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Literature summary for 2.4.1.90 extracted from

  • Takamatsu, S.; Inoue, N.; Katsumata, T.; Nakamura, K.; Fujibayashi, Y.; Takeuchi, M.
    The relationship between the branch-forming glycosyltransferases and cell surface sugar chain structures (2005), Biochemistry, 44, 6343-6349.
    View publication on PubMed
Search for more literature for 2.4.1.90

Application

Application Comment Organism
biotechnology enzyme can be useful in the glycosylation of cytokines, enzymes or other glycosylated compounds modifying their functions for use in medical therapies Homo sapiens
synthesis enzyme can be useful in the glycosylation of cytokines, enzymes or other glycosylated compounds modifying their functions for use in medical therapies Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
A-549 cell lung carcinoma cell line Homo sapiens
-
BALL-1 cell acute promyelocytic leukemia cell line Homo sapiens
-
BeWo cell choriocarcinoma cell line, high activity Homo sapiens
-
Burkitt lymphoma cell Namalwa cells Homo sapiens
-
Caco-2 cell colon adenocarcinoma cell line Homo sapiens
-
cervical carcinoma cell HeLaS3 cells Homo sapiens
-
choriocarcinoma cell BeWo cells, high activity Homo sapiens
-
colonic adenocarcinoma cell CACO-2 cells Homo sapiens
-
EoL-1 cell eosinophilic leukemia cell line, low activity Homo sapiens
-
eosinophilic leukemia cell EoL-1 cells, low activity Homo sapiens
-
erythroleukemia cell HEL cells Homo sapiens
-
HEL cell erythroid leukemia cell line Homo sapiens
-
HeLa-S3 cell cervical carcinoma cell line Homo sapiens
-
Hep-G2 cell hepatocellular carcinoma cell line Homo sapiens
-
hepatoma cell Hep-G2 cells Homo sapiens
-
HuO-3N1 cell
-
 Homo sapiens
-
HuO-3N1 cell osteosarcoma cell line Homo sapiens
-
KU-812 cell chronic myelogenous leukemia cell line Homo sapiens
-
lung cancer cell A-549 cells Homo sapiens
-
melanoma cell Bowes melanoma cell line Homo sapiens
-
MOLT-4 cell T cell leukemia cell line Homo sapiens
-
monocytic leukemia cell THP-1 cells Homo sapiens
-
myeloid leukemia cell chronic, KU-812 cells Homo sapiens
-
OS-RC-2 cell
-
 Homo sapiens
-
OS-RC-2 cell renal cell carcinoma cell line Homo sapiens
-
promyelocytic leukemia cell acute, BALL-1 cells Homo sapiens
-
T-24 cell urinary bladder carcinoma cell Homo sapiens
-
T-cell leukemia cell MOLT-4 cells Homo sapiens
-
THP-1 cell monocytic leukemia cell line Homo sapiens
-
urinary bladder carcinoma cell T-24 cell Homo sapiens
-
YMB-1 cell
-
 Homo sapiens
-
YMB-1 cell breast cancer cell line Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.00008
-
 EoL-1 cell extract Homo sapiens
0.00013
-
 KU-812 cell extract Homo sapiens
0.00014
-
 THP-1 cell extract, HEL cell extract, and HL-60 cell extract Homo sapiens
0.00015
-
 MOLT-4 cell extract Homo sapiens
0.00016
-
 Bowes melanoma cell extract Homo sapiens
0.00021
-
 T-24 cell extract Homo sapiens
0.00025
-
 HuO-3N1 cell extract Homo sapiens
0.00037
-
 Namalga cell extract Homo sapiens
0.00039
-
 HepG2 cell extract Homo sapiens
0.00044
-
 YMB-1 cell extract Homo sapiens
0.00053
-
 A-549 cell extract Homo sapiens
0.0006
-
 CACO-2 cell extract, and HeLaS3 cell extract Homo sapiens
0.00065
-
 BALL-1 cell extract Homo sapiens
0.00084
-
 OS-RC-2 cell extract Homo sapiens
0.00122
-
 BeWo cell extract Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information analysis of cell surface sugar chains in the cancer cell lines, overview Homo sapiens ?
-
 ?
UDP-galactose + GlcNAcbeta(1,2)Manalpha(1,6)(GlcNAcbeta(1,2)Manalpha(1,3))Manbeta(1,4)GlcNAcbeta(1,4)GlcNAc-PA
-
 Homo sapiens UDP + Galbeta1,4-GlcNAcbeta(1,2)Manalpha(1,6)(GlcNAcbeta(1,2)Manalpha(1,3))Manbeta(1,4)GlcNAcbeta(1,4)GlcNAc-PA
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2
-
 assay at Homo sapiens