Reference on EC 2.7.7.19 - polynucleotide adenylyltransferase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Mans, K.J.; Walter, T.J.
Transfer RNA-primed oligoadenylate synthesis in maize seedlings. II. Primer, substrate and metal specificities and size of product
Biochim. Biophys. Acta
247
113-121
1971
Rattus norvegicus, Zea mays
Bollum, F.J.; Chang, L.M.S.; Tsiapalis, C.M.; Dorson, J.W.
Nucleotide polymerizing enzymes from calf thymus gland
Methods Enzymol.
29E
70-81
1974
Bos taurus
-
Edmonds, M.
Poly(A) adding enzymes
The Enzymes,3rd Ed. (Boyer,P. D. ,ed. )
15
217-244
1982
Bos taurus, Cricetulus griseus, Coturnix sp., Escherichia coli, Homo sapiens, Mus musculus, Rattus norvegicus, Vaccinia virus
-
Tarui, Y.; Minamikawa, T.
Purification and properties of poly(A) polymerase from Vigna unguiculata
Plant Cell Physiol.
29
835-842
1988
Vigna unguiculata
-
Winters, M.A.; Edmonds, M.
A poly(A) polymerase from calf thymus. Purification and properities of the enzyme
J. Biol. Chem.
248
4756-4762
1973
Bos taurus
Winters, M.A.; Edmonds, M.
A poly(A) polymerase from calf thymus. Characterization of the reaction product and the primer requirement
J. Biol. Chem.
248
4763-4768
1973
Bos taurus
Raabe, T.; Bollum, F.J.; Manley, J.L.
Primary structure and expression of bovine poly(A) polymerase
Nature
353
229-234
1991
Bos taurus
Moss, B.; Rosenblum, E.N.; Gershowitz, A.
Characterization of a polyriboadenylate polymerase from vaccinia virions
J. Biol. Chem.
250
4722-4729
1975
Vaccinia virus
Tsiapalis, C.M.; Dorson, J.W.; Bollum, F.J.
Purification of terminal riboadenylate transferase from calf thymus gland
J. Biol. Chem.
250
4486-4496
1975
Bos taurus
Wahle, E.; Martin, G.; Schiltz, E.; Keller, W.
Isolation and expression of cDNA clones encoding mammalian poly(A) polymerase
EMBO J.
10
4251-4257
1991
Bos taurus
Rose, K.M.; Jacob, S.T.
Nuclear poly(A) polymerase from rat liver and a hepatoma. Comparison of properties, molecular weights and amino acid compositions
Eur. J. Biochem.
67
11-21
1976
Rattus norvegicus
Nevins, J.R.; Joklik, W.K.
Isolation and partial characterization of the poly(A) polymerases from HeLa cells infected with vaccinia virus
J. Biol. Chem.
252
6939-6947
1977
Homo sapiens, Vaccinia virus
Ueyama, H.
Characterization of polyriboadenylate polymerase from Tetrahymena pyriformis
J. Biochem.
86
1301-1311
1979
Tetrahymena pyriformis
Cheung, K.K.; Newton, A.
Polyadenylic acid synthesis activity of purified DNA-dependent RNA polymerase from Caulobacter
J. Biol. Chem.
253
2254-2261
1978
Caulobacter vibrioides, Caulobacter vibrioides CB15
Abraham, A.K.; Jacob, S.T.
Hydrolysis of poly (A) to adenine nucleotides by purified poly (A) polymerase
Proc. Natl. Acad. Sci. USA
75
2085-2087
1978
Rattus norvegicus
Rose, K.M.; Morris, H.P.; Jacob, S.T.
Mitochondrial poly(A) polymerase from a poorly differentiated hepatoma: purification and characteristics
Biochemistry
14
1025-1032
1975
Rattus norvegicus
Kurl, R.N.; Holmes, S.C.; Verney, E.; Sidransky, H.
Nuclear envelope glycoprotein with poly(A) polymerase activity of rat liver: isolation, characterization, and immunohistochemical localization
Biochemistry
27
8974-8980
1988
Rattus norvegicus
Pellicer, A.; Salas, J.; Salas, M.L.
Characterization of two poly(A) polymerases from cultured hamster fibroblasts
Biochim. Biophys. Acta
519
149-162
1978
Mesocricetus auratus
Roggen, E.; Slegers, H.
Isolation and characterization of cytoplasmic poly(A) polymerase from cryptobiotic gastrulae of Artemia salina
Eur. J. Biochem.
147
225-232
1985
Artemia salina
Ryner, L.C.; Takagaki, Y.; Manley, J.L.
Multiple forms of poly(A) polymerases purified from HeLa cells function in specific mRNA 3-end formation
Mol. Cell. Biol.
9
4229-4238
1989
Homo sapiens
Sippel, A.E.
Purification and characterization of adenosine triphosphate: ribonucleic acid adenyltransferase from Escherichia coli
Eur. J. Biochem.
37
31-40
1973
Escherichia coli
Wahle, E.
