EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
2.3.1.51 | 1-acylglycerol-3-phosphate O-acyltransferase |
adipocyte |
- |
671597, 756108, 756599 |
2.3.1.51 | 1-acylglycerol-3-phosphate O-acyltransferase |
adipocyte |
isozyme AGPAT2 |
674530 |
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
adipocyte |
by retrieving LPCAT3 expression pattern from Genevestigator |
688774 |
3.1.1.47 | 1-alkyl-2-acetylglycerophosphocholine esterase |
adipocyte |
- |
653094 |
2.7.1.67 | 1-phosphatidylinositol 4-kinase |
adipocyte |
- |
641796, 676001 |
2.7.1.150 | 1-phosphatidylinositol-3-phosphate 5-kinase |
adipocyte |
- |
660790 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
adipocyte |
- |
668379, 669504, 697625, 700121, 700179, 700180, 712594, 740806 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
adipocyte |
epididymal fat, presence of a functional glucose-6-phosphate-transporter hexose-6-phosphate dehydrogenase 11beta-hydroxysteroid dehydrogenase type 1 system |
692078 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
adipocyte |
methionine restriction induces isoform 11beta-HSD1 activity in all types of adipose tissue examined, correlating with increased tissue corticosterone. Inverse relationship between 11beta-HSD1 activity and adipocyte size is observed. Methionine restriction additionally increases adipose triglyceride lipase and acetyl-coenzyme A carboxylase protein levels |
688225 |
1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
adipocyte |
- |
668379 |
1.3.1.48 | 13,14-dehydro-15-oxoprostaglandin 13-reductase |
adipocyte |
- |
687562 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
adipocyte |
- |
699843 |
2.3.1.22 | 2-acylglycerol O-acyltransferase |
adipocyte |
- |
757377 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
adipocyte |
- |
716435 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
adipocyte |
primary |
668230 |
1.1.1.51 | 3(or 17)beta-hydroxysteroid dehydrogenase |
adipocyte |
real-time RT-PCR expression 17beta-HSD type 2 analysis |
741000 |
6.2.1.16 | acetoacetate-CoA ligase |
adipocyte |
- |
-, 691065, 702149, 744226 |
6.2.1.16 | acetoacetate-CoA ligase |
adipocyte |
AACS mRNA is preferentially detected in mature adipocytes but not in preadipocytes. AACS mRNA expression in primary preadipocytes increases during the adipocyte differentiation |
660915 |
6.4.1.2 | acetyl-CoA carboxylase |
adipocyte |
- |
666733 |
1.3.3.6 | acyl-CoA oxidase |
adipocyte |
- |
671758 |
3.1.1.23 | acylglycerol lipase |
adipocyte |
- |
94261, 94269 |
3.4.24.86 | ADAM 17 endopeptidase |
adipocyte |
adipose tissue |
639013 |
3.4.24.81 | ADAM10 endopeptidase |
adipocyte |
- |
708278 |
3.4.24.B10 | ADAM12 endopeptidase |
adipocyte |
- |
680191 |
4.6.1.1 | adenylate cyclase |
adipocyte |
- |
34802 |
3.1.4.39 | alkylglycerophosphoethanolamine phosphodiesterase |
adipocyte |
- |
729338 |
3.1.4.39 | alkylglycerophosphoethanolamine phosphodiesterase |
adipocyte |
Immunocyto-fluorescence microscopy reveals that ATX is detected in 3T3F442A adipocytes and is almost undetectable in 3T3F442A preadipocytes. 3T3F442A mouse preadipose cell line |
678439 |
1.3.99.23 | all-trans-retinol 13,14-reductase |
adipocyte |
- |
700994, 763507 |
2.3.1.108 | alpha-tubulin N-acetyltransferase |
adipocyte |
acetylation of alpha-tubulin is up-regulated during adipogenesis, and adipocyte development is dependent on alpha-tubulin acetylation |
735631 |
1.13.11.31 | arachidonate 12-lipoxygenase |
adipocyte |
- |
743718 |
1.13.11.33 | arachidonate 15-lipoxygenase |
adipocyte |
- |
742239, 743718 |
3.1.8.1 | aryldialkylphosphatase |
adipocyte |
PON1 |
692441 |
2.6.1.1 | aspartate transaminase |
adipocyte |
- |
674846 |
2.6.1.1 | aspartate transaminase |
adipocyte |
differentiated from 3T3-L1 fibroblasts |
