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Literature summary for 2.4.1.90 extracted from

  • Zhou, J.; Wei, Y.; Liu, D.; Ge, X.; Zhou, F.; Yun, X.; Jiang, J.; Gu, J.
    Identification of beta 1,4GalT II as a target gene of p53-mediated HeLa cell apoptosis (2008), J. Biochem., 143, 547-554.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination and analysis, promoter activity analysis Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information decreasing the expression of beta1,4GalT II using RNA interference inhibits p53-mediated HeLa cell apoptosis induced by adriamycin Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens beta1,4-galactosyltransferase II is one of the enzymes transferring galactose to the terminal N-acetylglucosamine of complex-type N-glycans. Beta1,4GalT II might serve as a target gene of p53 transcription factor during adriamycin-induced HeLa cell apoptosis, mechanisms of its expression regulation, overview ?
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Organism

Organism UniProt Comment Textmining
Homo sapiens O60909
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Source Tissue

Source Tissue Comment Organism Textmining
HeLa cell
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Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information beta1,4-galactosyltransferase II is one of the enzymes transferring galactose to the terminal N-acetylglucosamine of complex-type N-glycans. Beta1,4GalT II might serve as a target gene of p53 transcription factor during adriamycin-induced HeLa cell apoptosis, mechanisms of its expression regulation, overview Homo sapiens ?
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Synonyms

Synonyms Comment Organism
beta 1,4GalT II
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Homo sapiens
beta1,4-galactosyltransferase II
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Homo sapiens
beta1,4GalT II
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Homo sapiens