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Literature summary for 3.6.4.6 extracted from

  • Fujita, H.; Umezuki, Y.; Imamura, K.; Ishikawa, D.; Uchimura, S.; Nara, A.; Yoshimori, T.; Hayashizaki, Y.; Kawai, J.; Ishidoh, K.; Tanaka, Y.; Himeno, M.
    Mammalian class E Vps proteins, SBP1 and mVps2/CHMP2A, interact with and regulate the function of an AAA-ATPase SKD1/Vps4B (2004), J. Cell Sci., 117, 2997-3009.
    View publication on PubMed
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Activating Compound

Activating Compound Comment Organism Structure
additional information SKD1 E Vps proteins SBP1 and mVps2 interact with SKD1 Mus musculus

Cloned(Commentary)

Cloned (Comment) Organism
expression in rat 3Y1B fibroblast cells Mus musculus

Protein Variants

Protein Variants Comment Organism
E235Q no ATPase activity, mutation leads to perturbation of various membrane transports via endosomes Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + H2O Mus musculus
-
 ADP + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + H2O
-
 Mus musculus ADP + phosphate
-
 ?
ATP + H2O involved in membrane transport through endosome Mus musculus ADP + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
SKD1
-
 Mus musculus
suppresor of potassium transport growth defect
-
 Mus musculus
vacular protein sorting 4 B
-
 Mus musculus
Vps 4B
-
 Mus musculus