Purification and characterization of a mammalian polyadenylate polymerase involved in the 3 end processing of messenger RNA precursors
J. Biol. Chem.
266
3131-3139
1991
Bos taurus
Lingner, J.; Radtke, I.; Wahle, E.; Keller, W.
Purification and characterization of poly(A) polymerase from Saccharomyces cerevisiae
J. Biol. Chem.
266
8741-8746
1991
Saccharomyces cerevisiae
Takagaki, Y.; Ryner, L.C.; Manley, J.L.
Separation and characterization of a poly(A) polymerase and a cleavage/specificity factor required for pre-mRNA polyadenylation
Cell
52
731-742
1988
Homo sapiens
Christofori, G.; Keller, W.
Poly(A) polymerase purified from HeLa cell nuclear extract is required for both cleavage and polyadenylation of pre-mRNA in vitro
Mol. Cell. Biol.
9
193-203
1989
Homo sapiens
Kapoor, R.; Verma, N.; Saluja, D.; Lakhani, S.; Sachar, R.C.
Purification and characterization of poly(A) polymerase from germinated wheat embryos: enzyme glycosylation
Plant Sci.
89
167-176
1993
Triticum aestivum
-
Saluja, D.; Mathur, M.; Sachar, R.C.
Purification of poly(A) polymerase from mung bean hypocotyls: subunit structure, molecular properties and characterization of the reaction product
Plant Sci.
60
27-38
1989
Vigna radiata
-
Sastre, L.; Sebastian, J.
Purification and properties of a polyadenylate polymerase from Artemia dormant embryos
Biochim. Biophys. Acta
661
54-62
1981
Artemia sp.
-
Antoniades, D.; Antonoglou, O.
Poly(A) polymerases of rat liver nuclei. Purification and specificity
Biochim. Biophys. Acta
519
447-460
1978
Rattus norvegicus
Jacob, S.T.; Rose, K.M.
Inhibition of poly(A) polymerase by rifamycin derivatives
Nucleic Acids Res.
1
1549-1559
1974
Rattus norvegicus
Blakesley, R.W.; Boezi, J.A.
A kinetic and structural characterization of adenosine-5-triphosphate: ribonucleic acid adenylyltransferase from Pseudomonas putida
Biochim. Biophys. Acta
414
133-145
1975
Homo sapiens, Pseudomonas putida
Jacob, S.T.; Rose, K.M.; Morris, H.P.
Expression of purified mitochondrial poly(A)polymerase of hepatomas by an endogenous primer from liver.
Biochim. Biophys. Acta
361
312-320
1974
Rattus norvegicus
Rose, K.M.; Jacob, S.T.
Inhibition of the polyadenylation reaction in vitro by polyamines
Arch. Biochem. Biophys.
175
748-753
1976
Rattus norvegicus
Brakel, C.; Kates, J.R.
Poly(A) polymerase from vaccinia virus-infected cells. I. Partial purification and characterization
J. Virol.
14
715-723
1974
Homo sapiens
Ohyama, Y.; Fukami, H.; Ohta, T.
Purification and characterization of a poly(A) polymerase from beef liver nuclei
J. Biochem.
88
337-348
1980
Bos taurus
Koch, S.; Niessing, J.
Mode of inhibition of nuclear poly(A)polymerase by 2-dATP and 3-dATP
FEBS Lett.
96
354-356
1978
Rattus norvegicus
Martin, G.; Keller, W.; Doublie, S.
Crystal structure of mammalian poly(A) polymerase in complex with an analog of ATP
EMBO J.
19
4193-4203
2000
Bos taurus (P25500), Bos taurus
Bard, J.; Zhelkovsky, A.M.; Helmling, S.; Earnest, T.N.; Moore, C.L.; Bohm, A.
Structure of yeast poly(A) polymerase alone and in complex with 3'-dATP
Science
289
1346-1349
2000
Saccharomyces cerevisiae
Raynal, L.C.; Krisch, H.M.; Carpousis, A.J.
Bacterial poly(A) polymerase: an enzyme that modulates RNA stability
Biochimie
78
390-398
1996
Escherichia coli
Scorilas, A.; Talieri, M.; Ardavanis, A.; Courtis, N.; Dimitriadis, E.; Yotis, J.; Tsiapalis, C.M.; Trangas, T.
Polyadenylate polymerase enzymatic activity in mammary tumor cytosols: a new independent prognostic marker in primary breast cancer
Cancer Res.
60
5427-5433
2000
Homo sapiens
Das Gupta, J.; Li, Q.; Thomson, A.B.; Hunt, A.G.
Characterization of a novel plant poly(A) polymerase
Plant Sci.
110
215-226
1995
Brassica juncea, Pisum sativum, Zea mays
-
Gebauer, F.; Richter, J.D.
Cloning and characterization of a Xenopus poly(A) polymerase
Mol. Cell. Biol.
15
1422-1430
1995
Xenopus laevis
Kyriakopoulou, C.; Tsiapalis, C.M.; Havredaki, M.
