2.7.4.6: nucleoside-diphosphate kinase

This is an abbreviated version!
For detailed information about nucleoside-diphosphate kinase, go to the full flat file.

Reaction

Synonyms

AfNDK, Afu5g03490, ASNDK, At4g09320, At4g11010, At5g63310, HsNDK, kinase, nucleoside diphosphate (phosphorylating), mitochondrial nucleoside diphosphate kinase, MJ1265, More, NDK, NDK B, NDK-1, NDKB, NDP kinase, NDP kinase A, NDP kinase alpha, NDP kinase beta, NDPK, NDPK B, NDPK I, NDPK II, NDPK III, NDPK IIpn, NDPK In, NDPK-3, NDPK-B, NDPK-C, NDPK-D, NDPK-In, NDPK1, NDPK2, NDPK3, NDPK3a, NDPKA, NDPKB, NM23, NM23 metastasis suppressor, Nm23-H1, NM23-H2, NM23-H4, NME1, NME2, NME3, NME4, nucleoside 5'-diphosphate kinase, nucleoside diphosphate (UDP) kinase, nucleoside diphosphate kinase, nucleoside diphosphate kinase 1, nucleoside diphosphate kinase 2, nucleoside diphosphate kinase 3, nucleoside diphosphate kinase 3a, nucleoside diphosphate kinase A, nucleoside diphosphate kinase B, nucleoside diphosphate kinase C, nucleoside diphosphate kinase D, nucleoside diphosphate kinase-1, nucleoside diphosphate kinase-2, nucleoside diphosphate kinases alpha, nucleoside diphosphate kinases beta, nucleoside diphosphate phosphotransferase, nucleoside diphosphokinase, nucleoside-diphosphate kinase 3, nucleotide diphosphate kinase, nucleotide phosphate kinase, ORF454, Os12g36194, OsNDPK2, SwoH, TcNDPK1, TcNDPK3, UDP kinase, uridine diphosphate kinase, WSL12, YSS2 protein

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.4 Phosphotransferases with a phosphate group as acceptor

                2.7.4.6 nucleoside-diphosphate kinase

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Results	in table
6	Activating Compound
51439	AA Sequence
6	Application
1	CAS Registry Number
97	Cloned(Commentary)
24	Cofactor
42	Crystallization (Commentary)
5761	Disease/ Diagnostics
7	Expression
56	General Information
12	General Stability
7	IC50 Value
46	Inhibitors
26	kcat/KM [mM/s]
1	Ki Value [mM]
136	KM Value [mM]
121	Localization
167	Metals/Ions
148	Molecular Weight [Da]
124	Natural Substrates/ Products (Substrates)
966	Organism
28	Pathway
770	PDB ID
61	pH Optimum
4	pH Range
7	pH Stability
19	pI Value
17	Posttranslational Modification
139	Protein Variants
92	Purification (Commentary)
26	Reaction
1	Reaction Type
283	Reference
8	Renatured (Commentary)
238	Source Tissue
79	Specific Activity [micromol/min/mg]
8	Storage Stability
725	Substrates and Products (Substrate)
186	Subunits
322	Synonyms
1	Systematic Name
39	Temperature Optimum [°C]
4	Temperature Range [°C]
46	Temperature Stability [°C]
29	Turnover Number [1/s]

pH Stability

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of the Enzyme Summary Page.

pH Stability on EC 2.7.4.6 - nucleoside-diphosphate kinase

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pH STABILITY

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

3.5

Azumapecten farreri

A2TLM3

below, inactivation

691029

4 - 9

Oryza sativa

-

isozyme NDPK3

721870

5

Bos taurus

-

inactivation below

642637

6 - 8

Rattus norvegicus

-

the rate of the enzyme solubilization is dependent on the pH of the storage medium (pH 6.0-8.0), it decreases with increase in pH

702391

6 - 9

Oryza sativa

-

isozyme NDPK2

721870

7 - 9

Oryza sativa

-

isozyme NDPK1

721870

7.5 - 9

Plasmodium falciparum

-

the activity markedly drops as pH exceeds 7.8, about 25% relative activity at pH8.0-9.0

702511