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Information on EC 2.3.1.74 - chalcone synthase

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EC Tree
     2 Transferases
         2.3 Acyltransferases
             2.3.1 Transferring groups other than aminoacyl groups
                2.3.1.74 chalcone synthase
IUBMB Comments
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
6'-deoxychalcone synthase, anther-specific chalcone synthase-like enzyme, ASCL1, ASCL2, chalcone synthase, chalcone synthase 6, chalcone synthase 7, chalcone synthase C2-Idf-I, chalcone synthase C2-Idf-II, chalcone synthetase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2
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