2.3.2.13: protein-glutamine gamma-glutamyltransferase

This is an abbreviated version!
For detailed information about protein-glutamine gamma-glutamyltransferase, go to the full flat file.

Reaction

Synonyms

AcTG-1, BmTGA, chloroplast transglutaminase, chlTGase, cold active transglutaminase, cold-active transglutaminase, EPB42, factor XIII, factor XIIIa, fibrin stabilizing factor, fibrinoligase, Galphah, glutamine:amine gamma-glutamyl-transferase, glutaminylpeptide gamma-glutamyltransferase, glutamyltransferase, glutaminylpeptide gamma-, gpTGase 2, gTG2, hfXIIIa, hTG2, hTGase 1, hTGase 2, hTGase 3, hTGase 6, KALB, KalbTG, KALB_7456, Laki-Lorand factor, mammalian transglutaminase, microbial transglutaminase, microbial transglutaminases, MsTGase, MTG, MTG-TX, MTGase, mTGase 2, OlTGT, plastidial transglutaminase, polyamine transglutaminase, protein 4.2, protein-glutamine gamma-glutamyltransferase, R-glutaminyl-peptide:amine gamma-glutamyl transferase, R-glutaminylpeptide-amine gamma-glutamyltransferase, SCTG, SMTG, STG I, t-TG, TG-2, TG1, TG2, TG3, TG4, TG5, TG6, TG7, tGA, TGase, TGase 1, TGase 2, Tgase 3, TGase 6, Tgase II, TGase-2, TGase2, TGB, TGK1, TGK2, TGL, TGM1, TGM2, TGM3, TGM4, TGM5, TGM6, TGM7, TGZ, tgz15, TGZo, tissue transglutaminase, tissue transglutaminase 2, tissue-TG, transglutaminase, transglutaminase 1, transglutaminase 2, transglutaminase 3, transglutaminase 6, transglutaminase C, transglutaminase factor XIII, transglutaminase type II, transglutaminase-2, transglutaminase-like protein, transglutaminase2, tTG, tTG-2, type 2 transglutaminase, type I transglutaminase, type-2 transglutaminase

ECTree

     2 Transferases

         2.3 Acyltransferases

             2.3.2 Aminoacyltransferases

                2.3.2.13 protein-glutamine gamma-glutamyltransferase

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Results	in table
53	Activating Compound
1511	AA Sequence
60	Application
1	CAS Registry Number
72	Cloned(Commentary)
2	Cofactor
16	Crystallization (Commentary)
14096	Disease/ Diagnostics
11	Expression
108	General Information
21	General Stability
237	IC50 Value
865	Inhibitors
20	kcat/KM [mM/s]
151	Ki Value [mM]
133	KM Value [mM]
108	Localization
170	Metals/Ions
108	Molecular Weight [Da]
159	Natural Substrates/ Products (Substrates)
8	Organic Solvent Stability
467	Organism
1	Oxidation Stability
73	PDB ID
58	pH Optimum
12	pH Range
14	pH Stability
4	pI Value
33	Posttranslational Modification
189	Protein Variants
98	Purification (Commentary)
24	Reaction
1	Reaction Type
322	Reference
1	Renatured (Commentary)
361	Source Tissue
88	Specific Activity [micromol/min/mg]
25	Storage Stability
602	Substrates and Products (Substrate)
100	Subunits
392	Synonyms
1	Systematic Name
65	Temperature Optimum [°C]
11	Temperature Range [°C]
40	Temperature Stability [°C]
49	Turnover Number [1/s]

Cofactor

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Cofactor on EC 2.3.2.13 - protein-glutamine gamma-glutamyltransferase

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COFACTOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

ERp57

Homo sapiens

P21980

TG2 cofactors TRX and ERp57 reversibly regulate TG2 in a redox-dependent manner, and act as on and off switches for the active enzyme

758635

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thioredoxin

Homo sapiens

P21980

TRX, TG2 cofactors TRX and ERp57 reversibly regulate TG2 in a redox-dependent manner, and act as on and off switches for the active enzyme

758635