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Literature summary for 2.7.7.19 extracted from

  • Topalian, S.L.; Kaneko, S.; Gonzales, M.I.; Bond, G.L.; Ward, Y.; Manley, J.L.
    Identification and functional characterization of neo-poly(A) polymerase, an RNA processing enzyme overexpressed in human tumors (2001), Mol. Cell. Biol., 21, 5614-5623.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine enzyme is overexpressed in cancers Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
-
Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus
-
Homo sapiens 5634
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
82800
-
x * 83000, SDS-PAGE, x * 82800, deduced from gene sequence Homo sapiens
83000
-
x * 83000, SDS-PAGE, x * 82800, deduced from gene sequence Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9BWT3
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
additional information no phosphoprotein Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
melanoma cell line
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + RNA highly specific for ATP Homo sapiens diphosphate + RNA(A)n
-
r

Subunits

Subunits Comment Organism
? x * 83000, SDS-PAGE, x * 82800, deduced from gene sequence Homo sapiens