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2.7.4.6: nucleoside-diphosphate kinase

This is an abbreviated version!
For detailed information about nucleoside-diphosphate kinase, go to the full flat file.

Word Map on EC 2.7.4.6

Reaction

ATP
+
nucleoside diphosphate
=
ADP
+
nucleoside triphosphate

Synonyms

AfNDK, Afu5g03490, ASNDK, At4g09320, At4g11010, At5g63310, HsNDK, kinase, nucleoside diphosphate (phosphorylating), mitochondrial nucleoside diphosphate kinase, MJ1265, More, NDK, NDK B, NDK-1, NDKB, NDP kinase, NDP kinase A, NDP kinase alpha, NDP kinase beta, NDPK, NDPK B, NDPK I, NDPK II, NDPK III, NDPK IIpn, NDPK In, NDPK-3, NDPK-B, NDPK-C, NDPK-D, NDPK-In, NDPK1, NDPK2, NDPK3, NDPK3a, NDPKA, NDPKB, NM23, NM23 metastasis suppressor, Nm23-H1, NM23-H2, NM23-H4, NME1, NME2, NME3, NME4, nucleoside 5'-diphosphate kinase, nucleoside diphosphate (UDP) kinase, nucleoside diphosphate kinase, nucleoside diphosphate kinase 1, nucleoside diphosphate kinase 2, nucleoside diphosphate kinase 3, nucleoside diphosphate kinase 3a, nucleoside diphosphate kinase A, nucleoside diphosphate kinase B, nucleoside diphosphate kinase C, nucleoside diphosphate kinase D, nucleoside diphosphate kinase-1, nucleoside diphosphate kinase-2, nucleoside diphosphate kinases alpha, nucleoside diphosphate kinases beta, nucleoside diphosphate phosphotransferase, nucleoside diphosphokinase, nucleoside-diphosphate kinase 3, nucleotide diphosphate kinase, nucleotide phosphate kinase, ORF454, Os12g36194, OsNDPK2, SwoH, TcNDPK1, TcNDPK3, UDP kinase, uridine diphosphate kinase, WSL12, YSS2 protein

ECTree

     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.4 Phosphotransferases with a phosphate group as acceptor
                2.7.4.6 nucleoside-diphosphate kinase

