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Literature summary for 4.6.1.16 extracted from

  • Dhungel, N.; Hopper, A.K.
    Beyond tRNA cleavage: novel essential function for yeast tRNA splicing endonuclease unrelated to tRNA processing (2012), Genes Dev., 26, 503-514.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.6.1.16

Protein Variants

Protein Variants Comment Organism
H297A catalytically inactive Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Saccharomyces cerevisiae 5737
-
mitochondrion
-
 Saccharomyces cerevisiae 5739
-
nucleus
-
 Saccharomyces cerevisiae 5634
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pretRNA Saccharomyces cerevisiae
-
 a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pretRNA
-
 Saccharomyces cerevisiae a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus
-
 ?

Synonyms

Synonyms Comment Organism
Sen2 catalytic core of the enzyme complex Saccharomyces cerevisiae
tRNA SEN
-
 Saccharomyces cerevisiae
tRNA splicing endonuclease
-
 Saccharomyces cerevisiae