Biochemical and immunological identification and enrichment of poly(A) polymerase from human thymus
Mol. Cell. Biochem.
154
9-16
1996
Homo sapiens
Raynal, L.C.; Carpousis, A.J.
Poly(A) polymerase I of Escherichia coli: characterization of the catalytic domain, an RNA binding site and regions for the interaction with proteins involved in mRNA degradation
Mol. Microbiol.
32
765-775
1999
Escherichia coli
Sillero, M.A.; de Diego, A.; Silles, E.; Osorio, H.; Sillero, A.
Polyphosphates strongly inhibit the tRNA dependent synthesis of poly(A) catalyzed by poly(A) polymerase from Saccharomyces cerevisiae
FEBS Lett.
550
41-45
2003
Saccharomyces cerevisiae
Sarkar, B.; Cao, G.J.; Sarkar, N.
Identification of two poly(A) polymerases in Bacillus subtilis
Biochem. Mol. Biol. Int.
41
1045-1050
1997
Bacillus subtilis
Topalian, S.L.; Kaneko, S.; Gonzales, M.I.; Bond, G.L.; Ward, Y.; Manley, J.L.
Identification and functional characterization of neo-poly(A) polymerase, an RNA processing enzyme overexpressed in human tumors
Mol. Cell. Biol.
21
5614-5623
2001
Homo sapiens (Q9BWT3), Homo sapiens
Hunt, A.G.; Meeks, L.R.; Forbes, K.P.; Das Gupta, J.; Mogen, B.D.
Nuclear and chloroplast poly(A) polymerases from plants share a novel biochemical property
Biochem. Biophys. Res. Commun.
272
174-181
2000
Arabidopsis thaliana (O82312)
Wittmann, T.; Wahle, E.
Purification and characterization of full-length mammalian poly(A) polymerase
Biochim. Biophys. Acta
1350
293-305
1997
Bos taurus
Kim, H.; Lee, Y.
Interaction of Poly(A) Polymerase with the 25-kDa Subunit of Cleavage Factor I
Biochem. Biophys. Res. Commun.
289
513-518
2001
Mus musculus
Bralley, P.; Jones, G.H.
Poly(A) polymerase activity and RNA polyadenylation in Streptomyces coelicolor A3(2)
Mol. Microbiol.
40
1155-1164
2001
Streptomyces coelicolor
Hooker, L.; Strong, R.; Adams, R.; Handa, B.; Merrett, J.H.; Martin, J.A.; Klumpp, K.
A sensitive, single-tube assay to measure the enzymatic activities of influenza RNA polymerase and other poly(A) polymerases: application to kinetic and inhibitor analysis
Nucleic Acids Res.
29
2691-2698
2001
Saccharomyces cerevisiae
Yehudai-Resheff, S.; Schuster, G.
Characterization of the E.coli poly(A) polymerase: nucleotide specificity, RNA-binding affinities and RNA structure dependence
Nucleic Acids Res.
28
1139-1144
2000
Escherichia coli
Zhelkovsky, A.M.; Kessler, M.M.; Moore, C.L.
Structure-function relationships in the Saccharomyces cerevisiae poly(A) polymerase. Identification of a novel RNA binding site and a domain that interacts with specificity factor(s)
J. Biol. Chem.
270
26715-26720
1995
Saccharomyces cerevisiae
Sillero, M.A.; De Diego, A.; Osorio, H.; Sillero, A.
Dinucleoside polyphosphates stimulate the primer independent synthesis of poly(A) catalyzed by yeast poly(A) polymerase
Eur. J. Biochem.
269
5323-5329
2002
Saccharomyces cerevisiae
Sillero, M.A.; Socorro, S.; Baptista, M.J.; Del Valle, M.; De Diego, A.; Sillero, A.
Poly(A) polymerase from Escherichia coli adenylylates the 3'-hydroxyl residue of nucleosides, nucleoside 5'-phosphates and nucleoside(5')oligophospho(5')nucleosides (NpnN)
Eur. J. Biochem.
268
3605-3611
2001
Escherichia coli
Kerwitz, Y.; Kuehn, U.; Lilie, H.; Knoth, A.; Scheuermann, T.; Friedrich, H.; Schwarz, E.; Wahle, E.
Stimulation of poly(A) polymerase through a direct interaction with the nuclear poly(A) binding protein allosterically regulated by RNA
EMBO J.
22
3705-3714
2003
Bos taurus
Betat, H.; Rammelt, C.; Martin, G.; Moerl, M.
Exchange of regions between bacterial poly(A) polymerase and the CCA-adding enzyme generates altered specificities
Mol. Cell
15
389-398
2004
Escherichia coli
Jasiecki, J.; Wegrzyn, G.
Localization of Escherichia coli poly(A) polymerase I in cellular membrane
Biochem. Biophys. Res. Commun.
329
598-602
2005
Escherichia coli
Balbo, P.B.; Meinke, G.; Bohm, A.
