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Literature summary for 5.6.1.4 extracted from

  • Crevel, I.M.; Lockhart, A.; Cross, R.A.
    Weak and strong states of kinesin and ncd (1996), J. Mol. Biol., 257, 66-76.
    View publication on PubMed
Search for more literature for 5.6.1.4

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O + a kinesin associated with a microtubule at position n Drosophila melanogaster
-
 ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
 ?
ATP + H2O + a kinesin associated with a microtubule at position n Drosophila sp. (in: flies)
-
 ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
 ?
ATP + H2O + a kinesin associated with a microtubule at position n Saccharomyces cerevisiae
-
 ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
 ?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
-
-
Drosophila sp. (in: flies)
-
-
-
Saccharomyces cerevisiae
-
-
-

Reaction

Reaction Comment Organism Reaction ID
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end) structurally almost identical to EC3.6.4.3 (microtubule-severing ATPase) but the movement it catalyses is towards the minus end of microtubules Drosophila melanogaster
a
ATP + H2O + a kinesin associated with a microtubule at position n = ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end) structurally almost identical to EC3.6.4.3 (microtubule-severing ATPase) but the movement it catalyses is towards the minus end of microtubules Saccharomyces cerevisiae
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O + a kinesin associated with a microtubule at position n
-
 Drosophila melanogaster ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
 ?
ATP + H2O + a kinesin associated with a microtubule at position n
-
 Drosophila sp. (in: flies) ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
 ?
ATP + H2O + a kinesin associated with a microtubule at position n
-
 Saccharomyces cerevisiae ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
 ?
ATP + H2O + a kinesin associated with a microtubule at position n ncd switches from weak to strong binding via ADP release, and back again via ADP trapping Drosophila sp. (in: flies) ADP + phosphate + a kinesin associated with a microtubule at position n-1 (toward the minus end)
-
 ?

Synonyms

Synonyms Comment Organism
MT minus-end-directed non claret disjunctional
-
 Drosophila sp. (in: flies)
ncd
-
 Drosophila melanogaster
ncd
-
 Drosophila sp. (in: flies)