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2.3.1.87: aralkylamine N-acetyltransferase

This is an abbreviated version!
For detailed information about aralkylamine N-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.87

Reaction

acetyl-CoA
+
a 2-arylethylamine
=
CoA
 +
an N-acetyl-2-arylethylamine

Synonyms

AA-NAT, AANAT, AANAT1, AANAT2, AANAT3, AANATL7, AATNATL2, acetyl-CoA:aralkylamine N-acetyltransferase, acetyltransferase, arylalkylamine N-, arylalkylamine N-acetyltransferase, arylalkylamine N-acetyltransferase 1, arylalkylamine N-acetyltransferase 1a, arylalkylamine N-acetyltransferase 1b, arylalkylamine N-acetyltransferase 2, arylalkylamine N-acetyltransferase like 7, arylalkylamine N-acetyltransferase-2, Bm-iAANAT, Eis, hAANAT, More, MSMEG_3513, N-acetyltransferase, NAT, oAANAT, PA4534, PaaNAT, Rv2416c, serotonin acetylase, serotonin acetyltransferase, serotonin N-acetyltransferase, serotonin-N-acetyltransferase, SNA, SNAT, SNAT1, SNAT2

ECTree

     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.87 aralkylamine N-acetyltransferase

Reference

topprint

Reference on EC 2.3.1.87 - aralkylamine N-acetyltransferase

Please use the Reference Search for a specific query.
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Fajardo, N.; Abreu, P.; Alonso, R.
Determination of kinetic properties of serotonin-N-acetyltransferase in bovine pineal gland using HPLC with fluorimetric detection
J. Pineal Res.
13
80-84
1992
Bos taurus, Rattus norvegicus
Manually annotated by BRENDA team
Morrissey, J.J.; Edwards, S.B.; Lovenberg, W.
Comparison of rat pineal gland and rat liver serotonin-N-acetyltransferase
Biochem. Biophys. Res. Commun.
77
118-123
1977
Rattus norvegicus
Manually annotated by BRENDA team
Ohtomi, M.; Sasaki, M.; Deguchi, T.
Two arylamine N-acetyltransferases from chicken pineal gland as identified by cDNA cloning
Eur. J. Biochem.
185
253-261
1989
Gallus gallus
Manually annotated by BRENDA team
Namboodiri, M.A.A.; Dubbels, R.; Klein, D.C.
Arylalkylamine N-acetyltransferase from mammalian pineal gland
Methods Enzymol.
142
583-590
1987
Ovis aries, Rattus norvegicus
Manually annotated by BRENDA team
Voisin, P.; Namboodiri, M.A.A.; Klein, D.C.
Arylamine N-acetyltransferase and arylalkylamine N-acetyltransferase in the mammalian pineal gland
J. Biol. Chem.
259
10913-10918
1984
Ovis aries, Rattus norvegicus
Manually annotated by BRENDA team
Withyachumnarnkul, B.; Pongsa-Asawapaiboon, A.; Poolsanguan, B.
Characteristics of the enzyme N-acetyltransferase in the optic lobe of the giant freshwater prawn, Macrobrrachium rosenbergii
Comp. Biochem. Physiol. B
104
449-454
1993
Macrobrachium rosenbergii
-
Manually annotated by BRENDA team
Namboodiri, M.A.A.; Brownstein, M.J.; Voisin, P.; Weller, J.L.; Klein, D.C.
A simple and rapid method for the purification of ovine pineal arylalkylamine N-acetyltransferase
J. Neurochem.
48
580-585
1987
Ovis aries, Rattus norvegicus
Manually annotated by BRENDA team
Rodriguez-Cabello, J.C.; Agapito, M.T.; Garcia-Herrero, I.; Recio, J.M.
Effects of EGTA and calmodulin, neutral thiol proteinases and protein kinase C inhibitors on loss of chicken pineal serotonin N-acetyltransferase activity
J. Comp. Physiol. B
159
583-588
1989
Gallus gallus
Manually annotated by BRENDA team
Namboodiri, M.A.A.; Brownstein, M.J.; Weller, J.L.; Voisin, P.; Klein, D.C.
Multiple forms of arylalkylamine N-acetyltransferases in the rat pineal gland: purification of one molecular form
J. Pineal Res.
4
235-246
1987
Rattus norvegicus
Manually annotated by BRENDA team
Deguchi, T.
