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Literature summary for 2.5.1.61 extracted from

  • Brown, R.C.; Elder, G.H.; Urquhart, A.J.
    Purification of hydroxymethylbilane synthase from human erythrocytes (1985), Biochem. Soc. Trans., 13, 1227-1228.
No PubMed abstract available

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Homo sapiens 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
porphobilinogen Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4 porphobilinogen in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 Homo sapiens uroporphyrinogen III + 4 NH3
-
?
4 porphobilinogen + H2O
-
Homo sapiens hydroxylmethylbilane + 4 NH3 HMB ?
porphobilinogen
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
(HMB)-synthase
-
Homo sapiens
porphobilinogen deaminase
-
Homo sapiens