Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

2.4.1.90: N-acetyllactosamine synthase

This is an abbreviated version!
For detailed information about N-acetyllactosamine synthase, go to the full flat file.

Word Map on EC 2.4.1.90

Reaction

UDP-alpha-D-galactose
+
N-acetyl-D-glucosamine
=
UDP
+
N-acetyllactosamine

Synonyms

acetyllactosamine synthetase, B4GALT1, B4GALT3, B4GalT5, beta 1,4 galactosyltransferase I, beta 1,4-galactosyltransferase 1, beta 1,4GalT II, beta 1,4GTI, beta(1,4)-galactosyltransferase, beta(1,4)-GT, beta(1-4)galactosyltransferase, beta-1,4-galactosyltransferase, beta-1,4-galactosyltransferase 1, beta-1,4-galactosyltransferase III, beta-1,4-galactosyltransferase IV, beta-1,4-galactosyltransferase-1, beta-1,4-galactosyltransferase-I, beta-1,4-galactosyltransferase-V, beta-1,4-GalT, beta-1,4-GalT-I, beta-1,4-GalT-V, beta-1,4-GT-IV, beta-1,4-N-acetylgalactosaminyltransferase, beta-N-acetylglucosaminide beta1-4-galactosyltransferase, beta1,4-Gal-transferase T1, beta1,4-galactosyltransferase, beta1,4-galactosyltransferase I, beta1,4-galactosyltransferase II, beta1,4-galactosyltransferase V, beta1,4-galactosyltransferase-1, beta1,4-galactosyltransferase-7, beta1,4-galactosyltransferase-I, beta1,4-GT, beta1,4GalT II, beta1,4GalTV, beta1-4-galactosyltransferase, beta1-4GalT, beta4Gal-T, beta4Gal-T1, beta4Gal-T7, beta4GalT, beta4GalT1, betaGALT1, beta[1-4]GalT, EC 2.4.1.98, Gal-T, galactosyltransferase, uridine diphosphogalactose-acetylglucosamine, GalNAcT, GALT, GalT1, GalT7, GalTase, GalTase-I, GTase, Hp1-4GalT, lactosamine synthase, lactosamine synthetase, lactose synthetase A protein, lactosylceramide synthase, More, N-acetyllactosamine synthetase, NAL synthetase, NmLgtB, UDP-beta-1,4-galactosyltransferase, UDP-Gal:betaGlcNAc beta-1,4-galactosyltransferase, polypeptide 5, UDP-Gal:N-acetylglucosamine beta1-4-galactosyltransferase, UDP-galactose N-acetylglucosamine beta-4-galactosyltransferase, UDP-galactose-acetylglucosamine galactosyltransferase, UDP-galactose-N-acetylglucosamine beta-1,4-galactosyltransferase, UDP-galactose-N-acetylglucosamine galactosyltransferase, UDP-galactose/N-acetylglucosamine beta1,4 galactosyltransferase, UDP-galactose: N-acetylglucosamine beta 1-4 galactosyltransferase, UDP-galactose:N-acetylglucosaminide beta1-4-galactosyltransferase, UDPgalactose-N-acetylglucosamine beta-D-galactosyltransferase, UDPgalactose:N-acetylglucosaminyl(beta1-4)galactosyltransferase, uridine diphosphogalactose-acetylglucosamine galactosyltransferase

ECTree

     2 Transferases
         2.4 Glycosyltransferases
             2.4.1 Hexosyltransferases
                2.4.1.90 N-acetyllactosamine synthase

Reference

Reference on EC 2.4.1.90 - N-acetyllactosamine synthase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Paquet, M.R.; Moscarello, M.A.
A kinetic comparison of partially purified rat liver Golgi and rat serum galactosyltransferases
Biochem. J.
218
745-751
1984
Bos taurus, Rattus norvegicus
Manually annotated by BRENDA team
Ramakrishnan, B.; Qasba, P.K.
Crystal structure of lactose synthase reveals a large conformational change in its catalytic component, the beta1,4-galactosyltransferase-I
J. Mol. Biol.
310
205-218
2001
Bos taurus
Manually annotated by BRENDA team
Blanken, W.M.; van den Eijnden, D.H.
Biosynthesis of terminal Gal alpha (1-3)Gal beta 1-4)GlcNAc-R oligosaccharide sequences on glycoconjugates. Purification and acceptor specificity of a UDP-Gal:N-acetyllactosaminide alpha(1-3)galactosyltransferase from calf thymus
J. Biol. Chem.
260
12927-12934
1985
Bos taurus
Manually annotated by BRENDA team
Smith, C.A.; Brew, K.
Isolation and characteristics of galactosyltransferase from Golgi membranes of lactating sheep mammary glands
J. Biol. Chem.
252
7294-7299
1977
Ovis aries
Manually annotated by BRENDA team
Helting, T.; Erbing, B.