Kinetic studies of yeast polyA polymerase indicate an induced fit mechanism for nucleotide specificity
Biochemistry
44
7777-7786
2005
Saccharomyces cerevisiae
Addepalli, B.; Meeks, L.R.; Forbes, K.P.; Hunt, A.G.
Novel alternative splicing of mRNAs encoding poly(A) polymerases in Arabidopsis
Biochim. Biophys. Acta
1679
117-128
2004
Arabidopsis thaliana (O82312), Arabidopsis thaliana (Q7XJ91), Arabidopsis thaliana (Q7XJ92), Arabidopsis thaliana (Q9LMT2), Arabidopsis thaliana
Thomadaki, H.; Tsiapalis, C.M.; Scorilas, A.
Polyadenylate polymerase modulations in human epithelioid cervix and breast cancer cell lines, treated with etoposide or cordycepin, follow cell cycle rather than apoptosis induction
Biol. Chem.
386
471-480
2005
Homo sapiens
Folichon, M.; Allemand, F.; Regnier, P.; Hajnsdorf, E.
Stimulation of poly(A) synthesis by Escherichia coli poly(A)polymerase I is correlated with Hfq binding to poly(A) tails
FEBS J.
272
454-463
2005
Escherichia coli
Chen, L.S.; Sheppard, T.L.
Chain termination and inhibition of Saccharomyces cerevisiae poly(A) polymerase by C-8-modified ATP analogs
J. Biol. Chem.
279
40405-40411
2004
Saccharomyces cerevisiae
Nagaike, T.; Suzuki, T.; Katoh, T.; Ueda, T.
Human mitochondrial mRNAs are stabilized with polyadenylation regulated by mitochondria-specific poly(A) polymerase and polynucleotide phosphorylase
J. Biol. Chem.
280
19721-19727
2005
Homo sapiens
Martin, G.; Moglich, A.; Keller, W.; Doublie, S.
Biochemical and structural insights into substrate binding and catalytic mechanism of mammalian poly(A) polymerase
J. Mol. Biol.
341
911-925
2004
Bos taurus
Tomecki, R.; Dmochowska, A.; Gewartowski, K.; Dziembowski, A.; Stepien, P.P.
Identification of a novel human nuclear-encoded mitochondrial poly(A) polymerase
Nucleic Acids Res.
32
6001-6014
2004
Homo sapiens (Q9NVV4), Homo sapiens
Kwak, J.E.; Wang, L.; Ballantyne, S.; Kimble, J.; Wickens, M.
Mammalian GLD-2 homologs are poly(A) polymerases
Proc. Natl. Acad. Sci. USA
101
4407-4412
2004
Caenorhabditis elegans
Zhelkovsky, A.; Helmling, S.; Bohm, A.; Moore, C.
Mutations in the middle domain of yeast poly(A) polymerase affect interactions with RNA but not ATP
RNA
10
558-564
2004
Saccharomyces cerevisiae
Rouhana, L.; Wang, L.; Buter, N.; Kwak, J.E.; Schiltz, C.A.; Gonzalez, T.; Kelley, A.E.; Landry, C.F.; Wickens, M.
Vertebrate GLD2 poly(A) polymerases in the germline and the brain
RNA
11
1117-1130
2005
Homo sapiens, Mus musculus, Xenopus laevis
Nakanishi, T.; Kubota, H.; Ishibashi, N.; Kumagai, S.; Watanabe, H.; Yamashita, M.; Kashiwabara, S.; Miyado, K.; Baba, T.
Possible role of mouse poly(A) polymerase mGLD-2 during oocyte maturation
Dev. Biol.
289
115-126
2006
Mus musculus
Houseley, J.; Tollervey, D.
Yeast Trf5p is a nuclear poly(A) polymerase
EMBO Rep.
7
205-211
2006
Saccharomyces cerevisiae
Jasiecki, J.; Wegrzyn, G.
Phosphorylation of Escherichia coli poly(A) polymerase I and effects of this modification on the enzyme activity
FEMS Microbiol. Lett.
261
118-122
2006
Escherichia coli
Yoshizawa, J.M.; Li, C.; Gershon, P.D.
Saltatory forward movement of a poly(A) polymerase during poly(A) tail addition
J. Biol. Chem.
282
19144-19151
2007
Vaccinia virus
Moure, C.M.; Bowman, B.R.; Gershon, P.D.; Quiocho, F.A.
Crystal structures of the vaccinia virus polyadenylate polymerase heterodimer: insights into ATP selectivity and processivity
Mol. Cell
22
339-349
2006
Vaccinia virus
Santos, J.M.; Freire, P.; Mesquita, F.S.; Mika, F.; Hengge, R.; Arraiano, C.M.
Poly(A)-polymerase I links transcription with mRNA degradation via sigmaS proteolysis
Mol. Microbiol.
60
177-188
2006
Escherichia coli
Suh, N.; Jedamzik, B.; Eckmann, C.R.; Wickens, M.; Kimble, J.
