2.3.1.87: aralkylamine N-acetyltransferase

This is an abbreviated version!
For detailed information about aralkylamine N-acetyltransferase, go to the full flat file.

Word Map on EC 2.3.1.87

2.3.1.87

melatonin

pineal

rhythm

circadian

clock

retina

night

nocturnal

norepinephrine

hiomt

pinealocytes

arylalkylamine-n-acetyltransferase

hydroxyindole-o-methyltransferase

photoreceptors

oscillator

n-acetylserotonin

diurnal

suprachiasmatic

photoperiodic

snats

light-dark

sodium-coupled

adrenergic

tryptamine

entrain

photoreceptive

synthesis

n-acetyl-5-methoxytryptamine

gcn5-related

photic

zeitgeber

clockwork

day-night

octopamine

night-time

clock-controlled

medicine

analysis

ne-stimulated

hydroxyindole

meaib

melatoninergic

rhythm-generating

extrapineal

slc38a2

Reaction

Synonyms

AA-NAT, AANAT, AANAT1, AANAT2, AANAT3, AANATL7, AATNATL2, acetyl-CoA:aralkylamine N-acetyltransferase, acetyltransferase, arylalkylamine N-, arylalkylamine N-acetyltransferase, arylalkylamine N-acetyltransferase 1, arylalkylamine N-acetyltransferase 1a, arylalkylamine N-acetyltransferase 1b, arylalkylamine N-acetyltransferase 2, arylalkylamine N-acetyltransferase like 7, arylalkylamine N-acetyltransferase-2, Bm-iAANAT, Eis, hAANAT, More, MSMEG_3513, N-acetyltransferase, NAT, oAANAT, PA4534, PaaNAT, Rv2416c, serotonin acetylase, serotonin acetyltransferase, serotonin N-acetyltransferase, serotonin-N-acetyltransferase, SNA, SNAT, SNAT1, SNAT2

ECTree

2 Transferases

2.3 Acyltransferases

2.3.1 Transferring groups other than aminoacyl groups

2.3.1.87 aralkylamine N-acetyltransferase

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Results	in table
14	Activating Compound
95	AA Sequence
3	Application
1	CAS Registry Number
36	Cloned(Commentary)
14	Cofactor
4	Crystallization (Commentary)
225	Disease/ Diagnostics
5	Expression
49	General Information
11	General Stability
42	IC50 Value
88	Inhibitors
54	kcat/KM [mM/s]
2	Ki Value [mM]
182	KM Value [mM]
8	Localization
3	Metals/Ions
21	Molecular Weight [Da]
33	Natural Substrates/ Products (Substrates)
126	Organism
6	Pathway
41	PDB ID
18	pH Optimum
2	pH Range
1	pI Value
7	Posttranslational Modification
37	Protein Variants
13	Purification (Commentary)
12	Reaction
1	Reaction Type
124	Reference
119	Source Tissue
11	Specific Activity [micromol/min/mg]
4	Storage Stability
289	Substrates and Products (Substrate)
22	Subunits
120	Synonyms
1	Systematic Name
18	Temperature Optimum [°C]
10	Temperature Range [°C]
10	Temperature Stability [°C]
68	Turnover Number [1/s]

IC50 Value

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IC50 Value on EC 2.3.1.87 - aralkylamine N-acetyltransferase

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0.00039

2-bromo-N-[2-(5-fluoro-1-benzothien-3-yl)ethyl]acetamide

Homo sapiens

IC50: 0.00039 mM

658645

0.00041 - 0.0008

acetyl-CoA-tryptamine

3 entries

0.00128 - 0.0051

bromoacetyltryptamine

4 entries

0.16 - 0.26

Melatonin

2 entries

0.00225

methyl 3-[2-[(bromoacetyl)amino]ethyl]-1-benzothiophene-5-carboxylate

Homo sapiens

IC50: 0.00225 mM

658645

0.68

N-acetylserotonin

Sparus aurata

Q68SL6, Q68SL7

IC50: 0.68 mM

658812

0.0087

N-[2-(2-benzyl-5-methoxy-benzofuran-3-yl)ethyl]iodoacetamide

Homo sapiens

IC50: 0.0087 mM

658645

0.001

N-[2-(2-phenyl-benzo [b]thiophen-3-yl)ethyl]bromoacetamide

Homo sapiens

IC50: 0.001 mM

658645

0.0006

N-[2-(3-ethyl-7-methoxy-napht-1-yl)ethyl]iodoacetamide

Homo sapiens

IC50: 0.0006 mM

658645

0.00378

N-[2-(5-bromo-benzo[b]thiophen-3-yl)ethyl]bromoacetamide

Homo sapiens

IC50: 0.00378 mM

658645

0.00018

N-[2-(5-chloro-benzo[b]thiophen-3-yl)ethyl]bromoacetamide

Homo sapiens

IC50: 0.00018 mM

658645

0.002

N-[2-(5-ethyl-1-benzothien-3-yl)ethyl]-2-iodoacetamide

Homo sapiens

IC50: 0.002 mM

658645

0.00071

N-[2-(5-ethyl-benzo[b]thiophen-3-yl)ethyl]bromoacetamide

Homo sapiens

IC50: 0.00071 mM

658645

0.0056

N-[2-(5-fluoro-1H-indol-3-yl)ethyl]bromoacetamide

Homo sapiens

IC50: 0.0056 mM

658645

0.00018

N-[2-(5-hydroxy-benzo[b]thiophen-3-yl)ethyl]bromoacetamide

Homo sapiens

IC50: 0.00018 mM

658645

0.1

N-[2-(7-ethyl-1,2,3,4-tetrahydronapht-1-yl)ethyl]iodooacetamide

Homo sapiens

IC50: above 0.1 mM

658645

0.00177

N-[2-(7-ethyl-napht-1-yl)ethyl]-bromoacetamide

Homo sapiens

IC50: 0.00177 mM

658645

0.00072

N-[2-(7-hydroxy-naphth-1-yl)ethyl]bromoacetamide

Homo sapiens

IC50: 0.00072 mM

658645

0.045

N-[2-(7-methoxy-3-(3-trifluoromethylphenyl)-napht-1-yl)ethyl]iodoacetamide

Homo sapiens

IC50: 0.045 mM

658645

0.1

N-[2-(7-methoxy-8-propenyl-napht-1-yl)ethyl]-iodoacetamide

Homo sapiens

IC50: above 0.1 mM

658645

0.002

N-[2-(7-methoxy-napht-1-yl)ethyl]bromoacetamide

Homo sapiens

IC50: 0.002 mM

658645

0.0042

N-[2-(7-propoxy-napht-1-yl)ethyl]iodoacetamide

Homo sapiens

IC50: 0.0042 mM

658645

0.0013 - 0.0024

S 20251

3 entries

0.005 - 0.031

S 23823

2 entries

0.00026 - 0.00072

S 27244

3 entries

0.00018 - 0.0004

S 27481

3 entries

0.00073 - 0.0056

S 28036

3 entries