNK1, the yeast homolog of human metastasis suppressor NM23, is required for repair of UV radiation- and etoposide-induced DNA damage.
Melanoma, Experimental
A low molecular weight polysaccharide isolated from Agaricus blazei Murill (LMPAB) exhibits its anti-metastatic effect by down-regulating metalloproteinase-9 and up-regulating Nm23-H1.
Meningioma
Expression of nm23-H1 in human meningioma cells.
Mouth Neoplasms
Nm23-H1 expression of metastatic tumors in the lymph nodes is a prognostic indicator of oral squamous cell carcinoma.
Multiple Myeloma
nm23, TOP2A and VEGF expression: Potential prognostic biologic factors in peripheral T-cell lymphoma, not otherwise specified.
nm23-H1 expression in non-Hodgkin and Hodgkin lymphomas.
Myelodysplastic Syndromes
Elevated plasma level of differentiation inhibitory factor nm23-H1 protein correlates with risk factors for myelodysplastic syndrome.
Evaluation by multivariate analysis of the differentiation inhibitory factor nm23 as a prognostic factor in acute myelogenous leukemia and application to other hematologic malignancies.
Plasma levels of the differentiation inhibitory factor nm23-H1 protein and their clinical implications in acute myelogenous leukemia.
Nasopharyngeal Carcinoma
Downregulated NM23-H1 expression is associated with intracranial invasion of nasopharyngeal carcinoma.
Expression of p16, nm23-H1, E-cadherin, and CD44 gene products and their significance in nasopharyngeal carcinoma.
Identification of nm23-H1 as a metastatic suppressor and prognostic factor in nasopharyngeal carcinoma by proteomic analysis.
Low expression of nm23-H1 associates with poor survival of nasopharyngeal carcinoma patients: A prisma-compliant meta-analysis.
nm23-H1 expression in nasopharyngeal carcinoma: correlation with clinical outcome.
Protein expression of nucleophosmin, annexin A3 and nm23-H1 correlates with human nasopharyngeal carcinoma radioresistance in vivo.
[Expression clinical significance of nm23-H1 and vessel endothelium growth factor protein in nasopharyngeal carcinoma]
[The expression of nm23-H1 and p53 protein in nasopharyngeal carcinoma]
Neoplasm Metastasis
1HN, 13C, and 15N backbone resonance assignments of the SET/TAF-1?/I2PP2A oncoprotein (residues 23-225).
A Drosophila gene that is homologous to a mammalian gene associated with tumor metastasis codes for a nucleoside diphosphate kinase.
A human NDP-kinase B specifically binds single-stranded poly-pyrimidine sequences.
A novel function for the nm23-H1 gene: overexpression in human breast carcinoma cells leads to the formation of basement membrane and growth arrest.
A novel serine/threonine-specific protein phosphotransferase activity of Nm23/nucleoside-diphosphate kinase.
A plant nucleoside diphosphate kinase homologous to the human Nm23 gene product: purification and characterization.
A therapeutic approach to treat prostate cancer by targeting Nm23-H1/h-Prune interaction.
Activation of antimetastatic Nm23-H1 gene expression by estrogen and its alpha-receptor.
Activation of Nm23-H1 to suppress breast cancer metastasis via redox regulation.
Aggregation of the neuroblastoma-associated mutant (S120G) of the human nucleoside diphosphate kinase-A/NM23-H1 into amyloid fibrils.
Alteration in gene expression profile and biological behavior in human lung cancer cell line NL9980 by nm23-H1 gene silencing.
Alteration in protein expression in estrogen receptor alpha-negative human breast cancer tissues indicates a malignant and metastatic phenotype.
Alteration of nuclear protein profiling for NIH-3T3 cells exposed to H?O?.
Alterations in Gemin5 expression contribute to alternative mRNA splicing patterns and tumor cell motility.
Alterations of the metastasis suppressor gene nm23 and the proto-oncogene c-myc in human testicular germ cell tumors.
Altered gene and protein expression by Nm23-H1 in metastasis suppression.
Amplification and overexpression of PRUNE in human sarcomas and breast carcinomas-a possible mechanism for altering the nm23-H1 activity.
Analysis of both NM23-h1 and NM23-H2 expression identifies "at-risk" patients with colorectal cancer.
Analysis of nm23-H1 expression in breast cancer. Correlation with p53 expression and clinicopathologic findings.
Anti-tumor peptide SA12 inhibits metastasis of MDA-MB-231 and MCF-7 breast cancer cells via increasing expression of the tumor metastasis suppressor genes, CDH1, nm23-H1 and BRMS1.
Anticancer Effects of Valproic Acid via Regulation of Epigenetic Mechanisms in Non-small-cell Lung Cancer A549 Cell Line.
Association between NM23-H1 gene expression and metastasis of human uveal melanoma in an animal model.
Association between Nm23-H1 gene expression and metastasis of ovarian carcinoma.
Association of nm23-H1 allelic deletions with distant metastases in colorectal carcinoma.
Bacillus anthracis' PA63 Delivers the Tumor Metastasis Suppressor Protein NDPK-A/NME1 into Breast Cancer Cells.
Basic and translational advances in cancer metastasis: Nm23.
Blockade of extracellular NM23 or its endothelial target slows breast cancer growth and metastasis.
c-Abl and Arg induce cathepsin-mediated lysosomal degradation of the NM23-H1 metastasis suppressor in invasive cancer.
CD44v6 and Nm23-H1 protein expression related to clinico pathological parameters in colorectal cancer.
Cell cycle effects and control of gene expression by resveratrol in human breast carcinoma cell lines with different metastatic potentials.
Cell-permeable NM23 blocks the maintenance and progression of established pulmonary metastasis.
Clinical-translational approaches to the Nm23-H1 metastasis suppressor.
Clinical-translational strategies for the elevation of Nm23-H1 metastasis suppressor gene expression.
Clinicopathological features and prognostic significance of nucleoside diphosphate kinase/nm23 gene product in human pancreatic exocrine neoplasms.
Co-downregulation of PTEN, KAI-1, and nm23-H1 tumor/metastasis suppressor proteins in non-small cell lung cancer.
Comparative proteomic analysis of beta-catenin-mediated malignant progression of esophageal squamous cell carcinoma.
Comparison of p53 gene mutations in paired primary and metastatic gastric tumor tissues.
Constitutive expression of c-fos and c-jun, overexpression of ets-2, and reduced expression of metastasis suppressor gene nm23-H1 in rheumatoid arthritis.
Correlation between nm23-H1 overexpression and clinicopathological variables in human anal canal carcinoma.
Correlation of MDR-1, nm23-H1 and H Sema E gene expression with histopathological findings and clinical outcome in ovarian and breast cancer patients.
Correlation of NM23-H1 cytoplasmic expression with metastatic stage in human prostate cancer tissue.
Correlation of nm23-H1 gene expression with clinical outcome in patients with advanced breast cancer.
Correlation of p16 and nm23-H1 expression levels with incidence and prognosis of soft tissue sarcoma.
Crystal structure of human nucleoside diphosphate kinase A, a metastasis suppressor.
Crystal structure of the Awd nucleotide diphosphate kinase from Drosophila.
Crystallization and preliminary X-ray crystallographic analysis of human nucleoside diphosphate kinase A.
CTCF and EGR1 suppress breast cancer cell migration through transcriptional control of Nm23-H1.
Cytoskeletal association of the A and B nucleoside diphosphate kinases of interphasic but not mitotic human carcinoma cell lines: specific nuclear localization of the B subunit.
Decreased expression of nucleoside diphosphate kinase alpha isoform, an nm23-H2 gene homolog, is associated with metastatic potential of rat mammary-adenocarcinoma cells.
Dexamethasone and medroxyprogesterone acetate elevate Nm23-H1 metastasis suppressor gene expression in metastatic human breast carcinoma cells: new uses for old compounds.
Dictyostelium nucleoside diphosphate kinase highly homologous to Nm23 and Awd proteins involved in mammalian tumor metastasis and Drosophila development.
Differential expression of metastasis-associated genes in papilla of vater and pancreatic cancer correlates with disease stage.
Differential expression patterns of metastasis suppressor proteins in basal cell carcinoma.
Differential regulation of NM23-H1 under hypoxic and serum starvation conditions in metastatic cancer cells and its implication in EMT.
Discrimination between acid and alkali-labile phosphorylated residues on Immobilon: phosphorylation studies of nucleoside diphosphate kinase.
Domain mapping on the human metastasis regulator protein h-Prune reveals a C-terminal dimerization domain.
Double mutant P96S/S120G of Nm23-H1 abrogates its NDPK activity and motility-suppressive ability.
Down-regulation of N-acetylglucosaminyltransferase V by tumorigenesis- or metastasis-suppressor gene and its relation to metastatic potential of human hepatocarcinoma cells.
Downstream targets of Nm23-H1: gene expression profiling of CAL 27 cells using DNA microarray.
Drosophila awdK-pn, a homologue of the metastasis suppressor gene nm23, suppresses the Tum-1 haematopoietic oncogene.
EBNA3C can modulate the activities of the transcription factor Necdin in association with metastasis suppressor protein Nm23-H1.
Effect of Fraxiparine, a type of low molecular weight heparin, on the invasion and metastasis of lung adenocarcinoma A549 cells.
Effects of all-trans retinoic acid and epidermal growth factor on the expression of nm23-H1 in human hepatocarcinoma cells.
Effects of Per2 overexpression on growth inhibition and metastasis, and on MTA1, nm23-H1 and the autophagy-associated PI3K/PKB signaling pathway in nude mice xenograft models of ovarian cancer.
Elevated nm23 protein expression is correlated with diminished progression-free survival in patients with epithelial ovarian carcinoma.
Elevation of breast carcinoma Nm23-H1 metastasis suppressor gene expression and reduced motility by DNA methylation inhibition.
Epstein-Barr virus latent nuclear antigens can induce metastasis in a nude mouse model.
Epstein-Barr virus nuclear antigen 1 interacts with Nm23-H1 in lymphoblastoid cell lines and inhibits its ability to suppress cell migration.
Epstein-Barr virus nuclear protein EBNA-3C interacts with the human metastatic suppressor Nm23-H1: a molecular link to cancer metastasis.
Epstein-Barr virus protein can upregulate cyclo-oxygenase-2 expression through association with the suppressor of metastasis Nm23-H1.
Establishment and characteristics of human hepatocellular carcinoma cells with metastasis to lymph nodes.
Estrogen and progestin regulate HIF-1alpha expression in ovarian cancer cell lines via the activation of Akt signaling transduction pathway.
Estrogen and progestin regulate metastasis through the PI3K/AKT pathway in human ovarian cancer.
Evidence of histidine and aspartic acid phosphorylation in human prostate cancer cells.
Expression analysis of imbalanced genes in prostate carcinoma using tissue microarrays.
Expression and mutational analysis of Nm23-H1 in liver metastases of colorectal cancer.
Expression and significance of heparanase and nm23-H1 in hepatocellular carcinoma.
Expression in human hepatocellular carcinoma of nucleoside diphosphate kinase, a homologue of the nm23 gene product.
Expression of a catalytically inactive H118Y mutant of nm23-H2 suppresses the metastatic potential of line IV Cl 1 human melanoma cells.
Expression of alpha V integrin is modulated by Epstein-Barr virus nuclear antigen 3C and the metastasis suppressor Nm23-H1 through interaction with the GATA-1 and Sp1 transcription factors.
Expression of human nm23-H1 and nm23-H2 proteins in hepatocellular carcinoma.
Expression of metastasis associated proteins, CD44v6 and NM23-H1, in pediatric acute lymphoblastic leukemia.
Expression of metastasis-related nm23-H1 and nm23-H2 genes in ovarian carcinomas: correlation with clinicopathology, EGFR, c-erbB-2, and c-erbB-3 genes, and sex steroid receptor expression.
Expression of NM23 and tenascin in invasive ductal carcinomas of the breast.
Expression of nm23-H1 and nm23-H2 protein in endometrial carcinoma.
Expression of nm23-H1 and nm23-H2 proteins in prostate carcinoma.
Expression of nm23-H1 gene product in mediastinal lymph nodes from lung cancer patients.
Expression of nm23-H1 gene product in sarcomatous cancer cells of renal cell carcinoma: correlation with tumor stage and expression of matrix metalloproteinase-2, matrix metalloproteinase-9, sialyl Lewis X, and c-erbB-2.
Expression of nm23-H1 gene product in thyroid, ovary, and breast cancers.
Expression of nm23-H1 in colorectal cancer: no association with metastases, histological stage, or survival.
Expression of nm23-H1 predicts lymph node involvement in colorectal carcinoma.
Expression of p16, nm23-H1, E-cadherin, and CD44 gene products and their significance in nasopharyngeal carcinoma.
Expression of the nm23 homologues nm23-H4, nm23-H6, and nm23-H7 in human gastric and colon cancer.
Expression of the nucleoside diphosphate kinase in human skin cancers: an immunohistochemical study.
Expression patterns of ER, HER2, and NM23-H1 in breast cancer patients with different menopausal status: correlations with metastasis.
Expressions of Nucleoside Diphosphate Kinase (nm23) in Tumor Tissues are Related with Metastasis and Length of Survival of Patients with Hepatocellular Carcinoma.
Extracellular Vesicle-Mediated Purinergic Signaling Contributes to Host Microenvironment Plasticity and Metastasis in Triple Negative Breast Cancer.