The GLD-2 poly(A) polymerase activates gld-1 mRNA in the Caenorhabditis elegans germ line
Proc. Natl. Acad. Sci. USA
103
15108-15112
2006
Caenorhabditis elegans
Cho, H.D.; Verlinde, C.L.; Weiner, A.M.
Reengineering CCA-adding enzymes to function as (U,G)- or dCdCdA-adding enzymes or poly(C,A) and poly(U,G) polymerases
Proc. Natl. Acad. Sci. USA
104
54-59
2007
Escherichia coli
Rouhana, L.; Wickens, M.
Autoregulation of GLD-2 cytoplasmic poly(A) polymerase
RNA
13
188-199
2007
Xenopus laevis
Balbo, P.B.; Bohm, A.
Mechanism of poly(A) polymerase: Structure of the enzyme-MgATP-RNA ternary complex and kinetic analysis
Structure
15
1117-1131
2007
Saccharomyces cerevisiae (P29468), Saccharomyces cerevisiae
Bougie, I.; Bisaillon, M.
Characterization of the RNA binding energetics of the Candida albicans poly(A) polymerase
Yeast
24
431-446
2007
Candida albicans
Nakanishi, T.; Kumagai, S.; Kimura, M.; Watanabe, H.; Sakurai, T.; Kimura, M.; Kashiwabara, S.; Baba, T.
Disruption of mouse poly(A) polymerase mGLD-2 does not alter polyadenylation status in oocytes and somatic cells
Biochem. Biophys. Res. Commun.
364
14-19
2007
Mus musculus
Meinke, G.; Ezeokonkwo, C.; Balbo, P.; Stafford, W.; Moore, C.; Bohm, A.
Structure of yeast poly(A) polymerase in complex with a peptide from Fip1, an intrinsically disordered protein
Biochemistry
47
6859-6869
2008
Saccharomyces cerevisiae (P29468), Saccharomyces cerevisiae
Kashiwabara, S.; Nakanishi, T.; Kimura, M.; Baba, T.
Non-canonical poly(A) polymerase in mammalian gametogenesis
Biochim. Biophys. Acta
1779
230-238
2008
Mus musculus
Slomovic, S.; Portnoy, V.; Yehudai-Resheff, S.; Bronshtein, E.; Schuster, G.
Polynucleotide phosphorylase and the archaeal exosome as poly(A)-polymerases
Biochim. Biophys. Acta
1779
247-255
2008
Homo sapiens
Thuresson, A.; Kirsebom, L.A.; Virtanen, A.
Inhibition of poly(A) polymerase by aminoglycosides
Biochimie
89
1221-1227
2007
Homo sapiens
Benoit, P.; Papin, C.; Kwak, J.E.; Wickens, M.; Simonelig, M.
PAP- and GLD-2-type poly(A) polymerases are required sequentially in cytoplasmic polyadenylation and oogenesis in Drosophila
Development
135
1969-1979
2008
Drosophila melanogaster
Choi, H.S.; Lee, S.H.; Kim, H.; Lee, Y.
Germ cell-specific gene 1 targets testis-specific poly(A) polymerase to the endoplasmic reticulum through protein-protein interactions
FEBS Lett.
582
1203-1209
2008
Mus musculus (Q9WVP6), Mus musculus
Vethantham, V.; Rao, N.; Manley, J.L.
Sumoylation regulates multiple aspects of mammalian poly(A) polymerase function
Genes Dev.
22
499-511
2008
Mus musculus
Tanaka, S.; Takayanagi, N.; Murasawa, K.; Ishii, C.; Inoue, H.
Genetic and molecular analysis of the temperature-sensitive mutant un-17 carrying a mutation in the gene encoding poly(A)-polymerase in Neurospora crassa
Genes Genet. Syst.
82
447-454
2007
Neurospora crassa
Balbo, P.B.; Toth, J.; Bohm, A.
X-ray crystallographic and steady state fluorescence characterization of the protein dynamics of yeast polyadenylate polymerase
J. Mol. Biol.
366
1401-1415
2007
Saccharomyces cerevisiae (P29468), Saccharomyces cerevisiae
Rissland, O.S.; Mikulasova, A.; Norbury, C.J.
Efficient RNA polyuridylation by noncanonical poly(A) polymerases
Mol. Cell. Biol.
27
3612-3624
2007
Homo sapiens
Mellman, D.L.; Gonzales, M.L.; Song, C.; Barlow, C.A.; Wang, P.; Kendziorski, C.; Anderson, R.A.
A PtdIns4,5P2-regulated nuclear poly(A) polymerase controls expression of select mRNAs
Nature
451
1013-1017
2008
Saccharomyces cerevisiae
Holbein, S.; Freimoser, F.M.; Werner, T.P.; Wengi, A.; Dichtl, B.
Cordycepin-hypersensitive growth links elevated polyphosphate levels to inhibition of poly(A) polymerase in Saccharomyces cerevisiae
Nucleic Acids Res.
