Literature summary for 3.4.24.65 extracted from

Wei, P.C.; Tsai, C.H.; Chiu, P.S.; Lai, S.C.
Matrix metalloproteinase-12 leads to elastin degradation in BALB/c mice with eosinophilic meningitis caused by Angiostrongylus cantonensis (2011), Int. J. Parasitol., 41, 1175-1183.

Search for more literature for 3.4.24.65

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
cerebrovascular endothelial cell	MMP-12/tissue inhibitor of metalloproteinase-1 ratio is significantly increased in the CSF of Angiostrongylus cantonensis-infected mice from day 10 p.i., and reaches high levels on days 20 and 25 p.i. MMP-12 production is correlated with elastin degradation, eosinophil count, blood-CSF barrier permeability and pathological changes in the subarachnoid space	Mus musculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Elastin + H2O	-	Mus musculus	?	-	?

Synonyms

Synonyms	Comment	Organism
MMP-12	-	Mus musculus

Expression

Organism	Comment	Expression
Mus musculus	MMP-12/tissue inhibitor of metalloproteinase-1 ratio is significantly increased in the CSF of Angiostrongylus cantonensis-infected mice from day 10 p.i., and reaches high levels on days 20 and 25 p.i. MMP-12 production is correlated with elastin degradation, eosinophil count, blood-CSF barrier permeability and pathological changes in the subarachnoid space	up

General Information

General Information	Comment	Organism
physiological function	MMP-12 leads to elastin degradation in BALB/c mice with eosinophilic meningitis caused by Angiostrongylus cantonensis	Mus musculus

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Release 2023.1 (January 2023)