Reference on EC 5.6.1.4 - minus-end-directed kinesin ATPase
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Endow, S.A.
Determinants of motor polarity in the kinesin proteins
Biophys. J.
68
271S-274S
1995
Aspergillus sp., Cricetulus griseus, Drosophila sp. (in: flies), Homo sapiens, Saccharomyces sp., Schizosaccharomyces pombe
Kuriyama, R.; Kofron, M.; Essner, R.; Kato, T.; Dragas-Granoic, S.; Omoto, C.K.; Khodjakov, A.
Characterization of a minus end-directed kinesin-like motor protein from cultured mammalian cells
J. Cell Biol.
129
1049-1059
1995
Arabidopsis sp., Aspergillus sp., Saccharomyces cerevisiae, Cricetulus griseus, Drosophila melanogaster, Homo sapiens
Song, H.; Endow, S.A.
Binding sites on microtubules of kinesin motors of the same or opposite polarity
Biochemistry
35
11203-11209
1996
Saccharomyces cerevisiae, Drosophila melanogaster, Drosophila sp. (in: flies), Xenopus laevis
Lane, J.D.; Allan, V.J.
Microtubule-based endoplasmic reticulum motility in Xenopus laevis: activation of membrane-associated kinesin during development
Mol. Biol.
10
1909-1922
1999
Xenopus laevis
Walker, R.A.; Salmon, E.D.; Endow, S.A.
The Drosophila claret segregation protein is a minus-end directed motor molecule
Nature
347
780-782
1990
Drosophila melanogaster
McDonald, H.B.; Stewart, R.J.; Goldstein, L.S.
The kinesin-like ncd protein of Drosophila is a minus end-directed microtubule motor
Cell
63
1159-1165
1990
Drosophila melanogaster
Endow, S.A.; Kang, S.J.; Satterwhite, L.L.; Rose, M.D.; Skeen, V.P.; Salmon, E.D.
Yeast Kar3 is a minus-end microtubule motor protein that destabilizes microtubules preferentially at the minus ends
EMBO J.
13
2708-2713
1994
Arabidopsis sp., Saccharomyces cerevisiae, Drosophila melanogaster
Middleton, K.; Carbon, J.
KAR3-encoded kinesin is a minus-end-directed motor that functions with centromere binding proteins (CBF3) on an in vitro yeast kinetochore
Proc. Natl. Acad. Sci. USA
91
7212-7216
1994
Saccharomyces cerevisiae, Drosophila melanogaster
Lombillo, V.A.; Stewart, R.J.; McIntosh, J.R.
Minus-end-directed motion of kinesin-coated microspheres driven by microtubule depolymerization
Nature
373
161-164
1995
Dictyostelium sp., Drosophila melanogaster, Homo sapiens, Tetrahymena sp.
Walker, R.A.
Ncd and kinesin motor domains interact with both alpha- and beta-tubulin
Proc. Natl. Acad. Sci. USA
92
5960-5964
1995
Drosophila melanogaster, Drosophila sp. (in: flies)
Shimizu, T.; Toyoshima, Y.Y.; Edamatsu, M.; Vale, R.D.
Comparison of the motile and enzymatic properties of two microtubule minus-end-directed motors, ncd and cytoplasmic dynein
Biochemistry
34
1575-1582
1995
Bos taurus, Doryteuthis pealeii, Drosophila melanogaster, Drosophila sp. (in: flies), Tetrahymena sp.
Thrower, D.A.; Jordan, M.A.; Schaar, B.T.; Yen, T.J.; Wilson, L.
Mitotic HeLa cells contain a CENP-E-associated minus end-directed microtubule motor
EMBO J.
14
918-926
1995
Dictyostelium sp., Homo sapiens, Xenopus laevis
Crevel, I.M.; Lockhart, A.; Cross, R.A.
Weak and strong states of kinesin and ncd
J. Mol. Biol.
257
66-76
1996
Saccharomyces cerevisiae, Drosophila melanogaster, Drosophila sp. (in: flies)
Blocker, A.; Severin, F.F.; Burkhardt, J.K.; Bingham, J.B.; Yu, H.; Olivo, J.C.; Schroer, T.A.; Hyman, A.A.; Griffiths, G.
Molecular requirements for bi-directional movement of phagosomes along microtubules
J. Cell Biol.
137
113-129
1997
Bos taurus, Gallus gallus, Mus musculus, Rattus norvegicus
Sharp, D.J.; Kuriyama, R.; Essner, R.; Baas, P.W.
Expression of a minus-end-directed motor protein induces Sf9 cells to form axon-like processes with uniform microtubule polarity orientation
J. Cell Sci.
110
2373-2380
1997
Cricetulus griseus
Henningsen, U.; Schliwa, M.
