EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.6.4.6 | Adenocarcinoma of Lung |
30431439 |
Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2?-mediated tumor progression. |
causal interaction
ongoing research
unassigned |
3
2
0 |
| 3.6.4.6 | Alzheimer Disease |
11244216 |
Synaptosomal proteins, beta-soluble N-ethylmaleimide-sensitive factor attachment protein (beta-SNAP), gamma-SNAP and synaptotagmin I in brain of patients with Down syndrome and Alzheimer's disease. |
unassigned |
0 |
| 3.6.4.6 | Alzheimer Disease |
31223056 |
MAPT/Tau accumulation represses autophagy flux by disrupting IST1-regulated ESCRT-III complex formation: a vicious cycle in Alzheimer neurodegeneration. |
unassigned |
0 |
| 3.6.4.6 | Amyotrophic Lateral Sclerosis |
26134898 |
An ALS disease mutation in Cdc48/p97 impairs 20S proteasome binding and proteolytic communication. |
causal interaction
unassigned |
1
0 |
| 3.6.4.6 | Amyotrophic Lateral Sclerosis |
32686621 |
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 3.6.4.6 | Apraxias |
32686621 |
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 3.6.4.6 | Arthritis, Rheumatoid |
27623077 |
AAA-ATPase p97 suppresses apoptotic and autophagy-associated cell death in rheumatoid arthritis synovial fibroblasts. |
causal interaction
ongoing research
unassigned |
2
3
0 |
| 3.6.4.6 | Asthma |
33733641 |
ATP6V0d2 Suppresses Alveoli Macrophage Alternative Polarization and Allergic Asthma via Degradation of PU.1. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
4
2
4
1 |
| 3.6.4.6 | Ataxia |
32686621 |
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 3.6.4.6 | Bacterial Infections |
11092884 |
Requirement for N-ethylmaleimide-sensitive factor activity at different stages of bacterial invasion and phagocytosis. |
ongoing research
unassigned |
3
0 |
