Information on EC - biotin-[biotin carboxyl-carrier protein] ligase

for references in articles please use BRENDA:EC6.3.4.15
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IUBMB Comments
The enzyme biotinylates a biotin carboxyl-carrier protein that is part of an acetyl-CoA carboxylase complex, enabling its subsequent carboxylation by EC, biotin carboxylase. The carboxyl group is eventually transferred to acetyl-CoA by EC, acetyl-CoA carboxytransferase. In some organisms the carrier protein is part of EC, acetyl-CoA carboxylase.
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The enzyme appears in viruses and cellular organisms
Acetyl CoA holocarboxylase synthetase, Acetyl coenzyme A holocarboxylase synthetase, bacterial BirA biotin ligase, biotin acetyl-CoA carboxylase ligase, Biotin holoenzyme synthetase, biotin ligase, biotin protein ligase, Biotin--protein ligase, biotin-protein ligase, Biotin-[acetyl coenzyme A carboxylase] synthetase, more
ATP + biotin + [biotin carboxyl-carrier protein]-L-lysine = AMP + diphosphate + [biotin carboxyl-carrier protein]-N6-biotinyl-L-lysine
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