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2.5.1.61: hydroxymethylbilane synthase

This is an abbreviated version!
For detailed information about hydroxymethylbilane synthase, go to the full flat file.

Word Map on EC 2.5.1.61

Reaction

4 porphobilinogen +

H2O
=
Hydroxymethylbilane
 + 4 NH3

Synonyms

(HMB)-synthase, AN0121.3, EC 4.3.1.8, HemC, hepatic porphobilinogen deaminase, HMB synthase, HMB-S, HMBS, HMBS1a-synthase, HMBS1b-synthase, HMBS2a-synthase, HMBS2b-synthase, human non-erythropoietic PBGD isoform, human PBGD, human porphobilinogen deaminase, hydroxymethylbilane synthase, More, PBG deaminase, PBG-D, PBG-deaminase, PBGD, PGB-D, porphobilinogen ammonia-lyase (polymerizing), porphobilinogen deaminase, pre-uroporphyrinogen synthase, preuroporphyrinogen synthase, preuroporphyrinogen synthetase, synthase, uroporphyrinogen I, uPBGD, UPGI-S, URO-S, urogenI synthase, uroporphyrinogen I synthase, uroporphyrinogen I synthetase, uroporphyrinogen synthase, uroporphyrinogen synthetase

ECTree

     2 Transferases
         2.5 Transferring alkyl or aryl groups, other than methyl groups
             2.5.1 Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
                2.5.1.61 hydroxymethylbilane synthase

Synonyms

Synonyms on EC 2.5.1.61 - hydroxymethylbilane synthase

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SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
(HMB)-synthase
-
-
EC 4.3.1.8
hepatic porphobilinogen deaminase
HMB-S
HMBS1a-synthase
housekeeping, GenBank GQ850461, isolated from liver
HMBS1b-synthase
housekeeping, truncated form, GenBank GQ850462, isolated from liver
HMBS2a-synthase
erythroid-specific, GenBank GQ850463, isolated from spleen
HMBS2b-synthase
erythroid-specific, GenBank GQ850464, isolated from spleen
human non-erythropoietic PBGD isoform
-
human PBGD
-
human porphobilinogen deaminase
-
hydroxymethylbilane synthase
PBG deaminase
PBG-D
PBG-deaminase
porphobilinogen ammonia-lyase (polymerizing)
-
-
-
-
porphobilinogen deaminase
pre-uroporphyrinogen synthase
-
-
-
-
preuroporphyrinogen synthase
-
preuroporphyrinogen synthetase
synthase, uroporphyrinogen I
-
-
-
-
uPBGD
ubiquitous PBGD, espressed in all cells
UPGI-S
urogenI synthase
-
-
uroporphyrinogen I synthase
uroporphyrinogen I synthetase
uroporphyrinogen synthase
-
-
-
-
uroporphyrinogen synthetase
additional information