Literature summary for 4.6.1.16 extracted from

Trotta, C.R.; Miao, F.; Arn, E.A.; Stevens, S.W.; Ho, C.K.; Rauhut, R.; Abelson, J.N.
The yeast tRNA splicing endonuclease: a tetrameric enzyme with two active site subunits homologous to the archaeal tRNA endonucleases (1997), Cell, 89, 849-858.

Search for more literature for 4.6.1.16

Cloned(Commentary)

Cloned (Comment)	Organism
genes of all four subunits, each of them being essential	Saccharomyces cerevisiae

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
146000	-	deduced from gene sequences of subunits	Saccharomyces cerevisiae

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	enzyme contains two functionally independent active sites for 5 and 3 splicing	Saccharomyces cerevisiae	?	-	?
tRNA precursor	-	Saccharomyces cerevisiae	a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus	-	?

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Release 2023.1 (January 2023)