Characteristics of serotonin-acetyl coenzyme A N-acetyltransferase in pineal gland of rat
J. Neurochem.
24
1083-1085
1975
Rattus norvegicus
Manually annotated by BRENDA team
Fleming, J.V.; Barrett, P.; Coon, S.L.; Klein, D.C.; Morgan, P.J.
Ovine arylalkylamine N-acetyltransferase in the pineal and pituitary glands: differences in function and regulation
Endocrinology
140
972-978
1999
Ovis aries
Manually annotated by BRENDA team
Falcon, J.; Galarneau, K.M.; Weller, J.L.; Ron, B.; Chen, G.; Coon, S.L.; Klein, D.C.
Regulation of arylalkylamine N-acetyltransferase-2 (AANAT2, EC 2.3.1.87) in the fish pineal organ: evidence for a role of proteasomal proteolysis
Endocrinology
142
1804-1813
2001
Esox sp., Sparus aurata, trout
Manually annotated by BRENDA team
Coon, S.L.; Del Olmo, E.; Young, W.S.; Klein, D.C.
Melatonin synthesis enzymes in Macaca mulatta: focus on arylalkylamine N-acetyltransferase (EC 2.3.1.87)
J. Clin. Endocrinol. Metab.
87
4699-4706
2002
Macaca mulatta (O97756), Macaca mulatta
Manually annotated by BRENDA team
Aisien, S.O.; Hellmund, C.; Walter, R.D.
Characterization of the arylalkylamine N-acetyltransferase in Onchocerca volvulus
Parasitol. Res.
82
369-371
1996
Onchocerca volvulus
Manually annotated by BRENDA team
Obsil, T.; Ghirlando, R.; Klein, D.C.; Ganguly, S.; Dyda, F.
Crystal structure of the 14-3-3zeta:serotonin N-acetyltransferase complex: a role for scaffolding in enzyme regulation
Cell
105
257-267
2001
Ovis aries
Manually annotated by BRENDA team
Hamada, T.; Ootomi, M.; Horikawa, K.; Niki, T.; Wakamatu, H.; Ishida, N.
The expression of the melatonin synthesis enzyme: arylalkylamine N-acetyltransferase in the suprachiasmatic nucleus of rat brain
Biochem. Biophys. Res. Commun.
258
772-777
1999
Rattus norvegicus
Manually annotated by BRENDA team
Amherd, R.; Hintermann, E.; Walz, D.; Affolter, M.; Meyer, U.A.
Purification, cloning, and characterization of a second arylalkylamine N-acetyltransferase from Drosophila melanogaster
DNA Cell Biol.
19
697-705
2000
Drosophila melanogaster, Drosophila melanogaster AANAT2
Manually annotated by BRENDA team
Alonso-Gomez, A.L.; Valenciano, A.I.; Alonso-Bedate, M.; Delgado, M.J.
Differential characteristics and regulation of arylamine and arylalkylamine N-acetyltransferases in the frog retina (Rana perezi)
Neurochem. Int.
26
223-231
1995
Pelophylax perezi
Manually annotated by BRENDA team
Ivanova, T.N.; Michael Iuvone, P.
Melatonin synthesis in retina: circadian regulation of arylalkylamine N-acetyltransferase activity in cultured photoreceptor cells of embryonic chicken retina
Brain Res.
973
56-63
2003
Gallus gallus
Manually annotated by BRENDA team
De Angelis, J.; Gastel, J.; Klein, D.C.; Cole, P.A.
Kinetic analysis of the catalytic mechanism of serotonin N-acetyltransferase (EC 2.3.1.87)
J. Biol. Chem.
273
3045-3050
1998
Ovis aries
Manually annotated by BRENDA team
Tsuboi, S.; Kotani, Y.; Ogawa, K.i.; Hatanaka, T.; Yatsushiro, S.; Otsuka, M.; Moriyama, Y.
An Intramolecular Disulfide Bridge as a Catalytic Switch for Serotonin N-Acetyltransferase
J. Biol. Chem.
277
44229-44235
2002
Rattus norvegicus (Q64666)
Manually annotated by BRENDA team
Scheibner, K.A.; De Angelis, J.; Burley, S.K.; Cole, P.A.
Investigation of the roles of catalytic residues in serotonin N-acetyltransferase
J. Biol. Chem.
277
18118-18126
2002
Ovis aries (Q29495)
Manually annotated by BRENDA team
Khalil, E.M.; De Angelis, J.; Cole, P.A.