Substrates Products

Substrates Products on EC 2.7.4.6 - nucleoside-diphosphate kinase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2',3'-dehydro-3'-deoxyTDP + ATP
2',3'-dehydro-3'-deoxyTTP + ADP
show the reaction diagram
-
-
-
?
3'-fluoro-2',3'-dideoxyUDP + ATP
3'-fluoro-2',3'-dideoxyUTP + ADP
show the reaction diagram
better than 2’,3’-dideoxyUDP, but much poorer than 2’-deoxyUDP
-
-
?
3'-fluoro-3'-deoxyTDP + ATP
3'-fluoro-3'-deoxyTTP + ADP
show the reaction diagram
-
-
-
?
ADP + ATP
ATP + ADP
show the reaction diagram
ADP + CTP
ATP + CDP
show the reaction diagram
ADP + dADP
AMP + dATP
show the reaction diagram
-
-
-
r
ADP + dCDP
AMP + dCTP
show the reaction diagram
low activity
-
-
r
ADP + dCTP
ATP + dCDP
show the reaction diagram
-
-
-
-
?
ADP + dGDP
AMP + dGTP
show the reaction diagram
-
-
-
r
ADP + dGTP
ATP + dGDP
show the reaction diagram
ADP + dTTP
ATP + dTDP
show the reaction diagram
-
-
-
-
?
ADP + dUTP
ATP + dUDP
show the reaction diagram
-
-
-
-
?
ADP + GTP
ATP + GDP
show the reaction diagram
ADP + ITP
ATP + IDP
show the reaction diagram
-
-
-
?
ADP + TTP
ATP + TDP
show the reaction diagram
ADP + UTP
ATP + UDP
show the reaction diagram
ATP + 8-bromo-IDP
ADP + ?
show the reaction diagram
ATP + 8-bromoinosine 5'-diphosphate
ADP + 8-bromoinosine 5'-triphosphate
show the reaction diagram
ATP + adenosine 5'-methylene diphosphonate
ADP + ?
show the reaction diagram
-
-
-
?
ATP + ADP
ADP + ATP
show the reaction diagram
ATP + CDP
ADP + CTP
show the reaction diagram
ATP + dADP
ADP + dATP
show the reaction diagram
ATP + dCDP
ADP + dCTP
show the reaction diagram
ATP + dGDP
ADP + dGTP
show the reaction diagram
ATP + dNDP
ADP + dNTP
show the reaction diagram
ATP + dTDP
ADP + dTTP
show the reaction diagram
ATP + dUDP
?
show the reaction diagram
ATP + dUDP
ADP + dUTP
show the reaction diagram
ATP + GDP
ADP + GTP
show the reaction diagram
ATP + NDP
ADP + NTP
show the reaction diagram
ATP + nucleoside diphosphate
ADP + nucleoside triphosphate
show the reaction diagram
ATP + TDP
ADP + TTP
show the reaction diagram
ATP + tubulin-GDP
ADP + tubulin-GTP
show the reaction diagram
-
-
-
?
ATP + UDP
ADP + UTP
show the reaction diagram
ATP + XDP
ADP + XTP
show the reaction diagram
-
reaction at 37% the rate of UDP
-
-
?
CTP + ADP
CDP + ATP
show the reaction diagram
-
-
-
?
CTP + CDP
CDP + CTP
show the reaction diagram
dATP + ADP
dADP + ATP
show the reaction diagram
dATP + CDP
dADP + CTP
show the reaction diagram
-
-
-
r
dATP + GDP
dADP + GTP
show the reaction diagram
-
-
-
?
dATP + IDP
dADP + ITP
show the reaction diagram
-
-
-
?
dATP + UDP
dADP + UTP
show the reaction diagram
-
-
-
?
dCTP + ADP
dCDP + ATP
show the reaction diagram
dGDP + ATP
dGTP + ADP
show the reaction diagram
-
-
-
-
?
dGTP + ADP
dGDP + ATP
show the reaction diagram
dTTP + ADP
dTDP + ATP
show the reaction diagram
gamma-S-ATP + GDP
ADP + gamma-S-GTP
show the reaction diagram
gamma-S-GTP + GDP
GDP + gamma-S-GTP
show the reaction diagram
GDP + ATP
GTP + ADP
show the reaction diagram
-
-
-
?
GTP + ADP
GDP + ATP
show the reaction diagram
GTP + CDP
GDP + CTP
show the reaction diagram
GTP + dGDP
GDP + dGTP
show the reaction diagram
-
-
-
-
?
GTP + dTDP
GDP + dTTP
show the reaction diagram
-
-
-
-
?
GTP + GDP
GDP + GTP
show the reaction diagram
GTP + NDP
GDP + NTP
show the reaction diagram
GTP + nucleoside diphosphate
GDP + nucleoside triphosphate
show the reaction diagram
GTP + UDP
GDP + UTP
show the reaction diagram
GTP-bound Ras protein + NDP
GDP-bound Ras protein + NTP
show the reaction diagram
-
in vitro, inactivation of mutant oncogenic Ras proteins
-
-
?
ITP + ADP
IDP + ATP
show the reaction diagram
ITP + UDP
IDP + UTP
show the reaction diagram
-
-
-
-
?
NDP + NTP
NTP + NDP
show the reaction diagram
NTP + ADP
NDP + ATP
show the reaction diagram
-
-
-
?
NTP + NDP
NDP + NTP
show the reaction diagram
NTP + nucleoside diphosphate
NDP + NTP
show the reaction diagram
TTP + ADP
TDP + ATP
show the reaction diagram
-
-
-
?
tubulin-GDP-complex + ATP
tubulin-GTP-complex + ADP
show the reaction diagram
-
-
-
-
?
UTP + ADP
UDP + ATP
show the reaction diagram
-
-
-
?
UTP + CDP
UDP + CTP
show the reaction diagram
UTP + dCDP
UDP + dCTP
show the reaction diagram
UTP + dTDP
UDP + dTDP
show the reaction diagram
UTP + UDP
UDP + UTP
show the reaction diagram
-
reaction at 31% the rate of ATP
-
?
additional information
?
-