Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Trypanosoma brucei |
Protein Variants | Comment | Organism |
---|---|---|
additional information | downregulation by RNAi correlates with a decrease in intracellular spermidine and cessation of growth in bloodstream form parasites. Phenotype can be rescued by expression of Leishmania major spermidine synthase gene, but not by addition of spermidine to the growth medium | Trypanosoma brucei |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00009 | - |
S-adenosylmethioninamine | pH 7.2, 37°C | Trypanosoma brucei | |
0.205 | - |
putrescine | pH 7.2, 37°C | Trypanosoma brucei |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
33000 | - |
x * 33000, calculated, x * 37000, SDS-PAGE | Trypanosoma brucei |
37000 | - |
x * 33000, calculated, x * 37000, SDS-PAGE | Trypanosoma brucei |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma brucei | Q38EH6 | - |
- |
Purification (Comment) | Organism |
---|---|
recombinant enzyme | Trypanosoma brucei |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
putrescine + S-adenosylmethioninamine | - |
Trypanosoma brucei | spermidine + 5'-methylthioadenosine | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 33000, calculated, x * 37000, SDS-PAGE | Trypanosoma brucei |
Synonyms | Comment | Organism |
---|---|---|
SpSyn | - |
Trypanosoma brucei |