Indoleamine analogs as probes of the substrate selectivity and catalytic mechanism of serotonin N-acetyltransferase
J. Biol. Chem.
273
30321-30327
1998
Ovis aries
Manually annotated by BRENDA team
Ferry, G.; Loynel, A.; Kucharczyk, N.; Bertin, S.; Rodriguez, M.; Delagrange, P.; Galizzi, J.P.; Jacoby, E.; Volland, J.P.; Lesieur, D.; Renard, P.; Canet, E.; Fauchere, J.L.; Boutin, J.A.
Substrate specificity and inhibition studies of human serotonin N-acetyltransferase
J. Biol. Chem.
275
8794-8805
2000
Ovis aries, Homo sapiens
Manually annotated by BRENDA team
Ichihara, N.; Okada, M.; Takeda, M.
Characterization and purification of polymorphic arylalkylamine N-acetyltransferase from the American cockroach, Periplaneta americana
Insect Biochem. Mol. Biol.
32
15-22
2001
Periplaneta americana
Manually annotated by BRENDA team
Ichihara, N.; Okada, M.; Nakagawa, H.; Takeda, M.
Purification and characterization of arylalkylamine N-acetyltransferase from cockroach testicular organs
Insect Biochem. Mol. Biol.
27
241-246
1997
Periplaneta americana
Manually annotated by BRENDA team
Asano, H.; Bembenek, J.; Takeda, M.
Multiple forms of arylalkylamine N-acetyltransferase (NAT) from cockroach female colleterial glands and activity changes during oocyte maturation
Comp. Biochem. Physiol. A
134A
795-803
2003
Periplaneta americana
-
Manually annotated by BRENDA team
Bembenek, J.; Sehadova, H.; Ichihara, N.; Takeda, M.
Day/night fluctuations in melatonin content, arylalkylamine N-acetyltransferase activity and NAT mRNA expression in the CNS, peripheral tissues and hemolymph of the cockroach, Periplaneta americana
Comp. Biochem. Physiol. B
140
27-36
2005
Periplaneta americana
Manually annotated by BRENDA team
Ferry, G.; Ubeaud, C.; Mozo, J.; Pean, C.; Hennig, P.; Rodriguez, M.; Scoul, C.; Bonnaud, A.; Nosjean, O.; Galizzi, J.P.; Delagrange, P.; Renard, P.; Volland, J.P.; Yous, S.; Lesieur, D.; Boutin, J.A.
New substrate analogues of human serotonin N-acetyltransferase produce in situ specific and potent inhibitors
Eur. J. Biochem.
271
418-428
2004
Homo sapiens
Manually annotated by BRENDA team
Zilberman-Peled, B.; Benhar, I.; Coon, S.L.; Ron, B.; Gothilf, Y.
Duality of serotonin-N-acetyltransferase in the gilthead seabream (Sparus aurata): molecular cloning and characterization of recombinant enzymes
Gen. Comp. Endocrinol.
138
139-147
2004
Sparus aurata (Q68SL6), Sparus aurata (Q68SL7), Sparus aurata
Manually annotated by BRENDA team
Choi, B.H.; Chae, H.D.; Park, T.J.; Oh, J.; Lim, J.; Kang, S.S.; Ha, H.; Kim, K.T.
Protein kinase C regulates the activity and stability of serotonin N-acetyltransferase
J. Neurochem.
90
442-454
2004
Rattus norvegicus
Manually annotated by BRENDA team
Schomerus, C.; Laedtke, E.; Korf, H.W.
Activation of arylalkylamine N-acetyltransferase by phorbol esters in bovine pinealocytes suggests a novel regulatory pathway in melatonin synthesis
J. Neuroendocrinol.
16
741-749
2004
Bos taurus
Manually annotated by BRENDA team
Ganguly, S.; Weller, J.L.; Ho, A.; Chemineau, P.; Malpaux, B.; Klein, D.C.
Melatonin synthesis: 14-3-3-dependent activation and inhibition of arylalkylamine N-acetyltransferase mediated by phosphoserine-205
Proc. Natl. Acad. Sci. USA
102
1222-1227
2005
Ovis aries
Manually annotated by BRENDA team
Ferry, G.; Ubeaud, C.; Dauly, C.; Mozo, J.; Guillard, S.; Berger, S.; Jimenez, S.; Scoul, C.; Leclerc, G.; Yous, S.; Delagrange, P.; Boutin, J.A.
