2.4.1.90: N-acetyllactosamine synthase

This is an abbreviated version!
For detailed information about N-acetyllactosamine synthase, go to the full flat file.

Word Map on EC 2.4.1.90

2.4.1.90

oligosaccharide

glycosyltransferases

galactosylation

n-glycans

alpha-lactalbumin

ganglioside

glycosphingolipids

zona

pellucida

glucosylceramide

laccer

zp3

sperm-egg

d-pdmp

ga2

poly-n-acetyllactosamine

udp-galnac

medicine

synthesis

biotechnology

Reaction

Synonyms

acetyllactosamine synthetase, B4GALT1, B4GALT3, B4GalT5, beta 1,4 galactosyltransferase I, beta 1,4-galactosyltransferase 1, beta 1,4GalT II, beta 1,4GTI, beta(1,4)-galactosyltransferase, beta(1,4)-GT, beta(1-4)galactosyltransferase, beta-1,4-galactosyltransferase, beta-1,4-galactosyltransferase 1, beta-1,4-galactosyltransferase III, beta-1,4-galactosyltransferase IV, beta-1,4-galactosyltransferase-1, beta-1,4-galactosyltransferase-I, beta-1,4-galactosyltransferase-V, beta-1,4-GalT, beta-1,4-GalT-I, beta-1,4-GalT-V, beta-1,4-GT-IV, beta-1,4-N-acetylgalactosaminyltransferase, beta-N-acetylglucosaminide beta1-4-galactosyltransferase, beta1,4-Gal-transferase T1, beta1,4-galactosyltransferase, beta1,4-galactosyltransferase I, beta1,4-galactosyltransferase II, beta1,4-galactosyltransferase V, beta1,4-galactosyltransferase-1, beta1,4-galactosyltransferase-7, beta1,4-galactosyltransferase-I, beta1,4-GT, beta1,4GalT II, beta1,4GalTV, beta1-4-galactosyltransferase, beta1-4GalT, beta4Gal-T, beta4Gal-T1, beta4Gal-T7, beta4GalT, beta4GalT1, betaGALT1, beta[1-4]GalT, EC 2.4.1.98, Gal-T, galactosyltransferase, uridine diphosphogalactose-acetylglucosamine, GalNAcT, GALT, GalT1, GalT7, GalTase, GalTase-I, GTase, Hp1-4GalT, lactosamine synthase, lactosamine synthetase, lactose synthetase A protein, lactosylceramide synthase, More, N-acetyllactosamine synthetase, NAL synthetase, NmLgtB, UDP-beta-1,4-galactosyltransferase, UDP-Gal:betaGlcNAc beta-1,4-galactosyltransferase, polypeptide 5, UDP-Gal:N-acetylglucosamine beta1-4-galactosyltransferase, UDP-galactose N-acetylglucosamine beta-4-galactosyltransferase, UDP-galactose-acetylglucosamine galactosyltransferase, UDP-galactose-N-acetylglucosamine beta-1,4-galactosyltransferase, UDP-galactose-N-acetylglucosamine galactosyltransferase, UDP-galactose/N-acetylglucosamine beta1,4 galactosyltransferase, UDP-galactose: N-acetylglucosamine beta 1-4 galactosyltransferase, UDP-galactose:N-acetylglucosaminide beta1-4-galactosyltransferase, UDPgalactose-N-acetylglucosamine beta-D-galactosyltransferase, UDPgalactose:N-acetylglucosaminyl(beta1-4)galactosyltransferase, uridine diphosphogalactose-acetylglucosamine galactosyltransferase

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.90 N-acetyllactosamine synthase

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Results	in table
36	Activating Compound
42	AA Sequence
10	Application
1	CAS Registry Number
31	Cloned(Commentary)
11	Crystallization (Commentary)
305	Disease/ Diagnostics
3	Expression
6	General Information
4	General Stability
15	IC50 Value
72	Inhibitors
2	Ki Value [mM]
85	KM Value [mM]
84	Localization
78	Metals/Ions
22	Molecular Weight [Da]
45	Natural Substrates/ Products (Substrates)
109	Organism
69	PDB ID
28	pH Optimum
2	pH Range
1	pH Stability
2	pI Value
8	Posttranslational Modification
42	Protein Variants
29	Purification (Commentary)
8	Reaction
1	Reaction Type
109	Reference
1	Renatured (Commentary)
125	Source Tissue
38	Specific Activity [micromol/min/mg]
13	Storage Stability
218	Substrates and Products (Substrate)
23	Subunits
109	Synonyms
1	Systematic Name
15	Temperature Optimum [°C]
1	Temperature Range [°C]
4	Temperature Stability [°C]
5	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 2.4.1.90 - N-acetyllactosamine synthase

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alpha-lactalbumin

7 entries

bovine serum albumin

Bos taurus

in the presence of 12.5 mg/ml bovine serum albumin, turnover rates increase approximately 2fold and Km values increase by approximately 4fold, for both N-acetyl-D-glucosamine and 1-(2-naphthyl) 2-acetamido-2-deoxy-beta-D-glucopyranoside

756352

dimyristoylphosphatidylcholine

2 entries

dioleoylphosphatidylcholine

Rattus norvegicus

activation

489513

dipalmitoylphosphatidylcholine

Rattus norvegicus

activation

489513

Distearoylphosphatidylcholine

activation

histone

activation

lysophosphatidylcholine

Bos taurus

activation

489511

Methylphosphatidylic acid

Bos taurus

activation

489511

phosphatidylcholine

2 entries

phosphatidylethanolamine

activation

phosphatidylglycerol

activation

poly(L-Arg)

activation

poly(L-Lys)

activation

Protamine sulfate

activation

Triton X-100

additional information

Notamacropus eugenii

the enzyme regulation/stimulation is a complex system involving the hormones insulin, prolactine, hydrocortisone, triiodothyronine, and 17beta-estradiol, andalso the extracellular matrix and the sucking stimulus

672411