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EC 2.3.1.29 Details
EC number
2.3.1.29
Accepted name
glycine C-acetyltransferase
Reaction
acetyl-CoA + glycine = CoA + L-2-amino-3-oxobutanoate
Other name(s)
2-amino-3-ketobutyrate CoA ligase,
2-amino-3-ketobutyrate coenzyme A ligase,
2-amino-3-ketobutyrate-CoA ligase,
glycine acetyltransferase,
aminoacetone synthase,
aminoacetone synthetase,
KBL,
AKB ligase
Systematic name
acetyl-CoA:glycine C-acetyltransferase
CAS registry number
37257-11-7
Comment
This is a pyridoxal-phosphate-dependent enzyme that acts in concert with EC 1.1.1.103, L-threonine 3-dehydrogenase, in the degradation of threonine to form glycine [3]. This threonine degradation pathway is common to prokaryotic and eukaryotic cells and the two enzymes involved form a complex [4].
History
created 1972
EC Tree
2.3.1.55 created 1976, deleted 1999
2.3.1.120 created 1990, deleted 1992
2.3.1.124 created 1990, deleted 1992