Purification of the recombinant human serotonin N-acetyltransferase (EC 2.3.1.87): further characterization of and comparison with AANAT from other species
Protein Expr. Purif.
38
84-98
2004
Ovis aries, Homo sapiens (Q16613), Homo sapiens, Rattus norvegicus (Q64666)
Manually annotated by BRENDA team
Bembenek, J.; Sakamoto, K.; Takeda, M.
Molecular cloning of a cDNA encoding arylalkylamine N-acetyltransferase from the testicular system of Periplaneta americana: primary protein structure and expression analysis
Arch. Insect Biochem. Physiol.
59
219-229
2005
Periplaneta americana (Q76EI8), Periplaneta americana
Manually annotated by BRENDA team
Zilberman-Peled, B.; Ron, B.; Gross, A.; Finberg, J.P.; Gothilf, Y.
A possible new role for fish retinal serotonin-N-acetyltransferase-1 (AANAT1): Dopamine metabolism
Brain Res.
1073-1074
220-228
2006
Sparus aurata (Q68SL7), Danio rerio (Q6V7J8), Danio rerio
Manually annotated by BRENDA team
Tosini, G.; Chaurasia, S.S.; Michael Iuvone, P.
Regulation of arylalkylamine N-acetyltransferase (AANAT) in the retina
Chronobiol. Int.
23
381-391
2006
Macaca mulatta (O97756), Gallus gallus (P79774), Rattus norvegicus (Q64666), Rattus norvegicus Fischer (Q64666)
Manually annotated by BRENDA team
Tsugehara, T.; Iwai, S.; Fujiwara, Y.; Mita, K.; Takeda, M.
Cloning and characterization of insect arylalkylamine N-acetyltransferase from Bombyx mori
Comp. Biochem. Physiol. B Biochem. Mol. Biol.
147
358-366
2007
Bombyx mori (A0EM56), Bombyx mori
Manually annotated by BRENDA team
Ho, A.K.; Terriff, D.L.; Price, D.M.; Wloka, M.T.; Chik, C.L.
The role of inducible repressor proteins in the adrenergic induction of arylalkylamine-N-acetyltransferase and mitogen-activated protein kinase phosphatase-1 in rat pinealocytes
Endocrinology
148
743-751
2007
Rattus norvegicus (Q64666)
Manually annotated by BRENDA team
Fernandez-Duran, B.; Ruibal, C.; Polakof, S.; Ceinos, R.M.; Soengas, J.L.; Miguez, J.M.
Evidence for arylalkylamine N-acetyltransferase (AANAT2) expression in rainbow trout peripheral tissues with emphasis in the gastrointestinal tract
Gen. Comp. Endocrinol.
152
289-294
2006
Oncorhynchus mykiss (Q9PT39), Oncorhynchus mykiss
Manually annotated by BRENDA team
Zheng, W.; Schwarzer, D.; Lebeau, A.; Weller, J.L.; Klein, D.C.; Cole, P.A.
Cellular stability of serotonin N-acetyltransferase conferred by phosphonodifluoromethylene alanine (Pfa) substitution for Ser-205
J. Biol. Chem.
280
10462-10467
2005
Ovis aries (Q29495)
Manually annotated by BRENDA team
Han, S.; Kim, T.D.; Ha, D.C.; Kim, K.T.
Rhythmic expression of adenylyl cyclase VI contributes to the differential regulation of serotonin N-acetyltransferase by bradykinin in rat pineal glands
J. Biol. Chem.
280
38228-38234
2005
Rattus norvegicus (Q64666)
Manually annotated by BRENDA team
Koch, M.; Dehghani, F.; Habazettl, I.; Schomerus, C.; Korf, H.W.
Cannabinoids attenuate norepinephrine-induced melatonin biosynthesis in the rat pineal gland by reducing arylalkylamine N-acetyltransferase activity without involvement of cannabinoid receptors
J. Neurochem.
98
267-278
2006
Rattus norvegicus (Q64666)
Manually annotated by BRENDA team
Pozdeyev, N.; Taylor, C.; Haque, R.; Chaurasia, S.S.; Visser, A.; Thazyeen, A.; Du, Y.; Fu, H.; Weller, J.; Klein, D.C.; Iuvone, P.M.
Photic regulation of arylalkylamine N-acetyltransferase binding to 14-3-3 proteins in retinal photoreceptor cells
J. Neurosci.
26
9153-9161
2006
Gallus gallus
Manually annotated by BRENDA team
Huang, Z.; Deng, J.; Borjigin, J.