Foot-and-mouth disease virus induces lysosomal degradation of NME1 to impair p53-regulated interferon-inducible antiviral genes expression.
Functional modulation of the metastatic suppressor Nm23-H1 by oncogenic viruses.
Gene structure, promoter activity, and chromosomal location of the DR-nm23 gene, a related member of the nm23 gene family.
Genomic PCR-SSCP analysis of the metastasis associated NM23-H1 (NME1) gene: a study on colorectal cancer.
Glyceraldehyde-3-phosphate dehydrogenase and Nm23-H1/nucleoside diphosphate kinase A. Two old enzymes combine for the novel Nm23 protein phosphotransferase function.
Hepatitis C virus core protein interacts with cellular metastasis suppressor Nm23-H1 and promotes cell migration and invasion.
Hepatitis C Virus E1 protein promotes cell migration and invasion by modulating cellular metastasis suppressor Nm23-H1.
Hepatitis C Virus mediated metastasis in hepatocellular carcinoma as a therapeutic target for cancer management.
High expression of human nonmetastatic clone 23 type 1 in cancer of uterine cervix and its association with poor cell differentiation and worse overall survival.
High expression of NME1 correlates with progression and poor prognosis in patients of hepatocellular carcinoma.
High frequency of concomitant nm23-H1 and E-cadherin transcriptional inactivation in primary non-inheriting colorectal carcinomas.
High level of Nm23-H1 gene expression is associated with local colorectal cancer progression not with metastases.
High levels of p19/nm23 protein in neuroblastoma are associated with advanced stage disease and with N-myc gene amplification.
Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis.
Human metastasis regulator protein H-prune is a short-chain exopolyphosphatase.
Identification and characterization of the promoter for the human metastasis suppressor gene nm23-H1.
Identification of critical genes and gene interaction networks that mediate osteosarcoma metastasis to the lungs.
Identification of structural domains affecting transactivation potential of Nm23.
Identification of the tumor metastasis suppressor Nm23-H1/Nm23-R1 as a constituent of the centrosome.
Immunoexpression of Claudin-1 and Nm23-H1 in Metastatic and Nonmetastatic Lower Lip Squamous-cell Carcinoma.
Immunohistochemical analysis of nm23-H1 expression in human cervical lesions.
Immunohistochemical analysis of nm23-H1 in stage I non-small cell lung cancer: a useful marker in prediction of metastases.
Immunohistochemical analysis of nm23-H1 protein in bladder cancer.
Immunohistochemical analysis of nucleoside diphosphate kinases in oral squamous cell carcinomas.
Immunohistochemical analysis of the nm23 gene product (NDP kinase) expression in astrocytic neoplasms.
Immunohistochemical analysis of the nm23 gene products in testicular seminoma.
Immunohistochemical demonstration of the nm23-H1 gene product in human malignant melanoma and Spitz nevi.
Immunohistochemical evaluation of nm23-H1 gene product in transitional cell carcinoma of the bladder.
Immunohistochemical expression of nm23 gene product, nucleotide diphosphate kinase, in pancreatic neoplasms.
Immunoreactivities of human nonmetastatic clone 23 and p53 products are disassociated and not good predictors of lymph node metastases in early-stage cervical cancer patients.
Impact of laparoscopy on the biological behavior and gene expression of endometrial adenocarcinoma cells.
Implication of human nonmetastatic clone 23 Type 1 and its downstream gene lipocalin 2 in metastasis and patient's survival of cancer of uterine cervix.
Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells.
Increased expression of h-prune is associated with tumor progression and poor survival in gastric cancer.
Increased nm23-H1 and nm23-H2 messenger RNA expression and absence of mutations in colon carcinomas of low and high metastatic potential.
Inhibition of colonization and cell-matrix adhesion after nm23-H1 transfection of human prostate carcinoma cells.
Inhibition of Nm23H2 gene product (NDPK-B) by angiostatin, polyphenols and nucleoside analogs.
Inhibition of signal transduction by the nm23 metastasis suppressor: possible mechanisms.
Inhibitory action of nm23 proteins on induction of erythroid differentiation of human leukemia cells.
Inhibitory activity of nm23-H1 on invasion and colonization of human prostate carcinoma cells is not mediated by its NDP kinase activity.
Inhibitory effects of int-2 gene on the invasion and metastasis of oral cancer cells.
Insights into the biology and prevention of tumor metastasis provided by the Nm23 metastasis suppressor gene.
Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement.
Interaction of the Tumor Metastasis Suppressor Nonmetastatic Protein 23 Homologue H1 and Estrogen Receptor {alpha} Alters Estrogen-Responsive Gene Expression.
Inverse association of nm23-H1 expression by colorectal cancer with liver metastasis.
Isolation and characterization of new microsatellites at the nm23-H1 and nm23-H2 gene loci and application for loss of heterozygosity (LOH) analysis.
Isolation and characterization of the human genomic locus coding for the putative metastasis control gene nm23-H1.
Isolation and characterization of the promoter region of human nm23-H1, a metastasis suppressor gene.
L-carnosine inhibits metastasis of SK-Hep-1 cells by inhibition of matrix metaoproteinase-9 expression and induction of an antimetastatic gene, nm23-H1.
Laparoscopic surgery inhibits the proliferation and metastasis of cervical cancer cells.
Lbc proto-oncogene product binds to and could be negatively regulated by metastasis suppressor nm23-H2.
Lewis Antigens, alpha1,3 Fucosyltransferses and the Metastatic Potential of Human Primary Liver Cancer.
Loss of nm23 and Alu DNA in human lung cancer propagated in nude mice.
Loss of the Metastasis Suppressor NME1, But Not of Its Highly Related Isoform NME2, Induces a Hybrid Epithelial-Mesenchymal State in Cancer Cells.
Lycopene inhibits cell migration and invasion and upregulates Nm23-H1 in a highly invasive hepatocarcinoma, SK-Hep-1 cells.
Mass spectrometry detection of histidine phosphorylation on NM23-H1.
Medroxyprogesterone acetate elevation of Nm23-H1 metastasis suppressor expression in hormone receptor-negative breast cancer.
Metastases suppressor NM23-H2 interaction with G-quadruplex DNA within c-MYC promoter nuclease hypersensitive element induces c-MYC expression.
Metastasis suppression: the evolving role of metastasis suppressor genes for regulating cancer cell growth at the secondary site.
Metastasis suppressor function of NM23-H1 requires its 3';-5' exonuclease activity.
Metastasis suppressor NM23 limits oxidative stress in mammals by preventing activation of stress-activated protein kinases/JNKs through its nucleoside diphosphate kinase activity.
Metastasis suppressor Nm23-H1 inhibits STAT3 signaling via a negative feedback mechanism.
Metastasis suppressor NM23-H1 promotes repair of UV-induced DNA damage and suppresses UV-induced melanomagenesis.
Metastasis Suppressor NME1 Directly Activates Transcription of the ALDOC Gene in Melanoma Cells.
Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance.
Micrometastasis and expression of nm23 messenger RNA of lymph nodes from lung cancer and the postoperative clinical outcome.
MicroRNA-645 promotes metastasis of osteosarcoma via targeting tumor suppressor NM23 nucleoside diphosphate kinase 2.
miR-146a promoted breast cancer proliferation and invasion by regulating NM23-H1.
MMTV-associated transcription factor binding sites increase nm23-H1 metastasis suppressor gene expression in human breast carcinoma cell lines.
Multiple functions of Nm23-H1 are regulated by oxido-reduction system.
Multiple interference of the human papillomavirus-16 E7 oncoprotein with the functional role of the metastasis suppressor Nm23-H1 protein.
Multiple mechanisms underlie metastasis suppressor function of NM23-H1 in melanoma.
Mutation in the nm23 gene is associated with metastasis in colorectal cancer.
Mutation of the nm23-H1 gene has a non-dominant role in colorectal adenocarcinoma.
Mutational analysis of NM23-H2/NDP kinase identifies the structural domains critical to recognition of a c-myc regulatory element.
Mutations at the dimer interface and surface residues of Nm23-H1 metastasis suppressor affect its expression and function.
Nanoparticle delivery of anti-metastatic NM23-H1 gene improves chemotherapy in a mouse tumor model.
NDPKA is not just a metastasis suppressor - be aware of its metastasis-promoting role in neuroblastoma.
Negative regulation of the antimetastatic gene Nm23-H1 by thyroid hormone receptors.
Neuroblastoma specific effects of DR-nm23 and its mutant forms on differentiation and apoptosis.
NM-23 Gene Loss of Heterozygosity and Protein Expression in High-Stage Laryngeal Squamous Cell Carcinomas.
Nm23 expression in human gastric cancers - possible correlation of nm23 with lymph-node metastasis.
NM23 gene product expression does not predict lymph node metastases or survival in young patients with colorectal cancer.
NM23-H1 and NM23-H2 messenger RNA abundance in human hepatocellular carcinoma.
NM23-H1 and NM23-H2 repress transcriptional activities of nuclease-hypersensitive elements in the platelet-derived growth factor-A promoter.
Nm23-H1 Binds to Gelsolin and Inactivates Its Actin-Severing Capacity to Promote Tumor Cell Motility and Metastasis.
Nm23-H1 can induce cell cycle arrest and apoptosis in B cells.
nm23-H1 expression and loss of heterozygosity in colon adenocarcinoma.
Nm23-H1 expression in intrahepatic or extrahepatic metastases of hepatocellular carcinoma.
nm23-H1 expression in nasopharyngeal carcinoma: correlation with clinical outcome.
nm23-H1 expression in salivary adenoid cystic carcinoma in relation to metastasis and survival.
NM23-H1 expression of head and neck squamous cell carcinoma in association with the response to cisplatin treatment.
NM23-H1 Expression of Head and Neck Squamous Cell Carcinoma in Association With the Response to Irradiation.
Nm23-H1 expression of metastatic tumors in the lymph nodes is a prognostic indicator of oral squamous cell carcinoma.
Nm23-H1 gene as a molecular switch between the free-floating and adherent states of gastric cancer cells.
nm23-H1 gene driven by hTERT promoter induces inhibition of invasive phenotype and metastasis of lung cancer xenograft in mice.
nm23-H1 gene expression in ovarian tumors--a potential tumor marker.
Nm23-H1 homologs suppress tumor cell motility and anchorage independent growth.
Nm23-H1 immunohistochemical expression in multisteps of cervical carcinogenesis.
nm23-H1 immunoreactivity as a prognostic factor in differentiated thyroid carcinoma.
NM23-H1 immunostaining is inversely associated with tumour staging but not overall survival or disease recurrence in colorectal carcinomas.
Nm23-H1 inhibits hypoxia induced epithelial-mesenchymal transition and stemness in non-small cell lung cancer cells.
Nm23-H1 inhibits lung cancer bone-specific metastasis by upregulating miR-660-5p targeted SMARCA5.
nm23-H1 is a negative regulator of TGF-?1-dependent induction of epithelial-mesenchymal transition.
Nm23-H1 is involved in the repair of ionizing radiation-induced DNA double-strand breaks in the A549 lung cancer cell line.
Nm23-H1 metastasis suppressor expression level influences the binding properties, stability, and function of the kinase suppressor of Ras1 (KSR1) Erk scaffold in breast carcinoma cells.
Nm23-H1 metastasis suppressor phosphorylation of kinase suppressor of Ras via a histidine protein kinase pathway.
Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1.
Nm23-h1 protein in oligodendrogliomas.
nm23-H1 reduces in vitro cell migration and the liver metastatic potential of colon cancer cells by regulating myosin light chain phosphorylation.
Nm23-H1 regulates the proliferation and differentiation of the human chronic myeloid leukemia K562 cell line: a functional proteomics study.
nm23-H1 suppresses invasion of oral squamous cell carcinoma-derived cell lines without modifying matrix metalloproteinase-2 and matrix metalloproteinase-9 expression.
Nm23-H1 suppresses metastasis by inhibiting expression of the lysophosphatidic acid receptor EDG2.
Nm23-H1 suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2.
NM23-H1 tumor suppressor physically interacts with serine-threonine kinase receptor-associated protein, a transforming growth factor-beta (TGF-beta) receptor-interacting protein, and negatively regulates TGF-beta signaling.
Nm23-H1 was involved in regulation of KAI1 expression in high-metastatic lung cancer cells L9981.
Nm23-H1: genetic alterations and expression patterns in tumor metastasis.
NM23-H2, an estrogen receptor beta-associated protein, shows diminished expression with progression of atherosclerosis.
Nme protein family evolutionary history, a vertebrate perspective.
Nuclear expression of onco-suppressors nm23-H1 and maspin are associated with lower recurrence rate in laryngeal carcinoma.
Nuclear localization of nucleoside diphosphate kinase type B (nm23-H2) in cultured cells.
Nucleoside diphosphate kinase (NDPK, NM23, AWD): recent regulatory advances in endocytosis, metastasis, psoriasis, insulin release, fetal erythroid lineage and heart failure; translational medicine exemplified.
Nucleoside diphosphate kinase (NDPK/NM23) and the waltz with multiple partners: possible consequences in tumor metastasis.
Nucleoside diphosphate kinase A/nm23-H1 promotes metastasis of NB69-derived human neuroblastoma.
Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme.
Nucleoside diphosphate kinase Nm23-H1 regulates chromosomal stability by activating the GTPase dynamin during cytokinesis.
Nucleoside diphosphate kinase/Nm23 and Epstein-Barr virus.