639866 |
2.3.3.8 | ATP citrate synthase |
adipocyte |
- |
736797 |
2.7.11.15 | beta-adrenergic-receptor kinase |
adipocyte |
- |
661684, 724817 |
1.13.11.63 | beta-carotene 15,15'-dioxygenase |
adipocyte |
- |
728342, 728552 |
2.4.3.1 | beta-galactoside alpha-(2,6)-sialyltransferase |
adipocyte |
- |
759485 |
1.14.15.18 | calcidiol 1-monooxygenase |
adipocyte |
- |
699840 |
3.4.22.B30 | calpain 10 |
adipocyte |
- |
731226 |
3.4.22.52 | calpain-1 |
adipocyte |
- |
707364 |
2.7.11.11 | cAMP-dependent protein kinase |
adipocyte |
- |
671678, 693043, 694155 |
3.4.17.12 | carboxypeptidase M |
adipocyte |
- |
697395 |
2.3.1.21 | carnitine O-palmitoyltransferase |
adipocyte |
- |
486560, 486577 |
3.4.22.38 | cathepsin K |
adipocyte |
CTSK is active mainly in the early stages of adipogenesis |
697619 |
3.4.22.27 | cathepsin S |
adipocyte |
- |
668538, 699142 |
2.7.11.12 | cGMP-dependent protein kinase |
adipocyte |
- |
737600 |
3.4.21.46 | complement factor D |
adipocyte |
- |
755129 |
4.4.1.1 | cystathionine gamma-lyase |
adipocyte |
- |
690781 |
1.13.11.20 | cysteine dioxygenase |
adipocyte |
- |
695529 |
3.4.11.3 | cystinyl aminopeptidase |
adipocyte |
- |
-, 668760, 683048, 709666, 753943, 754109, 754445, 755404 |
5.3.3.8 | DELTA3-DELTA2-enoyl-CoA isomerase |
adipocyte |
- |
706005 |
2.7.1.74 | deoxycytidine kinase |
adipocyte |
- |
661040 |
2.7.1.113 | deoxyguanosine kinase |
adipocyte |
- |
661040 |
2.7.8.2 | diacylglycerol cholinephosphotransferase |
adipocyte |
- |
644323 |
2.3.1.20 | diacylglycerol O-acyltransferase |
adipocyte |
- |
-, 486338, 486485, 486487, 486489, 486495, 486505, 486506, 486512, 486513 |
2.3.1.20 | diacylglycerol O-acyltransferase |
adipocyte |
isolated from parametrial adipose |
486484 |
2.3.1.57 | diamine N-acetyltransferase |
adipocyte |
- |
757571 |
2.8.2.4 | estrone sulfotransferase |
adipocyte |
- |
725979 |
2.8.2.4 | estrone sulfotransferase |
adipocyte |
EST is predominantly expressed in stromal vascular cells (pre-adipocytes). Consistent with the pre-adipocyte pattern of expression, the expression of EST is dramatically reduced in differentiated 3T3-L1 cells or mature primary adipocytes |
-, 760317 |
2.7.7.14 | ethanolamine-phosphate cytidylyltransferase |
adipocyte |
- |
671816 |
2.7.7.14 | ethanolamine-phosphate cytidylyltransferase |
adipocyte |
high Pcyt2 mRNA content. Negligible amount of Pcyt2beta mRNA, high amount of Pcyt2alpha mRNA |
671816 |
2.7.8.1 | ethanolaminephosphotransferase |
adipocyte |
- |
644323 |
3.1.3.46 | fructose-2,6-bisphosphate 2-phosphatase |
adipocyte |
inducible expression of isozyme PFKFB3 |
664718 |
3.1.3.46 | fructose-2,6-bisphosphate 2-phosphatase |
adipocyte |
inducible expression of isozyme PFKFB3, visceral fat cell |
664718 |
1.11.1.9 | glutathione peroxidase |
adipocyte |
pGPx is expressed during bovine adipocyte differentiation, transcriptional control of pGPx in cattle might be carried out by C/EBPdelta |
672988 |
2.7.1.30 | glycerol kinase |
adipocyte |
There is no difference in glycerol mRNA level between control 3T3-L1 adipocytes and 3T3-L1 Aqp7-RNAi transfected adipocytes, whereas a 4fold enzymatic activation of glycerol kinase is observable in Aqp7 knockout adipocytes (activity assay: 50 mM TrisHCl, pH 7.2, 5 mM ATP, 10 mM MgCl2, 100 mM KCl, 2.5 mM DTT, 4 mM glycerol, 500 microM 3H-glycerol, for 90 min at 37°C). |
682503 |
2.3.1.15 | glycerol-3-phosphate 1-O-acyltransferase |
adipocyte |
- |
701623, 702011, 756106 |
2.3.1.15 | glycerol-3-phosphate 1-O-acyltransferase |
adipocyte |
GPAT3 mRNA is dramatically upregulated during adipocyte differentiation |
676839 |
2.3.1.15 | glycerol-3-phosphate 1-O-acyltransferase |
adipocyte |
mitochondrial acyltransferase |
486376 |
2.3.1.15 | glycerol-3-phosphate 1-O-acyltransferase |
