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Literature summary for 5.6.1.4 extracted from

  • Mackey, A.T.; Gilbert, S.P.
    Moving a microtubule may require two heads: a kinetic investigation of monomeric Ncd (2000), Biochemistry, 39, 1346-1355.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
pET/MC1 and pET/MC6 encoding dimeric and monomeric ncd expressed in Escherichia coli Bl21(DE3) Drosophila melanogaster

Crystallization (Commentary)

Crystallization (Comment) Organism
-
Drosophila melanogaster

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0278
-
ATP
-
Drosophila melanogaster

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + a kinesin associated with a microtubule at position n Drosophila melanogaster
-
ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
-
-

Purification (Commentary)

Purification (Comment) Organism
MC1 and MC6 Drosophila melanogaster

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
Drosophila melanogaster
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + a kinesin associated with a microtubule at position n
-
Drosophila melanogaster ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
?

Subunits

Subunits Comment Organism
dimer
-
Drosophila melanogaster
monomer
-
Drosophila melanogaster

Synonyms

Synonyms Comment Organism
MC1 dimeric ncd Drosophila melanogaster
MC6 monomeric ncd Drosophila melanogaster
ncd
-
Drosophila melanogaster