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Literature summary for 5.6.1.4 extracted from

  • Friedman, M.A.; Zeiger, E.; Marroni, D.E.; Sickles, D.W.
    Inhibition of rat testicular nuclear kinesins (krp2; KIFC5A) by acrylamide as a basis for establishing a genotoxicity threshold (2008), J. Agric. Food Chem., 56, 6024-6030.
    View publication on PubMed
Search for more literature for 5.6.1.4

Inhibitors

Inhibitors Comment Organism Structure
Acrylamide kinesin inhibition is observed at acrylamide concentrations as low as 0.1 mM Rattus norvegicus
glycidamide kinesin inhibition is observed at glycidamide concentrations as low as 0.1 mM Rattus norvegicus
Propionamide weak inhibition Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus
-
 Rattus norvegicus 5634
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
testis
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + a kinesin associated with a microtubule at position n
-
 Rattus norvegicus ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
 ?

Synonyms

Synonyms Comment Organism
KIFC5A a C-terminal motor, which belongs to a family of kinesins that move toward the minus end of the microtubules Rattus norvegicus
kinesin
-
 Rattus norvegicus