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EC 2.3.1.225 Details
EC number
2.3.1.225
Accepted name
protein S-acyltransferase
Reaction
palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA
Other name(s)
DHHC palmitoyl transferase, S-protein acyltransferase, G-protein palmitoyltransferase
Systematic name
palmitoyl-CoA:[protein]-L-cysteine S-palmitoyltransferase
Comment
The enzyme catalyses the posttranslational protein palmitoylation that plays a role in protein-membrane interactions, protein trafficking, and enzyme activity. Palmitoylation increases the hydrophobicity of proteins or protein domains and contributes to their membrane association.
History
created 2013
EC Tree
2.3.1.55 created 1976, deleted 1999
2.3.1.120 created 1990, deleted 1992
2.3.1.124 created 1990, deleted 1992