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4 porphobilinogen
uroporphyrinogen III + 4 NH3
4 porphobilinogen + H2O
1-hydroxymethylbilane + 4 NH3
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
additional information
?
-
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
uroporphyrinogen III cosynthase is more heat-labile than porphobilinogen deaminase. Heat-treatment of the porphobilinogen deaminase/uroporphyrinogen III cosynthase enzyme system forms only 2-4% of uroporphyrinogen III
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
-
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen
uroporphyrinogen III + 4 NH3
-
in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75
-
?
4 porphobilinogen + H2O
1-hydroxymethylbilane + 4 NH3
-
third reaction step in heme biosynthesis pathway
-
-
?
4 porphobilinogen + H2O
1-hydroxymethylbilane + 4 NH3
-
polymerization of 4 pyrrole molecules to a linear tetrapyrrole
i.e. pre-uroporphyrinogen, highly unstable compound
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
1-hydroxymethylbilane, highly unstable
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
at pH 8.2, uroporphyrinogen I
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
uroporphyrinogen I
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
at pH 8.2, uroporphyrinogen I
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
uroporphyrinogen I
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
uroporphyrinogen I
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
stoichiometry of enzyme reaction
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
HMB
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
PBG
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
uroporphyrinogen I, uroporphyrinogen
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
uroporphyrinogen
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxylmethylbilane + 4 NH3
-
PBG
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
-
-
-
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
-
-
-
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
-
-
-
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
-
-
-
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
-
polymerization of 4 pyrrole molecules to a linear tetrapyrrole
i.e. pre-uroporphyrinogen, highly unstable compound
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
-
enzyme defects are involved in acute intermittent porphyria, AIP
-
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
-
enzyme defects are involved in acute intermittent porphyria, AIP, a neuropathic disease
-
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
-
the enzyme is important in heme biosynthesis, a nonsense mutation in the porphobilinogen deaminase gene causes acute intermittent porphyria, AIP, overview, eight enzymes are involved in the heme synthesis and defects in seven of them cause porphyria, overview
-
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
the enzyme is important in heme biosynthesis, a nonsense mutation in the porphobilinogen deaminase gene causes chester porphyria, existence of dual porphyrias with two enzymes of heme biosynthesis being deficient simultaneously, overview
-
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
-
third step in the heme biosynthetic pathway, enzyme defects are involved in acute intermittent porphyria, AIP, an autosomal dominant disorder characterised by acute, potentially life-threatening neurological attacks that are precipitated by various drugs, reproductive hormones and other factors
-
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
-
-
-
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
-
-
-
?
4 porphobilinogen + H2O
hydroxymethylbilane + 4 NH3
-
-
-
-
?
porphobilinogen
?
-
-
-
-
?
porphobilinogen
?
-
-
-
-
?
porphobilinogen
?
-
-
-
-
?
porphobilinogen
?
-
-
-
-
?
porphobilinogen
?
-
-
-
-
?
porphobilinogen
?
-
-
-
-
?
porphobilinogen
?
-
-
-
-
?
porphobilinogen
?
-
-
-
-
?
porphobilinogen
?
-
-
-
-
?
porphobilinogen
?
-
-
-
-
?
porphobilinogen
?
-
-
-
-
?
porphobilinogen
?
-
-
5882, 5883, 489925, 489926, 489935, 489938, 489941, 489942, 489943, 489945, 489948, 489951 -
-
?
porphobilinogen
?
-
-
-
-
?
porphobilinogen
?
-
-
-
-
?
porphobilinogen
?
-
-
-
-
?
porphobilinogen
?
-
-
-
-
?
porphobilinogen
?
-
-
-
-
?
porphobilinogen
?
-
-
-
-
?
porphobilinogen
?
-
-
-
-
?
porphobilinogen
?
-
-
-
-
?
porphobilinogen
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additional information
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third enzyme in the heme biosynthetic pathway
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in presence of a second enzyme, EC 4.2.1.75, uroporphyrinogen-III synthase, often called co-synthase, the product is cyclized to form uroporphyrinogen-III
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enzyme from chloroplasts is a nuclear-encoded protein, contains a transit-peptide part for transport across the organelle membrans
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additional information
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third enzyme in the heme biosynthetic pathway
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additional information
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third enzyme in the heme biosynthetic pathway
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additional information
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third enzyme in the heme biosynthetic pathway
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additional information
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third enzyme in the heme biosynthetic pathway
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additional information
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occurrence of multiple forms of the enzyme. These isomers correspond to the enzyme-substrate intermediates: mono-, di-, tri-, and tetrapyrrole
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mutations of the residues R167, R173, R149, and D99 of the enzyme cause acute intermittent porphyria, overview
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recurrent mutations G111R and R173Q occurring at CpG motifs of the enzyme cause acute intermittent porphyria AIP, a disorder of the heme biosynthetic pathway, oerview
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safety, pharmacokinetics and pharmacodynamics of recombinant human porphobilinogen deaminase P 9808, administered to healthy subjects and asymptomatic porphobilinogen deaminase-deficient subjects with high concentrations of porphobilinogen, the substrate of porphobilinogen deaminase for investigation and establishing of an alternative therapy of acute intermittent porphyria, AIP, method, overview
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the enzyme is also active in uroporphyrinogen formation from porphobilinogen, cf. EC 4.2.1.75
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enzyme-intermediates with increasing number of porphobilinogen molecules are formed during the catalysis of enzyme HMBS
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additional information
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third enzyme in the heme biosynthetic pathway
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additional information
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third enzyme in the heme biosynthetic pathway
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