A novel H28Y mutation in LEC rats leads to decreased NAT protein stability in vivo and in vitro
J. Pineal Res.
39
84-90
2005
Rattus norvegicus (Q64666)
Manually annotated by BRENDA team
Coon, S.L.; Klein, D.C.
Evolution of arylalkylamine N-acetyltransferase: emergence and divergence
Mol. Cell. Endocrinol.
252
2-10
2006
Pelophylax perezi
Manually annotated by BRENDA team
Rosiak, J.; Zawilska, J.B.
Near-ultraviolet light perceived by the retina generates the signal suppressing melatonin synthesis in the chick pineal gland-an involvement of NMDA glutamate receptors
Neurosci. Lett.
379
214-217
2005
Gallus gallus (P79774), Gallus gallus
Manually annotated by BRENDA team
Iuvone, P.M.; Tosini, G.; Pozdeyev, N.; Haque, R.; Klein, D.C.; Chaurasia, S.S.
Circadian clocks, clock networks, arylalkylamine N-acetyltransferase, and melatonin in the retina
Prog. Retin. Eye Res.
24
433-456
2005
Gallus gallus, Rattus norvegicus, Xenopus laevis
Manually annotated by BRENDA team
Tsugehara, T.; Iwai, S.; Fujiwara, Y.; Mita, K.; Takeda, M.
Cloning and characterization of insect arylalkylamine N-acetyltransferase from Bombyx mori
Comp. Biochem. Physiol. B
147B
358-366
2007
Bombyx mori
Manually annotated by BRENDA team
Falcon, J.; Besseau, L.; Fuentes, M.; Sauzet, S.; Magnanou, E.; Boeuf, G.
Structural and functional evolution of the pineal melatonin system in vertebrates
Ann. N. Y. Acad. Sci.
1163
101-111
2009
vertebrata
Manually annotated by BRENDA team
Szewczuk, L.M.; Tarrant, M.K.; Sample, V.; Drury, W.J.; Zhang, J.; Cole, P.A.
Analysis of serotonin N-acetyltransferase regulation in vitro and in live cells using protein semisynthesis
Biochemistry
47
10407-10419
2008
Homo sapiens
Manually annotated by BRENDA team
Ceinos, R.M.; Polakof, S.; Illamola, A.R.; Soengas, J.L.; Miguez, J.M.
Food deprivation and refeeding effects on pineal indoles metabolism and melatonin synthesis in the rainbow trout Oncorhynchus mykiss
Gen. Comp. Endocrinol.
156
410-417
2008
Oncorhynchus mykiss
Manually annotated by BRENDA team
Isorna, E.; El Mrabet, A.; Confente, F.; Falcon, J.; Munoz-Cueto, J.A.
Cloning and expression of arylalkylamine N-acetyltranferase-2 during early development and metamorphosis in the sole Solea senegalensis
Gen. Comp. Endocrinol.
161
97-102
2009
Solea senegalensis
Manually annotated by BRENDA team
Pavlicek, J.; Coon, S.L.; Ganguly, S.; Weller, J.L.; Hassan, S.A.; Sackett, D.L.; Klein, D.C.
Evidence that proline focuses movement of the floppy loop of arylalkylamine N-acetyltransferase (EC 2.3.1.87)
J. Biol. Chem.
283
14552-14558
2008
Ovis aries (Q29495)
Manually annotated by BRENDA team
Suzuki, T.; Takashima, T.; Izawa, N.; Watanabe, M.; Takeda, M.
UV radiation elevates arylalkylamine N-acetyltransferase activity and melatonin content in the two-spotted spider mite, Tetranychus urticae
J. Insect Physiol.
54
1168-1174
2008
Tetranychus urticae
Manually annotated by BRENDA team
Okazaki, M.; Higuchi, K.; Hanawa, Y.; Shiraiwa, Y.; Ezura, H.
Cloning and characterization of a Chlamydomonas reinhardtii cDNA arylalkylamine N-acetyltransferase and its use in the genetic engineering of melatonin content in the Micro-Tom tomato
J. Pineal Res.
46
373-382
2009
Chlamydomonas reinhardtii
Manually annotated by BRENDA team
Bloemeke, B.; Golka, K.; Griefahn, B.; Roemer, H.C.