Nucleoside diphosphate kinases (NDPKs) in animal development.
Nucleoside-diphosphate kinase-mediated signal transduction via histidyl-aspartyl phosphorelay systems in Escherichia coli.
Nucleotide-dependent self-assembly of Nucleoside Diphosphate Kinase (NDPK) in vitro.
Oncogenic Epstein-Barr virus recruits Nm23-H1 to regulate chromatin modifiers.
Overexpression of h-prune in breast cancer is correlated with advanced disease status.
Overexpression of nm23-H2/NDP kinase B in a human oral squamous cell carcinoma cell line results in reduced metastasis, differentiated phenotype in the metastatic site, and growth factor-independent proliferative activity in culture.
P53 is a regulator of the metastasis suppressor gene Nm23-H1.
Phosphoglycerate mutase-derived polypeptide inhibits glycolytic flux and induces cell growth arrest in tumor cell lines.
Plakoglobin interacts with and increases the protein levels of metastasis suppressor Nm23-H2 and regulates the expression of Nm23-H1.
Plakoglobin represses SATB1 expression and decreases in vitro proliferation, migration and invasion.
Potential contributions of antimutator activity to the metastasis suppressor function of NM23-H1.
Potential role of nucleoside diphosphate kinase in myricetin-induced selective apoptosis in colon cancer HCT-15?cells.
Potential roles of 3'-5' exonuclease activity of NM23-H1 in DNA repair and malignant progression.
Prediction of lymph node metastasis based on p53 and nm23-H1 expression in muscle invasive grade III transitional cell carcinoma of bladder.
Preferential reduction of nm23-H1 gene product in metastatic tissues from papillary and follicular carcinomas of the thyroid.
Pro-oncogenic potential of NM23-H2 in hepatocellular carcinoma.
Prognostic significance of nm23-H1 expression in esophageal squamous cell carcinoma.
Prognostic significance of the loss of heterozygosity of Nm23-H1 and p53 genes in human colorectal carcinomas.
Prognostic value of nm23 protein expression in renal cell carcinomas.
Proliferation-related expression of p19/nm23 nucleoside diphosphate kinase.
Protein-protein interactions: a mechanism regulating the anti-metastatic properties of Nm23-H1.
Proteomic approach for identification of protein S-nitrosation in mouse gastric mucosa treated with S-nitrosoglutathione.
Prune cAMP phosphodiesterase binds nm23-H1 and promotes cancer metastasis.
Purinergic regulation of angiogenesis by human breast carcinoma-secreted nucleoside diphosphate kinase.
Quaternary structural analysis of nucleoside diphosphate kinases using capillary electrophoresis.
Reappraisal of the role of NM23-H1 in colorectal cancers.
Recruited metastasis suppressor NM23-H2 attenuates expression and activity of peroxisome proliferator-activated receptor ? (PPAR?) in human cholangiocarcinoma.
Reduced expression and rare genomic alteration of nm23-H1 in human hepatocellular carcinoma and hepatoma cell lines.
Reduced expression of nm23-H1, but not of nm23-H2, is concordant with the frequency of lymph-node metastasis of human breast cancer.
Reduced nm 23-H1 messenger RNA expression in metastatic lymph nodes from patients with papillary carcinoma of the thyroid.
Reduction of invasion in human fibrosarcoma cells by ribosomal protein S3 in conjunction with Nm23-H1 and ERK.
Regulation of growth and tumorigenicity of breast cancer cells by the low molecular weight GTPase Rad and nm23.
Regulation of matrix metalloproteinase 9 expression by Epstein-Barr virus nuclear antigen 3C and the suppressor of metastasis Nm23-H1.
Regulation of metastasis suppressor NME1 by a key metabolic cofactor coenzyme A.
Regulation of Nm23-H1 and Cell Invasiveness by Kaposi's Sarcoma-Associated Herpesvirus.
Regulation of the metastasis suppressor Nm23-H1 by tumor viruses.
Regulators affecting the metastasis suppressor activity of Nm23-H1.
Regulatory functions of Nm23-H2 in tumorigenesis: insights from biochemical to clinical perspectives.
Regulatory GTP-binding proteins (ADP-ribosylation factor, Gt, and RAS) are not activated directly by nucleoside diphosphate kinase.
Relationship between expression of CD44v6 and nm23-H1 and tumor invasion and metastasis in hepatocellular carcinoma.
RGS19 upregulates Nm23-H1/2 metastasis suppressors by transcriptional activation via the cAMP/PKA/CREB pathway.
Role of the nm23-H1 gene in the metastasis of gastric cancer.
SET-ting the stage for life and death.
Significance of nm23 mRNA expression in human hepatocellular carcinoma.
Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells.
Small molecule activator of Nm23/NDPK as an inhibitor of metastasis.
Somatic allelic deletion of nm23 in human cancer.
Specific biochemical inactivation of oncogenic Ras proteins by nucleoside diphosphate kinase.
Spontaneous Cell Detachment and Reattachment in Cancer Cell Lines: An In Vitro Model of Metastasis and Malignancy.
Structural comparison of highly similar nucleoside-diphosphate kinases: Molecular explanation of distinct membrane-binding behavior.
Structure of Nm23-H1 under oxidative conditions.
Suppression of alpha-tocopherol ether-linked acetic acid in VEGF-induced angiogenesis and the possible mechanisms in human umbilical vein endothelial cells.
Suppression of MDA-MB-435 breast carcinoma cell metastasis following the introduction of human chromosome 11.
Suppressive role of the metastasis-related nm23-H1 gene in human ovarian carcinomas: association of high messenger RNA expression with lack of lymph node metastasis.
Survey of molecular profiling during human colon cancer development and progression by immunohistochemical staining on tissue microarray.
Targeting SET/I(2)PP2A oncoprotein functions as a multi-pathway strategy for cancer therapy.
The abundance of NM23-H1 mRNA is related with in situ microenvironment and intrahepatic metastasis in hepato-cellular carcinoma.
The centrosomal kinase Aurora-A/STK15 interacts with a putative tumor suppressor NM23-H1.
The dosage-dependent effect exerted by the NM23-H1/H2 homolog NDK-1 on distal tip cell migration in C. elegans.
The effects of gossypol on the invasiveness of MAT-LyLu cells and MAT-LyLu cells from the metastasized lungs of MAT-LyLu-bearing Copenhagen rats.
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
The Intratumoral Microvessel Density and Expression of bFGF and nm23-H1 in Colorectal Cancer.
The metastasis suppressor candidate nucleotide diphosphate kinase NM23 specifically interacts with members of the ROR/RZR nuclear orphan receptor subfamily.
The metastasis suppressor Nm23 as a modulator of Ras/ERK signaling.
The metastasis suppressor NM23-H1 possesses 3'-5' exonuclease activity.
The metastasis suppressor protein NM23-H1 modulates the PI3K-AKT axis through interaction with the p110? catalytic subunit.
The multiple regulation of metastasis suppressor NM23-H1 in cancer.
The NM23 gene and its expression in oral squamous cell carcinoma.
The Nm23-H1 metastasis suppressor as a translational target.
The nucleoside diphosphate kinase activity of DRnm23 is not required for inhibition of differentiation and induction of apoptosis in 32Dcl3 myeloid precursor cells.
The nucleoside diphosphate kinase NDK-1/NME1 promotes phagocytosis in concert with DYN-1/Dynamin.
The prediction of lymph node metastases in colorectal cancer by expression of the nucleoside diphosphate kinase/nm23-H1 and histopathological variables.
The relationship between dNTP pool levels and mutagenesis in an Escherichia coli NDP kinase mutant.
The relationship of NM23 (NME) metastasis suppressor histidine phosphorylation to its nucleoside diphosphate kinase, histidine protein kinase and motility suppression activities.
The role of metastasis suppressor genes in metastatic dormancy.
The role of nm23-H1 in the progression of transitional cell bladder cancer.
The significance of allelic deletions and aneuploidy in colorectal carcinoma. Results of a 5-year follow-up study.
The suppressor of metastasis Nm23-H1 interacts with the Cdc42 Rho family member and the pleckstrin homology domain of oncoprotein Dbl-1 to suppress cell migration.
TIP30 has an intrinsic kinase activity required for up-regulation of a subset of apoptotic genes.
Transcriptional factor FOXO3 negatively regulates the expression of nm23-H1 in non-small cell lung cancer.
Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: effects on tumor metastatic potential, colonization and enzymatic activity.
Transfection of nm23-H1 increased expression of beta-Catenin, E-Cadherin and TIMP-1 and decreased the expression of MMP-2, CD44v6 and VEGF and inhibited the metastatic potential of human non-small cell lung cancer cell line L9981.
Translational approaches using metastasis suppressor genes.
Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor.
Tumour metastasis suppressor, nm23-beta, inhibits gelatinase A transcription by interference with transactivator Y-box protein-1 (YB-1).
Two serine residues of non-metastasis protein 23-H1 are critical in inhibiting signal transducer and activator of transcription 3 activity in human lung cancer cells.
Unraveling genes and pathways influenced by H-prune PDE overexpression: a model to study cellular motility.
YNK1, the yeast homolog of human metastasis suppressor NM23, is required for repair of UV radiation- and etoposide-induced DNA damage.
[A candidate tumor metastasis suppressor Nm23 and NDP kinase]
[A study on the allelic deletion of nm23 genes in human lung cancer.]
[Adenovirus-mediated delivery of nm23-H1 gene inhibits growth of colorectal carcinoma cell line Lovo].
[Cloning and sequencing of nm23-H3b, a new gene identified to nm23]
[Comparative proteomics study on human high-metastatic large cell lung cancer cell lines before and after transfecting with nm23-H1 gene].
[Construction and application of a new prokaryotic expression vector derivative of pBV220]
[Construction and Expression of nm23-H1 Gene with Different Enzyme Activities and Resistant Specific shRNA in Eukaryotic Expression Vector].
[Correlation study of allelic gene deletion of nm23-H1 and human colorectal carcinoma metastasis]
[Effect of nm23-H1 on reversing malignant phenotype on human lung cancer cell line L9981]
[Effects of nm23-H1 point mutation on activity of GSK-3? in human high-metastatic large cell lung cancer cell line L9981.]
[Effects of transfection of nm23-H1 gene on ?-catenin expression in human high-metastatic large cell lung cancer cell line L9981.]
[Effects of tumor metastasis suppressor gene nm23-H1 on invasion and proliferation of cervical cancer cell lines.]
[Establishment and their biological characteristics of clonal cell subpopulations (NL9980 and L9981) from a human lung large cell carcinoma cell line (WCQH-9801).]
[Experimental study of effects of nm23-H1 gene transfection on the change of PKA activity in human high-metastasis large cell lung cancer cell line L9981.]
[Experimental study on molecular mechanism of nm23-H1 gene transfection reversing the malignant phenotype of human high-metastatic large cell lung cancer cell line].
[Expression and anti-metastatic potential of nm 23/NDP kinase in human head and neck cancer cells]
[Expression and clinical significance of nm23-H1 and CD44v6 in non-small cell lung cancer].
[Expression and clinical significance of nm23-H1, Fas and FasL in colorectal carcinoma tissues]
[Expression and implication of CD44 and nm23-H1 proteins in laryngeal carcinoma]
[Expression and significance of PTEN and nm23-H1 in the metastasis of non-small cell lung cancer.]
[Expression clinical significance of nm23-H1 and vessel endothelium growth factor protein in nasopharyngeal carcinoma]
[Expression of CD44v and nm23-H1 proteins in laryngeal carcinoma and its correlation with clinical significance]
[Expression of CD44V6 and nm23-H1 in thyroid papillary adenocarcinoma and lymph node metastasis]
[Expression of ERK and nm23-H1 in tongue squamous cell carcinoma and its relation with invasion and metastasis].
[Expression of metastasis associated proteins, CD44v6 and NM23-H1, in pediatric acute lymphoblastic leukemia]
[Expression of metastasis suppressor gene nm23 in human hepatocellular carcinoma]
[Expression of metastasis suppressor gene nm23-H1 in oral squamous cell carcinoma and its relation to tumor prognosis]
[Expression of nm23-H1 gene in oral squamous cell carcinoma and its relation to tumor metastasis]
[Expression of sialylated carbohydrate antigens and nm23-H1 gene in prognosis of breast cancer]
[Expressions of vascular endothelial growth factor and nm23-H1 gene and their relation to the prognosis of breast cancer in young women.]
[Identification of cDNA fragments related to alpha particles radiation induced neoplastic transformation of rat tracheal epithelial cells]
[In vitro study of the effect of nm23-H1 on metastasis ability and chemo-sensitivity of Acc-M cell lines]
[Influence of estrogen and progestin on nm23-H1 expression in epithelial ovarian cancer cell lines via activation of phosphorylation signaling]
[Inhibitory effect of potential metastasis in SGC-7901 cells induced by beta-ionone]
[Molecular mechanism of reversing metastatic phenotype in human high-metastatic large cell lung cancer cell line L9981 by nm23-H1]
[mRNA expression of metastasis-suppressor gene nm23 in carcinoma of buccal mucosa I. Northern blotting study]
[mRNA expression of metastasis-suppressor gene nm23 in carcinoma of buccal mucosa. II. Quantitative reverse transcription PCR amplification]
[Mutation and expression of nm23-H1 and CD44 gene in prostate cancers]
[Mutational analysis of nm23-H1 gene in human lung cancer by polymerase chain reaction-single strand conformation polymorphism.]