Galactosyltransfer in mouse mastocytoma: purification and properties of N-acetyllactosamine synthetase
Biochim. Biophys. Acta
293
94-104
1973
Mus musculus
Manually annotated by BRENDA team
Schachter, H.; Jabbal, I.; Hudgin, R.L.; Pinteric, L.
Intracellular localization of liver sugar nucleotide glycoprotein glycosyltransferases in a Golgi-rich fraction
J. Biol. Chem.
245
1090-1100
1970
Rattus norvegicus
Manually annotated by BRENDA team
Deshmukh, D.S.; Bear, W.D.; Soifer, D.
Isolation and characterization of an enriched Golgi fraction from rat brain
Biochim. Biophys. Acta
542
284-295
1978
Rattus norvegicus
Manually annotated by BRENDA team
Nakazawa, K.; Furukawa, K.; Kobata, A.; Narimatsu, H.
Characterization of a murine beta 1-4 galactosyltransferase expressed in COS-1 cells
Eur. J. Biochem.
196
363-368
1991
Mus musculus
Manually annotated by BRENDA team
Nakazawa, K.; Ando, T.; Kimura, T.; Narimatsu, H.
Cloning and sequencing of a full-length cDNA of mouse N-acetylglucosamine (beta 1-4)galactosyltransferase
J. Biochem.
104
165-168
1988
Mus musculus
Manually annotated by BRENDA team
Shaper, N.L.; Hollis, G.F.; Douglas, J.G.; Kirsch, I.R.; Shaper, J.H.
Characterization of the full length cDNA for murine beta-1,4-galactosyltransferase. Novel features at the 5-end predict two translational start sites at two in-frame AUGs
J. Biol. Chem.
263
10420-10428
1988
Mus musculus
Manually annotated by BRENDA team
Shaper, N.L.; Shaper, J.H.; Meuth, J.L.; Fox, J.L.; Chang, H.; Kirsch, I.R.; Hollis, G.F.
Bovine galactosyltransferase: identification of a clone by direct immunological screening of a cDNA expression library
Proc. Natl. Acad. Sci. USA
83
1573-1577
1986
Bos taurus
Manually annotated by BRENDA team
Shaper, N.L.; Wright, W.W.; Shaper, J.H.
Murine beta 1,4-galactosyltransferase: both the amounts and structure of the mRNA are regulated during spermatogenesis
Proc. Natl. Acad. Sci. USA
87
791-795
1990
Mus musculus
Manually annotated by BRENDA team
Narimatsu, H.; Sinha, S.; Brew, K.; Okayama, H.; Qasba, P.K.
Cloning and sequencing of cDNA of bovine N-acetylglucosamine (beta 1-4)galactosyltransferase
Proc. Natl. Acad. Sci. USA
83
4720-4724
1986
Bos taurus
Manually annotated by BRENDA team
Watzele, G.; Berger, E.G.
Near identity of HeLa cell galactosyltransferase with the human placental enzyme
Nucleic Acids Res.
18
7174
1990
Homo sapiens
Manually annotated by BRENDA team
Amano, J.; Straehl, P.; Berger, E.G.; Kochibe, N.; Kobata, A.
Structures of mucin-type sugar chains of the galactosyltransferase purified from human milk. Occurrence of the ABO and Lewis blood group determinants
J. Biol. Chem.
266
11461-11477
1991
Homo sapiens
Manually annotated by BRENDA team
Yadav, S.; Brew, K.
Identification of a region of UDP-galactose:N-acetylglucosamine beta 4-galactosyltransferase involved in UDP-galactose binding by differential labeling
J. Biol. Chem.
265
14163-14169
1990
Bos taurus
Manually annotated by BRENDA team
D'Agostaro, G.; Bendiak, B.; Tropak, M.
Cloning of cDNA encoding the membrane-bound form of bovine beta 1,4-galactosyltransferase
Eur. J. Biochem.
183
211-217
1989
Bos taurus
Manually annotated by BRENDA team
Hollis, G.F.; Douglas, J.G.; Shaper, N.L.; Shaper, J.H.; Stafford-Hollis, J.M.; Evans, R.J.; Kirsch, I.R.
Genomic structure of murine beta-1,4-galactosyltransferase
Biochem. Biophys. Res. Commun.
162
1069-1075
1989
Mus musculus
Manually annotated by BRENDA team
Mengle-Gaw, L.; McCoy-Haman, M.F.; Tiemeier, D.C.
Genomic structure and expression of human beta-1,4-galactosyltransferase
Biochem. Biophys. Res. Commun.
176
1269-1276
1991
Homo sapiens
Manually annotated by BRENDA team
Krezdorn, C.H.; Watzele, G.; Kleene, R.B.; Ivanov, S.X.; Berger, E.G.
