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Literature summary for 3.1.4.54 extracted from

  • Hegyi, Z.; Hollo, K.; Kis, G.; Mackie, K.; Antal, M.
    Differential distribution of diacylglycerol lipase-alpha and N-acylphosphatidylethanolamine-specific phospholipase d immunoreactivity in the superficial spinal dorsal horn of rats (2012), Glia, 60, 1316-1329.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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Source Tissue

Source Tissue Comment Organism Textmining
glial cell a substantial proportion of astrocytic and microglial profiles are immunolabeled for both diacylglycerol lipase alpha and NAPE-PLD. NAPE-PLD immunoreactivity on glial profiles at the vicinity of synapses is only occasionally observed. Results suggest that both neurons and glial cells can synthesize and release anandamide in the superficial spinal dorsal horn. Anandamide can predominantly be released from nonsynaptic dendritic and glial compartments Rattus norvegicus
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neuron dendritic labeling of N-acylphosphatidylethanolamine-specific phospholipase NAPE-PLD is never observed in association with synaptic contacts. In addition to dendrites, a substantial proportion of astrocytic and microglial profiles are also immunolabeled for both diacylglycerol lipase alpha and NAPE-PLD. NAPE-PLD immunoreactivity on glial profiles at the vicinity of synapses is only occasionally observed. Results suggest that both neurons and glial cells can synthesize and release anandamide in the superficial spinal dorsal horn. Anandamide can predominantly be released from nonsynaptic dendritic and glial compartments Rattus norvegicus
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Synonyms

Synonyms Comment Organism
NAPE-PLD
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Rattus norvegicus