Reversal in the direction of movement of a molecular motor
Nature
389
93-96
1997
Neurospora crassa
Sablin, E.P.; Case, R.B.; Dai, S.C.; Hart, C.L.; Ruby, A.; Vale, R.D.; Fletterick, R.J.
Direction determination in the minus-end-directed kinesin motor ncd
Nature
395
813-816
1998
Drosophila melanogaster, Rattus norvegicus
Matuliene, J.; Essner, R.; Ryu, J.; Hamaguchi, Y.; Baas, P.W.; Haraguchi, T.; Hiraoka, Y.; Kuriyama, R.
Function of a minus-end-directed kinesin-like motor protein in mammalian cells
J. Cell Sci.
112
4041-4050
1999
Saccharomyces cerevisiae, Cricetulus griseus, Drosophila melanogaster, Homo sapiens, Mus musculus
Kozielski,F.; De Bonis, S.; Burmeister, W.P.; Cohen-Addad, C.; Wade, R.H.
The crystal structure of the minis-end-directed microtubule motor protein ncd reveals variable dimer conformations
Structure Fold. Des.
7
1407-1416
1999
Drosophila melanogaster
Mackey, A.T.; Gilbert, S.P.
Moving a microtubule may require two heads: a kinetic investigation of monomeric Ncd
Biochemistry
39
1346-1355
2000
Drosophila melanogaster
Marcus, A.I.; Ambrose, J.C.; Blickley, L.; Hancock, W.O.; Cyr, R.J.
Arabidopsis thaliana protein, ATK1, is a minus-end directed kinesin that exhibits non-processive movement
Cell Motil. Cytoskeleton
52
144-150
2002
Arabidopsis thaliana
Maddox, P.S.; Stemple, J.K.; Satterwhite, L.; Salmon, E.D.; Bloom, K.
The minus end-directed motor Kar3 is required for coupling dynamic microtubule plus ends to the cortical shmoo tip in budding yeast
Curr. Biol.
13
1423-1428
2003
Schizosaccharomyces pombe
Wendt, T.G.; Volkmann, N.; Skiniotis, G.; Goldie, K.N.; Muller, J.; Mandelkow, E.; Hoenger, A.
Microscopic evidence for a minus-end-directed power stroke in the kinesin motor ncd
EMBO J.
21
5969-5978
2002
Drosophila melanogaster
Yun, M.; Bronner, C.E.; Park, C.G.; Cha, S.S.; Park, H.W.; Endow, S.A.
Rotation of the stalk/neck and one head in a new crystal structure of the kinesin motor protein, Ncd
EMBO J.
22
5382-5389
2003
Drosophila melanogaster
Mackey, A.T.; Sproul, L.R.; Sontag, C.A.; Satterwhite, L.L.; Correia, J.J.; Gilbert, S.P.
Mechanistic analysis of the Saccharomyces cerevisiae kinesin Kar3
J. Biol. Chem.
279
51354-51361
2004
Saccharomyces cerevisiae
Noda, Y.; Okada, Y.; Saito, N.; Setou, M.; Xu, Y.; Zhang, Z.; Hirokawa, N.
KIFC3, a microtubule minus end-directed motor for the apical transport of annexin XIIIb-associated Triton-insoluble membranes
J. Cell Biol.
155
77-88
2001
Mus musculus
Khodjakov, A.; Copenagle, L.; Gordon, M.B.; Compton, D.A.; Kapoor, T.M.
Minus-end capture of preformed kinetochore fibers contributes to spindle morphogenesis
J. Cell Biol.
160
671-683
2003
Chlorocebus aethiops, Potorous tridactylus
Preuss, M.L.; Kovar, D.R.; Lee, Y.R.; Staiger, C.J.; Delmer, D.P.; Liu, B.
A plant-specific kinesin binds to actin microfilaments and interacts with cortical microtubules in cotton fibers
Plant Physiol.
136
3945-3955
2004
Gossypium hirsutum (Q5MNW6), Gossypium hirsutum
Robin, G.; DeBonis, S.; Dornier, A.; Cappello, G.; Ebel, C.; Wade, R.H.; Thierry-Mieg, D.; Kozielski, F.
Essential kinesins: characterization of Caenorhabditis elegans KLP-15
Biochemistry
44
6526-6536
2005
Caenorhabditis elegans
Sproul, L.R.; Anderson, D.J.; Mackey, A.T.; Saunders, W.S.; Gilbert, S.P.
Cik1 targets the minus-end kinesin depolymerase Kar3 to microtubule plus ends
Curr. Biol.
15
1420-1427
2005
Saccharomyces cerevisiae
Chu, H.M.; Yun, M.; Anderson, D.E.; Sage, H.; Park, H.W.; Endow, S.A.
Kar3 interaction with Cik1 alters motor structure and function
EMBO J.