Arylalkylamine N-acetyltransferase (AANAT) genotype as a personal trait in melatonin synthesis
J. Toxicol. Environ. Health
71
874-876
2008
Homo sapiens
Manually annotated by BRENDA team
Gupta, B.B.; Yanthan, L.; Singh, K.M.
In vitro effects of 5-hydroxytryptophan, indoleamines and leptin on arylalkylamine N-acetyltransferase (AA-NAT) activity in pineal organ of the fish, Clarias gariepinus (Burchell, 1822) during different phases of the breeding cycle
Indian J. Exp. Biol.
48
786-792
2010
Clarias gariepinus
Manually annotated by BRENDA team
Mehere, P.; Han, Q.; Christensen, B.M.; Li, J.
Identification and characterization of two arylalkylamine N-acetyltransferases in the yellow fever mosquito, Aedes aegypti
Insect Biochem. Mol. Biol.
41
707-714
2011
Aedes aegypti
Manually annotated by BRENDA team
Dai, F.Y.; Qiao, L.; Tong, X.L.; Cao, C.; Chen, P.; Chen, J.; Lu, C.; Xiang, Z.H.
Mutations of an arylalkylamine-N-acetyltransferase, Bm-iAANAT, are responsible for silkworm melanism mutant
J. Biol. Chem.
285
19553-19560
2010
Bombyx mori (A0EM56), Bombyx mori (D6MKR1), Bombyx mori (D6MKR2), Bombyx mori
Manually annotated by BRENDA team
Kang, K.; Lee, K.; Park, S.; Kim, Y.S.; Back, K.
Enhanced production of melatonin by ectopic overexpression of human serotonin N-acetyltransferase plays a role in cold resistance in transgenic rice seedlings
J. Pineal Res.
49
176-182
2010
Homo sapiens
Manually annotated by BRENDA team
Migliori, M.L.; Romanowski, A.; Simonetta, S.H.; Valdez, D.; Guido, M.; Golombek, D.A.
Daily variation in melatonin synthesis and arylalkylamine N-acetyltransferase activity in the nematode Caenorhabditis elegans
J. Pineal Res.
53
38-46
2012
Caenorhabditis elegans (G5EDH7), Caenorhabditis elegans, Caenorhabditis elegans TJ1060 (G5EDH7)
Manually annotated by BRENDA team
Cazamea-Catalan, D.; Magnanou, E.; Helland, R.; Vanegas, G.; Besseau, L.; Boeuf, G.; Paulin, C.H.; Joergensen, E.H.; Falcon, J.
Functional diversity of Teleost arylalkylamine N-acetyltransferase-2: is the timezyme evolution driven by habitat temperature?
Mol. Ecol.
21
5027-5041
2012
Danio rerio, Esox lucius, Oncorhynchus mykiss, Thunnus thynnus, Salvelinus alpinus, Arctogadus glacialis, Oxydoras sifontesi
Manually annotated by BRENDA team
Han, Q.; Robinson, H.; Ding, H.; Christensen, B.M.; Li, J.
Evolution of insect arylalkylamine N-acetyltransferases: structural evidence from the yellow fever mosquito, Aedes aegypti
Proc. Natl. Acad. Sci. USA
109
11669-11674
2012
Aedes aegypti (Q16KL9), Aedes aegypti
Manually annotated by BRENDA team
Long, Y.; Li, J.; Zhao, T.; Li, G.; Zhu, Y.
A new arylalkylamine N-acetyltransferase in silkworm (Bombyx mori) affects integument pigmentation
Appl. Biochem. Biotechnol.
175
3447-3457
2015
Bombyx mori (A0A0F6PL61), Bombyx mori
Manually annotated by BRENDA team
Dempsey, D.R.; Jeffries, K.A.; Bond, J.D.; Carpenter, A.M.; Rodriguez-Ospina, S.; Breydo, L.; Caswell, K.K.; Merkler, D.J.
Mechanistic and structural analysis of Drosophila melanogaster arylalkylamine N-acetyltransferases
Biochemistry
53
7777-7793
2014
Drosophila melanogaster
Manually annotated by BRENDA team
Prashant, K.; Kumar, H.; Prasad, C.V.
In-silico study of arylalkylamine-nacetyltransferase enzyme to regulate circadian rhythmicity
Bioinformation
9
771-776
2013
Homo sapiens (Q16613), Homo sapiens
Manually annotated by BRENDA team
Leng, P.Q.; Zhao, F.L.; Yin, B.C.; Ye, B.C.
