EC Number   |
Protein Variants |
Reference |
|---|
   4.6.1.16 | C122A |
inactive |
730963 |
| 4.6.1.16 | D357A |
site-directed mutagenesis |
718175 |
| 4.6.1.16 | D49A |
site-directed mutagenesis, the mutation does not affect the enzyme activity |
717994 |
| 4.6.1.16 | E43A |
site-directed mutagenesis, the mutation does not affect the enzyme activity |
717994 |
| 4.6.1.16 | E51A |
site-directed mutagenesis, the mutation does not affect the enzyme activity |
717994 |
| 4.6.1.16 | F50A |
site-directed mutagenesis, the mutant shows reduced enzyme activity compared to the wild-type enzyme |
717994 |
| 4.6.1.16 | H133A |
site-directed mutagenesis, a catalytic site mutant, crystal structure determination |
717994 |
| 4.6.1.16 | H133A |
site-directed mutagenesis, crystal structure determination |
718174 |
| 4.6.1.16 | H136A |
site-directed mutagenesis of the catalytically essential residue results in an inactive mutant |
666060 |
| 4.6.1.16 | H257A |
residue of the catalytic triad, 28-fold reduction in activity |
690922 |