Purification and characterization of recombinant human beta 1-4 galactosyltransferase expressed in Saccharomyces cerevisiae
Eur. J. Biochem.
212
113-120
1993
Homo sapiens
Manually annotated by BRENDA team
Kawano, J.i.; Oinuma, T.; Nakayama, T.; Suganuma, T.
Characterization of beta 1->4 galactosyltransferase purified from rat liver microsomes
J. Biochem.
111
568-572
1992
Rattus norvegicus
Manually annotated by BRENDA team
Bendiak, B.; Ward, L.D.; Simpson, R.J.
Proteins of the Golgi apparatus. Purification to homogeneity, N-terminal sequence, and unusually large Stokes radius of the membrane-bound form of UDP-galactose:N-acetylglucosamine beta 1-4galactosyltransferase from rat liver
Eur. J. Biochem.
216
405-417
1993
Rattus norvegicus
Manually annotated by BRENDA team
Mitranic, M.M.; Moscarello, M.A.
The influence of various lipids on the activity of bovine milk galactosyltransferase
Can. J. Biochem.
58
809-814
1980
Bos taurus
Manually annotated by BRENDA team
Weiser, M.M.; Majumdar, S.; Wilson, J.R.; Luther, R.
Distribution, purification and characterization of rat intestinal UDPgalactose: N-acetylglucosaminyl(beta 1->4)galactosyltransferase
Biochim. Biophys. Acta
924
323-331
1987
Rattus norvegicus
Manually annotated by BRENDA team
Clark, P.E.; Moscarello, M.A.
The modulating effects of lipids on purified rat liver Golgi galactosyltransferase
Biochim. Biophys. Acta
859
143-150
1986
Rattus norvegicus
Manually annotated by BRENDA team
Paquet, M.R.; Narasimhan, S.; Schachter, H.; Moscarello, M.A.
Branch specificity of purified rat liver Golgi UDP-galactose: N-acetylglucosamine beta-1,4-galactosyltransferase. Preferential transfer of of galactose on the GlcNAc beta 1,2-Man alpha 1,3-branch of a complex biantennary Asn-linked oligosaccharide
J. Biol. Chem.
259
4716-4721
1984
Rattus norvegicus
Manually annotated by BRENDA team
Russo, R.N.; Shaper, N.L.; Taatjes, D.J.; Shaper, J.H.
Beta 1,4-galactosyltransferase: a short NH2-terminal fragment that includes the cytoplasmic and transmembrane domain is sufficient for Golgi retention
J. Biol. Chem.
267
9241-9247
1992
Bos taurus
Manually annotated by BRENDA team
Blanken, W.M.; Hooghwinkel, G.J.M.; van den Eijnden, D.H.
Biosynthesis of blood-group I and i substances. Specificity of bovine colostrum beta-N-acetyl-D-glucosaminide beta 1-4 galactosyltransferase
Eur. J. Biochem.
127
547-552
1982
Bos taurus
Manually annotated by BRENDA team
Berger, E.G.; Kozdrowski, I.; Weiser, M.M.; van den Eijnden, D.H.; Schiphorst, W.E.C.M.
Human serum galactosyltransferase: distinction, separation and product identification of two galactosyltransferase activities
Eur. J. Biochem.
90
213-222
1978
Homo sapiens
Manually annotated by BRENDA team
Rao, G.J.S.; Chyatte, D.; Nadler, H.L.
Enhancement of UDPgalactose: glycoprotein galactosyltransferase in cultured human skin fibroblasts by cationic polypeptides
Biochim. Biophys. Acta
541
435-443
1978
Homo sapiens
Manually annotated by BRENDA team
Fraser, I.H.; Wadden, P.; Mookerjea, S.
Purification and stabilization of galactosyltransferase from serum and lysolecithin extracted microsomes
Can. J. Biochem.
58
878-884
1980
Rattus norvegicus
Manually annotated by BRENDA team
Bouchilloux, S.
Purification by affinity chromatography and some properties of microsomal galactosyltransferase from pig thyroid
Biochim. Biophys. Acta
569
135-144
1979
Sus scrofa
Manually annotated by BRENDA team
Tsopanakis, A.D.; Herries, D.G.
Bovine galactosyl transferase. Substrate.managanese complexes and the role of manganese ions in the mechanism
Eur. J. Biochem.
83
179-188
1978
Bos taurus
Manually annotated by BRENDA team
Andree, P.J.; Berliner, L.J.
Metal ion and substrate binding to bovine galactosyltransferase
Biochemistry
19
929-934
1980
Bos taurus
Manually annotated by BRENDA team
Cummings, R.D.; Cebula, T.A.; Roth, S.