[nm23-H1 gene inhibits lung cancer cell invasion through down-regulation of PKC signal pathway]
[nm23-H1 protein expression and its clinical significance in human laryngeal carcinoma]
[Nucleoside diphosphate kinase/Nm23 and metastatic potency]
[Pathological study on the expression of cell adhesion molecules and metastasis suppressor gene in thyroid follicular carcinoma and papillary carcinoma]
[Regulation of nm23-H1 transfection on expression of integrins in human high-metastasis large cell lung cancer cell line L9981.]
[Relationship between nm23-H1 expression and lymph node metastasis and prognosis in cervical cancer]
[Relationships between intrahepatic metastasis of hepatocellular carcinoma and in situ microenvironment, and the abundance of nm23-H1 H-ras mRNA]
[Slot blot analysis of metastasis suppression gene nm23 expression in human lung cancer]
[Study on expression of nm23-H1 gene in laryngeal cancer tissues]
[Study on expression of nm23-H1 protein/NDPK-A in laryngeal carcinoma]
[Targeting blockage of Wnt signal transduction pathway of nm23-H1 gene transfection in human high-metastatic large cell lung cancer cell line L9981.]
[The correlation between lung cancer lymph node metastasis and nm23-H1 gene mutation, mRNA expression]
[The effects of nm23-H1 gene cell transfection on abilities of invasion, adhension and chemotherapeutic sensitivity of bladder cancer T-24 cell line]
[The effects of nm23-H1 on metastases ability and chemo-sensitivity in Tca8113 cell lines]
[The expression and significance of heparanase and nm23-H1 in hepatocellular carcinoma]
[The expression of nm23-H1 and p53 protein in nasopharyngeal carcinoma]
[The expression of nm23-H1 genes with clinical prognosis in endometrial carcinoma]
[The mechanism and influence on the biological behavior of human high-metastatic large cell lung cancer cell lines with transfection of nm23-H1 gene.]
[The mechanism of metastasis suppressor gene nm23-H1 involving in the Ras signaling of lung cancer.]
[The regulation of nm23-H1/NDPK-A in different processes of regional lymph node metastases of oral squamous cell carcinomas]
[The relationship between nm23-H1 loss of heterozygosity and metastasis in hepatocellular carcinoma]
[The significance of nm23 gene expression in embryonic tissues and lung cancer tissues.]
[Transfection of the nm23-H1 gene into BcaCD885 cell line inhibits the potential of invasion, adhesion and mobility]
[Transfection of the tumor metastasis suppressor gene nm23-H1 can targetly suppress the activity of extracellular signal-regulated protein kinase (ERK) in human high-metastasis large cell lung cancer cell line L9981.]
[Transfection of tumor metastasis suppressor gene nm23-H1 can up-regulate the activity of GSK-3? in human high-metastasis large cell lung cancer cell line L9981.]
Neoplasm Micrometastasis
Expression of nm23-H1 gene product in mediastinal lymph nodes from lung cancer patients.
Micrometastasis and expression of nm23 messenger RNA of lymph nodes from lung cancer and the postoperative clinical outcome.
Neoplasm, Residual
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
Neoplasms
1HN, 13C, and 15N backbone resonance assignments of the SET/TAF-1?/I2PP2A oncoprotein (residues 23-225).
3'-Phosphorylated nucleotides are tight binding inhibitors of nucleoside diphosphate kinase activity.
A Drosophila gene that is homologous to a mammalian gene associated with tumor metastasis codes for a nucleoside diphosphate kinase.
A low molecular weight polysaccharide isolated from Agaricus blazei Murill (LMPAB) exhibits its anti-metastatic effect by down-regulating metalloproteinase-9 and up-regulating Nm23-H1.
A novel serine/threonine-specific protein phosphotransferase activity of Nm23/nucleoside-diphosphate kinase.
A nucleoside diphosphate kinase A (nm23-H1) serine 120-->glycine substitution in advanced stage neuroblastoma affects enzyme stability and alters protein-protein interaction.
A plant nucleoside diphosphate kinase homologous to the human Nm23 gene product: purification and characterization.
A prognostic role for Nm23-H1 in laryngeal carcinoma treated with postoperative radiotherapy: an introductory investigation.
A serine phosphorylation of Nm23, and not its nucleoside diphosphate kinase activity, correlates with suppression of tumor metastatic potential.
A therapeutic approach to treat prostate cancer by targeting Nm23-H1/h-Prune interaction.
Activation of antimetastatic Nm23-H1 gene expression by estrogen and its alpha-receptor.
Activation of Nm23-H1 to suppress breast cancer metastasis via redox regulation.
Alteration in gene expression profile and biological behavior in human lung cancer cell line NL9980 by nm23-H1 gene silencing.
Alterations in Gemin5 expression contribute to alternative mRNA splicing patterns and tumor cell motility.
Alterations of the metastasis suppressor gene nm23 and the proto-oncogene c-myc in human testicular germ cell tumors.
Altered expression of nm23-H1 and c-erbB-2 proteins have prognostic significance in adenocarcinoma but not in squamous cell carcinoma of the uterine cervix.
Altered gene and protein expression by Nm23-H1 in metastasis suppression.
Amplification and overexpression of PRUNE in human sarcomas and breast carcinomas-a possible mechanism for altering the nm23-H1 activity.
Analysis of both NM23-h1 and NM23-H2 expression identifies "at-risk" patients with colorectal cancer.
Analysis of nm23 gene expressions in human bladder and renal cancers.
Analysis of nm23-H1 expression in breast cancer. Correlation with p53 expression and clinicopathologic findings.
Analysis of nm23-H1 protein immunoreactivity in follicular thyroid tumors.
Analysis of oncogenes and tumor suppressor genes in human breast cancer.
Anti-metastatic effects of isolinderalactone via the inhibition of MMP-2 and up regulation of NM23-H1 expression in human lung cancer A549 cells.
Anti-tumor peptide SA12 inhibits metastasis of MDA-MB-231 and MCF-7 breast cancer cells via increasing expression of the tumor metastasis suppressor genes, CDH1, nm23-H1 and BRMS1.
Anticancer Effects of Valproic Acid via Regulation of Epigenetic Mechanisms in Non-small-cell Lung Cancer A549 Cell Line.
APC gene loss of heterozygosity, mutations, E1317Q, and I1307K germ-line variants in sporadic colon cancer in Croatia.
Association between NME1 polymorphisms and cancer susceptibility: A meta-analysis based on 1644 cases and 2038 controls.
Association of nm23 protein levels in human prostates with proliferating cell nuclear antigen expression at autopsy.
Bacillus anthracis' PA63 Delivers the Tumor Metastasis Suppressor Protein NDPK-A/NME1 into Breast Cancer Cells.
Blockade of extracellular NM23 or its endothelial target slows breast cancer growth and metastasis.
c-Abl and Arg induce cathepsin-mediated lysosomal degradation of the NM23-H1 metastasis suppressor in invasive cancer.
Catalysis of DNA cleavage and nucleoside triphosphate synthesis by NM23-H2/NDP kinase share an active site that implies a DNA repair function.
CCR5 Antagonism by Maraviroc Reduces the Potential for Gastric Cancer Cell Dissemination.
CD44v6 and Nm23-H1 protein expression related to clinico pathological parameters in colorectal cancer.
Changes in biomarker expression in the development of prostatic adenocarcinoma.
Changes of histology and expression of MMP-2 and nm23-H1 in primary and metastatic gastric cancer.
Characterization of genetic alteration patterns in human esophageal squamous cell carcinoma using selected microsatellite markers spanning multiple loci.
Clinical significance of high nm23-H1 expression in intraepithelial neoplasia and early-stage squamous cell carcinoma of the uterine cervix.
Clinical significance of nm23 expression in renal cell carcinoma.
Clinical-translational approaches to the Nm23-H1 metastasis suppressor.
Clinical-translational strategies for the elevation of Nm23-H1 metastasis suppressor gene expression.
Clinicopathological features and prognostic significance of nucleoside diphosphate kinase/nm23 gene product in human pancreatic exocrine neoplasms.
Co-downregulation of PTEN, KAI-1, and nm23-H1 tumor/metastasis suppressor proteins in non-small cell lung cancer.
Coexistence of MACC1 and NM23-H1 dysregulation and tumor budding promise early prognostic evidence for recurrence risk of early-stage colon cancer.
Collision tumour in the pelvic cavity: rectal leiomyosarcoma and prostate adenocarcinoma.
Combination of IL-24 and cisplatin inhibits cervical cancer growth in a xenograft nude mice model.
Complementary DNA Encoding nm23/NDP Kinase Gene from the Korean Tiger Shark Scyliorhinus torazame.
Concurrent high expression of human telomerase reverse transcriptase and human nonmetastatic clone 23 in high-grade squamous intraepithelial neoplasia and squamous cell carcinoma of uterine cervix.
Correlation between nm23-H1 overexpression and clinicopathological variables in human anal canal carcinoma.
Correlation of NM23-H1 cytoplasmic expression with metastatic stage in human prostate cancer tissue.
Correlation of nm23-H1 gene expression with clinical outcome in patients with advanced breast cancer.
Correlation of p16 and nm23-H1 expression levels with incidence and prognosis of soft tissue sarcoma.
CTCF and EGR1 suppress breast cancer cell migration through transcriptional control of Nm23-H1.
Cytoskeletal association of the A and B nucleoside diphosphate kinases of interphasic but not mitotic human carcinoma cell lines: specific nuclear localization of the B subunit.
Decreased expression of nucleoside diphosphate kinase alpha isoform, an nm23-H2 gene homolog, is associated with metastatic potential of rat mammary-adenocarcinoma cells.
Diagnostic and biological determinants in undifferentiated and poorly differentiated ovarian carcinomas.
Dictyostelium nucleoside diphosphate kinase highly homologous to Nm23 and Awd proteins involved in mammalian tumor metastasis and Drosophila development.
Different expression of nm23-H1 and nm23-H2 protein with proliferative activities in various sizes of human renal cell carcinoma.
Differential expression of metastasis-associated genes in papilla of vater and pancreatic cancer correlates with disease stage.
Differential regulation of NM23-H1 under hypoxic and serum starvation conditions in metastatic cancer cells and its implication in EMT.
DNA sequences acting as binding sites for NM23/NDPK proteins in melanoma M14 cells.
Down-regulated nucleoside diphosphate kinase nm23-H1 expression is unrelated to high-risk human papillomavirus but associated with progression of cervical intraepithelial neoplasia and unfavourable prognosis in cervical cancer.
Down-regulation of N-acetylglucosaminyltransferase V by tumorigenesis- or metastasis-suppressor gene and its relation to metastatic potential of human hepatocarcinoma cells.
Downregulation of apoptosis-related genes in keloid tissues.
Downregulation of intracellular nm23-H1 prevents cisplatin-induced DNA damage in oesophageal cancer cells: possible association with Na(+), K(+)-ATPase.
Downstream targets of Nm23-H1: gene expression profiling of CAL 27 cells using DNA microarray.
Drosophila awdK-pn, a homologue of the metastasis suppressor gene nm23, suppresses the Tum-1 haematopoietic oncogene.
EBNA3C can modulate the activities of the transcription factor Necdin in association with metastasis suppressor protein Nm23-H1.
Effect of CO2 pneumoperitoneum on the proliferation of human ovarian cancer cell line SKOV-3 and the expression of NM23-H1 and MMP-2.
Elevated nm23 protein expression is correlated with diminished progression-free survival in patients with epithelial ovarian carcinoma.
Epstein-Barr virus latent nuclear antigens can induce metastasis in a nude mouse model.
Epstein-Barr virus nuclear antigen 1 interacts with Nm23-H1 in lymphoblastoid cell lines and inhibits its ability to suppress cell migration.
Epstein-Barr virus nuclear protein EBNA-3C interacts with the human metastatic suppressor Nm23-H1: a molecular link to cancer metastasis.
Epstein-Barr virus protein can upregulate cyclo-oxygenase-2 expression through association with the suppressor of metastasis Nm23-H1.
ER, PgR, HER-2, Ki-67, topoisomerase II?, and nm23-H1 proteins expression as predictors of pathological complete response to neoadjuvant chemotherapy for locally advanced breast cancer.
Estrogen and progestin regulate metastasis through the PI3K/AKT pathway in human ovarian cancer.
Evaluation of ER, PgR, HER-2, Ki-67, cyclin D1, and nm23-H1 as predictors of pathological complete response to neoadjuvant chemotherapy for locally advanced breast cancer.
Evaluation of serum nucleoside diphosphate kinase A for the detection of colorectal cancer.
Evaluation of the expression levels of nm23-H1 mRNA in primary breast cancer, benign breast disease, axillary lymph nodes and normal breast tissue.
Evidence for nm23 RNA overexpression, DNA amplification and mutation in aggressive childhood neuroblastomas.
Expression and mutational analysis of Nm23-H1 in liver metastases of colorectal cancer.
Expression and significance of heparanase and nm23-H1 in hepatocellular carcinoma.
Expression in human hepatocellular carcinoma of nucleoside diphosphate kinase, a homologue of the nm23 gene product.
Expression of antimetastatic gene nm23-H1 in epithelial ovarian cancer.
Expression of cell surface NM23 proteins of human leukemia cell lines of various cellular lineage and differentiation stages.
Expression of human nm23-H1 and nm23-H2 proteins in hepatocellular carcinoma.
