Literature summary for 3.4.24.65 extracted from

Liang, J.; Liu, E.; Yu, Y.; Kitajima, S.; Koike, T.; Jin, Y.; Morimoto, M.; Hatakeyama, K.; Asada, Y.; Watanabe, T.; Sasaguri, Y.; Watanabe, S.; Fan, J.
Macrophage metalloelastase accelerates the progression of atherosclerosis in transgenic rabbits (2006), Circulation, 113, 1993-2001.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	macrophage-derived overexpression of MMP-12 causes accelerated atherosclerosis. Overexpression of human MMP-12 in macrophages of rabbits results in enhanced atherosclerosis	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	MMP-12 expressed in Oryctolagus cuniculus	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	macrophage-derived overexpression of MMP-12 causes accelerated atherosclerosis. Overexpression of human MMP-12 in macrophages of rabbits results in enhanced atherosclerosis	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
MMP-12	-	Homo sapiens

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Release 2023.1 (January 2023)