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Literature summary for 2.5.1.61 extracted from

  • Sharif, A.; Smith, A.G.; Abell, C.
    Isolation and characterisation of cDNA clone for chlorophyll synthesis enzyme from Euglena gracilis (1989), Eur. J. Biochem., 184, 353-359.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Euglena gracilis

Localization

Localization Comment Organism GeneOntology No. Textmining
chloroplast
-
Euglena gracilis 9507
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
36927
-
1 * 36927, calculation from sequence of cDNA Euglena gracilis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens third enzyme in the heme biosynthetic pathway ?
-
?
additional information Rattus norvegicus third enzyme in the heme biosynthetic pathway ?
-
?
additional information Euglena gracilis third enzyme in the heme biosynthetic pathway ?
-
?
additional information Euglena gracilis enzyme from chloroplasts is a nuclear-encoded protein, contains a transit-peptide part for transport across the organelle membrans ?
-
?
porphobilinogen Escherichia coli
-
?
-
?
porphobilinogen Homo sapiens
-
?
-
?
porphobilinogen Rattus norvegicus
-
?
-
?
porphobilinogen Euglena gracilis
-
?
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Euglena gracilis
-
-
-
Homo sapiens
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4 porphobilinogen in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 Escherichia coli uroporphyrinogen III + 4 NH3
-
?
4 porphobilinogen in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 Homo sapiens uroporphyrinogen III + 4 NH3
-
?
4 porphobilinogen in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 Rattus norvegicus uroporphyrinogen III + 4 NH3
-
?
4 porphobilinogen in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 Euglena gracilis uroporphyrinogen III + 4 NH3
-
?
4 porphobilinogen + H2O
-
Escherichia coli hydroxylmethylbilane + 4 NH3
-
?
4 porphobilinogen + H2O
-
Homo sapiens hydroxylmethylbilane + 4 NH3
-
?
4 porphobilinogen + H2O
-
Rattus norvegicus hydroxylmethylbilane + 4 NH3
-
?
4 porphobilinogen + H2O
-
Euglena gracilis hydroxylmethylbilane + 4 NH3
-
?
additional information third enzyme in the heme biosynthetic pathway Homo sapiens ?
-
?
additional information third enzyme in the heme biosynthetic pathway Rattus norvegicus ?
-
?
additional information third enzyme in the heme biosynthetic pathway Euglena gracilis ?
-
?
additional information enzyme from chloroplasts is a nuclear-encoded protein, contains a transit-peptide part for transport across the organelle membrans Euglena gracilis ?
-
?
porphobilinogen
-
Escherichia coli ?
-
?
porphobilinogen
-
Homo sapiens ?
-
?
porphobilinogen
-
Rattus norvegicus ?
-
?
porphobilinogen
-
Euglena gracilis ?
-
?

Subunits

Subunits Comment Organism
monomer
-
Escherichia coli
monomer
-
Homo sapiens
monomer
-
Rattus norvegicus
monomer 1 * 36927, calculation from sequence of cDNA Euglena gracilis

Synonyms

Synonyms Comment Organism
HMBS
-
Escherichia coli
porphobilinogen deaminase
-
Escherichia coli
porphobilinogen deaminase
-
Homo sapiens
porphobilinogen deaminase
-
Rattus norvegicus
porphobilinogen deaminase
-
Euglena gracilis