Expression of metastasis associated proteins, CD44v6 and NM23-H1, in pediatric acute lymphoblastic leukemia.
Expression of metastasis suppressor gene product, nm23 protein, is not inversely correlated with the tumour progression in human malignant melanomas.
Expression of metastasis-related nm23-H1 and nm23-H2 genes in ovarian carcinomas: correlation with clinicopathology, EGFR, c-erbB-2, and c-erbB-3 genes, and sex steroid receptor expression.
Expression of nm23 antimetastatic gene product in head and neck squamous cell carcinoma.
Expression of nm23 in cell lines derived from patients with metastatic renal cell carcinoma.
Expression of nm23 in gastric carcinoma: association with tumor progression and poor prognosis.
Expression of nm23 protein in adult soft tissue sarcoma is correlated with histological grade.
Expression of nm23-H1 and COX-2 in thyroid papillary carcinoma and microcarcinoma.
Expression of nm23-H1 and nm23-H2 protein in endometrial carcinoma.
Expression of nm23-H1 and nm23-H2 proteins in prostate carcinoma.
Expression of nm23-H1 gene product in mediastinal lymph nodes from lung cancer patients.
Expression of nm23-H1 gene product in sarcomatous cancer cells of renal cell carcinoma: correlation with tumor stage and expression of matrix metalloproteinase-2, matrix metalloproteinase-9, sialyl Lewis X, and c-erbB-2.
Expression of nm23-H1 gene product in thyroid, ovary, and breast cancers.
Expression of nm23-H1 in colorectal cancer: no association with metastases, histological stage, or survival.
Expression of nm23-H1 in human meningioma cells.
Expression of nm23-H1 in prostatic intraepithelial neoplasia and adenocarcinoma.
Expression of nm23-H1 in transitional cell carcinoma of the upper urinary tract.
Expression of nm23-H1 in uveal melanoma.
Expression of nm23-H1 predicts lymph node involvement in colorectal carcinoma.
Expression of nm23-H1 protein in relation to myometrial invasion in complete hydatidiform moles.
Expression of nucleoside diphosphate kinase/nm23 gene product in human pancreatic cancer: an association with lymph node metastasis and tumor invasion.
Expression of p16, nm23-H1, E-cadherin, and CD44 gene products and their significance in nasopharyngeal carcinoma.
Expression of the nm23 homologues nm23-H4, nm23-H6, and nm23-H7 in human gastric and colon cancer.
Expressions of Nucleoside Diphosphate Kinase (nm23) in Tumor Tissues are Related with Metastasis and Length of Survival of Patients with Hepatocellular Carcinoma.
Extracellular NM23 Protein as a Therapeutic Target for Hematologic Malignancies.
Extracellular NM23 protein promotes the growth and survival of primary cultured human acute myelogenous leukemia cells.
Extracellular NM23-H1 protein inhibits the survival of primary cultured normal human peripheral blood mononuclear cells and activates the cytokine production.
Foot-and-mouth disease virus induces lysosomal degradation of NME1 to impair p53-regulated interferon-inducible antiviral genes expression.
Functional modulation of the metastatic suppressor Nm23-H1 by oncogenic viruses.
Giant cell tumours of the tendon sheath: lack of correlation between nm23-H1 expression and recurrence.
H-ras and Nm23-H1 gene expression and proteolytic activity in squamous cell carcinoma of the uterine cervix.
Hepatitis C virus core protein interacts with cellular metastasis suppressor Nm23-H1 and promotes cell migration and invasion.
Hepatitis C Virus E1 protein promotes cell migration and invasion by modulating cellular metastasis suppressor Nm23-H1.
Hepatitis C Virus mediated metastasis in hepatocellular carcinoma as a therapeutic target for cancer management.
High expression of human nonmetastatic clone 23 type 1 in cancer of uterine cervix and its association with poor cell differentiation and worse overall survival.
High level of Nm23-H1 gene expression is associated with local colorectal cancer progression not with metastases.
High levels of nm23 expression are related to cell proliferation in human prostate cancer.
High levels of nm23-H1 and nm23-H2 messenger RNA in human squamous-cell lung carcinoma are associated with poor differentiation and advanced tumor stages.
High levels of p19/nm23 protein in neuroblastoma are associated with advanced stage disease and with N-myc gene amplification.
Histological groups of human postpubertal testicular germ cell tumours harbour different genetic alterations.
Human c-myc transcription factor PuF identified as nm23-H2 nucleoside diphosphate kinase, a candidate suppressor of tumor metastasis.
Human metastasis regulator protein H-prune is a short-chain exopolyphosphatase.
Identification and validation of smoking-related genes in lung adenocarcinoma using an in vitro carcinogenesis model and bioinformatics analysis.
Identification of a second human nm23 gene, nm23-H2.
Identification of ATF-3, caveolin-1, DLC-1, and NM23-H2 as putative antitumorigenic, progesterone-regulated genes for ovarian cancer cells by gene profiling.
Identification of key miRNA-gene pairs in gastric cancer through integrated analysis of mRNA and miRNA microarray.
Identification of potential pharmacogenomic markers of clinical efficacy of 5-fluorouracil in colorectal cancer.
Identification of S100A8 and S100A9 as Serological Markers for Colorectal Cancer.
Identification of the tumor metastasis suppressor Nm23-H1/Nm23-R1 as a constituent of the centrosome.
Immunoexpression of Claudin-1 and Nm23-H1 in Metastatic and Nonmetastatic Lower Lip Squamous-cell Carcinoma.
Immunohistochemical analysis of nm23 gene product/NDP kinase expression in pulmonary adenocarcinoma: lack of prognostic value.
Immunohistochemical analysis of nm23-H1 expression in human cervical lesions.
Immunohistochemical analysis of nm23-H1 gene product in node-positive lung cancer and lymph nodes.
Immunohistochemical analysis of nm23-H1 protein in bladder cancer.
Immunohistochemical analysis of nucleoside diphosphate kinases in oral squamous cell carcinomas.
Immunohistochemical analysis of the nm23 gene product (NDP kinase) expression in astrocytic neoplasms.
Immunohistochemical analysis of the nm23 gene products in testicular seminoma.
Immunohistochemical demonstration of the nm23-H1 gene product in human malignant melanoma and Spitz nevi.
Immunohistochemical evaluation of nm23-H1 gene product in transitional cell carcinoma of the bladder.
Immunohistochemical expression of nm23 gene product, nucleotide diphosphate kinase, in pancreatic neoplasms.
Immunohistologic detection of nm23-H1 protein in squamous cell carcinoma of the vulva.
Immunoreactivity of nm23-H1 protein in renal cell carcinoma.
Implication of human nonmetastatic clone 23 Type 1 and its downstream gene lipocalin 2 in metastasis and patient's survival of cancer of uterine cervix.
Implication of metastasis suppressor NM23-H1 in maintaining adherens junctions and limiting the invasive potential of human cancer cells.
Increased activity of nm23-H1 gene in squamous cell carcinoma of the head and neck is associated with advanced disease and poor prognosis.
Increased expression of h-prune is associated with tumor progression and poor survival in gastric cancer.
Increased nm23 immunoreactivity is associated with selective inhibition of systemic tumour cell dissemination.
Increased nm23-H1 and nm23-H2 messenger RNA expression and absence of mutations in colon carcinomas of low and high metastatic potential.
Independent and differential expression of two isotypes of human Nm23: analysis of the promoter regions of the nm23-H1 and H2 genes.
Inhibition effects of Yuxiao San combined with cisplatin on transplanted tumor growths via upregulation of nm-23 and downregulation of K-ras in Lewis lung cancer mice.
Inhibition of colonization and cell-matrix adhesion after nm23-H1 transfection of human prostate carcinoma cells.
Inhibition of nm23-H1 gene expression in chronic myelogenous leukemia cells.
Inhibition of Nm23H2 gene product (NDPK-B) by angiostatin, polyphenols and nucleoside analogs.
Inhibitory action of nm23 proteins on induction of erythroid differentiation of human leukemia cells.
Insights into the biology and prevention of tumor metastasis provided by the Nm23 metastasis suppressor gene.
Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement.
Interaction of the Tumor Metastasis Suppressor Nonmetastatic Protein 23 Homologue H1 and Estrogen Receptor {alpha} Alters Estrogen-Responsive Gene Expression.
Intracellular levels of S-adenosylhomocysteine but not homocysteine are highly correlated to the expression of nm23-H1 and the level of 5-methyldeoxycytidine in human hepatoma cells with different invasion activities.
Inverse association of nm23-H1 expression by colorectal cancer with liver metastasis.
Inverse expression of dihydrodiol dehydrogenase and glutathione-S-transferase in patients with esophageal squamous cell carcinoma.
Irradiation of rainbow trout at early life stages results in a proteomic legacy in adult gills. Part A; proteomic responses in the irradiated fish and in non-irradiated bystander fish.
Irradiation of rainbow trout at early life stages results in a proteomic legacy in adult gills. Part B; the effect of a second radiation dose, after one year, on the proteomic responses in the irradiated and non-irradiated bystander fish.
Isolation and characterization of the human genomic locus coding for the putative metastasis control gene nm23-H1.
Isolation and characterization of the promoter region of human nm23-H1, a metastasis suppressor gene.
Isolation of human nm23 genomes and analysis of loss of heterozygosity in primary colorectal carcinomas using a specific genomic probe.
Knockdown of ribonuclease inhibitor expression with siRNA in non-invasive bladder cancer cell line BIU-87 promotes growth and metastasis potentials.
Lewis Antigens, alpha1,3 Fucosyltransferses and the Metastatic Potential of Human Primary Liver Cancer.
Localization of a second NM23 gene, NME2, to chromosome 17q21-q22.
Loss of heterozygosity of the nm23-H1 gene in human renal cell carcinomas.
Loss of heterozygosity of tumour suppressor gene loci in human colorectal carcinoma.
Loss of nm23 and Alu DNA in human lung cancer propagated in nude mice.
Lycopene inhibits cell migration and invasion and upregulates Nm23-H1 in a highly invasive hepatocarcinoma, SK-Hep-1 cells.
Maspin and Nm23-H1 expression in colorectal cancer.
Metastasis suppression: the evolving role of metastasis suppressor genes for regulating cancer cell growth at the secondary site.
Metastasis suppressor function of NM23-H1 requires its 3';-5' exonuclease activity.
Metastasis suppressor Nm23-H1 inhibits STAT3 signaling via a negative feedback mechanism.
Metastasis suppressor NM23-H1 promotes repair of UV-induced DNA damage and suppresses UV-induced melanomagenesis.
Metastasis Suppressor NME1 Directly Activates Transcription of the ALDOC Gene in Melanoma Cells.
Micrometastasis and expression of nm23 messenger RNA of lymph nodes from lung cancer and the postoperative clinical outcome.
MicroRNA-645 promotes metastasis of osteosarcoma via targeting tumor suppressor NM23 nucleoside diphosphate kinase 2.
Molecular pathology of hemangiopericytomas accompanied by severe hypoglycemia: oncogenes, tumor-suppressor genes and the insulin-like growth factor family.
Multiple interference of the human papillomavirus-16 E7 oncoprotein with the functional role of the metastasis suppressor Nm23-H1 protein.
Mutation of the nm23 gene, loss of heterozygosity at the nm23 locus and K-ras mutation in ovarian carcinoma: correlation with tumour progression and nm23 gene expression.
Mutation of the nm23-H1 gene has a non-dominant role in colorectal adenocarcinoma.
Mutational analysis of NM23-H2/NDP kinase identifies the structural domains critical to recognition of a c-myc regulatory element.
Mutations in the G-quadruplex silencer element and their relationship to c-MYC overexpression, NM23 repression, and therapeutic rescue.
Nanoparticle delivery of anti-metastatic NM23-H1 gene improves chemotherapy in a mouse tumor model.
NDP kinase can modulate contraction of Dictyostelium cytoskeletons.
Negative regulation of the antimetastatic gene Nm23-H1 by thyroid hormone receptors.
Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction.
NM-23 Gene Loss of Heterozygosity and Protein Expression in High-Stage Laryngeal Squamous Cell Carcinomas.
NM-23 H1 immunohistochemistry is not useful as predictor of metastatic potential of colorectal cancer.
Nm-23, c-erbB-2, and progesterone receptor expression in invasive breast cancer: correlation with clinicopathologic parameters.
Nm23 expression in human gastric cancers - possible correlation of nm23 with lymph-node metastasis.
nm23 in ovarian cancer: correlation with clinical outcome and other clinicopathologic and biochemical prognostic parameters.
nm23--relationship to the metastatic potential of breast carcinoma cell lines, primary human xenografts, and lymph node negative breast carcinoma patients.
NM23-H1 and NM23-H2 gene expression in human renal tumors.
NM23-H1 and NM23-H2 messenger RNA abundance in human hepatocellular carcinoma.
Nm23-H1 Binds to Gelsolin and Inactivates Its Actin-Severing Capacity to Promote Tumor Cell Motility and Metastasis.
Nm23-H1 can induce cell cycle arrest and apoptosis in B cells.
nm23-H1 expression and disease recurrence after surgical resection of small hepatocellular carcinoma.
nm23-H1 expression and loss of heterozygosity in colon adenocarcinoma.
Nm23-H1 expression does not predict clinical survival in colorectal cancer patients.
