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Information on EC 2.5.1.16 - spermidine synthase

for references in articles please use BRENDA:EC2.5.1.16
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IUBMB Comments
The enzymes from the plant Glycine max and from mammalia are highly specific for putrescine as the amine acceptor [2,7]. The enzymes from the bacteria Escherichia coli and Thermotoga maritima prefer putrescine but are more tolerant towards other amine acceptors, such as spermidine and cadaverine [5,6]. cf. EC 2.5.1.22 (spermine synthase) and EC 2.5.1.23 (sym-norspermidine synthase).
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
aminopropyltransferase, spds2, spdsyn, spd synthase, mdspds1, pgspd, putrescine aminopropyltransferase, spermidine synthase 1, spermidine synthetase, aminopropyltransferase spermidine synthase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-adenosyl 3-(methylsulfanyl)propylamine + putrescine = S-methyl-5'-thioadenosine + spermidine
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