Characterization of a galactosyltransferase in plasma membrane-enriched fractions from Balb/c 3T12 cells
J. Biol. Chem.
254
1233-1240
1979
Mus musculus
Manually annotated by BRENDA team
Christner, J.E.; Distler, J.J.; Jourdian, G.W.
Biosynthesis of keratan sulfate: purification and properties of a galactosyltransferase from bovine cornea
Arch. Biochem. Biophys.
192
548-558
1979
Bos taurus
Manually annotated by BRENDA team
Fleischer, B.; Smigel, M.
Solubilization and properties of galactosyltransferase and sulfotransferase activities of Golgi membranes in Triton X-100
J. Biol. Chem.
253
1632-1638
1978
Rattus norvegicus
Manually annotated by BRENDA team
Tengowski, M.W.; Wassler, M.J.; Shur, B.D.; Schatten, G.
Subcellular localization of beta1,4-galactosyltransferase on bull sperm and its function during sperm-egg interactions
Mol. Reprod. Dev.
58
236-244
2001
Bos taurus
Manually annotated by BRENDA team
Bella, A.; Whitehead, J.S.; Kim, Y.S.
Human plasma uridine diphosphate galactose-glycoprotein galactosyltransfertase. Purification, properties and kinetics of the enzyme-catalysed reaction
Biochem. J.
167
621-628
1977
Homo sapiens
Manually annotated by BRENDA team
Fraser, I.H.; Mookerjea, S.
Purification of membrane-bound galactosyltransferase from rat liver microsomal fractions
Biochem. J.
164
541-547
1977
Rattus norvegicus
Manually annotated by BRENDA team
Rao, A.K.; Garver, F.; Mendicino, J.
Biosynthesis of the carbohydrate units of immunoglobulins. 1. Purification and properties of galactosyltransferases from swine mesentary lymph nodes
Biochemistry
15
5001-5009
1976
Sus scrofa
Manually annotated by BRENDA team
Chandler, D.K.; Silvia, J.C.; Ebner, K.E.
Inactivation of galactosyltransferase by lactoperoxidase and N-acetylimidazole
Biochim. Biophys. Acta
616
179-187
1980
Bos taurus
Manually annotated by BRENDA team
Nelson, J.D.; Jato-Rodriguez, J.J.; Mookerjea, S.
The occurrence and properties of soluble UDP-galactose:glycoprotein galactosyltransferase in human amniotic fluid
Can. J. Biochem.
52
42-50
1974
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Wagner, R.R.; Cynkin, M.A.
Glycoprotein metabolism: a UDP-galactose-glycoprotein galactosyltransferase of rat serum
Biochem. Biophys. Res. Commun.
45
57-62
1971
Rattus norvegicus
Manually annotated by BRENDA team
Fraser, I.H.; Mookerjea, S.
Studies on the purification and properties of UDP-galactose glycoprotein galactosyltransferase from rat liver and serum
Biochem. J.
156
347-355
1976
Rattus norvegicus
Manually annotated by BRENDA team
Kitchen, B.J.; Andrews, P.
Kinetic studies on the effect of uridine diphosphate galactose and manganous ions on the reaction between lactose synthetase A protein from human milk and p-hydroxymercuribenzoate
Biochem. J.
143
587-590
1974
Homo sapiens
Manually annotated by BRENDA team
Ramakrishnan, B.; Shah, P.S.; Qasba, P.K.
alpha-Lactalbumin (LA) stimulates milk beta-1,4-galactosyltransferase I (beta4Gal-T1) to transfer glucose from UDP-glucose to N-acetylglucosamine. Crystal structure of beta4Gal-T1*LA complex with UDP-Glc
J. Biol. Chem.
276
37665-37671
2001
Bos taurus
Manually annotated by BRENDA team
Nguyen, T.T.M.; Hinton, D.A.; Shur, B.D.
Expressing murine beta1,4-galactosyltransferase in HeLa cells produces a cell surface galactosyltransferase-dependent phenotype
J. Biol. Chem.
269
28000-28009
1994
Mus musculus
Manually annotated by BRENDA team
Nakazawa, K.; Furukawa, K.; Narimatsu, H.; Kobata, A.
Kinetic study of human beta-1,4-galactosyltransferase expressed in E. coli
J. Biochem.
113
747-753
1993
Homo sapiens
Manually annotated by BRENDA team
Gebhardt, S.; Bihler, S.; Schubert-Zsilaveez, M.; Riva, S.; Monti, D.; Falcone, L.; Danieli, B.
Biocatalytic generation of molecular diversity: modification of ginsenoside Rb1 by beta-1,4-galactosyltransferase and Candida antarctica lipase
Helv. Chim. Acta
85
1943-1959
2002
Bos taurus
-
Manually annotated by BRENDA team
Uehara, K.; Muramatsu, T.