36
353-363
2008
Bos taurus, Saccharomyces cerevisiae, Saccharomyces cerevisiae BY4741
Just, A.; Butter, F.; Trenkmann, M.; Heitkam, T.; Moerl, M.; Betat, H.
A comparative analysis of two conserved motifs in bacterial poly(A) polymerase and CCA-adding enzyme
Nucleic Acids Res.
36
5212-5220
2008
Escherichia coli (P0ABF1), Escherichia coli
Lee, S.H.; Choi, H.S.; Kim, H.; Lee, Y.
ERK is a novel regulatory kinase for poly(A) polymerase
Nucleic Acids Res.
36
803-813
2008
Mus musculus
Kwak, J.E.; Drier, E.; Barbee, S.A.; Ramaswami, M.; Yin, J.C.; Wickens, M.
GLD2 poly(A) polymerase is required for long-term memory
Proc. Natl. Acad. Sci. USA
105
14644-14649
2008
Drosophila melanogaster
Becker, M.N.; Todd, T.M.; Moyer, R.W.
An Amsacta moorei entomopoxvirus ortholog of the poly(A) polymerase small subunit exhibits methyltransferase activity and is non-essential for virus growth
Virology
375
624-636
2008
Amsacta moorei entomopoxvirus
Chen, L.S.; Du-Cuny, L.; Vethantham, V.; Hawke, D.H.; Manley, J.L.; Zhang, S.; Gandhi, V.
Chain termination and inhibition of mammalian poly(A) polymerase by modified ATP analogues
Biochem. Pharmacol.
79
669-677
2010
Bos taurus (P25500), Bos taurus
Yang, Q.; Faucher, F.; Coseno, M.; Heckman, J.; Doublie, S.
Purification, crystallization and preliminary X-ray diffraction of a disulfide cross-linked complex between bovine poly(A) polymerase and a chemically modified 15-mer oligo(A) RNA
Acta Crystallogr. Sect. F
67
241-244
2011
Bos taurus (P25500), Bos taurus
Sartain, C.V.; Cui, J.; Meisel, R.P.; Wolfner, M.F.
The poly(A) polymerase GLD2 is required for spermatogenesis in Drosophila melanogaster
Development
138
1619-1629
2011
Drosophila melanogaster (Q9VD44), Drosophila melanogaster
Ezeokonkwo, C.; Ghazy, M.A.; Zhelkovsky, A.; Yeh, P.C.; Moore, C.
Novel interactions at the essential N-terminus of poly(A) polymerase that could regulate poly(A) addition in Saccharomyces cerevisiae
FEBS Lett.
586
1173-1178
2012
Saccharomyces cerevisiae (P29468), Saccharomyces cerevisiae
Bai, Y.; Srivastava, S.K.; Chang, J.H.; Manley, J.L.; Tong, L.
Structural basis for dimerization and activity of human PAPD1, a noncanonical poly(A) polymerase
Mol. Cell
41
311-320
2011
Homo sapiens (Q9NVV4), Homo sapiens
Maes, A.; Gracia, C.; Hajnsdorf, E.; Regnier, P.
Search for poly(A) polymerase targets in E. coli reveals its implication in surveillance of Glu tRNA processing and degradation of stable RNAs
Mol. Microbiol.
83
436-451
2012
Escherichia coli
Burns, D.M.; DAmbrogio, A.; Nottrott, S.; Richter, J.D.
CPEB and two poly(A) polymerases control miR-122 stability and p53 mRNA translation
Nature
473
105-108
2011
Homo sapiens (Q6PIY7), Homo sapiens
Kim, K.W.; Wilson, T.L.; Kimble, J.
GLD-2/RNP-8 cytoplasmic poly(A) polymerase is a broad-spectrum regulator of the oogenesis program
Proc. Natl. Acad. Sci. USA
107
17445-17450
2010
Caenorhabditis elegans (O17087), Caenorhabditis elegans
Keller, C.; Woolcock, K.; Hess, D.; Buehler, M.
Proteomic and functional analysis of the noncanonical poly(A) polymerase Cid14
RNA
16
1124-1129
2010
Schizosaccharomyces pombe (Q9UTN3), Schizosaccharomyces pombe, Schizosaccharomyces pombe ATCC 24843 (Q9UTN3)
Rammelt, C.; Bilen, B.; Zavolan, M.; Keller, W.
PAPD5, a noncanonical poly(A) polymerase with an unusual RNA-binding motif
RNA
17
1737-1746
2011
Homo sapiens (Q8NDF8), Homo sapiens
Ogami, K.; Cho, R.; Hoshino, S.
Molecular cloning and characterization of a novel isoform of the non-canonical poly(A) polymerase PAPD7
Biochem. Biophys. Res. Commun.
432
135-140
2013
Homo sapiens (Q5XG87)
Yang, Q.; Nausch, L.W.; Martin, G.; Keller, W.; Doublie, S.
