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Information on EC 4.6.1.16 - tRNA-intron lyase

for references in articles please use BRENDA:EC4.6.1.16
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EC Tree
IUBMB Comments
The enzyme catalyses the final stage in the maturation of tRNA molecules.
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Word Map
  • 4.6.1.16
  • home
  • endonucleases
  • laglidadg
  • inteins
  • pre-trnas
  • self-splicing
  • selfish
  • i-ppoi
  • giy-yig
  • intron-containing
  • i-crei
  • intronless
  • pi-scei
  • ribozyme
  • physarum
  • molecular biology
  • free-standing
  • meganuclease
  • iridis
  • overhang
  • endonucleolytic
  • maturase
  • pontocerebellar
  • degeneracy
The enzyme appears in viruses and cellular organisms
Reaction Schemes
pretRNA
=
a 3'-half-tRNA molecule with a 5'-OH end
+
a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end
+
an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
Synonyms
homing endonuclease, i-tevi, splicing endonuclease, trna splicing endonuclease, hspc117, intron-encoded endonuclease, hclp1, trna-splicing endonuclease, af endonuclease, rna splicing endonuclease, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
pretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
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PATHWAY SOURCE
PATHWAYS
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