Molecular cloning and characterization of beta-1,4-galactosyltransferase expressed in mouse testis
Eur. J. Biochem.
244
706-712
1997
Mus musculus
Manually annotated by BRENDA team
Sato, T.; Furukawa, K.; Bakker, H.; Van den Eijnden, D.H.; Van Die, I.
Molecular cloning of a human cDNA encoding beta-1,4-galactosyltransferase with 37% identity to mammalian UDP-Gal: GlcNAc beta-1,4-galactosyltransferase
Proc. Natl. Acad. Sci. USA
95
472-477
1998
Homo sapiens (O43286), Homo sapiens
Manually annotated by BRENDA team
Hollister, J.R.; Shaper, J.H.; Jarvis, D.L.
Stable expression of mammalian beta1,4-galactosyltransferase extends the N-glycosylation pathway in insect cells
Glycobiology
8
473-480
1998
Bos taurus
Manually annotated by BRENDA team
Hansske, B.; Thiel, C.; Lubke, T.; Hasilik, M.; Honing, S.; Peters, V.; Heidemann, P.H.; Hoffmann, G.F.; Berger, E.G.; Von Figura, K.; Korner, C.
Deficiency of UDP-galactose:N-acetylglucosamine beta-1,4-galactosyltransferase I causes the congenital disorder of glycosylation type IId
J. Clin. Invest.
109
725-733
2002
Homo sapiens
Manually annotated by BRENDA team
Ramakrishnan, B.; Qasba, P.K.
Structure-based design of beta 1,4-galactosyltransferase I (beta4Gal-T1) with equally efficient N-acetylgalactosaminyltransferase activity: point mutation broadens beta 4Gal-T1 donor specificity
J. Biol. Chem.
277
20833-20839
2002
Bos taurus
Manually annotated by BRENDA team
Herrmann, G.F.; Elling, L.; Krezdorn, C.H.; Kleene, R.; Berger, E.G.; Wandrey, C.
Use of transformed whole yeast cells expressing beta-1,4-galactosyltransferase for the synthesis of N-acetyllactosamine
Bioorg. Med. Chem. Lett.
5
673-676
1995
Bos taurus, Homo sapiens
-
Manually annotated by BRENDA team
Elling, L.; Zervosen, A.; Gallego, R.G.; Nieder, V.; Malissard, M.; Berger, E.G.; Vliegenthart, J.F.G.; Kamerling, J.P.
UDP-N-acetyl-alpha-D-glucosamine as acceptor substrate of beta-1,4-galactosyltransferase. Enzymatic synthesis of UDP-N-acetyllactosamine
Glycoconjugate J.
16
327-336
1999
Homo sapiens
Manually annotated by BRENDA team
Snow, D.M.; Shaper, J.H.; Shaper, N.L.; Hart, G.W.
Determination of beta1,4-galactosyltransferase enzymatic activity by capillary electrophoresis and laser-induced fluorescence detection
Anal. Biochem.
271
36-42
1999
Bos taurus
Manually annotated by BRENDA team
Gastinel, L.N.; Cambillau, C.; Bourne, Y.
Crystal structures of the bovine beta4galactosyltransferase catalytic domain and its complex with uridine diphosphogalactose
EMBO J.
18
3546-3557
1999
Bos taurus
Manually annotated by BRENDA team
Kawano, J.I.; Ide, S.; Oinuma, T.; Suganuma, T.
Regional distribution of beta1-4 galactosyltransferase in rat epididymis
Acta Histochem. Cytochem.
30
491-495
1997
Rattus norvegicus
-
Manually annotated by BRENDA team
Boeggeman, E.E.; Balajai, P.V.; Qasba, P.K.
Functional domains of bovine beta-1,4-galactosyltransferase
Glycoconjugate J.
12
865-878
1995
Bos taurus
Manually annotated by BRENDA team
Nishida, Y.; Tamakoshi, H.; Kitagawa, Y.; Kobayashi, K.; Thiem, J.
A novel bovine beta-1,4-galactosyltransferase reaction to yield beta-D-galactopyranosyl-(1-3)-linked disaccharides from L-sugars
Angew. Chem.
39
2000-2003
2000
Bos taurus
Manually annotated by BRENDA team
Malissard, M.; Borsig, L.; Di Marco, S.; Gruetter, M.G.; Kragl, U.; Wandrey, C.; Berger, E.G.
Recombinant soluble beta-1,4-galactosyltransferases expressed in Saccharomyces cerevisiae. Purification, characterization and comparison with human enzyme
Eur. J. Biochem.
239
340-348
1996
Homo sapiens
Manually annotated by BRENDA team
Park, J.E.; Lee, K.Y.; Do, S.I.; Lee, S.S.