Nm23-H1 expression in intrahepatic or extrahepatic metastases of hepatocellular carcinoma.
nm23-H1 expression in non-Hodgkin and Hodgkin lymphomas.
nm23-H1 expression in salivary adenoid cystic carcinoma in relation to metastasis and survival.
nm23-H1 Expression in Squamous Cell Carcinoma of the Head and Neck.
NM23-H1 expression of head and neck squamous cell carcinoma in association with the response to cisplatin treatment.
NM23-H1 Expression of Head and Neck Squamous Cell Carcinoma in Association With the Response to Irradiation.
Nm23-H1 expression of metastatic tumors in the lymph nodes is a prognostic indicator of oral squamous cell carcinoma.
Nm23-H1 gene as a molecular switch between the free-floating and adherent states of gastric cancer cells.
nm23-H1 gene driven by hTERT promoter induces inhibition of invasive phenotype and metastasis of lung cancer xenograft in mice.
nm23-H1 gene expression in ovarian tumors--a potential tumor marker.
Nm23-H1 homologs suppress tumor cell motility and anchorage independent growth.
nm23-H1 immunoreactivity as a prognostic factor in differentiated thyroid carcinoma.
NM23-H1 immunostaining is inversely associated with tumour staging but not overall survival or disease recurrence in colorectal carcinomas.
Nm23-h1 indirectly promotes the survival of acute myeloid leukemia blast cells by binding to more mature components of the leukemic clone.
Nm23-H1 inhibits lung cancer bone-specific metastasis by upregulating miR-660-5p targeted SMARCA5.
Nm23-H1 is involved in the repair of ionizing radiation-induced DNA double-strand breaks in the A549 lung cancer cell line.
Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1.
nm23-H1 protein expression in anal canal carcinoma: does it correlate with prognosis?
nm23-H1 protein immunohistochemical expression in human breast cancer.
nm23-H1 protein immunoreactivity in cancers of the gallbladder, extrahepatic bile ducts and ampulla of Vater.
nm23-H1 protein immunoreactivity in intraepithelial neoplasia and invasive squamous cell carcinoma of the uterine cervix.
nm23-H1 protein immunoreactivity in laryngeal carcinoma.
Nm23-h1 protein in oligodendrogliomas.
Nm23-H1 protein, DNA-ploidy and S-phase fraction in relation to overall survival and disease free survival in transitional cell carcinoma of the bladder.
nm23-H1 suppresses invasion of oral squamous cell carcinoma-derived cell lines without modifying matrix metalloproteinase-2 and matrix metalloproteinase-9 expression.
Nm23-H1 suppresses metastasis by inhibiting expression of the lysophosphatidic acid receptor EDG2.
Nm23-H1 suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2.
NM23-H1 tumor suppressor and its interacting partner STRAP activate p53 function.
NM23-H1 tumor suppressor physically interacts with serine-threonine kinase receptor-associated protein, a transforming growth factor-beta (TGF-beta) receptor-interacting protein, and negatively regulates TGF-beta signaling.
Nm23-H1-stabilized hnRNPA2/B1 promotes internal ribosomal entry site (IRES)-mediated translation of Sp1 in the lung cancer progression.
Nm23-H1: genetic alterations and expression patterns in tumor metastasis.
NM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III1.
Nm23-transfected MDA-MB-435 human breast carcinoma cells form tumors with altered phospholipid metabolism and pH: a 31P nuclear magnetic resonance study in vivo and in vitro.
Nme protein family evolutionary history, a vertebrate perspective.
Nuclear localization of Nm23-H1 in head and neck squamous cell carcinoma is associated with radiation resistance.
Nuclear localization of nucleoside diphosphate kinase type B (nm23-H2) in cultured cells.
Nuclear nonmetastatic protein 23-H1 expression and epithelial-mesenchymal transition in laryngeal carcinoma: A pilot investigation.
Nuclear war: the granzyme A-bomb.
Nucleoside diphosphate kinase (NDPK/NM23) and the waltz with multiple partners: possible consequences in tumor metastasis.
Nucleoside diphosphate kinase A/nm23-H1 promotes metastasis of NB69-derived human neuroblastoma.
Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme.
Nucleoside diphosphate kinase Nm23-H1 regulates chromosomal stability by activating the GTPase dynamin during cytokinesis.
Nucleoside diphosphate kinase, a source of GTP, is required for dynamin-dependent synaptic vesicle recycling.
Nucleoside Diphosphate Kinase-3 (NME3) Enhances TLR5-Induced NF-?B Activation.
Nucleoside diphosphate kinase/NM23 expression in breast cancer: lack of correlation with lymph-node metastasis.
Nucleoside-diphosphate kinase-mediated signal transduction via histidyl-aspartyl phosphorelay systems in Escherichia coli.
Nucleotide-dependent self-assembly of Nucleoside Diphosphate Kinase (NDPK) in vitro.
Observations on tumor and metastatic suppressor gene status in endometrial carcinoma with particular emphasis on p53.
Overexpression of h-prune in breast cancer is correlated with advanced disease status.
Overexpression of nm23-H1 and nm23-H2 genes in colorectal carcinomas and loss of nm23-H1 expression in advanced tumour stages.
Overexpression of nm23-H4 RNA in colorectal and renal tumours.
Overexpression of nucleoside diphosphate kinase (Nm23) in solid tumours.
Overexpression of nucleoside diphosphate/kinase A/nm23-H1 protein in human lung tumors: association with tumor progression in squamous carcinoma.
P53 is a regulator of the metastasis suppressor gene Nm23-H1.
Phosphoglycerate mutase-derived polypeptide inhibits glycolytic flux and induces cell growth arrest in tumor cell lines.
Physiological and pathological relevance of extracellular NM23/NDP kinases.
Polymorphisms of human nonmetastatic clone 23 type 1 gene and neoplastic lesions of uterine cervix.
Potential contributions of antimutator activity to the metastasis suppressor function of NM23-H1.
Potential role of nucleoside diphosphate kinase in myricetin-induced selective apoptosis in colon cancer HCT-15?cells.
Predicting high-risk human papillomavirus infection, progression of cervical intraepithelial neoplasia, and prognosis of cervical cancer with a panel of 13 biomarkers tested in multivariate modeling.
Prediction of lymph node metastasis based on p53 and nm23-H1 expression in muscle invasive grade III transitional cell carcinoma of bladder.
Preferential reduction of nm23-H1 gene product in metastatic tissues from papillary and follicular carcinomas of the thyroid.
Prevalence of nucleoside diphosphate kinase autophosphorylation in human colon carcinoma versus normal colon homogenates.
Pro-oncogenic potential of NM23-H2 in hepatocellular carcinoma.
Prognostic implication of nm23-H1 expression in colorectal carcinomas.
Prognostic significance of expression of nm23-H1 and focal adhesion kinase in non-small cell lung cancer.
Prognostic significance of nm23-H1 expression in esophageal squamous cell carcinoma.
Prognostic significance of nm23-H1 expression in oral squamous cell carcinoma.
Prognostic significance of Nm23/NDPK expression in breast carcinoma, assessed on 10-year follow-up by automated and quantitative immunocytochemical assays.
Prognostic significance of the loss of heterozygosity of Nm23-H1 and p53 genes in human colorectal carcinomas.
Prognostic value of nm23 protein expression in renal cell carcinomas.
Proliferation-related expression of p19/nm23 nucleoside diphosphate kinase.
Protein expression of nucleophosmin, annexin A3 and nm23-H1 correlates with human nasopharyngeal carcinoma radioresistance in vivo.
Protein-protein interactions: a mechanism regulating the anti-metastatic properties of Nm23-H1.
Proteome analysis reveals novel proteins associated with proliferation and differentiation of the colorectal cancer cell line Caco-2.
Proteomic approach for identification of protein S-nitrosation in mouse gastric mucosa treated with S-nitrosoglutathione.
Proteomic Profiling for Colorectal Cancer Biomarker Discovery.
PRUNE and NM23-M1 expression in embryonic and adult mouse brain.
Prune cAMP phosphodiesterase binds nm23-H1 and promotes cancer metastasis.
Purinergic regulation of angiogenesis by human breast carcinoma-secreted nucleoside diphosphate kinase.
Quantitation of NM23 expression in human prostate tissues.
Quaternary structural analysis of nucleoside diphosphate kinases using capillary electrophoresis.
Read-through transcript from NM23-H1 into the neighboring NM23-H2 gene encodes a novel protein, NM23-LV.
Reappraisal of the role of NM23-H1 in colorectal cancers.
Reduced expression of nm23-H1, but not of nm23-H2, is concordant with the frequency of lymph-node metastasis of human breast cancer.
Reduced nm 23-H1 messenger RNA expression in metastatic lymph nodes from patients with papillary carcinoma of the thyroid.
Reduction of invasion in human fibrosarcoma cells by ribosomal protein S3 in conjunction with Nm23-H1 and ERK.
Regulation of dynamin by nucleoside diphosphate kinase.
Regulation of Nm23-H1 and Cell Invasiveness by Kaposi's Sarcoma-Associated Herpesvirus.
Regulation of the metastasis suppressor Nm23-H1 by tumor viruses.
Regulators affecting the metastasis suppressor activity of Nm23-H1.
Regulatory functions of Nm23-H2 in tumorigenesis: insights from biochemical to clinical perspectives.
Regulatory GTP-binding proteins (ADP-ribosylation factor, Gt, and RAS) are not activated directly by nucleoside diphosphate kinase.
Relationship between expression of CD44v6 and nm23-H1 and tumor invasion and metastasis in hepatocellular carcinoma.
Secretion of a nucleoside diphosphate kinase (Nm23-H2) by cells from human breast, colon, pancreas and lung tumors.
Selection of putative colorectal cancer markers by applying PCA on the soluble proteome of tumors: NDK A as a promising candidate.
Separating favorable from unfavorable prognostic markers in breast cancer: the role of E-cadherin.
SET-ting the stage for life and death.
Significance of nm23 mRNA expression in human hepatocellular carcinoma.
Small molecule activator of Nm23/NDPK as an inhibitor of metastasis.
Somatic allelic deletion of nm23 in human cancer.
Somatic allelic loss at the DCC, APC, nm23-H1 and p53 tumor suppressor gene loci in human prostatic carcinoma.
Spontaneous Cell Detachment and Reattachment in Cancer Cell Lines: An In Vitro Model of Metastasis and Malignancy.
Squamous cell lung carcinomas: the role of nm23-H1 gene.
Structure of Nm23-H1 under oxidative conditions.
Suppressive role of the metastasis-related nm23-H1 gene in human ovarian carcinomas: association of high messenger RNA expression with lack of lymph node metastasis.
Survey of molecular profiling during human colon cancer development and progression by immunohistochemical staining on tissue microarray.
Targeting SET/I(2)PP2A oncoprotein functions as a multi-pathway strategy for cancer therapy.
Telomerase activity and Nm23-H2 protein expression in hepatocellular carcinoma.
The abundance of NM23-H1 mRNA is related with in situ microenvironment and intrahepatic metastasis in hepato-cellular carcinoma.
The association of nm23-H1 expression with a poor prognosis in patients with peripheral T-cell lymphoma, not otherwise specified.
The centrosomal kinase Aurora-A/STK15 interacts with a putative tumor suppressor NM23-H1.
The crystal structure of a human nucleoside diphosphate kinase, NM23-H2.
The dosage-dependent effect exerted by the NM23-H1/H2 homolog NDK-1 on distal tip cell migration in C. elegans.
The expression and clinical significance of metastasis suppressor gene and matrix metalloproteinase-2 in esophageal squamous cell of carcinoma.
The Function of NM23-H1/NME1 and Its Homologs in Major Processes Linked to Metastasis.
The metastasis suppressor candidate nucleotide diphosphate kinase NM23 specifically interacts with members of the ROR/RZR nuclear orphan receptor subfamily.
The metastasis suppressor Nm23 as a modulator of Ras/ERK signaling.
The metastasis suppressor NM23-H1 possesses 3'-5' exonuclease activity.
The metastasis suppressor protein NM23-H1 modulates the PI3K-AKT axis through interaction with the p110? catalytic subunit.
The multiple regulation of metastasis suppressor NM23-H1 in cancer.
The NM23 gene and its expression in oral squamous cell carcinoma.
The nm23-H1 gene as a predictor of sensitivity to chemotherapeutic agents in oesophageal squamous cell carcinoma.
The nucleoside diphosphate kinase D (NM23-H4) binds the inner mitochondrial membrane with high affinity to cardiolipin and couples nucleotide transfer with respiration.
The potential for clinical application of in vitro assays predicting 5-FU sensitivity in man.
The prediction of lymph node metastases in colorectal cancer by expression of the nucleoside diphosphate kinase/nm23-H1 and histopathological variables.
The relationship between dNTP pool levels and mutagenesis in an Escherichia coli NDP kinase mutant.
The Role of Lipocalin 2 and its Concernment With Human Nonmetastatic Clone 23 Type 1 and p53 in Carcinogenesis of Uterine Cervix.
The role of metastasis suppressor genes in metastatic dormancy.
The role of nm23-H1 in the progression of transitional cell bladder cancer.
The suppressor of metastasis Nm23-H1 interacts with the Cdc42 Rho family member and the pleckstrin homology domain of oncoprotein Dbl-1 to suppress cell migration.
Toponostics of invasive ductal breast carcinoma: combination of spatial protein expression imaging and quantitative proteome signature analysis.
Transcatheter arterial chemoembolization enhances expression of Nm23-H1 and TIMP-2 in the tumor tissue of patients with hepatocellular carcinoma.
