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Literature summary for 2.5.1.61 extracted from
- Biosynthesis of the pigments of life: formation of the macrocycle (1980), Nature, 285, 17-19.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| porphobilinogen | Gallus gallus | - |
? | - |
? |  |
| porphobilinogen | Euglena gracilis | - |
? | - |
? | |
| porphobilinogen | Propionibacterium freudenreichii subsp. shermanii | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Euglena gracilis | - |
- |
- |
| Gallus gallus | - |
- |
- |
| Propionibacterium freudenreichii subsp. shermanii | - |
- |
- |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| 4 porphobilinogen + H2O = hydroxymethylbilane + 4 NH3 | mechanism | Gallus gallus | |
| 4 porphobilinogen + H2O = hydroxymethylbilane + 4 NH3 | mechanism | Euglena gracilis | |
| 4 porphobilinogen + H2O = hydroxymethylbilane + 4 NH3 | mechanism | Propionibacterium freudenreichii subsp. shermanii |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4 porphobilinogen | in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 | Gallus gallus | uroporphyrinogen III + 4 NH3 | - |
? | |
| 4 porphobilinogen | in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 | Euglena gracilis | uroporphyrinogen III + 4 NH3 | - |
? | |
| 4 porphobilinogen | in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 | Propionibacterium freudenreichii subsp. shermanii | uroporphyrinogen III + 4 NH3 | - |
? | |
| 4 porphobilinogen + H2O | - |
Gallus gallus | hydroxylmethylbilane + 4 NH3 | - |
? | |
| 4 porphobilinogen + H2O | - |
Euglena gracilis | hydroxylmethylbilane + 4 NH3 | - |
? | |
| 4 porphobilinogen + H2O | - |
Propionibacterium freudenreichii subsp. shermanii | hydroxylmethylbilane + 4 NH3 | - |
? | |
| porphobilinogen | - |
Gallus gallus | ? | - |
? | |
| porphobilinogen | - |
Euglena gracilis | ? | - |
? | |
| porphobilinogen | - |
Propionibacterium freudenreichii subsp. shermanii | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| PBG-deaminase | - |
Gallus gallus |
| PBG-deaminase | - |
Euglena gracilis |
| PBG-deaminase | - |
Propionibacterium freudenreichii subsp. shermanii |
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