A novel, colorimetric method for biogenic amine detection based on arylalkylamine N-acetyltransferase
Chem. Commun. (Camb. )
51
8712-8714
2015
Aedes aegypti
Manually annotated by BRENDA team
Tsugehara, T.; Imai, T.; Takeda, M.
Characterization of arylalkylamine N-acetyltransferase from silkmoth (Antheraea pernyi) and pesticidal drug design based on the baculovirus-expressed enzyme
Comp. Biochem. Physiol. C
157
93-102
2013
Antheraea pernyi (A2SZ52), Antheraea pernyi
Manually annotated by BRENDA team
Dempsey, D.R.; Jeffries, K.A.; Anderson, R.L.; Carpenter, A.M.; Rodriquez Opsina, S.; Merkler, D.J.
Identification of an arylalkylamine N-acyltransferase from Drosophila melanogaster that catalyzes the formation of long-chain N-acylserotonins
FEBS Lett.
588
594-599
2014
Drosophila melanogaster (Q9VMG0)
Manually annotated by BRENDA team
Byeon, Y.; Yool Lee, H.; Choi, D.W.; Back, K.
Chloroplast-encoded serotonin N-acetyltransferase in the red alga Pyropia yezoensis: gene transition to the nucleus from chloroplasts
J. Exp. Bot.
66
709-717
2015
Neopyropia yezoensis
Manually annotated by BRENDA team
Paulin, C.H.; Cazamea-Catalan, D.; Zilberman-Peled, B.; Herrera-Perez, P.; Sauzet, S.; Magnanou, E.; Fuentes, M.; Gothilf, Y.; Munoz-Cueto, J.A.; Falcon, J.; Besseau, L.
Subfunctionalization of arylalkylamine N-acetyltransferases in the sea bass Dicentrarchus labrax: two-ones for one two
J. Pineal Res.
59
354-364
2015
Dicentrarchus labrax (A0A0K1H4R1), Dicentrarchus labrax (B9TU30), Dicentrarchus labrax (B9TU31), Dicentrarchus labrax
Manually annotated by BRENDA team
Lee, H.R.; Kim, T.D.; Kim, H.J.; Jung, Y.; Lee, D.; Lee, K.H.; Kim, D.Y.; Woo, K.C.; Kim, K.T.
Heterogeneous ribonucleoprotein R regulates arylalkylamine N-acetyltransferase synthesis via internal ribosomal entry site-mediated translation in a circadian manner
J. Pineal Res.
59
518-529
2015
Rattus norvegicus (Q64666)
Manually annotated by BRENDA team
Ahn, J.H.; Park, J.H.; Kim, I.H.; Lee, J.C.; Yan, B.C.; Yong, M.S.; Lee, C.H.; CHoi, J.H.; Yoo, K.Y.; Hwang, I.K.; Moon, S.M.; Shin, H.C.; Won, M.H.
Comparison of arylalkylamine N-acetyltransferase and melatonin receptor type 1B immunoreactivity between young adult and aged canine spinal cord
J. Vet. Sci.
15
335-342
2014
Canis lupus familiaris
Manually annotated by BRENDA team
Nisembaum, L.G.; Tinoco, A.B.; Moure, A.L.; Alonso Gomez, A.L.; Delgado, M.J.; Valenciano, A.I.
The arylalkylamine-N-acetyltransferase (AANAT) acetylates dopamine in the digestive tract of goldfish: a role in intestinal motility
Neurochem. Int.
62
873-880
2013
Carassius auratus (G1CSA9), Carassius auratus
Manually annotated by BRENDA team
Byeon, Y.; Back, K.
Melatonin production in Escherichia coli by dual expression of serotonin N-acetyltransferase and caffeic acid O-methyltransferase
Appl. Microbiol. Biotechnol.
100
6683-6691
2016
Ovis aries (Q29495)
Manually annotated by BRENDA team
Shin, S.; Choe, J.
Crystal structure of Pseudomonas aeruginosa N-acetyltransferase PA4534
Biochem. Biophys. Res. Commun.
487
236-240
2017
Pseudomonas aeruginosa (Q9HVP3), Pseudomonas aeruginosa DSM 22644 (Q9HVP3)
Manually annotated by BRENDA team
Premabati, Y.; Singh, K.; Gupta, B.