Transcription analysis of TIMP-1 and NM23-H1 genes in glioma cell invasion.
Transcriptional factor FOXO3 negatively regulates the expression of nm23-H1 in non-small cell lung cancer.
Transfection of human nm23-H1 into the human MDA-MB-435 breast carcinoma cell line: effects on tumor metastatic potential, colonization and enzymatic activity.
Transfection of nm23-H1 increased expression of beta-Catenin, E-Cadherin and TIMP-1 and decreased the expression of MMP-2, CD44v6 and VEGF and inhibited the metastatic potential of human non-small cell lung cancer cell line L9981.
Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor.
Two serine residues of non-metastasis protein 23-H1 are critical in inhibiting signal transducer and activator of transcription 3 activity in human lung cancer cells.
UV-responsive genes of arabidopsis revealed by similarity to the Gcn4-mediated UV response in yeast.
[A candidate tumor metastasis suppressor Nm23 and NDP kinase]
[A study on the allelic deletion of nm23 genes in human lung cancer.]
[Adenovirus-mediated delivery of nm23-H1 gene inhibits growth of colorectal carcinoma cell line Lovo].
[Amplification, clone and identification of the specific fragments of tumor metastasis-suppressor gene nm23-H1 and nm23-H2]
[Association of nm23-H1 with orthopedic oncological conditions]
[Cloning and sequencing of nm23-H3b, a new gene identified to nm23]
[Comparative proteomics study on human high-metastatic large cell lung cancer cell lines before and after transfecting with nm23-H1 gene].
[Construction and Expression of nm23-H1 Gene with Different Enzyme Activities and Resistant Specific shRNA in Eukaryotic Expression Vector].
[Construction of human nm23-H1 mutant and EGFP fusion genes using site-directed mutagenesis.]
[Effect of nm23-H1 on reversing malignant phenotype on human lung cancer cell line L9981]
[Effect on xenograft of nude mouse by combination therapy of nm23-H1 and protein-cisplatin]
[Effects of transfection of nm23-H1 gene on ?-catenin expression in human high-metastatic large cell lung cancer cell line L9981.]
[Effects of tumor metastasis suppressor gene nm23-H1 on invasion and proliferation of cervical cancer cell lines.]
[Experimental study of effects of nm23-H1 gene transfection on the change of PKA activity in human high-metastasis large cell lung cancer cell line L9981.]
[Experimental study on molecular mechanism of nm23-H1 gene transfection reversing the malignant phenotype of human high-metastatic large cell lung cancer cell line].
[Expression and significance of bcl-2, bax, P53 in neuroendocrine carcinomas of the lung.]
[Expression and significance of PTEN and nm23-H1 in the metastasis of non-small cell lung cancer.]
[Expression clinical significance of nm23-H1 and vessel endothelium growth factor protein in nasopharyngeal carcinoma]
[Expression of CD44 and nm23-H1 protein in the primary and metastatic lymph node lesions in supraglottic and hypopharyngeal cancer]
[Expression of CD44v and nm23-H1 proteins in laryngeal carcinoma and its correlation with clinical significance]
[Expression of ERK and nm23-H1 in tongue squamous cell carcinoma and its relation with invasion and metastasis].
[Expression of metastasis associated proteins, CD44v6 and NM23-H1, in pediatric acute lymphoblastic leukemia]
[Expression of metastasis suppressor gene nm23 in human hepatocellular carcinoma]
[Expression of metastasis suppressor gene nm23-H1 in oral squamous cell carcinoma and its relation to tumor prognosis]
[Expression of nm23-H1 gene in oral squamous cell carcinoma and its relation to tumor metastasis]
[Expressions of vascular endothelial growth factor and nm23-H1 gene and their relation to the prognosis of breast cancer in young women.]
[Feasibility of cationic lipid mediated nm23-h1 plasmid transfecting adnoid cystic carcinoma in vivo]
[Influence of estrogen and progestin on nm23-H1 expression in epithelial ovarian cancer cell lines via activation of phosphorylation signaling]
[Lentivirus-mediated stable silencing of nm23-H1 gene in lung cancer cells and the influence on biological behavior].
[Low expression of nm23-H1 mRNA and its protein in breast cancer]
[Molecular mechanism of reversing metastatic phenotype in human high-metastatic large cell lung cancer cell line L9981 by nm23-H1]
[nm23-H1 protein expression and its clinical significance in human laryngeal carcinoma]
[Nucleoside diphosphate kinase (NM23) and cancer]
[Nucleoside diphosphate kinase/Nm23 and metastatic potency]
[Prognostic significance of selected oncogene and suppressor gene expression in follicular thyroid carcinoma]
[Slot blot analysis of metastasis suppression gene nm23 expression in human lung cancer]
[Study on expression of nm23-H1 gene in laryngeal cancer tissues]
[Study on expression of nm23-H1 protein/NDPK-A in laryngeal carcinoma]
[Targeting blockage of Wnt signal transduction pathway of nm23-H1 gene transfection in human high-metastatic large cell lung cancer cell line L9981.]
[The expression and significance of heparanase and nm23-H1 in hepatocellular carcinoma]
[The mechanism and influence on the biological behavior of human high-metastatic large cell lung cancer cell lines with transfection of nm23-H1 gene.]
[The mechanism of metastasis suppressor gene nm23-H1 involving in the Ras signaling of lung cancer.]
[The significance of nm23 gene expression in embryonic tissues and lung cancer tissues.]
[Transcriptional expression of metastasis suppression gene nm23 in human lung cancer.]
[Transfection of the tumor metastasis suppressor gene nm23-H1 can targetly suppress the activity of extracellular signal-regulated protein kinase (ERK) in human high-metastasis large cell lung cancer cell line L9981.]
[Transfection of tumor metastasis suppressor gene nm23-H1 can up-regulate the activity of GSK-3? in human high-metastasis large cell lung cancer cell line L9981.]
[Ultrastructural immunocytochemical localization of diphosphate kinase/Nm23 in human cancer cells]
Neoplasms, Germ Cell and Embryonal
Alterations of the metastasis suppressor gene nm23 and the proto-oncogene c-myc in human testicular germ cell tumors.
Neuroblastoma
A nucleoside diphosphate kinase A (nm23-H1) serine 120-->glycine substitution in advanced stage neuroblastoma affects enzyme stability and alters protein-protein interaction.
A point mutation of human nucleoside diphosphate kinase A found in aggressive neuroblastoma affects protein folding.
A therapeutic approach to treat prostate cancer by targeting Nm23-H1/h-Prune interaction.
Acetylation of NDPK-D Regulates Its Subcellular Localization and Cell Survival.
AMPK directly inhibits NDPK through a phosphoserine switch to maintain cellular homeostasis.
Amplification and overexpression of PRUNE in human sarcomas and breast carcinomas-a possible mechanism for altering the nm23-H1 activity.
Clinical significance of serum NM23-H1 protein in neuroblastoma.
Correlation of NM23-H1 cytoplasmic expression with metastatic stage in human prostate cancer tissue.
Effect of retinoic acid on Nm/23 nucleoside diphosphate kinase and components of cyclic adenosine monophosphate-dependent signalling in human neuroblastoma cell lines.
Evidence for interaction between human PRUNE and nm23-H1 NDPKinase.
High levels of p19/nm23 protein in neuroblastoma are associated with advanced stage disease and with N-myc gene amplification.
Increased levels of nm23 H1/nucleoside diphosphate kinase A mRNA associated with adenocarcinoma of the prostate.
Molecular cytogenetic delineation of 17q translocation breakpoints in neuroblastoma cell lines.
NDPKA is not just a metastasis suppressor - be aware of its metastasis-promoting role in neuroblastoma.
Neuroblastoma specific effects of DR-nm23 and its mutant forms on differentiation and apoptosis.
Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction.
Nm23-H1 mutation in neuroblastoma.
Nucleoside diphosphate kinase A/nm23-H1 promotes metastasis of NB69-derived human neuroblastoma.
Point mutations affecting the oligomeric structure of Nm23-H1 abrogates its inhibitory activity on colonization and invasion of prostate cancer cells.
Protein phosphorylation corrects the folding defect of the neuroblastoma (S120G) mutant of human nucleoside diphosphate kinase A/Nm23-H1.
Read-through transcript from NM23-H1 into the neighboring NM23-H2 gene encodes a novel protein, NM23-LV.
Rescue of the neuroblastoma mutant of the human nucleoside diphosphate kinase A/nm23-H1 by the natural osmolyte trimethylamine-N-oxide.
Site-directed mutagenesis of nm23-H1. Mutation of proline 96 or serine 120 abrogates its motility inhibitory activity upon transfection into human breast carcinoma cells.
The N-myc and c-myc downstream pathways include the chromosome 17q genes nm23-H1 and nm23-H2.
Neurodegenerative Diseases
Human brain nucleoside diphosphate kinase activity is decreased in Alzheimer's disease and Down syndrome.
Nevus
Immunohistochemical demonstration of the nm23-H1 gene product in human malignant melanoma and Spitz nevi.
nucleoside-diphosphate kinase deficiency
Adenylate kinase complements nucleoside diphosphate kinase deficiency in nucleotide metabolism.
Escherichia coli strains (ndk) lacking nucleoside diphosphate kinase are powerful mutators for base substitutions and frameshifts in mismatch-repair-deficient strains.
Involvement of NDPK-B in Glucose Metabolism-Mediated Endothelial Damage via Activation of the Hexosamine Biosynthesis Pathway and Suppression of O-GlcNAcase Activity.
Metastasis suppressor NM23-H1 promotes repair of UV-induced DNA damage and suppresses UV-induced melanomagenesis.
Nucleoside diphosphate kinase B deficiency causes a diabetes-like vascular pathology via up-regulation of endothelial angiopoietin-2 in the retina.
O-GlcNAcylation of FoxO1 mediates nucleoside diphosphate kinase B deficiency induced endothelial damage.
Role of the Ang2-Tie2 Axis in Vascular Damage Driven by High Glucose or Nucleoside Diphosphate Kinase B Deficiency.
Oligodendroglioma
Nm23-h1 protein in oligodendrogliomas.
Osteosarcoma
A therapeutic approach to treat prostate cancer by targeting Nm23-H1/h-Prune interaction.
Increased expression of nucleoside diphosphate kinase/nm23 and c-Ha-ras mRNA is associated with spontaneous lung metastasis in rat-transplantable osteosarcomas.
Interaction of the Tumor Metastasis Suppressor Nonmetastatic Protein 23 Homologue H1 and Estrogen Receptor {alpha} Alters Estrogen-Responsive Gene Expression.
MicroRNA-645 promotes metastasis of osteosarcoma via targeting tumor suppressor NM23 nucleoside diphosphate kinase 2.
Nucleoside diphosphate kinase B promotes osteosarcoma proliferation through c-Myc.
[Association of nm23-H1 with orthopedic oncological conditions]
Ovarian Neoplasms
Correlation of MDR-1, nm23-H1 and H Sema E gene expression with histopathological findings and clinical outcome in ovarian and breast cancer patients.
Effect of CO2 pneumoperitoneum on the proliferation of human ovarian cancer cell line SKOV-3 and the expression of NM23-H1 and MMP-2.
Effects of Per2 overexpression on growth inhibition and metastasis, and on MTA1, nm23-H1 and the autophagy-associated PI3K/PKB signaling pathway in nude mice xenograft models of ovarian cancer.
Estrogen and progestin regulate metastasis through the PI3K/AKT pathway in human ovarian cancer.
Expression of nm23-H1 gene product in thyroid, ovary, and breast cancers.
Identification of ATF-3, caveolin-1, DLC-1, and NM23-H2 as putative antitumorigenic, progesterone-regulated genes for ovarian cancer cells by gene profiling.
Pancreatic Neoplasms
Differential expression of metastasis-associated genes in papilla of vater and pancreatic cancer correlates with disease stage.
Immunohistochemical expression of nm23 gene product, nucleotide diphosphate kinase, in pancreatic neoplasms.
Papilloma
Functional modulation of the metastatic suppressor Nm23-H1 by oncogenic viruses.
[The expression of nm23-H1 in the investing papilloma and it's cancerated tissue of nasal cavity and parasinuses]
Pleural Effusion, Malignant
[Mutational analysis of nm23-H1 gene in human lung cancer by polymerase chain reaction-single strand conformation polymorphism.]
Pneumoperitoneum
Effect of CO2 pneumoperitoneum on the proliferation of human ovarian cancer cell line SKOV-3 and the expression of NM23-H1 and MMP-2.
Polycystic Kidney Diseases
A shotgun proteomic approach reveals novel potential salivary protein biomarkers for asthma.
Polycystic Kidney, Autosomal Recessive
A shotgun proteomic approach reveals novel potential salivary protein biomarkers for asthma.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Evaluation by multivariate analysis of the differentiation inhibitory factor nm23 as a prognostic factor in acute myelogenous leukemia and application to other hematologic malignancies.
Expression of metastasis associated proteins, CD44v6 and NM23-H1, in pediatric acute lymphoblastic leukemia.
nm23-H1 protein expression in newly diagnosed and relapsed childhood acute lymphoblastic leukemia.
Plasma levels of the differentiation inhibitory factor nm23-H1 protein and their clinical implications in acute myelogenous leukemia.