Expression and characterization of beta-1,4-galactosyltransferase from Neisseria meningitidis and Neisseria gonorrhoeae
J. Biochem. Mol. Biol.
35
330-336
2002
Neisseria gonorrhoeae, Neisseria meningitidis
Manually annotated by BRENDA team
Boeggeman, E.; Qasba, P.K.
Studies on the metal binding sites in the catalytic domain of beta1,4-galactosyltransferase
Glycobiology
12
395-407
2002
Bos taurus
Manually annotated by BRENDA team
Ramakrishnan, B.; Boeggeman, E.; Qasba, P.K.
Effect of Met344His mutation on the conformational dynamics of bovine beta-1,4-galactosyltransferase: crystal structure of the Met344His mutant in complex with chitobiose
Biochemistry
43
12513-12522
2004
Bos taurus
Manually annotated by BRENDA team
Takamatsu, S.; Inoue, N.; Katsumata, T.; Nakamura, K.; Fujibayashi, Y.; Takeuchi, M.
The relationship between the branch-forming glycosyltransferases and cell surface sugar chain structures
Biochemistry
44
6343-6349
2005
Homo sapiens
Manually annotated by BRENDA team
Ramakrishnan, B.; Boeggeman, E.; Ramasamy, V.; Qasba, P.K.
Structure and catalytic cycle of beta-1,4-galactosyltransferase
Curr. Opin. Struct. Biol.
14
593-600
2004
Bos taurus, Homo sapiens
Manually annotated by BRENDA team
Ramasamy, V.; Ramakrishnan, B.; Boeggeman, E.; Qasba, P.K.
The role of tryptophan 314 in the conformational changes of beta1,4-galactosyltransferase-I
J. Mol. Biol.
331
1065-1076
2003
Bos taurus, Mus musculus
Manually annotated by BRENDA team
Alavi, A.; Axford, J.S.; Pool, A.J.
Serum galactosyltransferase isoform changes in rheumatoid arthritis
J. Rheumatol.
31
1513-1520
2004
Homo sapiens
Manually annotated by BRENDA team
Zhang, S.; Cai, M.; Zhang, S.W.; Hu, Y.; Gu, J.X.
Involvement of beta 1,4 galactosyltransferase I and Gal beta1-4GlcNAc groups in human hepatocarcinoma cell apoptosis
Mol. Cell. Biochem.
243
81-86
2003
Homo sapiens
Manually annotated by BRENDA team
Geshi, N.; Jorgensen, B.; Ulvskov, P.
Subcellular localization and topology of beta(1-4)galactosyltransferase that elongates beta(1-4)galactan side chains in rhamnogalacturonan I in potato
Planta
218
862-868
2004
Solanum tuberosum
Manually annotated by BRENDA team
Ishii, T.; Ohnishi-Kameyama, M.; Ono, H.
Identification of elongating beta-1,4-galactosyltransferase activity in mung bean (Vigna radiata) hypocotyls using 2-aminobenzaminated 1,4-linked beta-D-galactooligosaccharides as acceptor substrates
Planta
219
310-318
2004
Vigna radiata
Manually annotated by BRENDA team
Menzies, K.K.; Nicholas, K.R.
The expression of beta-1,3 galactosyltransferase and beta-1,4 galactosyltransferase enzymatic activities in the mammary gland of the tammar wallaby (Macropus eugenii) during early lactation
Biochim. Biophys. Acta
1770
115-120
2007
Notamacropus eugenii
Manually annotated by BRENDA team
Boeggeman, E.; Ramakrishnan, B.; Kilgore, C.; Khidekel, N.; Hsieh-Wilson, L.C.; Simpson, J.T.; Qasba, P.K.
Direct identification of nonreducing GlcNAc residues on N-glycans of glycoproteins using a novel chemoenzymatic method
Bioconjug. Chem.
18
806-814
2007
Homo sapiens
Manually annotated by BRENDA team
Chen, W.S.; Chang, H.Y.; Li, C.P.; Liu, J.M.; Huang, T.S.
Tumor beta-1,4-galactosyltransferase IV overexpression is closely associated with colorectal cancer metastasis and poor prognosis
Clin. Cancer Res.
11
8615-8622
2005
Homo sapiens
Manually annotated by BRENDA team
Brockhausen, I.; Benn, M.; Bhat, S.; Marone, S.; Riley, J.G.; Montoya-Peleaz, P.; Vlahakis, J.Z.; Paulsen, H.; Schutzbach, J.S.; Szarek, W.A.
UDP-Gal: GlcNAc-R beta1,4-galactosyltransferase - a target enzyme for drug design. Acceptor specificity and inhibition of the enzyme
Glycoconj. J.
23
525-541
2006
Bos taurus
Manually annotated by BRENDA team
Ramakrishnan, B.; Qasba, P.K.