Inverse relationship between diurnal rhythms in plasma levels of thyroid hormones and pineal arylalkylamine-N-acetyltransferase (AANAT) activity in an air-breathing fish, Clarias gariepinus
Biol. Rhythm. Res.
49
201-214
2018
Clarias gariepinus
-
Manually annotated by BRENDA team
Aboalroub, A.A.; Zhang, Z.; Keramisanou, D.; Gelis, I.
Backbone resonance assignment of an insect arylalkylamine N-acetyltransferase from Bombyx mori reveals conformational heterogeneity
Biomol. NMR Assign.
11
105-109
2017
Bombyx mori
Manually annotated by BRENDA team
Hwang, O.J.; Back, K.
Hwang, O.; Back, K. Simultaneous suppression of two distinct serotonin N-Acetyltransferase isogenes by RNA interference leads to severe decreases in melatonin and accelerated seed deterioration in rice
Biomolecules
10
141
2020
Oryza sativa Japonica Group (Q5KQI6), Oryza sativa Japonica Group (Q6Z1Y6)
Manually annotated by BRENDA team
Lee, H.; Lee, K.; Back, K.
Knockout of Arabidopsis serotonin N-acetyltransferase-2 reduces melatonin levels and delays flowering
Biomolecules
9
712
2019
Arabidopsis thaliana
Manually annotated by BRENDA team
Noh, M.Y.; Koo, B.; Kramer, K.J.; Muthukrishnan, S.; Arakane, Y.
Arylalkylamine N-acetyltransferase 1 gene (TcAANAT1) is required for cuticle morphology and pigmentation of the adult red flour beetle, Tribolium castaneum
Insect Biochem. Mol. Biol.
79
119-129
2016
Tribolium castaneum (A0A1J0AHX8), Tribolium castaneum
Manually annotated by BRENDA team
Alkozi, H.; de Lara, M.; Sanchez-Naves, J.; Pintor, J.
TRPV4 stimulation induced melatonin secretion by increasing arylalkymine N-acetyltransferase (AANAT) protein level
Int. J. Mol. Sci.
18
746
2017
Homo sapiens (Q16613), Homo sapiens
Manually annotated by BRENDA team
Wadas, B.; Borjigin, J.; Huang, Z.; Oh, J.H.; Hwang, C.S.; Varshavsky, A.
Degradation of serotonin N-acetyltransferase, a circadian regulator, by the N-end rule pathway
J. Biol. Chem.
291
17178-17196
2016
Homo sapiens (Q16613), Homo sapiens, Rattus norvegicus (Q64666)
Manually annotated by BRENDA team
Byeon, Y.; Lee, H.; Back, K.
Cloning and characterization of the serotonin N-acetyltransferase-2 gene (SNAT2) in rice (Oryza sativa)
J. Pineal Res.
61
198-207
2016
Oryza sativa (Q6Z1Y6)
Manually annotated by BRENDA team
Lee, K.; Back, K.
Overexpression of rice serotonin N-acetyltransferase 1 in transgenic rice plants confers resistance to cadmium and senescence and increases grain yield
J. Pineal Res.
62
e12392
2017
Oryza sativa Japonica Group (Q5KQI6)
Manually annotated by BRENDA team
Lee, K.; Hwang, O.J.; Reiter, R.J.; Back, K.
Flavonoids inhibit both rice and sheep serotonin N-acetyltransferases and reduce melatonin levels in plants
J. Pineal Res.
65
e12512
2018
Oryza sativa, Ovis aries (Q29495), Ovis aries
Manually annotated by BRENDA team
Aboalroub, A.A.; Bachman, A.B.; Zhang, Z.; Keramisanou, D.; Merkler, D.J.; Gelis, I.
Acetyl group coordinated progression through the catalytic cycle of an arylalkylamine N-acetyltransferase
PLoS ONE
12
e0177270
2017
Bombyx mori
Manually annotated by BRENDA team
Pan, Q.; Zhao, F.; Ye, B.
Eis, a novel family of arylalkylamine N-acetyltransferase (EC 2.3.1.87)
Sci. Rep.
8
2435
2018
Saccharopolyspora erythraea, Mycolicibacterium smegmatis (A0QY29), Mycolicibacterium smegmatis, Mycobacterium tuberculosis (P9WFK7), Mycobacterium tuberculosis, Mycolicibacterium smegmatis ATCC 700084 (A0QY29), Mycobacterium tuberculosis ATCC 25618 (P9WFK7)
Manually annotated by BRENDA team