EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
6.3.4.15 | (4S)-4-(hept-6-yn-1-yl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one + 9-(4-azidobutyl)-9H-purin-6-amine |
i.e. reaction of acetylene derivative of biotin and an azide-functionalized adenine |
Staphylococcus aureus |
(4S)-4-(5-[1-[4-(6-amino-9H-purin-9-yl)butyl]-1H-1,2,3-triazol-4-yl]pentyl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one |
- |
? |
6.3.4.15 | (4S)-4-(hept-6-yn-1-yl)tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one + N-(3-azidopropyl)-7-nitro-2,1,3-benzoxadiazol-4-amine |
i.e. reaction of acetylene derivative of biotin and an azide-functionalied analogue of the fluorophore nitrobenzofurazan |
Staphylococcus aureus |
(4S)-4-[5-(1-[3-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]propyl]-1H-1,2,3-triazol-4-yl)pentyl]tetrahydro-1H-thieno[3,4-d]imidazol-2(3H)-one |
- |
? |
6.3.4.15 | ATP + biotin + AccB-86 |
AccB, i.e. acetyl-CoA carboxylase biotin carboxyl carrier protein biotin attachment domain |
Bacillus subtilis |
AMP + diphosphate + biotinylated AccB-86 |
- |
? |
6.3.4.15 | ATP + biotin + AccB-86 |
AccB, i.e. acetyl-CoA carboxylase biotin carboxyl carrier protein biotin attachment domain |
Bacillus subtilis 168 |
AMP + diphosphate + biotinylated AccB-86 |
- |
? |
6.3.4.15 | ATP + biotin + apo-[acetyl CoA carboxylase] |
no coupling is observed in ATP and biotin binding to the BPL |
Pyrococcus horikoshii |
AMP + diphosphate + acetyl CoA carboxylase |
- |
? |
6.3.4.15 | ATP + biotin + apo-[acetyl-CoA carbon-dioxide ligase] |
- |
Mycobacterium tuberculosis |
AMP + diphosphate + [acetyl-CoA:carbon-dioxide ligase] |
- |
? |
6.3.4.15 | ATP + biotin + apo-[acetyl-CoA carbon-dioxide ligase] |
- |
Mycobacterium tuberculosis H37Rv |
AMP + diphosphate + [acetyl-CoA:carbon-dioxide ligase] |
- |
? |
6.3.4.15 | ATP + biotin + apo-[acetyl-CoA carboxylase 1] |
cytoplasmic acetyl-CoA carboxylase isozyme |
Homo sapiens |
AMP + diphosphate + acetyl-CoA carboxylase 1 |
- |
? |
6.3.4.15 | ATP + biotin + apo-[acetyl-CoA carboxylase 2] |
mitochondrial acetyl-CoA carboxylase isozyme |
Homo sapiens |
AMP + diphosphate + acetyl-CoA carboxylase 2 |
- |
? |
6.3.4.15 | ATP + biotin + apo-[acetyl-CoA carboxylase 2] |
i.e. ACC2, substrate is the recombinantly expressed His-tagged biotinoyl domain, ACC75, of ACC2, comprising residues 891-965. hHCS recognizes the MKM motif, NMR binding study, binding pattern, overview |
Homo sapiens |
AMP + diphosphate + acetyl-CoA carboxylase 2 |
- |
? |