Role of a single amino acid in the evolution of glycans of invertebrates and vertebrates
J. Mol. Biol.
365
570-576
2007
Drosophila melanogaster
Manually annotated by BRENDA team
Pisvejcova, A.; Rossi, C.; Husakova, L.; Kren, V.; Riva, S.; Monti, D.
beta-1,4-Galactosyltransferase-catalyzed glycosylation of sugar derivatives: Modulation of the enzyme activity by alpha-lactalbumin, immobilization and solvent tolerance
J. Mol. Catal. B
39
98-104
2006
Bos taurus
-
Manually annotated by BRENDA team
Li, Z.; Zong, H.; Kong, X.; Zhang, S.; Wang, H.; Sun, Q.; Gu, J.
Cell surface beta 1, 4-galactosyltransferase 1 promotes apoptosis by inhibiting epidermal growth factor receptor pathway
Mol. Cell. Biochem.
291
69-76
2006
Cricetulus griseus (Q99PC2)
Manually annotated by BRENDA team
Rhee, S.W.; Starr, T.; Forsten-Williams, K.; Storrie, B.
The steady-state distribution of glycosyltransferases between the Golgi apparatus and the endoplasmic reticulum is approximately 90:10
Traffic
6
978-990
2005
Homo sapiens
Manually annotated by BRENDA team
Bhaumik, S.K.; Singh, M.; Basu, R.; Bhaumik, S.; Roychoudhury, K.; Naskar, K.; Roy, S.; De, T.
Virulence attenuation of a UDP-galactose/N-acetylglucosamine beta1,4 galactosyltransferase expressing Leishmania donovani promastigote
Glycoconj. J.
25
459-472
2008
Leishmania donovani (A9XBL4), Leishmania donovani
Manually annotated by BRENDA team
Zhou, J.; Wei, Y.; Liu, D.; Ge, X.; Zhou, F.; Yun, X.; Jiang, J.; Gu, J.
Identification of beta 1,4GalT II as a target gene of p53-mediated HeLa cell apoptosis
J. Biochem.
143
547-554
2008
Homo sapiens (O60909)
Manually annotated by BRENDA team
Braundmeier, A.G.; Breed, W.G.; Miller, D.J.
Spermatozoa from a marsupial, the brushtail possum, contain beta1,4-galactosyltransferase
Reprod. Fertil. Dev.
20
402-407
2008
Trichosurus vulpecula
Manually annotated by BRENDA team
Bosco, M.; Le Gall, S.; Rihouey, C.; Couve-Bonnaire, S.; Bardor, M.; Lerouge, P.; Pannecoucke, X.
6-Azido D-galactose transfer to N-acetyl-D-glucosamine derivative using commercially available beta-1,4-galactosyltransferase
Tetrahedron Lett.
49
2294-2297
2008
Bos taurus
-
Manually annotated by BRENDA team
Bhaumik, S.K.; Singh, M.K.; Karmakar, S.; De, T.
UDP-Gal: N-acetylglucosamine beta 1-4 galactosyltransferase expressing live attenuated parasites as vaccine for visceral leishmaniasis
Glycoconj. J.
26
663-673
2009
Leishmania donovani (A9XBL4), Leishmania donovani AG83 / MHOM/IN/83/AG83 (A9XBL4)
Manually annotated by BRENDA team
Choi, H.J.; Chung, T.W.; Kim, C.H.; Jeong, H.S.; Joo, M.; Youn, B.; Ha, K.T.
Estrogen induced beta-1,4-galactosyltransferase 1 expression regulates proliferation of human breast cancer MCF-7 cells
Biochem. Biophys. Res. Commun.
426
620-625
2012
Homo sapiens
Manually annotated by BRENDA team
Lau, K.; Thon, V.; Yu, H.; Ding, L.; Chen, Y.; Muthana, M.M.; Wong, D.; Huang, R.; Chen, X.
Highly efficient chemoenzymatic synthesis of beta1-4-linked galactosides with promiscuous bacterial beta1-4-galactosyltransferases
Chem. Commun. (Camb. )
46
6066-6068
2010
Helicobacter pylori, Neisseria meningitidis
Manually annotated by BRENDA team
Ramakrishnan, B.; Qasba, P.K.
Crystal structure of the catalytic domain of Drosophila beta1,4-Galactosyltransferase-7
J. Biol. Chem.
285
15619-15626
2010
Drosophila melanogaster
Manually annotated by BRENDA team
Chang, H.H.; Chen, C.H.; Chou, C.H.; Liao, Y.F.; Huang, M.J.; Chen, Y.H.; Wang, W.J.; Huang, J.; Hung, J.S.; Ho, W.L.; Jeng, Y.M.; Che, M.I.; Lee, H.; Lu, M.Y.; Yang, Y.L.; Jou, S.T.; Lin, D.T.; Lin, K.H.; Hsu, W.M.; Huang, M.C.
beta-1,4-Galactosyltransferase III enhances invasive phenotypes via beta1-integrin and predicts poor prognosis in neuroblastoma
Clin. Cancer Res.
