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Literature summary for 6.3.4.15 extracted from

  • Wijeratne, S.S.; Camporeale, G.; Zempleni, J.
    K12-biotinylated histone H4 is enriched in telomeric repeats from human lung IMR-90 fibroblasts (2010), J. Nutr. Biochem., 21, 310-316.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + biotin + apo-[acetyl-CoA carboxylase 1] Homo sapiens cytoplasmic acetyl-CoA carboxylase isozyme AMP + diphosphate + acetyl-CoA carboxylase 1
-
?
ATP + biotin + apo-[acetyl-CoA carboxylase 2] Homo sapiens mitochondrial acetyl-CoA carboxylase isozyme AMP + diphosphate + acetyl-CoA carboxylase 2
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?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast
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Homo sapiens
-
IMR-90 cell lung fibroblasts, quantitative determination of HCS in wild-type IMR-90 fibroblasts and in those recombinantly overexpressing human telomerase, evaluation as a cell model for investigation of HCS in epigenetic regulation, histone biotinylation in aging cells, overview Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + biotin + apo-[acetyl-CoA carboxylase 1] cytoplasmic acetyl-CoA carboxylase isozyme Homo sapiens AMP + diphosphate + acetyl-CoA carboxylase 1
-
?
ATP + biotin + apo-[acetyl-CoA carboxylase 2] mitochondrial acetyl-CoA carboxylase isozyme Homo sapiens AMP + diphosphate + acetyl-CoA carboxylase 2
-
?

Synonyms

Synonyms Comment Organism
HCS
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Homo sapiens
Holocarboxylase synthetase
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Homo sapiens