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Literature summary for 3.1.4.54 extracted from

  • Nyilas, R.; Dudok, B.; Urbán, G.M.; Mackie, K.; Watanabe, M.; Cravatt, B.F.; Freund, T.F.; Katona, I.
    Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals (2008), J. Neurosci., 28, 1058-1063.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
N-acylphosphatidylethanolamine + H2O Mus musculus biosynthetic enzyme of anandamide and its related bioactive congeners, the N-acylethanolamines N-acylethanolamine + phosphatidate
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Organism

Organism UniProt Comment Textmining
Mus musculus Q8BH82
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Source Tissue

Source Tissue Comment Organism Textmining
brain the enzyme concentrated presynaptically in several types of hippocampal excitatory axon terminals. Localized predominantly on the intracellular membrane cisternae of axonal calcium stores. The highest density of NAPE-PLD is found in mossy terminals of granule cells, which do not express CB1 receptors Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-acylphosphatidylethanolamine + H2O biosynthetic enzyme of anandamide and its related bioactive congeners, the N-acylethanolamines Mus musculus N-acylethanolamine + phosphatidate
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?

Synonyms

Synonyms Comment Organism
NAPE-PLD
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Mus musculus