19
1705-1716
2013
Homo sapiens (P15291), Homo sapiens
Manually annotated by BRENDA team
Ramakrishnan, B.; Moncrief, A.J.; Davis, T.A.; Holland, L.A.; Qasba, P.K.
Investigations on beta1,4-galactosyltransferase I using 6-sulfo-GlcNAc as an acceptor sugar substrate
Glycoconj. J.
30
835-842
2013
Bos taurus (P08037)
Manually annotated by BRENDA team
Chatterjee, S.B.; Hou, J.; Bandaru, V.V.R.; Pezhouh, M.K.; Syed Rifat Mannan, A.A.; Sharma, R.
Lactosylceramide synthase beta-1,4-GalT-V A novel target for the diagnosis and therapy of human colorectal cancer
Biochem. Biophys. Res. Commun.
508
380-386
2019
Homo sapiens
Manually annotated by BRENDA team
Jiang, J.; Wagner, G.K.
An acceptor analogue of beta-1,4-galactosyltransferase Substrate, inhibitor, or both?
Carbohydr. Res.
450
54-59
2017
Bos taurus
Manually annotated by BRENDA team
Chen, F.; Chen, B.; Guan, W.; Chen, J.; Lv, Y.; Qiao, H.; Wang, C.; Zhang, Y.
Metabolic transition of milk lactose synthesis and up-regulation by AKT1 in sows from late pregnancy to lactation
Cell Biochem. Biophys.
75
131-138
2017
Sus scrofa
Manually annotated by BRENDA team
Jiang, J.; Kanabar, V.; Padilla, B.; Man, F.; Pitchford, S.C.; Page, C.P.; Wagner, G.K.
Uncharged nucleoside inhibitors of beta-1,4-galactosyltransferase with activity in cells
Chem. Commun. (Camb.)
52
3955-3958
2016
Homo sapiens
Manually annotated by BRENDA team
Miyazaki, T.; Miyashita, R.; Nakamura, S.; Ikegaya, M.; Kato, T.; Park, E.Y.
Biochemical characterization and mutational analysis of silkworm Bombyx mori beta-1,4-N-acetylgalactosaminyltransferase and insight into the substrate specificity of beta-1,4-galactosyltransferase family enzymes
Insect Biochem. Mol. Biol.
115
103254
2019
Bombyx mori (G1UHW5)
Manually annotated by BRENDA team
Song, H.B.; He, M.; Cai, Z.P.; Huang, K.; Flitsch, S.L.; Liu, L.; Voglmeir, J.
UDP-glucose 4-epimerase and ?-1,4-galactosyltransferase from the oyster Magallana gigas as valuable biocatalysts for the production of galactosylated products
Int. J. Mol. Sci.
19
1600
2018
Crassostrea gigas (K1QT40)
Manually annotated by BRENDA team
Cui, C.; Chen, X.; Liu, Y.; Cao, B.; Xing, Y.; Liu, C.; Yang, F.; Li, Y.; Yang, T.; Hua, L.; Tian, M.; Wei, Y.; Gong, Y.; Jiang, J.
beta1,4-Galactosyltransferase V activates Notch1 signaling in glioma stem-like cells and promotes their transdifferentiation into endothelial cells
J. Biol. Chem.
293
2219-2230
2018
Homo sapiens
Manually annotated by BRENDA team
Morokuma, D.; Xu, J.; Hino, M.; Mon, H.; Merzaban, J.S.; Takahashi, M.; Kusakabe, T.; Lee, J.M.
Expression and Characterization of human beta-1,4-galactosyltransferase 1 (beta4GalT1) using silkworm-baculovirus expression system
Mol. Biotechnol.
59
151-158
2017
Homo sapiens
Manually annotated by BRENDA team
Wei, H.; Xu, L.; Li, C.; Liu, L.; Ng, D.M.; Haleem, M.; Jiang, L.; Sun, N.; Ling, Q.; Ma, S.; Zhang, L.; Wang, Q.; Tao, T.
SSeCKS promoted lipopolysaccharide-sensitized astrocytes migration via increasing beta-1,4-galactosyltransferase-I activity
Neurochem. Res.
44
839-848
2019
Rattus norvegicus
Manually annotated by BRENDA team
Harrus, D.; Khoder-Agha, F.; Peltoniemi, M.; Hassinen, A.; Ruddock, L.; Kellokumpu, S.; Glumoff, T.
The dimeric structure of wild-type human glycosyltransferase B4GalT1
PLoS ONE
13
e0205571
2018
Homo sapiens
Manually annotated by BRENDA team