adipocyte |
the expression of GPAT2 is downregulated when 3T3-L1 cells differentiate into adipocytes, while GPAT1, 3, and 4 are upregulated (10fold, over 60, and 5fold, respectively) |
757868 |
2.3.1.15 | glycerol-3-phosphate 1-O-acyltransferase |
adipocyte |
the expression of GPAT2 is downregulated when 3T3-L1 cells differentiate into adipocytes, while GPAT1, 3, and 4 are upregulated 10fold, over 60fold, and 5fold, respectively |
757868 |
1.1.1.8 | glycerol-3-phosphate dehydrogenase (NAD+) |
adipocyte |
- |
699948 |
2.3.1.42 | glycerone-phosphate O-acyltransferase |
adipocyte |
- |
486338, 486955, 486974 |
2.4.1.11 | glycogen(starch) synthase |
adipocyte |
3T3-L1 |
488441, 488447 |
4.6.1.14 | glycosylphosphatidylinositol diacylglycerol-lyase |
adipocyte |
- |
648771, 648772, 661039, 691540 |
3.6.5.1 | heterotrimeric G-protein GTPase |
adipocyte |
Go-alpha subunit |
644099 |
2.7.1.1 | hexokinase |
adipocyte |
very low expression |
703959 |
3.1.1.79 | hormone-sensitive lipase |
adipocyte |
- |
-, 665562, 665964, 677942, 714034, 714319, 714794 |
3.1.1.79 | hormone-sensitive lipase |
adipocyte |
adipocytes retrovirally engineered from murine embryonic fibroblasts |
680650 |
3.1.1.79 | hormone-sensitive lipase |
adipocyte |
dydrogesterone and norethisterone regulate expression of hormone-sensitive lipase in human subcutaneous abdominal adipocytes |
679453 |
3.1.1.79 | hormone-sensitive lipase |
adipocyte |
women with polycystic ovary syndrome or obesity have significantly decreased expression of hormone-sensitive lipase. Knock down of hormone-sensitive lipase by RNAi reduces basal and catecholamine-induced lipolysis. Treatment of mesenchymal stem cells with a selective inhibitor of hormone-sensitive lipase during and/or after differentiation in adipocytes reduces basal lipolysis by 50% |
677465 |
1.1.1.205 | IMP dehydrogenase |
adipocyte |
- |
702061 |
2.7.4.21 | inositol-hexakisphosphate 5-kinase |
adipocyte |
- |
738392 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
adipocyte |
- |
656247, 761047 |
5.3.3.12 | L-dopachrome isomerase |
adipocyte |
- |
728570 |
3.4.11.1 | leucyl aminopeptidase |
adipocyte |
- |
651776, 664275, 664276, 752649 |
3.3.2.6 | leukotriene-A4 hydrolase |
adipocyte |
- |
647020 |
3.1.1.34 | lipoprotein lipase |
adipocyte |
- |
-, 652702, 690827, 693527, 709009, 729291, 751275, 80891 |
6.2.1.3 | long-chain-fatty-acid-CoA ligase |
adipocyte |
- |
662593, 662994, 714678 |
3.4.24.B5 | matrix metalloproteinase-15 |
adipocyte |
- |
753384 |
3.4.24.B5 | matrix metalloproteinase-15 |
adipocyte |
of mammary gland |
753384 |
1.3.8.7 | medium-chain acyl-CoA dehydrogenase |
adipocyte |
- |
656794 |
3.4.24.80 | membrane-type matrix metalloproteinase-1 |
adipocyte |
- |
753384 |
3.4.24.80 | membrane-type matrix metalloproteinase-1 |
adipocyte |
of mammary gland |
753384 |
1.4.3.4 | monoamine oxidase |
adipocyte |
- |
689376 |
1.4.3.4 | monoamine oxidase |
adipocyte |
in human subcutaneous adipose tissue, the adipocyte-enriched fraction exhibits seven-fold higher amine oxidase activity and contains 3- to 7-fold higher levels of mRNAs encoded by MAO-A and MAO-B genes than the stroma-vascular fraction. MAO-A gene accounts for the majority of the respective MAO and SSAO activities in human adipose tissue. Most of the SSAO and MAO found in adipose tissue originated from mature adipocytes |
685418 |
1.4.3.4 | monoamine oxidase |
adipocyte |
most of the monoamine oxidase found in adipose tissue originates from mature adipocytes |
688255 |
1.4.3.4 | monoamine oxidase |
adipocyte |
SSAO inhibition is not sufficient to impair fat deposition. Combined MAO and SSAO inhibition limits adiposity in non-obese as well as in obese rats |
689377 |
2.1.1.348 | mRNA m6A methyltransferase |
adipocyte |
- |
757661 |