Crystal structure of human poly(A) polymerase gamma reveals a conserved catalytic core for canonical poly(A) polymerases
J. Mol. Biol.
426
43-50
2014
Homo sapiens (Q9BWT3), Homo sapiens
Muniz, L.; Davidson, L.; West, S.
Poly(A) polymerase and the nuclear poly(A) binding protein, PABPN1, coordinate the splicing and degradation of a subset of human pre-mRNAs
Mol. Cell. Biol.
35
2218-2230
2015
Homo sapiens
Mohanty, B.; Kushner, S.
Deregulation of poly(A) polymerase I in Escherichia coli inhibits protein synthesis and leads to cell death
Nucleic Acids Res.
41
1757-1766
2013
Escherichia coli (P0ABF1)
Losh, J.S.; King, A.K.; Bakelar, J.; Taylor, L.; Loomis, J.; Rosenzweig, J.A.; Johnson, S.J.; van Hoof, A.
Interaction between the RNA-dependent ATPase and poly(A) polymerase subunits of the TRAMP complex is mediated by short peptides and important for snoRNA processing
Nucleic Acids Res.
43
1848-1858
2015
Saccharomyces cerevisiae (P48561)
Lapkouski, M.; Haellberg, B.M.
Structure of mitochondrial poly(A) RNA polymerase reveals the structural basis for dimerization, ATP selectivity and the SPAX4 disease phenotype
Nucleic Acids Res.
43
9065-9075
2015
Gallus gallus (F1NBW0)
Fiedler, M.; Rossmanith, W.; Wahle, E.; Rammelt, C.
Mitochondrial poly(A) polymerase is involved in tRNA repair
Nucleic Acids Res.
43
9937-9949
2015
Homo sapiens (Q9NVV4)
Trost, G.; Vi, S.L.; Czesnick, H.; Lange, P.; Holton, N.; Giavalisco, P.; Zipfel, C.; Kappel, C.; Lenhard, M.
Arabidopsis poly(A) polymerase PAPS1 limits founder-cell recruitment to organ primordia and suppresses the salicylic acid-independent immune response downstream of EDS1/PAD4
Plant J.
77
688-699
2014
Arabidopsis thaliana (Q9LMT2), Arabidopsis thaliana
Bresson, S.M.; Conrad, N.K.
The human nuclear poly(a)-binding protein promotes RNA hyperadenylation and decay
PLoS Genet.
9
e1003893
2013
Homo sapiens (P51003), Homo sapiens (Q9BWT3)
Vi, S.L.; Trost, G.; Lange, P.; Czesnick, H.; Rao, N.; Lieber, D.; Laux, T.; Gray, W.M.; Manley, J.L.; Groth, D.; Kappel, C.; Lenhard, M.
Target specificity among canonical nuclear poly(A) polymerases in plants modulates organ growth and pathogen response
Proc. Natl. Acad. Sci. USA
110
13994-13999
2013
Arabidopsis thaliana (Q8VYW1), Arabidopsis thaliana (Q9LMT2)
Nakel, K.; Bonneau, F.; Eckmann, C.R.; Conti, E.
Structural basis for the activation of the C. elegans noncanonical cytoplasmic poly(A)-polymerase GLD-2 by GLD-3
Proc. Natl. Acad. Sci. USA
112
8614-8619
2015
Caenorhabditis elegans (O17087), Caenorhabditis elegans
Koch, H.; Raabe, M.; Urlaub, H.; Bindereif, A.; Preusser, C.
The polyadenylation complex of Trypanosoma brucei: Characterization of the functional poly(A) polymerase
RNA Biol.
13
221-231
2016
Trypanosoma brucei brucei (Q57WJ3), Trypanosoma brucei brucei (Q57ZJ6), Trypanosoma brucei brucei 927 / 4 GUTat10.1 / TREU927 (Q57WJ3), Trypanosoma brucei brucei 927 / 4 GUTat10.1 / TREU927 (Q57ZJ6)
Nakel, K.; Bonneau, F.; Basquin, C.; Habermann, B.; Eckmann, C.R.; Conti, E.
Structural basis for the antagonistic roles of RNP-8 and GLD-3 in GLD-2 poly(A)-polymerase activity
RNA
22
1139-1145
2016
Caenorhabditis elegans (O17087), Caenorhabditis elegans
Yamashita, S.; Takeshita, D.; Tomita, K.
Translocation and rotation of tRNA during template-independent RNA polymerization by tRNA nucleotidyltransferase
Structure
22
315-325
2014
Aquifex aeolicus (O67911), Aquifex aeolicus
Yu, C.; Gong, Y.; Zhou, H.; Wang, M.; Kong, L.; Liu, J.; An, T.; Zhu, H.; Li, Y.
Star-PAP, a poly(A) polymerase, functions as a tumor suppressor in an orthotopic human breast cancer model
Cell Death Dis.
8
e2582
2017
Homo sapiens (Q9H6E5), Homo sapiens
Furuya, N.; Kakuta, S.; Sumiyoshi, K.; Ando, M.; Nonaka, R.; Suzuki, A.; Kazuno, S.; Saiki, S.; Hattori, N.
