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Information on EC 3.1.4.54 - N-acetylphosphatidylethanolamine-hydrolysing phospholipase D

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IUBMB Comments
This enzyme is involved in the biosynthesis of anandamide. It does not hydrolyse phosphatidylcholine and phosphatidylethanolamine . No transphosphatidation . The enzyme contains Zn2+ and is activated by Mg2+ or Ca2+ .
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
anandamide-generating phospholipase D, N-acyl phosphatidylethanolamine phospholipase D, N-acyl-phosphatidylethanolamine-specific phospholipase D, N-acylphosphatidylethanolamine-specific phospholipase D, NAPE-hydrolysing phospholipase D, NAPE-PLD, NAPEPLD, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
N-acylphosphatidylethanolamine + H2O = N-acylethanolamine + a 1,2-diacylglycerol 3-phosphate
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