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EC 2.3.1.74 Details
EC number
2.3.1.74
Accepted name
chalcone synthase
Reaction
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2
Other name(s)
naringenin-chalcone synthase, flavanone synthase, 6′-deoxychalcone synthase, chalcone synthetase, DOCS, CHS
Systematic name
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
CAS registry number
56803-04-4
Comment
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
History
created 1984, modified 2018
EC Tree
2.3.1.55 created 1976, deleted 1999
2.3.1.120 created 1990, deleted 1992
2.3.1.124 created 1990, deleted 1992