EC Number |
Expression |
Reference |
---|
3.4.24.65 | more |
failure of dexamethasone treatment in MMP-12 suppression in the lungs |
-, 754337 |
3.4.24.65 | up |
metalloproteinase 12 (MMP-12) is induced in chondrocytes during fetal development and malignant transformation |
754996 |
3.4.24.65 | up |
MMP-12 expression is upregulated by other matrix components such as hyaluronan fragments, cytokines, and growth factors, for example by TGF-beta, IFN-gamma and EGF, and serine proteases such as thrombin and plasmin |
708452 |
3.4.24.65 | up |
MMP-12/tissue inhibitor of metalloproteinase-1 ratio is significantly increased in the CSF of Angiostrongylus cantonensis-infected mice from day 10 p.i., and reaches high levels on days 20 and 25 p.i. MMP-12 production is correlated with elastin degradation, eosinophil count, blood-CSF barrier permeability and pathological changes in the subarachnoid space |
717684 |
3.4.24.65 | up |
UV radiation is known to induce the expression of MMP-12 in skin |
708422 |