[Expression of metastasis associated proteins, CD44v6 and NM23-H1, in pediatric acute lymphoblastic leukemia]
[Expression of nm23 genes in acute myeloid leukemia and its clinical significance]
Prostatic Hyperplasia
Expression of nm23-H1 and nm23-H2 proteins in prostate carcinoma.
Prostatic Intraepithelial Neoplasia
Expression of nm23-H1 in prostatic intraepithelial neoplasia and adenocarcinoma.
Prostatic Neoplasms
A therapeutic approach to treat prostate cancer by targeting Nm23-H1/h-Prune interaction.
Association of nm23 protein levels in human prostates with proliferating cell nuclear antigen expression at autopsy.
Correlation of NM23-H1 cytoplasmic expression with metastatic stage in human prostate cancer tissue.
EGFR-upregulated LIFR promotes SUCLG2-dependent castration resistance and neuroendocrine differentiation of prostate cancer.
Evidence of histidine and aspartic acid phosphorylation in human prostate cancer cells.
High levels of nm23 expression are related to cell proliferation in human prostate cancer.
Point mutations affecting the oligomeric structure of Nm23-H1 abrogates its inhibitory activity on colonization and invasion of prostate cancer cells.
Quantitation of NM23 expression in human prostate tissues.
[Mutation and expression of nm23-H1 and CD44 gene in prostate cancers]
Psoriasis
Novel roles of NM23 proteins in skin homeostasis, repair and disease.
Nucleoside diphosphate kinase (NDPK, NM23, AWD): recent regulatory advances in endocytosis, metastasis, psoriasis, insulin release, fetal erythroid lineage and heart failure; translational medicine exemplified.
Rectal Neoplasms
Tissue microarrays in chinese human rectal cancer: study of expressions of the tumor-associated genes.
Retinoblastoma
Histological groups of human postpubertal testicular germ cell tumours harbour different genetic alterations.
Nucleoside diphosphate kinase (nm23 protein) expression in retinoblastoma.
Observations on tumor and metastatic suppressor gene status in endometrial carcinoma with particular emphasis on p53.
Sarcoma
Amplification and overexpression of PRUNE in human sarcomas and breast carcinomas-a possible mechanism for altering the nm23-H1 activity.
Correlation of p16 and nm23-H1 expression levels with incidence and prognosis of soft tissue sarcoma.
High levels of nm23-H1 and nm23-H2 messenger RNA in human squamous-cell lung carcinoma are associated with poor differentiation and advanced tumor stages.
Sarcoma, Kaposi
Functional modulation of the metastatic suppressor Nm23-H1 by oncogenic viruses.
Schistosomiasis
Investigating Immunization With Nucleotide Enzymes of Schistosoma mansoni: Nucleoside Diphosphate Kinase and Adenylosuccinate Lyase as New Antigenic Targets Against Schistosomiasis.
Seizures
Brain protein metabolism in epilepsy.
Seminoma
Alterations of the metastasis suppressor gene nm23 and the proto-oncogene c-myc in human testicular germ cell tumors.
Histological groups of human postpubertal testicular germ cell tumours harbour different genetic alterations.
Immunohistochemical analysis of the nm23 gene products in testicular seminoma.
Severe Combined Immunodeficiency
Nm23-transfected MDA-MB-435 human breast carcinoma cells form tumors with altered phospholipid metabolism and pH: a 31P nuclear magnetic resonance study in vivo and in vitro.
Sinusitis
[The expression of nm23-H1 in the investing papilloma and it's cancerated tissue of nasal cavity and parasinuses]
Skin Diseases
Novel roles of NM23 proteins in skin homeostasis, repair and disease.
Skin Neoplasms
Expression of the nucleoside diphosphate kinase in human skin cancers: an immunohistochemical study.
Small Cell Lung Carcinoma
[Northern blot analysis of nm23 gene expression in human lung cancer]
Squamous Cell Carcinoma of Head and Neck
A high nuclear nm23-H1 expression is associated with a better prognosis in elderly patients with laryngeal carcinoma.
Downstream targets of Nm23-H1: gene expression profiling of CAL 27 cells using DNA microarray.
Gene expression profiling of Nm23-H2 overexpressing CAL 27 cells using DNA microarray.
Immunohistochemical analysis of nucleoside diphosphate kinases in oral squamous cell carcinomas.
NM23-H1 expression of head and neck squamous cell carcinoma in association with the response to cisplatin treatment.
NM23-H1 Expression of Head and Neck Squamous Cell Carcinoma in Association With the Response to Irradiation.
Nm23-H1 expression of metastatic tumors in the lymph nodes is a prognostic indicator of oral squamous cell carcinoma.
nm23-H1 protein immunoreactivity in laryngeal carcinoma.
nm23-H1 suppresses invasion of oral squamous cell carcinoma-derived cell lines without modifying matrix metalloproteinase-2 and matrix metalloproteinase-9 expression.
Nuclear expression of onco-suppressors nm23-H1 and maspin are associated with lower recurrence rate in laryngeal carcinoma.
Nuclear localization of Nm23-H1 in head and neck squamous cell carcinoma is associated with radiation resistance.
Nuclear nonmetastatic protein 23-H1 expression and epithelial-mesenchymal transition in laryngeal carcinoma: A pilot investigation.
Prognostic significance of nm23-H1 expression in oral squamous cell carcinoma.
Regulation of cellular functions by nucleoside diphosphate kinases in mammals.
Value of ezrin, maspin and nm23-H1 protein expressions in predicting outcome of patients with head and neck squamous-cell carcinoma treated with radical radiotherapy.
[Expression of metastasis suppressor gene nm23-H1 in oral squamous cell carcinoma and its relation to tumor prognosis]
[Expression of nm23-H1 gene in oral squamous cell carcinoma and its relation to tumor metastasis]
[Expression of vascular endothelial growth factor, vascular endothelial growth factor receptor-3 and nm23-H1 in oral squamous cell carcinoma]
[Study on expression of nm23-H1 gene in laryngeal cancer tissues]
[Study on expression of nm23-H1 protein/NDPK-A in laryngeal carcinoma]
Starvation
Differential regulation of NM23-H1 under hypoxic and serum starvation conditions in metastatic cancer cells and its implication in EMT.
Two separate functions of NME3 critical for cell survival underlie a neurodegenerative disorder.
Stomach Neoplasms
Changes of histology and expression of MMP-2 and nm23-H1 in primary and metastatic gastric cancer.
Distant metastasis of gastric cancer is associated with elevated expression of the antimetastatic nm23 gene.
Expression of the nm23 homologues nm23-H4, nm23-H6, and nm23-H7 in human gastric and colon cancer.
Increased expression of h-prune is associated with tumor progression and poor survival in gastric cancer.
Nm23 expression in human gastric cancers - possible correlation of nm23 with lymph-node metastasis.
Nm23-H1 gene as a molecular switch between the free-floating and adherent states of gastric cancer cells.
NME2 Is a Master Suppressor of Apoptosis in Gastric Cancer Cells via Transcriptional Regulation of miR-100 and Other Survival Factors.
Role of the nm23-H1 gene in the metastasis of gastric cancer.
The differential proteome profile of stomach cancer: identification of the biomarker candidates.
Stroke
PARK7 and nucleoside diphosphate kinase A as plasma markers for the early diagnosis of stroke.
Thrombosis
NM23-H1 and NM23-H2 messenger RNA abundance in human hepatocellular carcinoma.
Thyroid Neoplasms
Analysis of nm23-H1 protein immunoreactivity in follicular thyroid tumors.
Expression of nm23-H1 and COX-2 in thyroid papillary carcinoma and microcarcinoma.
Expression of nm23-H1 gene product in thyroid, ovary, and breast cancers.
Immunohistochemical detection of nm23-H1/NDP kinase in childhood thyroid carcinoma.
nm23-H1 immunoreactivity as a prognostic factor in differentiated thyroid carcinoma.
Preferential reduction of nm23-H1 gene product in metastatic tissues from papillary and follicular carcinomas of the thyroid.
[Pathological study on the expression of cell adhesion molecules and metastasis suppressor gene in thyroid follicular carcinoma and papillary carcinoma]
Triple Negative Breast Neoplasms
CK5/6, EGFR, Ki-67, cyclin D1, and nm23-H1 protein expressions as predictors of pathological complete response to neoadjuvant chemotherapy in triple-negative breast cancer patients.
Tuberculosis
Amino acid residues involved in autophosphorylation and phosphotransfer activities are distinct in nucleoside diphosphate kinase from Mycobacterium tuberculosis.
Cytotoxic activity of nucleoside diphosphate kinase secreted from Mycobacterium tuberculosis.
Hydrogen/Deuterium Exchange Mass Spectrometry Reveals Mechanistic Details of Activation of Nucleoside Diphosphate Kinases by Oligomerization.
Intersubunit Ionic Interactions Stabilize the Nucleoside Diphosphate Kinase of Mycobacterium tuberculosis.
Mycobacterium tuberculosis nucleoside diphosphate kinase inactivates small GTPases leading to evasion of innate immunity.
Mycobacterium tuberculosis nucleoside diphosphate kinase shows interaction with putative ATP binding cassette (ABC) transporter, Rv1273c.
Nuclear localization and in situ DNA damage by Mycobacterium tuberculosis nucleoside-diphosphate kinase.
Nucleoside diphosphate kinase from Mycobacterium tuberculosis cleaves single strand DNA within the human c-myc promoter in an enzyme-catalyzed reaction.
Nucleoside diphosphate kinase of Mycobacterium tuberculosis acts as GTPase-activating protein for Rho-GTPases.
Structure of Mycobacterium tuberculosis nucleoside diphosphate kinase R80N mutant in complex with citrate.
Withdrawal: Nuclear localization and in situ DNA damage by Mycobacterium tuberculosis nucleoside-diphosphate kinase.
X-ray structure of Mycobacterium tuberculosis nucleoside diphosphate kinase.
Urinary Bladder Neoplasms
Analysis of nm23 gene expressions in human bladder and renal cancers.
Clinical significance of altered nm23-H1, EGFR, RB and p53 expression in bilharzial bladder cancer.
Immunohistochemical analysis of nm23-H1 protein in bladder cancer.
Nm23-H1 protein, DNA-ploidy and S-phase fraction in relation to overall survival and disease free survival in transitional cell carcinoma of the bladder.
The role of nm23-H1 in the progression of transitional cell bladder cancer.
[CD44v and nm23-H1 gene product expression and its clinical significance in human recurrent bladder cancer]
[The effects of nm23-H1 gene cell transfection on abilities of invasion, adhension and chemotherapeutic sensitivity of bladder cancer T-24 cell line]
Urologic Neoplasms
Expression of nm23-H1 in transitional cell carcinoma of the upper urinary tract.
Uterine Cervical Neoplasms
Clinical implication of voltage-dependent anion channel 1 in uterine cervical cancer and its action on cervical cancer cells.
Clinical significance of high nm23-H1 expression in intraepithelial neoplasia and early-stage squamous cell carcinoma of the uterine cervix.
Down-regulated nucleoside diphosphate kinase nm23-H1 expression is unrelated to high-risk human papillomavirus but associated with progression of cervical intraepithelial neoplasia and unfavourable prognosis in cervical cancer.
Expression of nm23-h1 gene in squamous-cell carcinoma of the cervix correlates with 5-year survival.
High expression of human nonmetastatic clone 23 type 1 in cancer of uterine cervix and its association with poor cell differentiation and worse overall survival.
Human nonmetastatic clone 23 type 1 gene suppresses migration of cervical cancer cells and enhances the migration inhibition of fungal immunomodulatory protein from Ganoderma tsugae.
Immunoreactivities of human nonmetastatic clone 23 and p53 products are disassociated and not good predictors of lymph node metastases in early-stage cervical cancer patients.
Implication of human nonmetastatic clone 23 Type 1 and its downstream gene lipocalin 2 in metastasis and patient's survival of cancer of uterine cervix.
Laparoscopic surgery inhibits the proliferation and metastasis of cervical cancer cells.
Nm23 expression in endometrial and cervical cancer: inverse correlation with lymph node involvement and myometrial invasion.
Nm23-H1: a metastasis-associated gene.
Predicting high-risk human papillomavirus infection, progression of cervical intraepithelial neoplasia, and prognosis of cervical cancer with a panel of 13 biomarkers tested in multivariate modeling.
[Effects of tumor metastasis suppressor gene nm23-H1 on invasion and proliferation of cervical cancer cell lines.]
[Relationship between nm23-H1 expression and lymph node metastasis and prognosis in cervical cancer]
[Ultrastructural immunocytochemical localization of diphosphate kinase/Nm23 in human cancer cells]
Vascular Diseases
Discovery of NM23-H2 as an estrogen receptor beta-associated protein: role in estrogen-induced gene transcription and cell migration.
Ventricular Dysfunction
Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure.
Vesicular Stomatitis
Nucleoside diphosphate kinase activity in purified cores of vesicular stomatitis virus.
Virus Diseases
Increased nucleoside diphosphate kinase activity induces white spot syndrome virus infection in Litopenaeus vannamei.
nm23-H1 protein immunoreactivity in intraepithelial neoplasia and invasive squamous cell carcinoma of the uterine cervix.
Warts
nm23-H1 protein immunoreactivity in intraepithelial neoplasia and invasive squamous cell carcinoma of the uterine cervix.
Whooping Cough
Activation of GTP formation and high-affinity GTP hydrolysis by mastoparan in various cell membranes. G-protein activation via nucleoside diphosphate kinase, a possible general mechanism of mastoparan action.