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Information on EC 3.4.24.65 - macrophage elastase

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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.65 macrophage elastase
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
Hydrolysis of soluble and insoluble elastin. Specific cleavages are also produced at -Ala14-/-Leu- and -Tyr16-/-Leu- in the B chain of insulin
Synonyms
mmp-12, mmp12, matrix metalloproteinase-12, metalloelastase, matrix metalloproteinase 12, macrophage metalloelastase, human macrophage metalloelastase, hmmp-12, mouse macrophage metalloelastase, human macrophage elastase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Hydrolysis of soluble and insoluble elastin. Specific cleavages are also produced at -Ala14-/-Leu- and -Tyr16-/-Leu- in the B chain of insulin
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