EC Number   |
Ki Value [mM] |
Ki Value maximum [mM] |
Inhibitor |
Reference |
|---|
    6.3.4.15 | 0.00009 |
- |
5-methyl-3-[4-(4-[5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentyl]-1H-1,2,3-triazol-1-yl)butyl]-1,3-benzoxazol-2(3H)-one |
wild type enzyme, at pH 7.5 and 37°C |
727901 |
| 6.3.4.15 | 0.0003 |
- |
biotin acetylene |
wild type enzyme, pH and temperature not specified in the publication |
728338 |
| 6.3.4.15 | 0.00117 |
- |
(3aS,4S,6aR)-4-[-[1-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl]triazol-4-yl]pentyl]-1,3,3a,4,6,6ahexahydrothieno[3,4-d]imidazol-2-one |
wild type enzyme, at pH 7.5 and 37°C |
727901 |
| 6.3.4.15 | 0.0017 |
- |
(3aS,4S,6aR)-4-(5-[1-[4-(naphthalen-2-yloxy)butyl]-1H-1,2,3-triazol-4-yl]pentyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one |
wild type enzyme, at pH 7.5 and 37°C |
727901 |
| 6.3.4.15 | 0.0072 |
- |
biotin acetylene |
mutant enzyme F123G, pH and temperature not specified in the publication |
728338 |
| 6.3.4.15 | 0.0076 |
- |
biotin acetylene |
mutant enzyme F123R, pH and temperature not specified in the publication |
728338 |
| 6.3.4.15 | 0.01 |
- |
(3aS,4S,6aR)-4-(5-[1-[3-(naphthalen-2-yloxy)propyl]-1H-1,2,3-triazol-4-yl]pentyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one |
Ki above 0.01 mM, wild type enzyme, at pH 7.5 and 37°C |
727901 |
| 6.3.4.15 | 0.01 |
- |
(3aS,4S,6aR)-4-(5-[1-[4-(naphthalen-1-yloxy)butyl]-1H-1,2,3-triazol-4-yl]pentyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one |
Ki above 0.01 mM, wild type enzyme, at pH 7.5 and 37°C |
727901 |
| 6.3.4.15 | 0.01 |
- |
(3aS,4S,6aR)-4-[5-[1-(4-phenoxybutyl)-1H-1,2,3-triazol-4-yl]pentyl]tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one |
Ki above 0.01 mM, wild type enzyme, at pH 7.5 and 37°C |
727901 |
| 6.3.4.15 | 0.01 |
- |
2-(4-[5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentyl]-1H-1,2,3-triazol-1-yl)ethyl 2,2-dimethylpropanoate |
Ki above 0.01 mM, wild type enzyme, at pH 7.5 and 37°C |
727901 |