NDP52 interacts with mitochondrial RNA poly(A) polymerase to promote mitophagy
EMBO Rep.
19
e46363
2018
Homo sapiens (Q9NVV4)
Kashiwabara, S.I.; Tsuruta, S.; Okada, K.; Yamaoka, Y.; Baba, T.
Adenylation by testis-specific cytoplasmic poly(A) polymerase, PAPOLB/TPAP, is essential for spermatogenesis
J. Reprod. Dev.
62
607-614
2016
Mus musculus (Q9WVP6)
Kashiwabara, S.I.; Tsuruta, S.; Yamaoka, Y.; Oyama, K.; Iwazaki, C.; Baba, T.
PAPOLB/TPAP regulates spermiogenesis independently of chromatoid body-associated factors
J. Reprod. Dev.
64
25-31
2018
Mus musculus (Q9WVP6)
Mroczek, S.; Chlebowska, J.; Kulinski, T.M.; Gewartowska, O.; Gruchota, J.; Cysewski, D.; Liudkovska, V.; Borsuk, E.; Nowis, D.; Dziembowski, A.
The non-canonical poly(A) polymerase FAM46C acts as an onco-suppressor in multiple myeloma
Nat. Commun.
8
619
2017
Mus musculus (Q5SSF7), Mus musculus, Homo sapiens (Q5VWP2)
Kuchta, K.; Muszewska, A.; Knizewski, L.; Steczkiewicz, K.; Wyrwicz, L.S.; Pawlowski, K.; Rychlewski, L.; Ginalski, K.
FAM46 proteins are novel eukaryotic non-canonical poly(A) polymerases
Nucleic Acids Res.
44
3534-3548
2016
Homo sapiens (Q5VWP2), Homo sapiens (Q8NEK8), Homo sapiens (Q96A09), Homo sapiens (Q96IP4), Homo sapiens
Shin, J.; Paek, K.; Ivshina, M.; Stackpole, E.; Richter, J.
Essential role for non-canonical poly(A) polymerase GLD4 in cytoplasmic polyadenylation and carbohydrate metabolism
Nucleic Acids Res.
45
6793-6804
2017
Homo sapiens (Q8NDF8)
Li, W.; Li, W.; Laishram, R.S.; Hoque, M.; Ji, Z.; Tian, B.; Anderson, R.A.
Distinct regulation of alternative polyadenylation and gene expression by nuclear poly(A) polymerases
Nucleic Acids Res.
45
8930-8942
2017
Homo sapiens
Hu, J.L.; Liang, H.; Zhang, H.; Yang, M.Z.; Sun, W.; Zhang, P.; Luo, L.; Feng, J.X.; Bai, H.; Liu, F.; Zhang, T.; Yang, J.Y.; Gao, Q.; Long, Y.; Ma, X.Y.; Chen, Y.; Zhong, Q.; Yu, B.; Liao, S.; Wang, Y.; Zhao, Y.; Zeng, M.S.; Cao, N.; Wang, J.; Chen, W.; Yang, H.T.; Gao, S.
FAM46B is a prokaryotic-like cytoplasmic poly(A) polymerase essential in human embryonic stem cells
Nucleic Acids Res.
48
2733-2748
2020
Xenopus tropicalis (F7E7M3), Homo sapiens (Q96A09), Homo sapiens
Czesnick, H.; Lenhard, M.
Antagonistic control of flowering time by functionally specialized poly(A) polymerases in Arabidopsis thaliana
Plant J.
88
570-583
2016
Arabidopsis thaliana (O82312), Arabidopsis thaliana (Q8YYW1), Arabidopsis thaliana (Q9LMT2), Arabidopsis thaliana
Zhang, Y.; Ramming, A.; Heinke, L.; Altschmied, L.; Slotkin, R.K.; Becker, J.D.; Kappel, C.; Lenhard, M.
The poly(A) polymerase PAPS1 interacts with the RNA-directed DNA-methylation pathway in sporophyte and pollen development
Plant J.
99
655-672
2019
Arabidopsis thaliana (Q9LMT2), Arabidopsis thaliana
Mansur, F.; Alarcon, J.; Stackpole, E.; Wang, R.; Richter, J.
Noncanonical cytoplasmic poly(A) polymerases regulate RNA levels, alternative RNA processing, and synaptic plasticity but not hippocampal-dependent behaviours
RNA Biol.
18
962-971
2020
Mus musculus (Q68ED3), Mus musculus (Q91YI6), Mus musculus
Newie, I.; Sokilde, R.; Persson, H.; Jacomasso, T.; Gorbatenko, A.; Borg, A.; de Hoon, M.; Pedersen, S.F.; Rovira, C.
HER2-encoded mir-4728 forms a receptor-independent circuit with miR-21-5p through the non-canonical poly(A) polymerase PAPD5
Sci. Rep.
6
35664
2016
Homo sapiens (Q8NDF8), Homo sapiens
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