24
3214-3223
2005
Saccharomyces cerevisiae
Goshima, G.; Nedelec, F.; Vale, R.D.
Mechanisms for focusing mitotic spindle poles by minus end-directed motor proteins
J. Cell Biol.
171
229-240
2005
Drosophila melanogaster
Ito, M.; Morii, H.; Shimizu, T.; Tanokura, M.
Coiled coil in the stalk region of ncd motor protein is nonlocally sustained
Biochemistry
45
3315-3324
2006
Drosophila melanogaster
Hirose, K.; Akimaru, E.; Akiba, T.; Endow, S.A.; Amos, L.A.
Large conformational changes in a kinesin motor catalyzed by interaction with microtubules
Mol. Cell
23
913-923
2006
Saccharomyces cerevisiae
Endres, N.F.; Yoshioka, C.; Milligan, R.A.; Vale, R.D.
A lever-arm rotation drives motility of the minus-end-directed kinesin Ncd
Nature
439
875-878
2006
Drosophila melanogaster
Friedman, M.A.; Zeiger, E.; Marroni, D.E.; Sickles, D.W.
Inhibition of rat testicular nuclear kinesins (krp2; KIFC5A) by acrylamide as a basis for establishing a genotoxicity threshold
J. Agric. Food Chem.
56
6024-6030
2008
Rattus norvegicus
Furuta, K.; Edamatsu, M.; Maeda, Y.; Toyoshima, Y.Y.
Diffusion and directed movement: in vitro motile properties of fission yeast kinesin-14 Pkl1
J. Biol. Chem.
283
36465-36473
2008
Schizosaccharomyces pombe
Cai, S.; Weaver, L.N.; Ems-McClung, S.C.; Walczak, C.E.
Kinesin-14 family proteins HSET/XCTK2 control spindle length by cross-linking and sliding microtubules
Mol. Biol. Cell
20
1348-1359
2009
Homo sapiens, Xenopus laevis
Braun, M.; Drummond, D.R.; Cross, R.A.; McAinsh, A.D.
The kinesin-14 Klp2 organizes microtubules into parallel bundles by an ATP-dependent sorting mechanism
Nat. Cell Biol.
11
724-730
2009
Schizosaccharomyces pombe
Kocik, E.; Skowronek, K.J.; Kasprzak, A.A.
Interactions between subunits in heterodimeric Ncd molecules
J. Biol. Chem.
284
35735-35745
2009
Drosophila melanogaster
Hou, R.; Wang, Z.
A coordinated molecular fishing mechanism in heterodimeric kinesin
Phys. Biol.
7
036003
2010
Saccharomyces cerevisiae
Heuston, E.; Bronner, C.E.; Kull, F.J.; Endow, S.A.
A kinesin motor in a force-producing conformation
BMC Struct. Biol.
10
19
2010
Drosophila melanogaster
Szczesna, E.; Kasprzak, A.A.
The C-terminus of kinesin-14 Ncd is a crucial component of the force generating mechanism
FEBS Lett.
586
854-858
2012
Drosophila melanogaster
Chen, C.J.; Rayment, I.; Gilbert, S.P.
Kinesin Kar3Cik1 ATPase pathway for microtubule cross-linking
J. Biol. Chem.
286
29261-29272
2011
Saccharomyces cerevisiae (P17119), Saccharomyces cerevisiae
Hentrich, C.; Surrey, T.
Microtubule organization by the antagonistic mitotic motors kinesin-5 and kinesin-14
J. Cell Biol.
189
465-480
2010
Xenopus laevis (P79955), Xenopus laevis
Duan, D.; Hnatchuk, D.; Brenner, J.; Davis, D.; Allingham, J.
Crystal structure of the Kar3-like kinesin motor domain from the filamentous fungus Ashbya gossypii
Proteins Struct. Funct. Bioinform.
80
1016-1027
2012
Eremothecium gossypii
Dietrich, D.; Seiler, F.; Essmann, F.; Dodt, G.
Identification of the kinesin KifC3 as a new player for positioning of peroxisomes and other organelles in mammalian cells
Biochim. Biophys. Acta
1833
3013-3024
2013
Homo sapiens
Chen, C.J.; Porche, K.; Rayment, I.; Gilbert, S.P.
The ATPase pathway that drives the kinesin-14 Kar3Vik1 powerstroke
J. Biol. Chem.
287
36673-36682
2012
Saccharomyces cerevisiae (P17119), Saccharomyces cerevisiae
Locke, J.; Joseph, A.P.; Pena, A.; Moeckel, M.M.; Mayer, T.U.; Topf, M.; Moores, C.A.
Structural basis of human kinesin-8 function and inhibition
Proc. Natl. Acad. Sci. USA
114
E9539-E9548
2017
Homo sapiens (Q8NI77)
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