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Information on EC 3.6.4.6 - vesicle-fusing ATPase

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IUBMB Comments
A large family of ATP-hydrolysing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. They belong to the AAA-type (_A_TPase _a_ssociated with a variety of cell _a_ctivities) ATPase superfamily. They include peroxin, which apparently is involved in Zellweger's syndrome.
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
Synonyms
n-ethylmaleimide-sensitive factor, cdc48, aaa-atpase, n-ethylmaleimide-sensitive fusion protein, n-ethylmaleimide sensitive factor, atp6v0d2, sec18p, sec18, cdc48p, pex1p, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
ATP + H2O = ADP + phosphate
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